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Search Results for " LOXIN "

ターゲット

15

阻害剤

3

天然化合物

2

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T16703 Quarfloxin CX-3543 DNA/RNA Synthesis
Quarfloxin (CX-3543) is a fluoroquinolone derivative with antineoplastic activity with IC50 values in the nanomolar range in neuroblastoma cells. Quarfloxin disrupts the interaction between the nucleolin protein and a G-...
T22456 Voreloxin hydrochloride SNS-595 hydrochloride,Vosaroxin Apoptosis , Topoisomerase
Voreloxin hydrochloride (SNS-595 hydrochloride) is a potent inhibitor of Topoisomerase II with broad-spectrum anti-tumor activity.
T40437L Caloxin 2A1 acetate Proton pump
Caloxin 2A1 acetate is an inhibitor of extracellular plasma membrane Ca2+-ATPase (PMCA) peptide. Caloxin 2A1 acetate inhibits Ca2+-dependent formation of the 140-kDa acid-stable acylphosphate.
T63540 Astrophloxine Beta Amyloid
Astrophloxine is a fluorescent imaging probe capable of targeting antiparallel dimers.Astrophloxine can be used to detect aggregated Aβ in brain tissue and cerebrospinal fluid samples from Alzheimer's disease (AD) mice.
T25969 Poloxin-2 Poloxin2,Poloxin 2 PLK
Poloxin-2 is a potent and selective Plk1 PBD inhibitor with anti-tumour activity that reduces the protein level of Plk1 in HeLa cells.
T16560 Poloxin PLK
Poloxin is a non-ATP competitive Polo-like Kinase 1 inhibitor. It targets the polo-box domain (IC50: appr 4.8 μM).
T123923 Altiloxin B
Altiloxin B is a useful organic compound for research related to life sciences. The catalog number is T123923 and the CAS number is 92675-14-4.
T82789 Caloxin 1B1
Caloxin 1B1, a bioactive peptide, exhibits selective inhibition of PMCA extracellularly by binding preferentially to the extracellular domain 1 of PMCA4 over PMCA1. Identified through a screening process for its high-aff...
T37756 Phloxine B
Phloxine B is a red dye, the USP grade of which is used as a color additive for food, drugs, and cosmetics. It has also been used as an alternative to Gram staining, to differentiate between Gram-negative and Gram-positi...
T40471 Azophloxine Acid red 1,Azophloxine
Azophloxine, also known as acid red 1 (AR1), is a member of synthetic red azo dye family.
T35923 Caloxin 2A1 TFA
Caloxin 2A1 TFA is a peptide inhibitor specifically targeting the extracellular plasma membrane Ca2+-ATPase (PMCA), without influencing the basal activities of Mg2+-ATPase or Na+-K+-ATPase[1].
T80247 Caloxin 3A1 Calcium Channel
Caloxin 3A1, a biologically active peptide, is a member of the caloxins, which are inhibitors of the extracellular plasma membrane (PM) Ca2+ pumps. Specifically, it inhibits plasma membrane calcium pumps (PMCAs) without ...
T6724 Voreloxin Vosaroxin,AG 7352,SNS-595 Apoptosis , Topoisomerase
Voreloxin (SNS-595) is a potent Topoisomerase II inhibitor with broad-spectrum anti-tumor activity. Phase 2.
T40437 Caloxin 2A1
Caloxin 2A1 is an inhibitor peptide of the plasma membrane Ca 2+-ATPase (PMCA) responsible for extracellular signaling. Importantly, Caloxin 2A1 has no impact on the basal Mg 2+-ATPase or Na+-K+-ATPase activities.
T34715 Stemphyloxin I Deacyl-FR 225654
Stemphyloxin I is a phytotoxin from Stemphylium botryosum.
カタログ番号 製品名 別名 ターゲット
TN4752 Perilloxin COX
Perilloxin possesses inhibitory activities against cyclooxygenase-1,with IC(50) values of 23.2 microM.
TN3810 Dehydroperilloxin COX
Dehydroperilloxin possesses inhibitory activity against cyclooxygenase-1, with the IC(50) value of 30.4 microM.
TN2938 3-Hydroxy-3-acetonyloxindole Others
3-Hydroxy-3-acetonyloxindole is a natural product of Marsdenia, Asclepiadaceae. The catalog number is TN2938 and the CAS number is 33417-17-3. 3-Hydroxy-3-acetonyloxindole can be used as a reference standard.

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-02490 LOX-1 Protein, Human, Recombinant (His) Human HEK293 Cells
LOX-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is P78380.
TMPK-01168 LOX-1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
LOX-1 is a transmembrane glycoprotein that binds to and internalizes ox-LDL.LOX-1 gene deletion in mice and anti-LOX-1 therapy has been shown to decrease inflammation, oxidative stress and atherosclerosis. LOX-1 deletion...