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Search Results for " docking "

9

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4

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21

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1

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カタログ番号 製品名 別名 ターゲット
T24676 PS423 PS210AM,PS 210 AM,PS 423,PS210-AM,PS-423
PS423 is a substrate-selective protein kinase PDK1 inhibitor that acts by binding to the PIF-pocket allosteric docking site.
T16450 PDK1-IN-RS2 PDK
PDK1-IN-RS2 inhibits the activation of the downstream kinases S6K1 by PDK1. PDK1-IN-RS2 is a mimic of the peptide docking motif (PIFtide) and is a substrate-selective PDK1 inhibitor (Kd: 9 μM).
T81743 MTORC1-IN-1 mTOR
mTORC1-IN-1 (T1), a rapamycin homologue (rapalog) and selective inhibitor of mTORC1, controls cell growth and metabolism, with implications in various diseases such as cancer. It interacts with mTORC1 by attaching to the...
T36969 ARN24139
ARN24139 is a topoisomerase II poison (IC50= 7.3 μM in a topoisomerase II decatenation assay).1It inhibits proliferation of DU145, HeLa, and A549 cells (IC50s = 4.7, 3.8, and 3.1 μM, respectively). 1.Arencibia, J.M., Bri...
T36187 Celecoxib Carboxylic Acid
Celecoxib carboxylic acid is an inactive metabolite of the COX-2 inhibitor celecoxib .1,2It is formed from celecoxib primarily by the cytochrome P450 (CYP) isoform CYP2C9. 1.Liu, H., Huang, X., Shen, J., et al.Inhibitory...
T36409 Roccellic Acid
Roccellic acid is a lichen secondary metabolite that has been found in R. montagnei and has antibacterial and anticancer activities.1,2 It is active against the bacteria S. gordonii and P. gingivalis (MIC = 46.9 μg/ml fo...
T35438 (5E)-7-Oxozeaenol
(5E)-7-Oxozeaenol is a resorcylic acid lactone that has been found in the fungus MSX 63935 and has enzyme inhibitory and anticancer activities.1,2 It inhibits TGF-β-activated kinase 1 (TAK-1; IC50 = 1.3 μM).1 (5E)-7-Oxoz...
T35524 (1S)-Calcitriol
(1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3), a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3), exerts potent actions through vitamin D receptor (VDR) activation, including the inhibition of keratin...
T36424 DSPE-PEG(2000)-amine (sodium salt)
DSPE-PEG(2000)-amine is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE . It has been used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents.1,2,3D...
カタログ番号 製品名 別名 ターゲット
T13206 Tris(2,4-di-tert-butylphenyl)phosphate Phospholipase
Tris(2,4-di-tert-butylphenyl)phosphate is a natural compound isolated from Vitex negundo L. with anti-inflammatory activity.
T17143 Toyocamycin Vengicide Apoptosis , Others , IRE1 , Antibiotic , Antifungal
Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis.
T5S1882 Songorine Napellonine,Zongorine,Bullatine G Others , GABA Receptor
Songorine (Napellonine) shows favorable anti-tumor activity in preliminary pharmacological verification trials including cell proliferation and molecular docking assays.
T4969 Guanosine 5'-triphosphate trisodium salt GTP Trisodium salt,5'-GTP trisodium salt Endogenous Metabolite
Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of se...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-02245 SNAP-25 Protein, Human, Recombinant (His) Human E. coli
Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains...
TMPJ-00611 SFP Protein, B.subtilis, Recombinant (His) Bacillus subtilis E. coli
The Bacillus subtilis enzyme Sfp, required for production of the lipoheptapeptide antibiotic surfactin, posttranslationally phosphopantetheinylates a serine residue in each of the seven peptidyl carrier protein domains o...
TMPH-02166 STXBP1 Protein, Human, Recombinant Human E. coli
Participates in the regulation of synaptic vesicle docking and fusion through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machiner...
TMPH-02165 STXBP1 Protein, Human, Recombinant (His) Human HEK293 Cells
Participates in the regulation of synaptic vesicle docking and fusion through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machiner...
TMPH-02111 SRP72 Protein, Human, Recombinant (GST) Human E. coli
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. Binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might intera...
TMPK-00809 CD37 Protein, Human, Recombinant (His) Human HEK293 Cells
CD37 is a tetraspanin expressed prominently on the surface of B cells. It is an attractive molecular target exploited in the immunotherapy of B cell-derived lymphomas and leukemia. Currently, several monoclonal antibodie...
TMPY-00151 Alpha SNAP Protein, Human, Recombinant (His) Human E. coli
NAPA (NSF Attachment Protein Alpha) is a Protein Coding gene. This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to ta...
TMPY-03629 Syntaxin 8 Protein, Human, Recombinant (His) Human HEK293 Cells
STX8, also known as syntaxin 8, directly interacts with HECTd3. STX8 forms the SNARE complex with syntaxin 7, vti1b and endobrevin. STX8 belongs to the syntaxin family. Members of this family are key molecules implicated...
TMPJ-00584 Bc1-w Protein, Human, Recombinant (His) Human E. coli
Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in thebrain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing thre...
TMPY-03604 VAMP3 Protein, Human, Recombinant (His) Human E. coli
VAMP3, also known as cellubrevin, is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components...
TMPJ-00305 SIRP alpha Protein, Cynomolgus, Recombinant (aa 31-369, His) Cynomolgus HEK293 Cells
Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can expre...
TMPJ-00306 SIRP alpha Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can expre...
TMPJ-01182 SIRP alpha Protein, Mouse, Recombinant (MIgG2a) Mouse HEK293 Cells
SIRPα is a type I transmembrane glycoprotein.It contains two Ig-like C1-type domains and one Ig-like V-type domain. Mouse SIRP alpha ECD shares 61%, 75%, 62%, 61%, and 59% aa sequence identity with human, rat, equine, bo...
TMPH-01524 KPNA1 Protein, Human, Recombinant (His) Human E. coli
Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate com...
TMPH-01256 Dystonin Protein, Human, Recombinant (His & SUMO) Human E. coli
Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and musc...
TMPY-01820 Munc18-1/STXBP1 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
Syntaxin-binding protein 1, also known as N-Sec1, Protein unc-18 homolog 1, MUNC18-1 and STXBP1, is a peripheral membrane protein that belongs to the STXBP / unc-18 / SEC1 family. STXBP1 is an evolutionally conserved neu...
TMPH-01257 Dystonin Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and musc...
TMPY-01960 Munc18c/STXBP3 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
Syntaxin-binding protein 3, also known as Platelet Sec1 protein, Protein unc-18 homolog 3, Protein unc-18 homolog C, Unc-18C, Unc18-3 and STXBP3, is a cytoplasm protein which belongs to the STXBP/unc-18/SEC1 family. STXB...
TMPY-04402 CSNK1G1 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
Casein kinase I isoform gamma-1, also known as CSNK1G1, is a member of the protein kinase superfamily, CK1 Ser/Thr protein kinase family and casein kinase I subfamily. Thecasein kinase I family of protein kinases are ...
TMPY-03435 NCKIPSD Protein, Human, Recombinant (GST) Human E. coli
NCKIPSD is localized exclusively in the cell nucleus. It plays a role in signal transduction and may function in the maintenance of sarcomeres and the assembly of myofibrils into sarcomeres. NCKIPSD also plays an importa...
TMPH-02274 JAK2 Protein, Human, Recombinant (His) Human E. coli
Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cyto...
SNAP-25 Protein, Human, Recombinant (His)
TMPY-02245
Species: Human
Expression System: E. coli
SFP Protein, B.subtilis, Recombinant (His)
TMPJ-00611
Species: Bacillus subtilis
Expression System: E. coli
STXBP1 Protein, Human, Recombinant
TMPH-02166
Species: Human
Expression System: E. coli
STXBP1 Protein, Human, Recombinant (His)
TMPH-02165
Species: Human
Expression System: HEK293 Cells
SRP72 Protein, Human, Recombinant (GST)
TMPH-02111
Species: Human
Expression System: E. coli
CD37 Protein, Human, Recombinant (His)
TMPK-00809
Species: Human
Expression System: HEK293 Cells
Alpha SNAP Protein, Human, Recombinant (His)
TMPY-00151
Species: Human
Expression System: E. coli
Syntaxin 8 Protein, Human, Recombinant (His)
TMPY-03629
Species: Human
Expression System: HEK293 Cells
Bc1-w Protein, Human, Recombinant (His)
TMPJ-00584
Species: Human
Expression System: E. coli
VAMP3 Protein, Human, Recombinant (His)
TMPY-03604
Species: Human
Expression System: E. coli
SIRP alpha Protein, Cynomolgus, Recombinant (aa 31-369, His)
TMPJ-00305
Species: Cynomolgus
Expression System: HEK293 Cells
SIRP alpha Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00306
Species: Human
Expression System: HEK293 Cells
SIRP alpha Protein, Mouse, Recombinant (MIgG2a)
TMPJ-01182
Species: Mouse
Expression System: HEK293 Cells
KPNA1 Protein, Human, Recombinant (His)
TMPH-01524
Species: Human
Expression System: E. coli
Dystonin Protein, Human, Recombinant (His & SUMO)
TMPH-01256
Species: Human
Expression System: E. coli
Munc18-1/STXBP1 Protein, Human, Recombinant (His & GST)
TMPY-01820
Species: Human
Expression System: Baculovirus Insect Cells
Dystonin Protein, Human, Recombinant (His)
TMPH-01257
Species: Human
Expression System: P. pastoris (Yeast)
Munc18c/STXBP3 Protein, Human, Recombinant (His & GST)
TMPY-01960
Species: Human
Expression System: Baculovirus Insect Cells
CSNK1G1 Protein, Human, Recombinant (His & GST)
TMPY-04402
Species: Human
Expression System: Baculovirus Insect Cells
NCKIPSD Protein, Human, Recombinant (GST)
TMPY-03435
Species: Human
Expression System: E. coli
JAK2 Protein, Human, Recombinant (His)
TMPH-02274
Species: Human
Expression System: E. coli
カタログ番号 製品名
L1710 Anti-COVID-19 Compound Library

1133 compounds
A unique collection of 1133 compounds with confirmed anti-SARS-CoV-2 activity or potential activity and part of them are broad-spectrum antiviral agents;