ペプチド
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色素試薬
PROTAC
バーチャルスクリーニング
TargetMolキット
Cell Counting Kit-8 (CCK-8)
Inhibitor Cocktails
天然化合物
フェノール類
アルカロイド類
フラボノイド類
阻害剤
血管新生
アポトーシス
オートファジー
細胞周期・チェックポイント
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細胞骨格シグナル
DNA損傷・DNA修復
内分泌・ホルモン
GPCR/Gタンパク質
免疫・炎症
JAK・STATシグナル
| Cat. No. | 製品名 | CAS No. | Purity | Chemical Structure |
|---|---|---|---|---|
| T1776L | Plerixafor octahydrochloride | 155148-31-5 | 98% |
|
| AMD 3100 octahydrochloride blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4, resulting in hematopoietic stem cell (H... | ||||
| T22565 | AMD-070 hydrochloride | 880549-30-4 | 98% |
|
| AMD-070 hydrochloride is a CXCR4 antagonist, is useful for Anti HIV. | ||||
| TP1364L | ALX 40-4C acetate | TP1364L | 98% |
|
| ALX 40-4C acetate is a CXCR4 inhibitor of the chemokine receptor (Ki = 1 μM) and suppresses the replication of X4 strains of HIV-1. ALX 40-4C acetate is an antag... | ||||
| TP2051L | CTCE 9908 acetate | 98% |
|
|
| CTCE 9908 acetate is an antagonist of CXCR4 and inhibits migration in CXCR4-expressing ovarian cancer cells. | ||||
| TQ0174 | Mavorixafor | 558447-26-0 | 98% |
|
| Mavorixafor is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding. Mavorixafor inhibits the replication o... | ||||
| T9721 | ML339 | 2579689-83-9 | 98% |
|
| ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4. | ||||
| T5849 | JMS-17-2 | 1380392-05-1 | 98% |
|
| JMS-17-2 is a potent and selective antagonist of CX3CR1( IC50 : 0.32 nM). | ||||
| T1776 | Plerixafor | 110078-46-1 | 98% |
|
| Plerixafor, a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4. | ||||
| T14665L | Motixafortide TFA(664334-36-5,Free) | T14665L | 98% |
|
| Motixafortide is an antagonist of CXCR4 with IC50 of ～1 nM. It induces the apoptosis of AML blasts by down-regulating ERK, BCL-2, MCL-1 and cyclin-D1 via altered... | ||||
| T1955 | SB225002 | 182498-32-4 | 98% |
|
| SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2. | ||||
| T3992 | MSX-122 | 897657-95-3 | 98% |
|
| MSX-122 is a novel small molecule and partial CXCR4 antagonist, with potent inhibition of CXCR4/CXCL12 actions(IC50 = 10 nM). | ||||
| T6764L | ATI-2341 acetate(1337878-62-2 free base) | T6764L | 98% |
|
| ATI-2341 acetate is an effective allosteric agonist of CXCR4, it activates Gα1 instead of Gα13. ATI-2341 acetate activates inhibitory heterotrimeric G protein (G... | ||||
| T12705 | Reparixin L-lysine salt | 266359-93-7 | 98% |
|
| Reparixin L-lysine salt is an allosteric chemokine receptor 1/2 (CXCR1/2) activation inhibitor. | ||||
| T15805L | LY2510924 acetate(1088715-84-7 free base) | T15805L | 98% |
|
| Ly2510924 acetate is an potent and selective CXCR4 antagonist. It prevents the binding of SDF-1 to CXCR4 with an IC50 of 0.079 nM. | ||||
| T16850 | SB-265610 | 211096-49-0 | 98% |
|
| SB-265610 is a nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilizati... | ||||
| T26035 | Rac-NBI-74330 | 473722-68-8 | 98% |
|
| rac-NBI-74330 is an effective and selective CXCR3 antagonist. | ||||
| T4163 | Reparixin | 266359-83-5 | 98% |
|
| Reparixin is a potent inhibitor of both CXCL8 receptors CXCR1/2, it inhibits weakly CXCR2-mediated cell migration (IC50=100 nM), whereas it strongly blocks CXCR1... | ||||
| T7130 | Navarixin | 473727-83-2 | 98% |
|
| Navarixin(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation and modulates neutrophil trafficking in... | ||||
| T5193 | Danirixin | 954126-98-8 | 98% |
|
| Danirixin is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 nM). | ||||
| T11693L | IT1t dihydrochloride | 1092776-63-0 | 98% |
|
| IT1t dihydrochloride inhibits CXCL12/CXCR4 interaction with IC50 of 2.1 nM. IT1t dihydrochloride is an antagonist of CXCR4. | ||||
