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カタログ番号 | 製品名 | 別名 | ターゲット |
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T17208 | USL311 | CXCR | |
USL311 is a CXCR4 receptor antagonist which prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4. USL311 inhibits CXCR4 activation and decreases proliferation and migration of CXCR4-expressing... | |||
T17158 | Trans-AUCB | t-AUCB | Epoxide Hydrolase |
trans-AUCB (t-AUCB) is an effective and selective soluble epoxide hydrolase inhibitor (IC50s: 1.3 nM, 8 nM, 8 nM for hsEH, mouse sEH and rat sEH, respectively). | |||
T2028 | NG 52 | NG52,NG-52,Compound 52 | CDK |
NG 52 (NG-52) is a cell-permeable, reversible, and ATP-compatible inhibitor of the cell cycle-regulating kinase Cdc28p and the related Pho85p kinase. | |||
T23480 | U-83836E | Others | |
U-83836E (lazaroid ) has neuroprotective activity and anti-tumor activity, inhibits glioma cell proliferation, inhibits tumor necrosis factor and reverses endotoxin-induced shock. | |||
T21842 | 2-fluoro Palmitic Acid | ||
2-Fluoropalmitic acid, functioning as an acyl-CoA synthetase inhibitor, is a potential anti-glioma agent. It diminishes the viability and stem-like characteristics of glioma stem cells (GSCs) and hinders the proliferatio... | |||
T74365 | Chol-CTPP | ||
Chol-CTPP, a ligand with a dual targeting effect on the blood-brain barrier (BBB) and glioma cells, serves as the precursor to Lip-CTPP when combined with another mitochondria-targeting ligand (Chol-TPP). Lip-CTPP emerge... | |||
T60661 | CP681301 | ||
CP681301 is a potent inhibitor of CDK5 with antiproliferative activity. CP681301 exhibits anti-tumor activity in Drosophila. CP681301 decreases the expression of CD133, OLIG2, SOX2, KI67, pCDK5 protein level in Glioma st... | |||
T68324 | KCN1 | ||
KCN1, a novel synthetic sulfonamide, is a HIF pathway inhibitor with potential anticancer activity in vitro and in vivo anti-pancreatic cancer activities and preclinical pharmacology. KCN1 specifically inhibited HIF repo... | |||
T35573 | Adenosine 5’-methylenediphosphate (hydrate) | ||
Adenosine 5’-methylenediphosphate is an inhibitor of ecto-5’-nucleotidase, also known as CD73, with a Kivalue of 37 nM.1It inhibits cAMP accumulation induced by adenosine 5’-monophosphate , adenosine 5’-diphosphate , or ... |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T4S0094 | Hydroxygenkwanin | Luteolin 7-methylether,7-O-Methylluteolin | Antioxidant |
1. Hydroxygenkwanin (Luteolin 7-methylether) possesses significant the antioxidative activity . 2. Hydroxygenkwanin has cytotoxicity, may be an effective natural product to treat glioma, and the combination of Apigenin a... | |||
TN1933 | Mitraphylline | IL Receptor , TNF , NF-κB | |
Mitraphylline has antiproliferative effects on human glioma and neuroblastoma cell lines. It also has anti-inflammatory activity, it inhibits lipopolysaccharide-mediated activation of primary human neutrophils. | |||
T2945 | Germacrone | P450 , Antiviral , Influenza Virus | |
Germacrone, a major active component found in Curcuma zedoaria oil product, shows anti-inflammatory, antiandrogenic, and antivirus activities. It also inhibits the proliferation of glioma cells by promoting apoptosis. | |||
T72904 | Norswertianin | ||
Norswertianin, a xanthone-based compound, acts as a potent anti-glioma agent. It promotes differentiation of GBM cells via oxidative stress and autophagy dependent on Akt/mTOR signaling. | |||
T10910 | Cycloartenol | Others | |
Cyclopentanol is a plant sterol compound and one of the key precursors for biosynthesis of various sterol compounds. Cycloartenol inhibits the migration of glioma cells and inhibits the phosphorylation of p38 MAP kinase.... | |||
T8199 | (±)-α-Bisabolol | Bisabolol | Apoptosis , Antioxidant |
(±)-α-Bisabolol (Bisabolol) isa sesquiterpenol extracted from essential oils of chamomile, candida and other plants. It isa natural antiseptic with soothing, antiirritating, anti-inflammatory, antioxidant and anticancer ... |