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カタログ番号 | 製品名 | 別名 | ターゲット |
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T2226 | Pergolide mesylate | Pergolide mesylate salt,LY127809,Pergolide methanesulfonate | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
Pergolide mesylate salt(LY127809) is a long-acting dopamine agonist which has been used to treat PARKINSON DISEASE and HYPERPROLACTINEMIA but withdrawn from some markets due to potential for HEART VALVE DISEASES. | |||
T4117 | Zuclopenthixol | cis-Clopenthixol,Cisordinol,(Z)-Clopenthixol | Dopamine Receptor |
Zuclopenthixol (cis-Clopenthixol) is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors. | |||
T67729 | UCM-1306 | Dopamine Receptor | |
UCM-1306 is a potent and orally active allosteric modulator (PAM) of human dopamine D1 receptor. UCM-1306 could increase the maximal effect of endogenous dopamine (DA) both in human and mouse D1 receptors. UCM-1306 could... | |||
T0074L | Chlorprothixene hydrochloride | NSC 78193,Minithixen,Truxal hydrochloride,NSC 56379,NSC 169899,Minithixen hydrochloride | Dopamine Receptor , 5-HT Receptor , Antibacterial , AChR , Histamine Receptor |
Chlorprothixene hydrochloride (Truxal hydrochloride) brings strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors. Chlorprothixene hydrochloride s a typical an... | |||
T60835 | SKF83959 | Dopamine Receptor | |
SKF83959, a benzazepine analog, is a selective and potent partial agonist of the dopamine D1 receptor with Ki values of 1.18, 7.56, 920, and 399 nM for rat D1, D5, D2, and D3 receptors, respectively.SKF83959 is a potent ... | |||
T22921 | LE 300 | Dopamine Receptor , 5-HT Receptor | |
dopamine D1 receptor antagonist | |||
T28167 | NGB 2904 | NGB2904 HCl,NGB-2904,NGB2904 | Others , Dopamine Receptor , 5-HT Receptor |
NGB 2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively). NGB2904 potently antag... | |||
T14767 | BP 897 hydrochloride | Dopamine Receptor | |
BP 897 is a potent and selective agonist of dopamine D3 receptor and it is a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 and D2 receptors. Which shows low affinities at D1 and D4 receptors ... | |||
T21446 | Rotigotine Hydrochloride | Rotigotine (Hydrochloride),N 0923,N-0924,Rotigotine HCl,N-0923 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
Rotigotine Hydrochloride (N-0924), a dopamine receptor agonist prefering for D3 receptors over D1 and D2, has effective activity of anti-Parkinsonian. Racemic rotigotine hydrochloride is about 50 times as potent as quinp... | |||
T23265 | RS 67333 hydrochloride | RS 67333 (hydrochloride),RS 67333 HCl | 5-HT Receptor |
RS 67333 hydrochloride (RO5203648) is a potent, selective partial agonist of the 5-HT4 receptor (5-HT4R) with a pKi value of 8.7 in guinea-pig striatum. It demonstrates lower binding affinities for other receptors, inclu... | |||
T9100 | BP 897 | 2-Naphthalenecarboxamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]- | Dopamine Receptor |
BP 897 (2-Naphthalenecarboxamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-) is a potent and selective dopamine D3 receptor agonist, and a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 ... | |||
T2592 | Ropinirole hydrochloride | SKF 101468 hydrochloride,SKF-101468A,Ropinirole HCl | Dopamine Receptor |
Ropinirole hydrochloride (SKF-101468A) is a selective dopamine D2 receptors agonist (Ki: 29 nM). Ropinirole hydrochloride (SKF-101468A) is the hydrochloride salt form of ropinirole, a non-ergot dopamine agonist with anti... | |||
T0162 | Quetiapine | ICI204636,Quetiapin | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR , Histamine Receptor |
Quetiapine (ICI204636) is used for the therapy of schizophrenia, and for the treatment of acute manic episodes associated with bipolar I disorder. The mechanism of quetiapine' action is thought by mediated through antago... | |||
T2546 | Pimozide | R6238 | Potassium Channel , Dopamine Receptor , Adrenergic Receptor , STAT |
Pimozide (R6238) is a diphenylbutylpiperidine derivative and a dopamine antagonist with the antipsychotic property. Pimozide selectively inhibits type 2 dopaminergic receptors in the central nervous system (CNS), thereby... | |||
T30603 | BT-Sch | ||
Bt-sch is an imaging agent based on D1 and D2 receptors of dopamine. | |||
T4117L2 | Zuclopenthixol dihydrochloride | ||
Zuclopenthixol dihydrochloride is an D1 and D2 dopamine receptors antagonist. | |||
T29213 | Zelandopam free base | YM-435,YM435,MYD-37,MYD37,Zelandopam | |
Zelandopam is a dopamine D1 agonist. Zelandopam is a potent stimulant of pancreatic exocrine secretion by acting on DA D1 receptors of the pancreas in dogs. Intravenous administration of Zelandopam produces renal vasodil... | |||
TQ0315 | Tandospirone | SM-3997 | 5-HT Receptor |
Tandospirone (SM-3997) is a selective partial agonist of 5-HT1A receptor (Ki: 27 nM) that displays selectivity over SR-2, SR-1C, α1, α2, D1 and D2 receptors (Kis: 1300-41000 nM). | |||
T68193 | Clopenthixol | ||
Clopenthixol is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors. | |||
T69103 | Clopenthixol decanoate | ||
Clopenthixol decanoate is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors. | |||
T68963 | Alpha-Clopenthixol dihydrochloride | ||
alpha-Clopenthixol dihydrochloride is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors. | |||
T35307 | Zicronapine | Lu-31130,Lu31-130,Lu 31130,Lu 31-130,Lu31130,Lu-31-130 | |
Zicronapine( LU 31-130) is an atypical antipsychotic. Zicronapine has monoaminergic activity and multi-receptor properties. It has shown effective antagonism against dopamine D1, D2, and serotonin 5HT2A receptors in vitr... | |||
T41014 | MLS1082 | ||
MLS1082 is a pyrimidone-derived compound that acts as a positive allosteric modulator of D1-like dopamine receptors. It exhibits an EC 50 value of 123 nM for stimulating G protein signaling in response to dopamine activa... | |||
T73823 | DETQ | ||
DETQ, a selective, allosteric, and orally active potentiator of the dopamine D1 receptor (Dopamine Receptor), enhances cAMP production in HEK293 cells expressing the human D1 receptor, achieving an EC50 of 5.8 nM and a K... | |||
T74668 | Zicronapine fumarate | ||
Zicronapine (Lu 31-130) fumarate, an antipsychotic medication, exhibits potent pro-cognitive effects in animal models and holds promise for treating various neurological and psychiatric conditions. It acts as a strong an... | |||
T60418 | Ropinirole | ||
Ropinirole (SKF 101468) is a selective D2-like family receptor agonist whereas it has no affinity for the D1 receptors. It is an orally active, potent D3/D2 receptor agonist with a Ki of 29 nM for D2 receptor, which als... | |||
T83776 | Dopamine D3 Receptor Agonist 13a | ||
Dopamine D3 receptor agonist 13a selectively targets the dopamine D3 receptor over dopamine D1, D2, and D4 receptors, with affinities (Ki values) of 0.14, 4,600, 2.85, and 756 nM, respectively. It also interacts with ser... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-04270 | GPR133 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
ADGRD1 (Adhesion G Protein-Coupled Receptor D1, also known as GPR133) is a Protein Coding gene. 4 alternatively spliced human isoforms have been reported. ADGRD1, an orphan member of the adhesion family of G-protein-coup... | |||
TMPY-00150 | IGF2/IGF-II Protein, Human, Recombinant | Human | P. pastoris (Yeast) |
Insulin-like growth factor 2 (IGF-2/IGF-II) is a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele,... |