| TMPJ-00271
|
SMAD3 Protein, Human, Recombinant (His & Flag)
|
Human |
E. coli |
|
Mothers against decapentaplegic homolog 3(SMAD3) is a cytoplasm protein which belongs to the dwarfin/SMAD family. Smad proteins undergo rapid nuclear translocation upon stimulation by transforming growth factor and in so... |
| TMPH-01700
|
SMAD3 Protein, Human, Recombinant (His)
|
Human |
Baculovirus |
|
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in t... |
| TMPY-03419
|
SMAD3 Protein, Human, Mouse, Rat, Recombinant (His & GST)
|
Human,Mouse,Rat |
Baculovirus-Insect Cells |
|
SMAD3 belongs to the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD3 is... |
| TMPY-00413
|
TGF beta 2 Protein, Mouse, Recombinant (His)
|
Mouse |
HEK293 |
|
TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a... |
| TMPY-00835
|
IGFBP-3 Protein, Human, Recombinant (His)
|
Human |
HEK293 |
|
The Insulin-like Growth Factor (IGF) signaling system plays a central role in cellular growth, differentiation, and proliferation. IGFBP3 is the most abundant IGF binding protein in human serum and is a growth inhibitory... |
| TMPH-01359
|
CCND1 Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylat... |
| TMPH-02866
|
RBBP9 Protein, Mouse, Recombinant (His)
|
Mouse |
Yeast |
|
Serine hydrolase whose substrates have not been identified yet. May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation. May play a role in the transformation process due ... |
| TMPJ-00936
|
CCND2 Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
CCND2，also known as G1/S-specific cyclin-D2，is a member of the highly conserved cyclin family. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each ... |
| TMPH-01349
|
FOXL2 Protein, Human, Recombinant (His & Myc)
|
Human |
E. coli |
|
Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis th... |
| TMPY-04203
|
RAB1B Protein, Human, Recombinant (hFc)
|
Human |
HEK293 |
|
RAB1B, a member of the RAS oncogene family, was significantly down-regulated in highly metastatic breast cancer cells. Moreover, down-regulation of RAB1B was also found to promote the proliferation and migration of TNBC ... |
| TMPY-02444
|
ATF2 Protein, Human, Recombinant (His & GST)
|
Human |
Baculovirus-Insect Cells |
|
Activating transcription factor 2, also known as ATF2, is a member of the leucine zipper family of DNA-binding proteins that binds to the cAMP response element. Its activity is enhanced after phosphorylation by stress-ac... |
| TMPJ-01108
|
SMAD4 Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
SMAD Family Member 4 (SMAD4) is a cytoplasmic protein that belongs to the Dwarfin/SMAD family. SMAD4 contains one MH1 (MAD homology 1) domain and one MH2 (MAD homology 2) domain. It is the component of the heterotrimeric... |
| TMPH-01269
|
SMURF2 Protein, Human, Recombinant (His)
|
Human |
E. coli |
|
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Interacts with SMAD7 to trigger SMA... |
| TMPY-04577
|
TGF beta 2 Protein, Rhesus, Recombinant (His)
|
Rhesus |
HEK293 |
|
TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a... |
| TMPY-00231
|
TGF beta 2 Protein, Canine, Recombinant (His)
|
Canine |
HEK293 |
|
TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a... |
| TMPY-05314
|
TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated
|
Mouse |
HEK293 |
|
TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, a... |
| TMPY-03861
|
Amelotin Protein, Human, Recombinant (mFc)
|
Human |
HEK293 |
|
Amelotin (AMTN) is a tooth enamel protein which is expressed in maturation-stage ameloblasts and also in the internal basal lamina of junctional epithelium, a unique epithelial structure attached to the tooth surface whi... |
| TMPY-04422
|
Casein Kinase 1 gamma 2 Protein, Human, Recombinant (His)
|
Human |
Baculovirus-Insect Cells |
|
Casein kinase I gamma 2 isoform (CSNK1G2), a member of the large casein kinase I (CKI) subfamily, protein kinase superfamily. It may affect the development of brain, and associate with vesicular trafficking and neurotran... |
| TMPJ-01178
|
TGFBR1 Protein, Mouse, Recombinant (hFc)
|
Mouse |
Human Cells |
|
TGF-beta RI, also called ALK-5, is an approximately 55 kDa type I transmembrane serine/threonine receptor kinase. In the presence of TGF-beta, TGF-beta RI forms a complex with, and is phosphorylated by, TGF-beta RII. Pho... |
| TMPY-03251
|
IGFBP-3 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus |
HEK293 |
|
The Insulin-like Growth Factor (IGF) signaling system plays a central role in cellular growth, differentiation, and proliferation. IGFBP3 is the most abundant IGF binding protein in human serum and is a growth inhibitory... |
| TMPH-03764
|
YAP1 Protein, Human, Recombinant (His)
|
Human |
Yeast |
|
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor su... |
| TMPY-04468
|
STK16 Protein, Human, Recombinant (His & NusA)
|
Human |
E. coli |
|
Serine/threonine-protein kinase 16, also known as myristoylated and palmitoylated serine/threonine-protein kinase, Protein kinase PKL12, TGF-beta-stimulated factor 1, TSF-1, MPSK1 and STK16, is a membrane protein that is... |
| TMPH-01364
|
Galectin-9/LGALS9 Protein, Human, Recombinant (GST & His)
|
Human |
E. coli |
|
Binds galactosides. Has high affinity for the Forssman pentasaccharide. Ligand for HAVCR2/TIM3. Binding to HAVCR2 induces T-helper type 1 lymphocyte (Th1) death. Also stimulates bactericidal activity in infected macropha... |
| TMPH-03113
|
HSP90AA1 Protein, Pig, Recombinant (His)
|
Sus scrofa (Pig) |
Baculovirus |
|
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle... |
