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Search Results for " cathepsin-D "

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T37504L	Cathepsin D and E FRET Substrate acetate
	Cathepsin D and E FRET Substrate acetate is a fluorogenic substrate for cathepsins D and E but not for B, H, or L. Cathepsin D and E FRET Substrate acetate can be used in mechanistic studies on cathepsins D and E studies...
T37504	Cathepsin D and E FRET Substrate
	Mca-GKPILFFRL-Dpa-r-amide, FRET substrate for cathepsin D and E. Also cleaved by napsin A.
T38254	Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base)
	Cathepsin D and E FRET Substrate acetate is a fluorogenic substrate selectively cleaved by cathepsins D and E at the Phe-Phe amide bond, without activity towards cathepsins B, H, or L. This specificity makes it an essent...
T16777	ROC-325		Apoptosis , Autophagy
	ROC-325 is an effective and orally active inhibitor of autophagy with anticancer activity. ROC-325 induces renal cell carcinoma apoptosis and exhibits favorable selectivity.		Apoptosis , Autophagy
T12188	NB-360		BACE
			BACE
T3695	Pepstatin	Pepstatin A,Pepsin Inhibitor S 735A,Ahpatinin C	Amino Acids and Derivatives , Proteasome , HIV Protease , Autophagy
	Pepstatin (Pepsin Inhibitor S 735A) is a specific aspartic proteases inhibitor produced by actinomycetes, and inhibits the aspartic proteases cathepsin D, pepsin and renin.
T2639	LY2811376		Beta Amyloid , Beta-Secretase , BACE
	LY2811376, an orally available non-peptidic β-secretase(BACE1) inhibitor (IC50: 239-249 nM), can decrease Aβ secretion (EC50: 300 nM). It has 10-fold selectivity towards BACE1 over BACE2, and more than 50-fold inhibition...		Beta Amyloid , Beta-Secretase , BACE
T27595	Imarikiren HCl	TAK-272 hydrochloride,TAK-272 HCl. Imarikiren HCl \|,TAK272,TAK 272,TAK-272
	Imarikiren is a potent, selective and orally active direct renin inhibitor. TAK-272 shows potent inhibitory activity against human renin (IC50 = 2.1 nM) in hPRA assay and excellent selectivity against other aspartic prot...
T76614	H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH
	H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH is a water-soluble polypeptide capable of acting as a substrate for enzymes cathepsin D, pepsin, and pepsinogen, holding potential applications in biochemical analysis [1] [2].
T37661	LY 2886721 Hydrochloride
	Potent and selective β-secretase (BACE) inhibitor (IC50 values are 10.2 and 20.3 nM for human BACE2 and BACE1, respectively). Displays >5,000-fold selectivity for BACE over other proteases including cathepsin D, pepsin a...
T83679	Parasin I (catfish) TFA
	Parasin I, a peptide fragment derived from the N-terminal region of histone H2A in catfish (P. asotus), plays a critical role in host defense. This antimicrobial peptide is produced through the action of cathepsin D on h...
T13434	β-Secretase Inhibitor IV		Others
	β-Secretase Inhibitor IV is a potent, cell-active inhibitor of BACE-1(IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively).		Others

Compounds

Cathepsin D and E FRET Substrate acetate

T37504L

Synonym:

Target:

Cathepsin D and E FRET Substrate

T37504

Synonym:

Target:

Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base)

Target: Apoptosis, Autophagy

Synonym: Pepstatin A,Pepsin Inhibitor S 735A,Ahpatinin C

Target: Amino Acids and Derivatives, Proteasome, HIV Protease, Autophagy

LY2811376

T2639

Synonym:

Target: Beta Amyloid, Beta-Secretase, BACE

Imarikiren HCl

T27595

Synonym: TAK-272 hydrochloride,TAK-272 HCl. Imarikiren HCl |,TAK272,TAK 272,TAK-272

Target:

H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH

T76614

Synonym:

Target:

LY 2886721 Hydrochloride

T37661

Synonym:

Target:

Parasin I (catfish) TFA

T83679

Synonym:

Target:

β-Secretase Inhibitor IV

T13434

Synonym:

Target: Others

カタログ番号	製品名	別名	ターゲット
T8709	Nandrolone phenylpropionate	Nandrolone phenpropionate	Androgen Receptor
	Nandrolone phenylpropionate (Nandrolone phenpropionate) is an androgen receptor agonist. It mainly used to treat women with breast cancer and osteoporosis		Androgen Receptor

天然物製品

Nandrolone phenylpropionate

T8709

Synonym: Nandrolone phenpropionate

Target: Androgen Receptor

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-02450	Cathepsin D Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cathepsin D Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44 kDa and the accession number is P07339.
TMPY-00733	Cathepsin D Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Cathepsin D Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.4 kDa and the accession number is P18242.
TMPH-03261	Cathepsin D Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation. Cathepsin D Protein, Rat, Recombinant (His & Myc) is exp...
TMPH-00437	Cathepsin D Protein, Cricetulus griseus, Recombinant (His & SUMO)	Chinese hamster	E. coli
	N/A. Cathepsin D Protein, Cricetulus griseus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 53.3 kDa and the accession number is G3I4W7.
TMPJ-00845	CTSE Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cathepsin E (CTSE) is a gastric aspartyl protease that functions as a disulfide-linked homodimer. It is a member of the Peptidase C1 family, and has a specificity similar to that of Pepsin A and Cathepsin D. CTSE is loca...
TMPY-00729	Cystatin D Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cystatins are natural inhibitors of papain-like (family C1) and legumain-related (family C13) cysteine peptidases. The mammalian cystatin superfamily members are of three major types, including the type 1 cystatins (stef...