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Search Results for " a-Neurokinin "

ターゲット

阻害剤

天然化合物

142

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
TP1008	Neurokinin A	α-Neurokinin,Substance K,Neuromedin L	Neurokinin receptor
	Neurokinin A (NKA), formerly known as Substance K, is a neurologically active peptide translated from the pre-protachykinin gene.		Neurokinin receptor
TP1385	Neurokinin A(4-10) TFA(97559-35-8 free base)	Neurokinin A(4-10) TFA	Neurokinin receptor
	Neurokinin A(4-10) TFA(97559-35-8 free base) is a tachykinin NK2 receptor agonist[1].		Neurokinin receptor
T7559	Neurokinin A(4-10)	Neurokinin A(4-10)(TFA)	Neurokinin receptor
	Neurokinin A(4-10)(TFA) is an agonist of tachykinin NK2 receptor .		Neurokinin receptor
T33654	Neurokinin A-OH	Nka OH,NkaOH,Nka-OH
	Neurokinin A-OH is the C-terminal free acid derivative of neurokinin A.
T33653	Neurokinin A (4-10), nle(10)-	10-Nle-neurokinin A (4-10)
	Neurokinin A (4-10), nle(10)- is a neurologically active peptide translated from the pre-protachykinin gene. Neurokinin A has many excitatory effects on mammalian nervous systems and on the mammalian inflammatory and pai...
TP1100	[bAla8]-Neurokinin A(4-10)	MEN 10210
	[bAla8]-Neurokinin A(4-10) is a neurokinin 2 (NK2) receptor agonist.
T80915	Tyr0-Neurokinin A
	Tyr0-Neurokinin A, a member of the tachykinin peptide family, acts as an agonist for the Tacr2 receptor. It is utilized in research focused on insulin resistance, obesity, and diabetes [1] [2].
T64680	Neurokinin A trifluoroacetate
	Neurokinin A trifluoroacetate is a useful organic compound for research related to life sciences and the catalog number is T64680.
T75729	Neurokinin A TFA
	Neurokinin A TFA (Substance K TFA), a peptide neurotransmitter belonging to the tachykinin family, functions through the NK-2 receptor. It serves as a significant mediator in human airway and gastrointestinal tissues [1]...
T75742	Neurokinin A(4-10) TFA
	Neurokinin A (4-10) TFA is a tachykinin NK 2 receptor agonist [1] .
T76428	(β-Ala8)-Neurokinin A (4-10)
	(β-Ala8)-Neurokinin A (4-10), a neuropeptide, acts as a potent and selective agonist for the NK-2 tachykinin receptor [1].
T76426	[Lys5,MeLeu9,Nle10]Neurokinin A(4-10)
	[Lys5,MeLeu9,Nle10]Neurokinin A(4-10) (LMN-NKA), a Neurokinin A analogue, serves as a selective and potent agonist for the NK2 receptor (NK2R). This compound exhibits prokinetic activity, making it a valuable tool for re...
T76635	(Trp7,β-Ala8)-Neurokinin A (4-10)
	(Trp7,β-Ala8)-Neurokinin A (4-10) is a potent neurokinin-3 (NK3) antagonist [1] .
T10056	Neurokinin antagonist 1		Neuropeptide Y Receptor
	Neurokinin antagonist 1 is a potent is a neuropeptide antagonist that can be used to study neurological disorders.		Neuropeptide Y Receptor
TP1087	Substance P	Neurokinin P	Endogenous Metabolite , Neurokinin receptor
	Substance P (Neurokinin P) (SP) is an undecapeptide (a peptide composed of a chain of 11 amino acid residues) member of the tachykinin neuropeptide family.		Endogenous Metabolite , Neurokinin receptor
T1743	Aprepitant	MK-869,MK-0869,L-754030,Aprepitant`	HIV Protease , Antibacterial , Antibiotic , Neurokinin receptor
	Aprepitant (Aprepitant`) is a Substance P/Neurokinin-1 Receptor Antagonist. The mechanism of action of aprepitant is as a Neurokinin 1 Antagonist, and Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 2C9 Inducer, and C...
T22811L	GR 94800 acetate	GR 94800 acetate (141636-65-9 free base)	Neurokinin receptor
	GR 94800 acetate is a potent and selective neurokinin 2(NK-2) antagonist.		Neurokinin receptor
T7209	Maropitant		Neurokinin receptor
	Maropitant is a selective neurokinin (NK1) receptor antagonist.		Neurokinin receptor
T68068	Ezlopitant	CJ 11974,CJ-11974,CJ11974	Neurokinin receptor
	Ezlopitant (CJ-11974) is a small molecule neurokinin-1-receptor (NK1) antagonist used to treat nausea, vomiting and pain.		Neurokinin receptor
T38144	Elinzanetant		Neurokinin receptor
	Elinzanetant is a dual antagonist of neurokinin (NK) receptors 1 and 3 and modulates reproductive hormone secretion.		Neurokinin receptor
T6905	Netupitant	Ro 67-31898/000,CID 6451149	Neurokinin receptor
	Netupitant (CID 6451149) is a specific neurokinin 1 (NK1) receptor antagonist (Ki: 0.95 nM).		Neurokinin receptor
T69140	Burapitant	SSR 240600	Neurokinin receptor
	Burapitant (SSR 240600) is a novel non-peptide tachykinin neurokinin 1 (NK) receptor antagonist with anti-coke oven and antidepressant activity.		Neurokinin receptor
TP1086	Men 10376 TFA(135306-85-3,free)	Men 10376 TFA,Neurokinin-2 receptor antagonist TFA	Neurokinin receptor
	Men 10376 TFA(135306-85-3,free) (Neurokinin-2 receptor antagonist TFA) is an effective and selective tachykinin nk-2 receptor antagonist with a K I value of 4.4 M for the nk-2 receptor in the small intestine of rats.		Neurokinin receptor
T68068L	(R)-CJ 11974		Neurokinin receptor
	(R)-CJ 11974 is a novel non-peptide neurokinin NK1 substance P receptor antagonist with potential analgesic activity that can be used to study chemotherapy-induced vomiting.		Neurokinin receptor
TP1851L	Scyliorhinin II acetate		Neurokinin receptor
	Scyliorhinin II acetate is a selective agonist of the neurokinin-3 (NK3) receptor (Ki = 2.5 nM) in rat cerebral cortex.		Neurokinin receptor
T19518L	Physalaemin acetate		Neurokinin receptor
	Physalaemin acetate is a non-mammalian tachykinin with high affinity when binding selectively to neurokinin-1 (NK1) receptor.		Neurokinin receptor
T25615	Lanepitant	LY303870,LY-303870,LY 303870	Others
	Lanepitant (LY303870) is a nonpeptide neurokinin-1 (NK-1) antagonist with analgesic activity that inhibits neurogenic dura mater inflammation and is used for the prevention of migraine.		Others
T25616	Lanepitant 2HCl	LY303870 dihydrochloride,LY 303870 dihydrochloride,LY-303870 dihydrochloride,Lanepitant dihydrochloride	Neurokinin receptor
	Lanepitant 2HCl is a non-peptide neurokinin-1 receptor antagonist with analgesic and anti-inflammatory activity.Lanepitant 2HCl inhibits the binding of Substance P to the neurokinin-1 receptor, inhibits neurogenic inflam...		Neurokinin receptor
T8235	L-732138		Neurokinin receptor
	L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM)		Neurokinin receptor
T3724	Rolapitant hydrochloride	Rolapitant HCl	Neurokinin receptor
	Rolapitant (SCH619734) hydrochloride is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a K i of 0.66 nM. Rolapitant hydrochloride (Rolapitant HCl) does not interact with CY...		Neurokinin receptor
T3716	Rolapitant	SCH619734	Neurokinin receptor
	Rolapitant (SCH619734) Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. ...		Neurokinin receptor
T9417L	Gamma-preprotachykinin amide (72-92) acetate	gamma-preprotachykinin amide (72-92) acetate (114882-65-4 Free base)	Others
	gamma-preprotachykinin amide (72-92) acetate is a 21 amino acid peptide belonging to the tachykinin (TK) family and including neurokinin A (NKA) in its C-terminal sequence. gamma-preprotachykinin amide (72-92) acetate po...		Others
T76427	(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B
	(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B functions as a competitive antagonist to the Neurokinin B receptor, exhibiting a pA2 value of 5.5. Notably, it does not affect Substance P or Neurokinin A [1].
T33264	Mdl 28564	Mdl28,564,Mdl-28,564,Mdl 28,564,Mdl28564,Mdl-28564
	Mdl 28564 is a neurokinin A analog.
T68556	GW679769
	GW679769 is a neurokinin-1 receptor antagonist.
T24285	L 363851	L363851,L-363851,L363,851,L 363,851,L-363,851
	L 363851 is a neurokinin B agonist.
T70587	CJ-12255
	CJ-12255 is a Neurokinin-1 Receptor Antagonist.
T69295	DNK 333
	DNK 333 is a dual neurokinin NK1/NK2 receptor antagonist.
T29234	ZM 253270	ZM253270,ZM-253270
	ZM 253270 is an nonpeptide neurokinin A antagonist.
T68519	Maropitant citrate anhydrous
	Maropitant citrate anhydrous is a neurokinin (NK1) receptor antagonist.
T24447	Men 10208	Men-10208,Thr-asp-tyr-trp-val-trp-trp-arg-NH2,Men10208
	Men 10208 is an antagonist of the neurokinin A receptor.
T27175	Dilopetine Citrate	E-6006 Citrate,E-6039,E6039,E 6039
	Dilopetine Citrate, a tachykinin receptor modulator and a neurokinin receptor modulator, is used potentially for the treatment of depression.
T69720	CJ-17493 (free base)
	CJ-17493 (free base) is a Neurokinin-1 Receptor Antagonist.
T69184	Figopitant
	Figopitant is a tachykinin neurokinin-1 antagonist.
T70455	Nolpitantium besilate
	Nolpitantium besilate is a neurokinin-1 receptor antagonist.
T69852	CS-003 HCl
	CS-003 HCl is a TNRA - triple neurokinin receptor antagonist.
TQ0087	NKP608		Neurokinin receptor
	NKP608 is a selective and potent antagonist at the neurokinin-1 (NK-1) receptor both in vitro(IC50: 2.6 nM) and in vivo.		Neurokinin receptor
TP1279	Neurokinin B (TFA)	Neurokinin B TFA
	Neurokinin B TFA belongs to the tachykinin family.Neurokinin B binds to a series of GPCR, including neurokinin receptors 1 (NK1R), NK2R, and nk3r, to modulate their biological effects
TP2155	Substance P TFA	Neurokinin P TFA	Others
	Substance P TFA (Neurokinin P TFA) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS, targeting the neurokinin 1 receptor (NK1-receptor, NK1R).		Others
T28676	SB 235375	SB-235375,SB235375
	SB 235375 is a potent and selective antagonist of neurokinin-3 receptor with a low central nervous system-penetrant.

Compounds

Neurokinin A

TP1008

Synonym: α-Neurokinin,Substance K,Neuromedin L

Target: Neurokinin receptor

Neurokinin A(4-10) TFA(97559-35-8 free base)

TP1385

Synonym: Neurokinin A(4-10) TFA

Target: Neurokinin receptor

Neurokinin A(4-10)

T7559

Synonym: Neurokinin A(4-10)(TFA)

Target: Neurokinin receptor

Neurokinin A-OH

T33654

Synonym: Nka OH,NkaOH,Nka-OH

Target:

Neurokinin A (4-10), nle(10)-

T33653

Synonym: 10-Nle-neurokinin A (4-10)

Target:

[bAla8]-Neurokinin A(4-10)

Neurokinin A trifluoroacetate

Neurokinin A(4-10) TFA

T75742

Synonym:

Target:

(β-Ala8)-Neurokinin A (4-10)

T76428

Synonym:

Target:

[Lys5,MeLeu9,Nle10]Neurokinin A(4-10)

T76426

Synonym:

Target:

(Trp7,β-Ala8)-Neurokinin A (4-10)

T76635

Synonym:

Target:

Neurokinin antagonist 1

T10056

Synonym:

Target: Neuropeptide Y Receptor

Substance P

TP1087

Synonym: Neurokinin P

Target: Endogenous Metabolite, Neurokinin receptor

Aprepitant

T1743

Synonym: MK-869,MK-0869,L-754030,Aprepitant`

Target: HIV Protease, Antibacterial, Antibiotic, Neurokinin receptor

GR 94800 acetate

T22811L

Synonym: GR 94800 acetate (141636-65-9 free base)

Target: Neurokinin receptor

Maropitant

T7209

Synonym:

Target: Neurokinin receptor

Ezlopitant

T68068

Synonym: CJ 11974,CJ-11974,CJ11974

Target: Neurokinin receptor

Elinzanetant

T38144

Synonym:

Target: Neurokinin receptor

Netupitant

T6905

Synonym: Ro 67-31898/000,CID 6451149

Target: Neurokinin receptor

Burapitant

T69140

Synonym: SSR 240600

Target: Neurokinin receptor

Men 10376 TFA(135306-85-3,free)

TP1086

Synonym: Men 10376 TFA,Neurokinin-2 receptor antagonist TFA

Target: Neurokinin receptor

(R)-CJ 11974

T68068L

Synonym:

Target: Neurokinin receptor

Scyliorhinin II acetate

TP1851L

Synonym:

Target: Neurokinin receptor

Physalaemin acetate

T19518L

Synonym:

Target: Neurokinin receptor

Lanepitant

T25615

Synonym: LY303870,LY-303870,LY 303870

Target: Others

Lanepitant 2HCl

T25616

Synonym: LY303870 dihydrochloride,LY 303870 dihydrochloride,LY-303870 dihydrochloride,Lanepitant dihydrochloride

Target: Neurokinin receptor

L-732138

T8235

Synonym:

Target: Neurokinin receptor

Rolapitant hydrochloride

T3724

Synonym: Rolapitant HCl

Target: Neurokinin receptor

Rolapitant

T3716

Synonym: SCH619734

Target: Neurokinin receptor

gamma-preprotachykinin amide (72-92) acetate

T9417L

Synonym: gamma-preprotachykinin amide (72-92) acetate (114882-65-4 Free base)

Target: Others

(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B

Synonym: Mdl28,564,Mdl-28,564,Mdl 28,564,Mdl28564,Mdl-28564

Synonym: L363851,L-363851,L363,851,L 363,851,L-363,851

Synonym: ZM253270,ZM-253270

Target:

Maropitant citrate anhydrous

Synonym: Men-10208,Thr-asp-tyr-trp-val-trp-trp-arg-NH2,Men10208

Target:

Dilopetine Citrate

T27175

Synonym: E-6006 Citrate,E-6039,E6039,E 6039

Nolpitantium besilate

Target: Neurokinin receptor

Neurokinin B (TFA)

TP1279

Synonym: Neurokinin B TFA

Target:

Substance P TFA

TP2155

Synonym: Neurokinin P TFA

Target: Others

SB 235375

T28676

Synonym: SB-235375,SB235375

Target:

カタログ番号	製品名	別名	ターゲット
T38033	Benzomalvin B
	Benzomalvin B is a fungal metabolite originally isolated from Penicillium. It acts as an antagonist of neurokinin-1 (NK1) receptors, inhibiting binding of substance P by 24% in vitro when used at a concentration of 100 μ...
T71833	Acetylaszonalenin
	Acetylaszonalenin is a fungal metabolite that has been found in A. flavipes.1 It acts as an antagonist of neurokinin-1 (NK1) receptors, inhibiting binding of substance P with a Ki value of 170 μM.

天然物製品

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-00892	TAC1 Protein, Human, Recombinant (His)	Human	E. coli
	Protachykinin-1(TAC1) is a secreted protein and belongs to the tachykinin family. TAC1 is encoded by the TAC1 gene. This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, ...
TMPJ-01379	TAC3 Protein, Human, Recombinant (His)	Human	E. coli
	Tachykinin 3 (TAC3) is a secreted protein that belongs to the Tachykinin family. Tachykinins are active peptides that excite neurons and evoke behavioral responses; they are potent vasodilators and secretagogues, and con...
TMPK-01415	APC-equivalent Peptide Ready HLA-A*02:01&B2M Tetramer Protein, Human, MHC (His)	Human	HEK293 Cells
	Peptide Ready HLA-A02:01&B2M Tetramer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A02:01. Peptide ready MHC molecules comprising human HLA alleles and B2M...
TMPK-01421	Peptide Ready HLA-A*02:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	HLA-A02:01&B2M&Peptide ready Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A02:01. Peptide ready MHC molecules comprising human HLA alleles and B2M,...
TMPK-01422	Peptide Ready HLA-A*02:01&B2M Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Peptide Ready HLA-A02:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A02:01. Peptide ready MHC molecules comprising human HLA alleles and B2M,...
TMPK-01410	Peptide Ready HLA-A*24:02&B2M Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Peptide Ready HLA-G&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-G. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can b...
TMPK-01420	Peptide Ready HLA-A*03:01&B2M Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Peptide Ready HLA-A03:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A03:01. Peptide ready MHC molecules comprising human HLA alleles and B2M,...
TMPK-01404	HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated	Human	E. coli
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01449	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (E. coli, His & Avi)	Human	E. coli
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses,...
TMPK-01428	HLA-A*11:01&B2M&KRAS G12D (VVGADGVGK) Monomer Protein, Human, MHC (His & Avi)	Human	E. coli
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01552	HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell prolifer...
TMPK-01447	HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
TMPK-01461	HLA-A*11:01&B2M&KRAS G12S (VVVGASGVGK) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01453	HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01439	HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01532	HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell prolifer...
TMPK-01482	HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01496	HLA-A*01:01&B2M&CT83 (NTDNNLAVY) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Cancer/testis antigens 83 (CT83), also called KK-LC-1 or CXorf61, recognized by cytotoxic T lymphocytes (CTL), has become a promising target for immunotherapy.
TMPK-01500	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses,...
TMPK-01508	HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell prolifer...
TMPK-01537	HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01480	HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upreg...
TMPK-01517	HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upreg...
TMPK-01550	HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Melanoma-associated antigen 4 is a protein that in humans is encoded by the MAGEA4 gene.The MAGE- A4 antigen is among the most commonly expressed cancer testis antigens. The Human HLA-A*0201 MAGE-A4 (GVYDGREHTV) complex ...
TMPK-01530	HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel...
TMPK-01519	HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01433	HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01498	HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel...
TMPK-01515	HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01445	HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	MAGE-A1 belongs to the chromosome X-clustered genes of cancer-testis antigen family and is normally expressed in the human germ line but is also overexpressed in various tumors.
TMPK-01468	HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Melanoma antigen recognized by T cell-1 (Mart-1), one of the melanosome-specific proteins, also recognized by cytotoxicity T lymphocytes as a marker. Mart-1 is considered to play a critical role in the immunotherapy for ...
TMPK-01459	HLA-A*02:01&B2M&MAGE-A4 or MAGE-A8 (KVLEHVVRV) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	MAGE-A4 and MAGE-A8 are type I membes of the melanoma associated antigen (MAGE) family. The MAGE family is a large, highly conserved group of proteins that share a common MAGE homology domain. Both MAGE-A4 and MAGE-A8 an...
TMPK-01495	HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine im...
TMPK-01554	HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en...
TMPK-01546	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses,...
TMPK-01454	HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
TMPK-01455	HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
TMPK-01526	HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01497	HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled	Human	HEK293 Cells
	NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses,...
TMPK-01483	HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01457	HLA-A*11:01&B2M&KRAS G12A (VVVGAAGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01432	HLA-A*11:01&B2M&KRAS G12A (VVVGAAGVGK) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01406	HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled	Human	HEK293 Cells
	PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
TMPK-01419	Peptide Ready HLA-A*03:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	Peptide Ready HLA-A03:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A03:01. Peptide ready MHC molecules comprising human HLA alleles and B2M,...
TMPK-01425	Peptide Ready HLA-A*11:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	Peptide Ready HLA-A11:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A11:01. Peptide ready MHC molecules comprising human HLA alleles and B2M,...
TMPK-01426	Peptide Ready HLA-A*11:01&B2M Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Peptide Ready HLA-A11:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A11:01. Peptide ready MHC molecules comprising human HLA alleles and B2M,...
TMPK-01409	Peptide Ready HLA-A*24:02&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	Peptide Ready HLA-G&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-G. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can b...
TMPK-01405	HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi)	Human	E. coli
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01400	HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated	Human	E. coli
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01429	HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated	Human	E. coli
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
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