|
T10860 |
Col003
|
|
HSP
|
|
Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding site on Hsp47 (IC50: 1.8 μM). It can be used for the investigation of fibrosis. |
|
T38155 |
N-Acetyl-D-cysteine
|
|
Reactive Oxygen Species
|
|
N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group. |
|
T3266 |
Lumefantrine
|
Benflumetol,dl-Benflumelol |
Others
,
Parasite
,
Autophagy
|
|
Lumefantrine (dl-Benflumelol) is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with artemether for improved efficacy. This combination therapy exerts its effects again... |
|
T33272 |
Mefenidil
|
McN-2378,McN 2378 |
Others
|
|
Mefenidil (McN-2378), a selective cerebral vasodilator, was shown to increase CBF in healthy brains without stimulating O2 uptake in a dog anesthesia model. |
|
T7593 |
Levomefolate calcium
|
|
Antifolate
|
|
Levomefolate calcium is an artificial form of folate. It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements. |
|
T0273 |
Mefexamide
|
Mefaxadyne,Timodyne,Mefexamide hydrochloride |
Others
|
|
Mefexamide hydrochloride is a central stimulant. |
|
T11991 |
Mefentrifluconazole
|
|
P450
,
Antifungal
|
|
Mefentrifluconazole is a potent, selective and orally active fungal CYP51 (Kd= 0.5 nM) inhibitor, but shows less inhibitory activity on human aromatase (IC50=0.92 μM). Mefentrifluconazole is a novel azole derivative and ... |
|
T7726 |
Triadimefon
|
|
Antifungal
|
|
Triadimefon is an azole fungicide used to control powdery mildew. |
|
T0860 |
Mefloquine hydrochloride
|
Mefloquin hydrochloride,Mefloquine HCl |
Potassium Channel
,
SARS-CoV
,
Reactive Oxygen Species
,
Parasite
,
Autophagy
|
|
Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria. |
|
T1625 |
Lomefloxacin hydrochloride
|
Lomefloxacin HCl,Okacyn,Maxaquin |
Topoisomerase
,
Antibacterial
,
Antibiotic
|
|
Lomefloxacin hydrochloride (Okacyn) inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during... |
|
T0890 |
Mefenamic acid
|
CN-35355,CI 473 |
COX
|
|
Mefenamic acid (CN-35355) is a non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase. |
|
T1444 |
Lomefloxacin
|
SC47111A |
Topoisomerase
,
Antibacterial
,
Antibiotic
|
|
Lomefloxacin (SC47111A) is a synthetic broad-spectrum fluoroquinolone with antibacterial activity. |
|
T0860L |
Mefloquine
|
Ro215998,WR 142490,Ro-215998,Lariam,Ro 215998 |
Others
|
|
Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine can be used for malaria, systemic l... |
|
T33274 |
Mefeserpine
|
Mefeserpinum,Mefeserpina |
|
|
Mefeserpine is a biochemical. |
|
T20971 |
Mefluidide
|
VEL3973,VEL-3973,VEL 3973,MBR 12325 |
|
|
Mefluidide is a biochemical. |
|
T21110 |
Mefenacet
|
|
|
|
Mefenacet is an herbicide for rice. |
|
T7593L |
Levomefolate sodium
|
L 5 MTHF sodium,L-5-MTHF sodium,L5MTHF sodium, |
|
|
Levomefolate calcium is a primary biologically active form of folate used at the cellular level for dna reproduction, the cysteine cycle and the regulation of homocysteine |
|
T10999 |
Desbutyl Lumefantrine
|
Desbutyl-benflumetol |
Others
|
|
Desbutyl Lumefantrine is a metabolite of lumefantrine with antimalarial activity. |
|
T33275 |
Mefox
|
(6RS)-Mefox |
|
|
Mefox is a bioactive chemical. |
|
T31484 |
Dimefuron
|
Pradone plus,Pradone TS,RP 23465,Vt 2809,Pradone kombi |
Others
|
|
Dimefuron (Vt 2809) is a chemical compound from the group of phenylureas used as a herbicide or insecticide. |
|
TMIH-0325 |
MefenaMic Acid-d4
|
|
|
|
MefenaMic Acid-d4 is a deuterated compound of MefenaMic Acid. MefenaMic Acid has a CAS number of 61-68-7. Mefenamic acid is a non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic prope... |
|
T21352 |
Salmefamol
|
AHR-3929,AHR3929,AHR 3929 |
|
|
Salmefamol is a beta-adrenergic agonist. It may also be used as a bronchodilator. |
|
T75689 |
Mumefural
|
|
|
|
Mumefural, a bioactive compound found in the processed fruit of Prunus mume Sieb., inhibits platelet aggregation, exhibits anti-thrombotic properties, and ameliorates cognitive impairment [1] [2]. |
|
T33277 |
Mefway F-18
|
18F-Mefway |
|
|
Mefway F-18 is a PET radioligand specific to serotonin-1A receptors. |
|
T38763 |
Mefenpyr-diethyl
|
|
|
|
Mefenpyr-diethyl is an herbicide safener, which protects crops against herbicide injury. |
|
T33276 |
Mefruside
|
FDA1902,FDA-1902,FDA 1902,FBA-1500,FBA1500,FBA 1500 |
|
|
Mefruside is a diuretic indicated for the treatment of edema and hypertension. |
|
T29314 |
Lumefantrine Impurity A
|
2-(Dibutylamino)-2-(2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl)ethanol, (RS, Z)- |
|
|
2-(Dibutylamino)-2-(2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl)ethanol, (RS, Z)- is a bioactive chemical. |
|
T32706 |
Levomefolate calcium pentahydrate
|
|
|
|
Levomefolate calcium pentahydrate is the calcium salt of 5-methyltetrahydrofolic acid, a biologically active form of folic acid that functions, in conjunction with Vitamin B12. Levomefolate is included in formulations of... |
|
T31374 |
Demethylchlordimeform
|
Demethylchlorphenamidine |
|
|
Demethylchlordimeform is a biochemiacl. |
|
TMIH-0305 |
Lomefloxacin-d5 hydrochloride
|
|
|
|
Lomefloxacin-d5 hydrochloride is a deuterated compound of Lomefloxacin hydrochloride. Lomefloxacin hydrochloride has a CAS number of 98079-51-7. Lomefloxacin is a synthetic broad-spectrum fluoroquinolone with antibacteri... |
|
T11891 |
Lumefantrine-d18
|
Benflumetol D18,Lumefantrine D18 |
Others
|
|
Lumefantrine D18 is an antimalarial drug, and is the deuterium labeled Lumefantrine. |
|
T19275 |
Desbutyl Lumefantrine D9
|
Desbutyl-benflumetol D9 |
Others
|
|
Desbutyl Lumefantrine D9, a deuterium-labeled metabolite of Lumefantrine, exhibits the incorporation of deuterium atoms. |
|
T32705 |
Levomefolate magnesium
|
L-Methylfolate magnesium |
|
|
Levomefolate magnesium is the magnesium salt of the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human ... |
|
T11992 |
Mefuparib hydrochloride
|
MPH |
PARP
|
|
Mefuparib hydrochloride induces apoptosis and possesses prominent anticancer activity in vitro and in vivo. Mefuparib hydrochloride (MPH) is an orally active, substrate-competitive and selective PARP1/2 inhibitor with IC... |
|
T63214 |
Lomefloxacin (aspartate)
|
|
|
|
Lomefloxacin (SC47111A) aspartate is a broad-spectrum quinolone antibacterial agent that can be used in the study of respiratory tract infections, gastrointestinal infections, genitourinary infections, and ear, nose, and... |
|
T70785 |
Mefuparib Free Base
|
|
|
|
Mefuparib Free Base is a potent, highly selective, competitive PARP1/2 inhibitor with IC50 of 3.2/1.9 nM, respectively. Mefuparib (CVL218), has been shown to have promising antiviral activity against the virus that cause... |
|
TMIH-0306 |
Lomefloxacin-d5
|
|
|
|
Lomefloxacin-d5 is a deuterated compound of Lomefloxacin. |
|
T27401 |
Garomefrine HCl
|
PNO-49B,NS-49,ABT-232,ABT232,NS49,PNO49B |
|
|
Garomefrine HCl, a α1A-adrenoceptor agonist, is potential for the treatment of urinary incontinence. |
|
T36935 |
PKUMDL-LC-101-D04
|
GPX4-Activator-1d4,PKUMDL-LC-101-D04 |
GPX
|
|
PKUMDL-LC-101-D04 is a potent allosteric activator of glutathione peroxidase 4 (GPX4), a regulator of iron death. GPX4 activity was increased to 150% of control levels when used at a concentration of 20 μM in a cell-free... |
|
T78170 |
Kras4B G12D-IN-1
|
|
Ras
|
|
Kras4B G12D-IN-1 is an anticancer agent that functions as an inhibitor of the Kras4B G12D protein. It effectively reduces the expression of Kras protein in mouse embryonic fibroblasts (MEFs) harboring the Kras4B G12D mut... |
|
T82108 |
ICMT-IN-35
|
|
|
|
ICMT-IN-35 (compound 10n), an ICMT inhibitor with an IC50 value of 0.8 μM, is a FTPA-triazole derivative. It demonstrates cellular uptake by mammalian cells, disrupts K-Ras membrane association, and induces K-Ras misloca... |
|
T69403 |
AZD-3409
|
|
|
|
AZD-3409 is a potent prenyl transferase inhibitor. AZD-3409 showed higher potency than lonafarnib. The mean IC(50) for cytotoxicity of AZD3409 was 510 in MEF cells, 10,600 in A549 cells and 6,170 in MCF7 cells, respectiv... |
|
T69195 |
UC-857993
|
|
|
|
UC-857993, a selective SOS1-Ras inhibitor (Kd=14.7 μM, His6-SOS1cat), effectively suppresses catalytic activity. In addition to inhibiting ERK and Ras activation, it also hampers the growth of mouse embryonic fibroblasts... |
