ホーム 計算ツール
代理店ログイン

検索結果

Search Results for " backbone "

ターゲット

19

阻害剤

9

天然化合物

7

リコンビナントタンパク質

1

ライブラリー

カタログ番号 製品名 別名 ターゲット
T13507 4,4'-Iminodiphenol Leucoindophenol Estrogen/progestogen Receptor
4,4'-Iminodiphenol (Leucoindophenol) is an inactive estrogen receptor ligand with a diphenylamine backbone.
T77504 JAK1/2/3 Inhibitor 1 PKA
JAK1/2/3 Inhibitor 1 is a potent protein kinase inhibitor.JAK1/2/3 Inhibitor 1 has antitumor activity that inhibits the growth of a variety of cancer cell lines. It inhibits the growth of cancer cells by binding to the c...
T16591 Propargyl-PEG1-SS-PEG1-PFP ester Others
Propargyl-PEG1-SS-PEG1-PFP ester is a cleavable linker consisting of a 1-unit polyethylene glycol (PEG) backbone, designed for use in the synthesis of antibody-drug conjugates (ADCs)[1].
T18488 NH2-MPAA-NODA Others
NH2-MPAA-NODA, a nitroveratryl-based photocleavable linker featuring a NODA motif and a methyl phenyl acetic acid (MPAA) backbone, serves as a radiolabel when labeled with 18F-fluoride.
T38896 VPM peptide
VPM peptide functions as a protease-cleavable dithiol cross-linker. It is capable of integration into the PEG-diacrylate (PEG-DA) macromer backbone, resulting in the formation of PEG hydrogel.
T76708 Penpulimab
Penpulimab, an anti-PD-1 monoclonal antibody featuring an IgG1 backbone, possesses antitumor activities [1].
T15993 Mal-PEG4-PFP ester Others
Mal-PEG4-PFP ester is a non-cleavable antibody-drug conjugate (ADC) linker that incorporates a Maleimide moiety, a 4-unit Polyethylene Glycol (PEG) backbone, and a Pentafluorophenyl (PFP) ester.
T34180 Psilostachyin C NSC 106392
Psilostachyin c is a member of the class of compounds known as ambrosanolides and secoambrosanolides. Ambrosanolides and secoambrosanolides are sesquiterpene lactones from the Ambrosia family, with a backbone derivative ...
T34686 Sonoflora 1 SF 1,SF-1,Sonoflora1,Sonoflora-1,SF1
Sonoflora 1, also known as SF1, a PDT photosensitivizer. Chemically, SF1 is an analog of chlorophyll in that its macrocycle backbone is porphyrin-based and the center of the porphyrin ring consists of a metal ion. Precli...
T38180 C16 Phytoceramide (t18:0/16:0)
C16 Phytoceramide (t18:0/16:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. C16 Phytoceramide (t18:0/1...
T14448 Azido-PEG4-CH2-Boc Others
Azido-PEG4-CH2-Boc is a four-unit cleavable polyethylene glycol (PEG) linker compound employed in the synthesis of antibody-drug conjugates (ADCs)[1] and PROTACs[2]. This linker is characterized by its azide functional g...
T37123 1,2-Dioctanoyl PC
Phosphatidylcholine (PC) species are a common class of phospholipids that comprise the mammalian cell membrane. 1,2-Dioctanoyl PC is a synthetic analog of natural phosphatidylcholine species containing saturated C8:O fat...
T76098 Glycerol-3-phosphate oxidase
Glycerol-3-phosphate oxidase, a crucial intermediate in glycerol metabolism, can be extracted from Escherichia coli. It serves as the backbone for phospholipids in membrane lipids and acts as a substrate in the respirato...
T73753 Neuraminic acid
Neuraminic acid, an acidic amino sugar characterized by a nine-carbon atom backbone, can be understood as the aldol-condensation product of pyruvic acid and D-mannosamine (2-amino-2-deoxy-mannose). It serves as a functio...
T37458 C18 Phytoceramide (t18:0/18:0)
C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid found in S. cerevisiae, wheat grains, and the stratum corneum layer of mammalian epidermis. Cer(t18:0/18:0) is composed of a phytosphingosine b...
T37244 Palmitoyl thio-PC
Thioester analogs of glycerophospholipids, in combination with Ellman's reagent, are convenient colorimetric substrates for the measurement of phospholipase (PL) activity. Palmitoyl thio-PC is a chromogenic PLA2 substrat...
T38291 C24 Phytosphingosine (t18:0/24:0)
C24 Phytosphingosine (t18:0/24:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. C24 Phytosphingosine (t...
T38284 C24 dihydro 1-Deoxyceramide (m18:0/24:0) C24 dihydro 1-Deoxyceramide (m18:0/24:0)
C24 dihydro 1-Deoxyceramide (m18:0/24:0) is a very long-chain atypical ceramide containing a 1-deoxysphinganine backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alan...
T38280 C22 dihydro 1-Deoxyceramide (m18:0/22:0) C22 dihydro 1-Deoxyceramide (m18:0/22:0)
C22 dihydro 1-Deoxyceramide (m18:0/22:0) is a very long-chain atypical ceramide containing a 1-deoxysphinganine backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alan...
カタログ番号 製品名 別名 ターゲット
T17155 Trabectedin Ecteinascidin 743,ET-743 Apoptosis , Reactive Oxygen Species
Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research. Trabectedin inhibits cell growth of MX-1, MCF7 and MCF7/DXR cells with IC50 values of 0...
T8240 Cis-5-Dodecenoic Acid Others
Cis-5-Dodecenoic Acid is a monounsaturated fatty acid that has a C12 chain as a backbone and a cis double bond at the C5 position.
T5658 Adamantane Others
The adamantane moiety is the structural backbone of numerous compounds and the physicochemical and biological properties of organic polyhedral compounds with practical application in the pharmaceutical industry.
T6873 Lauric Acid Dodecylic acid,dodecanoic acid,Vulvic acid,N-Dodecanoic acid Others , Endogenous Metabolite , Antibacterial
Lauric Acid (Dodecylic acid),which is found naturally in various plant and animal fats and oils, is a saturated medium-chain fatty acid with a 12-carbon backbone. It is a major component of coconut oil and palm kernel oi...
T2910 Flavonol 3-Hydroxyflavone,3-HF,Flavon-3-ol,3-Hydroxy-2-phenylchromone Others , Endogenous Metabolite
Flavonol (3-Hydroxyflavone) is a member of the class of compounds known as flavonols. 3-hydroxyflavone can be found in a number of food items such as brassicas, pomegranate, red raspberry, and fenugreek. 3-hydroxyflavone...
T4776 Glycerol Glycerin Endogenous Metabolite
Glycerol or glycerin is a colourless, odourless, viscous liquid that is sweet-tasting and mostly non-toxic. It is widely used in the food industry as a sweetener and humectant and in pharmaceutical formulations. Glycerol...
T13729 Hydrolyzed Fumonisin B1 Aminopentol Others
Hydrolyzed Fumonisin B1 is the backbone and the main hydrolysis product of the mycotoxin fumonisin B1 (FB1), can weakly inhibit ceramide synthase.
T40589 6-O-β-D-Galactopyranosyl-D-galactose
6-O-beta-D-Galactopyranosyl-D-galactose, a disaccharide, is a constituent of the polysaccharide backbone characterized by beta-(1→6) glycoside linkages, with a side chain attached to the primary chain through a beta-(1→3...
TN4592 Murrangatin IL Receptor , TNF , COX , Prostaglandin Receptor
Murrangatin may be a valuable anti-tumor-promoting agent, it can significantly inhibit Epstein-Barr virus early antigen (EBV-EA) activation, and preserve the high viability of Raji cells, it also exhibits cytotoxicity ag...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPH-00767 Gellan lyase Protein, Geobacillus stearothermophilus, Recombinant (His) Geobacillus stearothermophilus E. coli
Cleaves the glycosidic bonds of gellan backbone and releases tetrasaccharide units of glucuronyl-glucosyl-rhamnosyl-glucose with unsaturated glucuronic acid at the non-reducing terminal. The enzyme is highly specific to ...
TMPH-03385 Thyroglobulin Protein, Rat, Recombinant (His & SUMO) Rat E. coli
Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by ...
TMPH-02162 Synaptotagmin-1 Protein, Human, Recombinant (His) Human E. coli
Calcium sensor that participates in triggering neurotransmitter release at the synapse. May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. I...
TMPY-02798 NEIL1 Protein, Human, Recombinant (His) Human E. coli
NEIL1 is a member of DNA glycosylases. DNA glycosylases are a family homologous to the bacterial Fpg/Nei family. They play a role in base excision repair which is the mechanism by which damaged bases in DNA are removed a...
TMPH-01008 PNKP Protein, Human, Recombinant (His & SUMO) Human E. coli
Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini ...
TMPY-02522 OTUB2 Protein, Human, Recombinant (His) Human E. coli
Otubain 2 (OTUB2) is a member of DUBs that belong to the ovarian tumour (OTU) superfamily of proteins which consists of a five-stranded β-sheet sandwiched in between a small helical amino-terminal region consisting of α1...
TMPH-01241 TOP1 Protein, Human, Recombinant (His & Myc) Human Baculovirus Insect Cells
Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via tran...
カタログ番号 製品名
L6120 Flavonoid Natural Product Library

514 compounds
A unique collection of 514 flavonoids can be used for high throughput and high content screening;