FMK | TargetMol

カタログ番号	製品名	別名	ターゲット
TQ0310	FMK		S6 Kinase
	FMK is an irreversible inhibitor of RSK2 kinase.		S6 Kinase
T7020	Z-VAD-FMK	Z-VAD(OH)-FMK,Caspase Inhibitor VI,Z-VAD	Caspase
	Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases with irreversible properties. Z-VAD-FMK binds to activated caspases, thereby inhibiting apoptosis.		Caspase
T6013	Z-VAD(OMe)-FMK	Z-VAD-FMK,Z-Val-Ala-Asp(OMe)-FMK	Caspase
	Z-VAD(OMe)-FMK (Z-Val-Ala-Asp(OMe)-FMK) is a broad-spectrum inhibitor of caspases that is cell-permeable and irreversible. Z-VAD(OMe)-FMK binds to activated caspases, thereby inhibiting apoptosis.		Caspase
T7019	Z-IETD-FMK	Z-IE(OMe)TD(OMe)-FMK,Caspase-8 Inhibitor	Caspase
	Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective caspase 8 inhibitor, which has cell permeable.		Caspase
T15303	FMK 9a		Cysteine Protease , Autophagy
	FMK 9a is an irreversible inhibitor of ATG4B with IC50 values of 80 and 73 nM in the TR-FRET and cellular-based LRA assays.		Cysteine Protease , Autophagy
T6005	Z-DEVD-FMK	Caspase-3 Inhibitor	Caspase
	Z-DEVD-FMK (Caspase-3 Inhibitor) is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7, caspase-8, and caspase-10.		Caspase
T21835	Z-LEHD-fmk		Apoptosis , Caspase
	Z-LEHD-FMK is a selective and potent caspase-9 inhibitor that protects against reperfusion injury and slows apoptosis.Z-LEHD-FMK exhibits antitumor and neuroprotective activity, increases the yield of in vitro-produced p...		Apoptosis , Caspase
TP1466	Z-YVAD-FMK		Caspase
	AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities.		Caspase
T6738	Z-FA-FMK		SARS-CoV , Cysteine Protease
	Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.		SARS-CoV , Cysteine Protease
T10580	BOC-D-FMK		Apoptosis , Caspase
	Boc-D-FMK is an irreversible, cell-permeable, and broad-spectrum caspase inhibitor and inhibits apoptosis stimulated by TNF-α (IC50: 39 µM).		Apoptosis , Caspase
T36331	Z-AEVD-FMK	Z-AEVD-FMK,Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone
	Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases.[1] At 10 &#181M, it can prevent the initiation of Fas signaling by caspase-10 in Jurkat T lymphoma cells, preventing Bid cleavage into its activ...
T11310	FMK-MEA		Others
			Others
T39344	Z-VDVA-(DL-Asp)-FMK
	Z-VDVA-(DL-Asp)-FMK is a derivative compound of Z-VDVAD-FMK specifically designed as an inhibitor targeting caspase-2.
T10548	Biotin-VAD-FMK		Caspase
	Biotin-VAD-FMK is a cell-permeable, irreversible biotin-labeled inhibitor of caspase. It is used to identify active caspases in cell lysates.		Caspase
TP2161	Z-WEHD-FMK		Caspase
	Z-WEHD-FMK is a cell-permeable and irreversible inhibitor of caspase-1/5. It also shows a robust inhibitory effect on cathepsin B activity (IC50: 6 μM).		Caspase
T40602	Z-LEHD-FMK TFA
	Z-LEHD-FMK TFA is a specific and irreversible inhibitor of caspase-9, offering protection against detrimental reperfusion injury and moderating apoptosis. Additionally, Z-LEHD-FMK TFA demonstrates its neuroprotective pot...
TP1014	Z-VRPR-FMK (TFA)	VRPR
	Z-VRPR-FMK (TFA) (VRPR) is a tetrapeptide and a selective and irreversible inhibitor of lymphoma translocation protein 1 (MALT1) in mucosa-associated lymphoid tissue.
T23555	Z-VEID-FMK		Others
	When compared to other caspase inhibitors, Z-DRHD-FMK inhibited caspase 6 activity more effectively than the general caspase inhibitor of Z-Val-Ala-Asp (OMe)-fluoromethy ketone (Z-VAD-FMK) or the caspase 6 inhibitor Z-V...		Others
TP2037	Z-DQMD-FMK
	Caspase-3 inhibitor. Inhibits MG 132-induced small cell lung cancer cell death in vitro.
T38469	(Rac)-Z-Phe-Phe-FMK	Cathepsin L-IN-2	Beta Amyloid , Cysteine Protease
	(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .		Beta Amyloid , Cysteine Protease
T78186	Ac-VLPE-FMK	Ac-Val-Leu-Pro-Glu(OMe)-CH2F
	Ac-VLPE-FMK, a tetrapeptidyl mono-fluoromethyl ketone (m-FMK), functions as an inhibitor of both Cathepsin B (Cat-B) and Cathepsin L (Cat-L), and is utilized in research pertaining to the aggressiveness of cancer [1] [2]...
T78185	Ac-PLVE-FMK	Ac-Pro-Leu-Val-Glu(OMe)-CH2F	Others
	Ac-PLVE-FMK (Ac-Pro-Leu-Val-Glu(OMe)-CH2F), a tetrapeptidyl fluoromethylketone (FMKs), serves as a cathepsin inhibitor. It is utilized in cancer research [1].		Others
T39308	Boc-Asp(OMe)-fluoromethyl ketone	Boc-Asp(OMe)-fluoromethyl ketone,Boc-Asp(OMe)-FMK	Caspase
	Boc-Asp(OMe)-fluoromethyl ketone (Boc-Asp(OMe)-FMK) is a broad range caspase inhibitor. Boc-Asp(OME)-Fluoromethyl Ketone inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemot...		Caspase
TP2101	Z-VRPR-FMK trifluoroacetate salt
	Irreversible MALT1 inhibitor. Suppresses T cell activation-induced cleavage of Bcl-10 in a dose-dependent manor. Reduces Jurkat cell adhesion to fibronectin. Cell permeable.
T71586	Z-VAE(OMe)-fmk
	Z-VAE(OMe)-fmk is a cell-permeable and irreversible UCHL1 inhibitor. The inhibitor approaches the active-site cleft from the opposite side of the crossover loop as compared to the direction of approach of ubiquitin's C-t...
T76665	Z-LEED-FMK
	Z-LEED-FMK is a chemical compound that acts as an inhibitor for caspase-13 and caspase-4. Additionally, it impedes caspase-1 processing in S. typhimurium-infected macrophages [1] [2].
T80542	Z-Leu-Leu-Leu-fluoromethyl ketone	Z-LLL-FMK
	Z-Leu-Leu-Leu-fluoromethyl ketone (Z-LLL-FMK) functions as a cysteine protease inhibitor and has been shown to impede SARS infection. Furthermore, it affords protection to mice when challenged with T. crassiceps [1] [2].
T73096	Z-LEVD-FMK
	Z-LEVD-FMK, a cell-permeable caspase-4 inhibitor, effectively blocks endoplasmic reticulum (ER) stress-induced apoptosis in cancer cells.
T73093	Z-VRPR-FMK
	Z-VRPR-FMK, an irreversible inhibitor of the MALT1 protein, effectively suppresses the proliferation and invasion of diffuse large B-cell lymphoma. This is achieved through the inhibition of MALT1-induced NF-κB activatio...
T78632	Z-LLY-FMK	Calpain Inhibitor IV	Proteasome
	Z-LLY-FMK (Calpain Inhibitor IV) serves as an inhibitor of calpain, a family of proteases implicated in the apoptosis of various cell systems. Specifically, this compound suppresses intestinal cell apoptosis following co...		Proteasome
T80551	Calpain inhibitor V	Mu-Val-HPh-FMK	Antibiotic
	Calpain Inhibitor V (Mu-Val-HPh-FMK) is a cell-permeable, irreversible calpain inhibitor with demonstrated anti-chlamydial activity [1].		Antibiotic
T75938	Z-VRPR-FMK TFA
	Z-VRPR-FMK (TFA), a selective and irreversible inhibitor of Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1), is a tetrapeptide shown to provide protection against influenza A virus (IAV) infect...
T83963	Z-DEVD-FMK Caspase-3 Inhibitor
	Z-DEVD-FMK, a Caspase-3 Inhibitor, is an irreversible, cell-permeable inhibitor of caspase-3/CPP32 that impedes tumor cell apoptosis. In vivo studies show it offers neuroprotection in rat hippocampi post-seizures and con...
T72435	Z-LE(OMe)TD(OMe)-FMK
	Z-LE(OMe)TD(OMe)-FMK is a selective inhibitor of caspase-8, effectively inhibiting cellular apoptosis.
T71584	Microtubule Inhibitor 185322
	Microtubule inhibitor 185322 is an inhibitor of microtubule assembly, inducung mitotic arrest and apoptosis of MM cells.
T41345	AFMK	Formyl-N-acetyl-5-methoxykynurenamine,Acetyl-N-formyl-5-methoxykynurenamine	Apoptosis , Free radical scavengers , Antioxidant , Endogenous Metabolite
	AFMK (Formyl-N-acetyl-5-methoxykynurenamine) is an active metabolite of Melatonin with antioxidant and free radical scavenging activity. AFMK is a modulator of apoptosis and improves the anti-tumor effect of Gemcitabine ...
T10845	CMK		Others
	CMK, an RSK2 kinase inhibitor, shows similar potency but less chemical stability compared with FMK.		Others
T69200	CGP74514A
	CGP74514A is a CDK1 inhibitor with potential anticancer activity. In U937 cells, CGP74514A - induced apoptosis (5 microM) became apparent within 4 hr and approached 100% by 24 hr. The pan- caspase inhibitor Boc-fmk and t...