| TP1364L |
ALX 40-4C acetate
|
TP1364L
|
98%
|
|
|
ALX 40-4C acetate is a CXCR4 inhibitor of the chemokine receptor (Ki = 1 μM) and suppresses the replication of X4 strains of HIV-1. ALX 40-4C acetate is an antag...
|
| TP2051L |
CTCE 9908 acetate
|
|
98%
|
|
|
CTCE 9908 acetate is an antagonist of CXCR4 and inhibits migration in CXCR4-expressing ovarian cancer cells.
|
| T76794 |
Ulocuplumab
|
1375830-34-4
|
98%
|
Ulocuplumab
|
|
Ulocuplumab (BMS-936564) is a fully human anti-CXCR4 IgG4 antibody.Ulocplumab exhibits antitumor activity in acute myeloid leukemia (AML), non-Hodgkin's lymphoma...
|
| T76782 |
Mogamulizumab
|
1159266-37-1
|
98%
|
Mogamulizumab
|
|
Mogamulizumab (KW-0761) is a monoclonal antibody against T cell CC chemokine receptor 4. Mogamulizumab has anticancer activity, eliminating tumor cells through a...
|
| T76741 |
Eldelumab
|
946414-98-8
|
98%
|
|
|
Eldelumab (BMS-936557) is a humanized anti-IP-10 IgG type 1 monoclonal antibody with inhibitory activity against CXCL10.Eldelumab has anti-inflammatory activity ...
|
| TQ0174 |
Mavorixafor
|
558447-26-0
|
98%
|
|
|
Mavorixafor (AMD-070) is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding. Mavorixafor inhibits the rep...
|
| T9721 |
ML339
|
2579689-83-9
|
98%
|
|
|
ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4.
|
| T5849 |
JMS-17-2
|
1380392-05-1
|
|
|
|
JMS-17-2 is a potent and selective antagonist of CX3CR1( IC50 : 0.32 nM).
|
| T1776L |
Plerixafor octahydrochloride
|
155148-31-5
|
|
|
|
Plerixafor octahydrochloride (JM3100 octahydrochloride) blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4, resulting ...
|
| TP2112L |
TC14012 acetate
|
TP2112L
|
|
|
|
TC14012 acetate is a serum-stable derivative of T140 which is a selective and peptidomimetic CXCR4 antagonist with an IC50 of 19.3 nM. TC14012 is also a potent C...
|
| T1776 |
Plerixafor
|
110078-46-1
|
100%
|
|
|
Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4.
|
| T14665L |
Motixafortide TFA(664334-36-5,Free)
|
T14665L
|
100%
|
|
|
Motixafortide TFA(664334-36-5,Free) (BKT140 TFA) is an antagonist of CXCR4 with IC50 of ～1 nM. It induces the apoptosis of AML blasts by down-regulating ERK, BCL...
|
| T11179 |
Elubrixin
|
688763-64-6
|
100.00%
|
|
|
Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin can be used for inflammatory disea...
|
| T1955 |
SB225002
|
182498-32-4
|
96.86%
|
|
|
SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2.
|
| T3992 |
MSX-122
|
897657-95-3
|
97.02%
|
|
|
MSX-122 is a novel small molecule and partial CXCR4 antagonist, with potent inhibition of CXCR4/CXCL12 actions(IC50 = 10 nM).
|
| T6764L |
ATI-2341 acetate(1337878-62-2 free base)
|
T6764L
|
97.14%
|
|
|
ATI-2341 acetate is an effective allosteric agonist of CXCR4, it activates Gα1 instead of Gα13. ATI-2341 acetate activates inhibitory heterotrimeric G protein (G...
|
| T12705 |
Reparixin L-lysine salt
|
266359-93-7
|
97.31%
|
|
|
Reparixin L-lysine salt (Repertaxin L-lysine salt) is an allosteric chemokine receptor 1/2 (CXCR1/2) activation inhibitor.
|
| T15805L |
LY2510924 acetate(1088715-84-7 free base)
|
T15805L
|
97.32%
|
|
|
Ly2510924 acetate is an potent and selective CXCR4 antagonist. It prevents the binding of SDF-1 to CXCR4 with an IC50 of 0.079 nM.
|
| T16850 |
SB-265610
|
211096-49-0
|
97.67%
|
|
|
SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calciu...
|
| T26035 |
Rac-NBI-74330
|
473722-68-8
|
97.85%
|
|
|
rac-NBI-74330 is an effective and selective CXCR3 antagonist.
|
