|
T1076 |
Dexamethasone
|
MK 125,Prednisolone F,NSC 34521,Hexadecadrol |
Glucocorticoid Receptor
,
Mitophagy
,
IL Receptor
,
SARS-CoV
,
Antibacterial
,
Antibiotic
,
Autophagy
,
Complement System
|
|
Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist and an IL receptor modulator. Dexamethasone has anti-inflammatory and immunosuppressive activity and induces autophagy. Dexamethasone inhibits LPS-induced... |
|
T0947 |
Dexamethasone acetate
|
Dexamethasone 21-acetate,Dexamethason acetate,NSC 39471 |
Glucocorticoid Receptor
,
Mitophagy
,
IL Receptor
,
Annexin A
,
NOS
,
Antibacterial
,
Autophagy
|
|
Dexamethasone acetate (NSC 39471) is the acetate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexa... |
|
T15102 |
Dexamethasone palmitate
|
DXP |
Glucocorticoid Receptor
|
|
Dexamethasone palmitate (DXP), a lipophilic prodrug of Dexamethasone, shows a 47-fold lower affinity for the glucocorticoid receptor than Dexamethasone. Dexamethasone palmitate is a glucocorticoid receptor agonist and an... |
|
T0947L |
Dexamethasone Phosphate disodium
|
EGP-437,EGP437. Dex-Phos,EGP 437 |
Glucocorticoid Receptor
|
|
Dexamethasone Phosphate disodium (EGP437. Dex-Phos) is a water-soluble form of the synthetic glucocorticoid dexamethasone. |
|
T19277 |
Dexamethasone 9,11-epoxide
|
|
Others
|
|
Dexamethasone 9,11-epoxide is a compound obtained by extraction and is an intermediate in the preparation of dexamethasone. |
|
T6465 |
Dexamethasone Sodium Phosphate
|
Dexadreson,Dexagro,Dalalone |
IL Receptor
,
COX
|
|
Dexamethasone Sodium Phosphate (Dexadreson) , an interleukin receptor modulator, has anti-inflammatory and immunosuppressant effects. It belongs to a potent glucocorticoid class of steroid synthetic drugs. |
|
T21074 |
Dexamethasone acetate
|
Dexamethasone 21-acetate monohydrate,Decadron-LA,Decadron |
|
|
Dexamethasone acetate is an adrenocortical steroid. It is used in the treatment of many conditions, including rheumatic problems, a number of skin diseases, asthma, severe allergies, chronic obstructive lung disease, bra... |
|
T39088 |
Mc-Dexamethasone
|
|
|
|
Mc-Dexamethasone is a drug-linker conjugate for ADC . Mc-Dexamethasone is made toxin Dexamethasone conjugated to the non-cleavable MC linker. Dexamethasone is a glucocorticoid receptor agonist. |
|
T37361 |
6β-hydroxy Dexamethasone
|
|
|
|
6β-hydroxy Dexamethasone is a metabolite of dexamethasone that is more hydrophilic than the parent compound. Dexamethasone is metabolized by CYP3A4; therefore, quantification of the dexamethasone metabolites, 6α- and 6β-... |
|
T27152 |
Dexamethasone Beloxil
|
|
|
|
Dexamethasone Beloxil is a glucocorticoid, Anti-inflammatory Agent. |
|
T69323 |
Dexamethasone sodium succinate
|
|
|
|
Dexamethasone sodium succinate is the acetate salt form of dexamethasone, which is a synthetic glucocorticoid; it combines high anti-inflammatory effects with low mineralocorticoid activity. At high doses (e.g. 40 mg), i... |
|
T27153 |
Dexamethasone cipecilate
|
NS126,NS-126,NS 126 |
|
|
Dexamethasone cipecilate is a long-acting intranasal corticosteroid and a highly lipophilic anti-inflammatory corticosteroid. |
|
T23984 |
Dexamethasone phosphate
|
Neodecadron,EGP437,Hexadrol phosphate,EGP 437,EGP-437 |
|
|
Dexamethasone phosphate is a synthetic adrenal corticosteroid. It also has potent anti-inflammatory properties. |
|
T61525 |
Dexamethasone oxetanone
|
|
|
|
Dexamethasone oxetanone (Dex-Ox) is a glucocorticoid-selective derivative of Dexamethasone (Dex) compound. It acts as an antiglucocorticoid and an antiprogestin, demonstrating notable agonist activity with both PR A and ... |
|
T31395 |
Dexamethason 21-tert-butylacetate
|
Decadron TBA,Dexamethasone tert-butylacetate |
|
|
Dexamethason 21-tert-butylacetate is a biochemical. |
|
T2334 |
Avanafil
|
TA1790 |
PDE
|
|
Avanafil (TA1790) is a selective inhibitor of phosphodiesterase type 5 (PDE5) and is used as therapy of erectile dysfunction. |
|
T22818 |
GSK9027
|
GR agonist 23a,GSK 9027,GSK-9027 |
Glucocorticoid Receptor
|
|
GSK9027 (GR agonist 23a) is a nonsteroidal glucocorticoid receptor (GR) agonist.GSK9027 is a partial agonist on the 2×GRE reporter gene compared to dexamethasone and is less active than dexamethasone activity. |
|
T35386 |
Elotuzumab
|
Elotuzumab (anti-SLAMF7),BMS 901608,PDL 063,HuLuc 63 |
Others
|
|
Elotuzumab(HuLuc 63) is a monoclonal antibody that targets the SLAMF7 receptor.Elotuzumab is a compound that directly activates NK cells and induces antibody-dependent cytotoxicity, and can be used in combination with le... |
|
T38034 |
MAO-IN-M30 dihydrochloride
|
M 30 dihydrochloride |
Monoamine Oxidase
|
|
MAO-IN-M30 dihydrochloride (M 30 dihydrochloride) is a potent and brain selective monoamine oxidase (MAO) inhibitor (EC50 values are 37 and 57 nM for MAO-A and MAO-B, respectively). Also an iron chelator with antioxidant... |
|
T24189 |
J9
|
J-9,J 9 |
|
|
J9 is an inhibitor of Glucocorticoid resistance. J9 reverses Dexamethasone Resistance in T-cell Acute Lymphoblastic Leukemia. |
|
T27999 |
MDK-4624
|
AMPKα1 activator C13,C13, Compound 13 |
|
|
MDK-4624 is a AMPKα1 activator. MDK-4624 inhibits Helicobacter pylori-induced oxidative stresses and gastric epithelial cell apoptosis. MDK-4624 attenuates dexamethasone-induced osteoblast cell death. MDK-4624 potently i... |
|
T27790 |
Labradimil
|
RMP-7,ALK-01-040,Receptor-mediated permeabiliser-7,DRG0182,DRG 0182,DRG-0182 |
|
|
Labradimil is a bradykinin B2 receptor agonist. Labradimil increases the permeability of human brain microvascular endothelial cell monolayers. Labradimil enhances delivery of hydrophilic chemotherapeutics and increases ... |
|
T70904 |
Tylogenin
|
|
|
|
Tylogenin, a steroidal aglycone generated by acid hydrolysis from two seasonal glycosides occurring in Tylophora sylvatica, inhibits IgE-induced basophil mediator release for allergic reactions. In the rabbit basophil-de... |
|
T70346 |
TOP1362
|
|
|
|
TOP1362 is a Narrow Spectrum Kinase Inhibitors Demonstrate Promise for the Treatment of Dry Eye Disease and Other Ocular Inflammatory Disorders. TOP1362 strongly inhibited the kinase targets p38α, Syk, Src, and Lck, bloc... |
|
T68306 |
INCB16562
|
|
|
|
INCB16562 is a novel, selective, and orally bioavailable small-molecule inhibitor of JAK1 and JAK2 markedly selective over JAK3. Treatment of myeloma cells with INCB16562 potently inhibited interleukin-6 (IL-6)-induced p... |
