検索結果

Search Results for " hydrase "

ターゲット

Carbonic Anhydrase Apoptosis PDE Carbonic Anhydrase

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	ターゲット
T77631	Enpp/Carbonic anhydrase-IN-2	Apoptosis , PDE , Carbonic Anhydrase
	Enpp/Carbonic anhydrase-IN-2 is a potent dual inhibitor of Enpp and carbonic anhydrase, inhibiting NPP1, NPP2, NPP3, CA-IX, CA-XII, with IC50 values of 1.13, 1.07, 0.74, 0.33, 0.68, respectively.Enpp/Carbonic anhydrase-I...	Apoptosis , PDE , Carbonic Anhydrase
T63305	Carbonic anhydrase inhibitor 6	Carbonic Anhydrase
	Carbonic anhydrase inhibitor 6 is a potent human carbonic anhydrase (hCA) inhibitor that inhibits hCA IX, hCA II, hCA XII, and hCA I. It is used in the study of diseases caused by abnormalities in carbonic anhydrase.	Carbonic Anhydrase
T67775	Enpp/Carbonic anhydrase-IN-1	PDE , Carbonic Anhydrase
	Enpp/Carbonic anhydrase-IN-1 (compound 1e) is a potent inhibitor of Enpp and carbonic anhydrase. Enpp/Carbonic anhydrase-IN-1 exhibits IC50s of 1.36, 1.35, 3.00, 0.88, 1.02 µM for NPP1, NPP2, NPP3, CA-II, CA-IX respectiv...	PDE , Carbonic Anhydrase
T61032	Carbonic anhydrase inhibitor 10
	Carbonic anhydrase inhibitor 10 can be used in the research of cancer that shows anti-proliferative activity against MCF-7 cancer cell line with an IC50 of 11.9 μM. Carbonic anhydrase inhibitor 10 is a potent inhibitor o...
T72164	Enpp/Carbonic anhydrase-IN-2
	Enpp/Carbonic anhydrase-IN-2 is a potent Enpp and carbonic anhydrase inhibitor with IC 50 s of 1.13, 1.07, 0.74, 0.33, 0.68 for NPP1, NPP2, NPP3, CA-IX, CA-XII respectively. Enpp/Carbonic anhydrase-IN-2 shows antiprolif...
T62976	Carbonic anhydrase inhibitor 5
	Carbonic anhydrase inhibitor 5 is a potent and selective inhibitor of human carbonic anhydrase (hCA), acting on hCA II (IC50: 42.9 nM), hCA IX (IC50: 47.6 nM) and hCA XII (IC50: 6.7 nM).
T76013	Carbonic anhydrase
	Carbonic anhydrase is ubiquitous zinc-containing metalloenzyme present in prokaryotes and eukaryotes. Carbonic anhydrase can catalyze reversible conversion of carbon dioxide to bicarbonate and protons. Carbonic anhydrase...
T61981	Human carbonic anhydrase II-IN-1
	Human carbonic anhydrase II-IN-1 (Compound S-13) is a potent human carbonic anhydrase II (hCA II) inhibitor. Human carbonic anhydrase II-IN-1 shows Kis of 4.4 nM, 9.2 nM, 480.2 nM and 14.7 nM for hCA II, I, IV and IX, re...
T63005	Carbonic anhydrase inhibitor 11
	Carbonic anhydrase inhibitor 11 (compound VI) is a potent, selective carbonic anhydrase inhibitor that acts on CA II (Ki: 40 nM), CA IX (Ki: 39 nM) and CA XII (Ki: 900 nM).
T61842	Carbonic anhydrase inhibitor 14
	Carbonic anhydrase inhibitor 14 (Compound 8b) is a potent CA inhibitor, exhibiting K i values of 1203, 99.7, 9.4, and 27.7 nM against hCA I, hCA II, hCA IX, and hCA XII, respectively. Additionally, it effectively inhibit...
T62666	Carbonic anhydrase inhibitor 7
	Carbonic anhydrase inhibitor 7 is a potent inhibitor of human carbonic anhydrase (hCA), acting on hCA IX (Ki: 6.5 nM), hCA II (Ki: 7.1 nM), hCA XII (Ki: 72.1 nM) and hCA I (Ki: 255.8 nM).
T83137	ALP/Carbonic anhydrase-IN-1	Carbonic Anhydrase
	Compound 1e, also known as ALP/Carbonic anhydrase-IN-1, is a dual inhibitor targeting both carbonic anhydrase (CA) isozymes II, IX, and XII, as well as alkaline phosphatase (ALP). It exhibits inhibitory IC50 values of 0....	Carbonic Anhydrase
T60848	Carbonic anhydrase inhibitor 3
	Carbonic anhydrase inhibitor 3 (compound 11g) is an inhibitor of carbonic anhydrase II that reduces the intraocular pressure in glaucomatous rabbits [1].
T78840	Carbonic anhydrase inhibitor 15	Carbonic Anhydrase
	Carbonic Anhydrase Inhibitor 15 (Compound 8), with an inhibitory constant (K_i) of 8.5 nM for hCA II, exhibits analgesic effects [1].	Carbonic Anhydrase
T63731	Carbonic anhydrase inhibitor 9
	Carbonic anhydrase inhibitor 9 is a potent inhibitor of carbonic anhydrase (CA) that acts on hCA II (Ki: 56.4 nM) and IX (Ki: 56.9 nM) and exhibits antiproliferative effects.
T61982	Human carbonic anhydrase II-IN-2
	Human carbonic anhydrase II-IN-24 (Compound R-13) is a potent human carbonic anhydrase (hCA) inhibitor. Human carbonic anhydrase II-IN-24 shows K i s of 60.7, 320.7, 2298, and 35.2 nM for hCA I, II, IV and IX, respective...
T61829	Carbonic anhydrase inhibitor 4
	Carbonic anhydrase inhibitor 4 is a photoprobe that inhibits the activity of carbonic anhydrase. It specifically targets human carbonic anhydrases, including hCA I-XIV, with K i values ranging from 640-1166 nM [1].
T61980	Carbonic anhydrase inhibitor 8
	Carbonic anhydrase inhibitor 8 (compound R-13) is a potent human carbonic anhydrase (hCA). Carbonic anhydrase inhibitor 8 shows K i values of 60.7 nM, 320.7 nM, 2298 nM for hCA I, hCA II, hCA IV, respectively.
T72122	Carbonic anhydrase inhibitor 12	Carbonic Anhydrase
	Carbonic Anhydrase Inhibitor 12 is a potent inhibitor of CA II, with additional inhibitory activity against CA I, exhibiting K_i values of 1.72 nM for CA II and 271 nM for CA I. Moreover, it demonstrates significant anti...	Carbonic Anhydrase
T61120	Carbonic anhydrase inhibitor 2
	Compound 7c, identified as carbonic anhydrase inhibitor 1, effectively inhibits carbonic anhydrase II. This inhibitor, also known as carbonic anhydrase inhibitor 3, lowers intraocular pressure in glaucomatous rabbits [1]...
T61952	Carbonic anhydrase inhibitor 13
	Carbonic anhydrase inhibitor 13 (compound 7) is a potent inhibitor of carbonic anhydrase (CA).

Compounds

Enpp/Carbonic anhydrase-IN-2

T77631

Synonym:

Target: Apoptosis, PDE, Carbonic Anhydrase

Carbonic anhydrase inhibitor 6

T63305

Synonym:

Target: Carbonic Anhydrase

Enpp/Carbonic anhydrase-IN-1

T67775

Synonym:

Target: PDE, Carbonic Anhydrase

Carbonic anhydrase inhibitor 10

T61032

Synonym:

Target:

Enpp/Carbonic anhydrase-IN-2

T72164

Synonym:

Target:

Carbonic anhydrase inhibitor 5

Human carbonic anhydrase II-IN-1

T61981

Synonym:

Target:

Carbonic anhydrase inhibitor 11

T63005

Synonym:

Target:

Carbonic anhydrase inhibitor 14

T61842

Synonym:

Target:

Carbonic anhydrase inhibitor 7

T62666

Synonym:

Target:

ALP/Carbonic anhydrase-IN-1

T83137

Synonym:

Target: Carbonic Anhydrase

Carbonic anhydrase inhibitor 3

T60848

Synonym:

Target:

Carbonic anhydrase inhibitor 15

T78840

Synonym:

Target: Carbonic Anhydrase

Carbonic anhydrase inhibitor 9

T63731

Synonym:

Target:

Human carbonic anhydrase II-IN-2

T61982

Synonym:

Target:

Carbonic anhydrase inhibitor 4

T61829

Synonym:

Target:

Carbonic anhydrase inhibitor 8

T61980

Synonym:

Target:

Carbonic anhydrase inhibitor 12

T72122

Synonym:

Target: Carbonic Anhydrase

Carbonic anhydrase inhibitor 2

T61120

Synonym:

Target:

Carbonic anhydrase inhibitor 13

T61952

Synonym:

Target:

カタログ番号	製品名	別名	ターゲット
TN1078	Seneciphylline		P450 , GST
	Seneciphylline, one of the hepatotoxic pyrolizidine alkaloids, has mutagenic activity in Drosophila and their transfer into rat milk.Seneciphylline can significantly increased the activities of epoxide hydrase and glutat...		P450 , GST

天然物製品

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-00690	Carbonic Anhydrase 9 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Carbonic Anhydrase 9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.5 kDa and the accession number is A0A0S2Z3D0.
TMPY-00694	Carbonic Anhydrase 12 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Carbonic Anhydrase 12 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.6 kDa and the accession number is O43570-1.
TMPY-00689	Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 67.7 kDa and the accession number is A0A0S2Z3D0.
TMPY-01735	Carbonic Anhydrase 2 Protein, Human, Recombinant (His)	Human	E. coli
	Carbonic Anhydrase 2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 30 kDa and the accession number is P00918.
TMPY-02990	Carbonic Anhydrase 9 Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
	Carbonic Anhydrase 9 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.1 kDa and the accession number is A0A8C0RHE4.
TMPH-03259	Carbonic Anhydrase 2 Protein, Rat, Recombinant (His)	Rat	E. coli
	Essential for bone resorption and osteoclast differentiation. Reversible hydration of carbon dioxide. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide abso...
TMPY-00693	Carbonic Anhydrase 10 Protein, Human, Recombinant	Human	HEK293 Cells
	Carbonic Anhydrase 10 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 27.2 kDa and the accession number is A0A384MTY8.
TMPY-02133	Carbonic Anhydrase VB Protein, Human, Recombinant (His)	Human	E. coli
	Carbonic anhydrase 5B, also known as carbonate dehydratase VB, carbonic anhydrase VB, CA-VB and CA5B, is amember of the alpha-carbonic anhydrase family. The strongest expression of CA5B / CA-VB is in heart, pancreas, ...
TMPY-01700	Carbonic Anhydrase 9 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Carbonic Anhydrase 9 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.3 kDa and the accession number is Q3UUZ9.
TMPY-01706	Carbonic Anhydrase 8 Protein, Human, Recombinant (His)	Human	E. coli
	Carbonic Anhydrase 8 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 33.8 kDa and the accession number is P35219.
TMPY-02301	Carbonic Anhydrase 8 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Carbonic Anhydrase 8 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.5 kDa and the accession number is P28651.
TMPY-06939	Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293 Cells
	Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 69.51 kDa and the accession number is NP_001207.2.
TMPY-06936	Carbonic Anhydrase 9 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Carbonic Anhydrase 9 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 44.23 kDa and the accession number is NP_001207.2.
TMPY-01761	Carbonic Anhydrase 3 Protein, Human, Recombinant (His)	Human	E. coli
	Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including re...
TMPJ-00731	Carbonic Anhydrase 1 Protein, Human, Recombinant (His)	Human	E. coli
	Carbonic Anhydrase 1 (CA1) is a cytosolic enzyme, belonging to the alpha-carbonic anhydrase family. It is highly expressed in erythrocytes and acts as an early marker for erythroid differentiation. Carbonic anhydrase 1 p...
TMPK-00524	CA9/Carbonic Anhydrase IX Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tu...
TMPK-00478	Carbonic Anhydrase 12 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues. Carbonic anhydrase XII (CA XII) is a key mediator of several signaling pathways that are involved in ...
TMPY-00967	Carbonic Anhydrase 14 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Carbonic Anhydrase 14 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the accession number is A8K3J4.
TMPJ-00701	Carbonic Anhydrase 11 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Carbonic Anhydrase-Related Protein 11 (CA11) is a secreted protein member of the α-carbonic anhydrase family. Carbonic Anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of ...
TMPJ-00283	Carbonic Anhydrase 9 Protein, Human, Recombinant (Avi & His), Biotinylated	Human	HEK293 Cells
	Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzym...
TMPY-02989	Carbonic Anhydrase 9 Protein, Canine, Recombinant (hFc)	Canine	HEK293 Cells
	Carbonic Anhydrase 9 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 67.6 kDa.
TMPY-02302	Carbonic Anhydrase 10 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Carbonic Anhydrase 10 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.1 kDa and the accession number is P61215.
TMPY-01351	Carbonic Anhydrase 10 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Carbonic Anhydrase 10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33 kDa and the accession number is A0A384MTY8.
TMPK-00283	CA9/Carbonic Anhydrase IX Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tu...
TMPY-00691	Carbonic Anhydrase 14 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Carbonic Anhydrase 14 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.2 kDa and the accession number is Q9WVT6.
TMPH-03258	Carbonic Anhydrase 1 Protein, Rat, Recombinant (His & SUMO)	Rat	E. coli
	Reversible hydration of carbon dioxide. Carbonic Anhydrase 1 Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.2 kDa and the acce...
TMPY-00688	Carbonic Anhydrase 12 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Carbonic Anhydrase 12 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.8 kDa and the accession number is Q8CI85.
TMPY-00513	Carbonic Anhydrase 4 Protein, Human, Recombinant (His)	Human	CHO Cells
	Carbonic Anhydrase 4 Protein, Human, Recombinant (His) is expressed in CHO mammalian cells with His tag. The predicted molecular weight is 31.7 kDa and the accession number is P22748-1.
TMPY-02111	Carbonic Anhydrase 2 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Carbonic Anhydrase 2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 30.4 kDa and the accession number is AAH55291.1.
TMPY-02277	Carbonic Anhydrase 7 Protein, Human, Recombinant (His)	Human	E. coli
	Carbonic anhydrase 7, also known as carbonate dehydratase VII, carbonic anhydrase VII, CA-VII and CA7, is a cytoplasm protein which belongs to thealpha-carbonic anhydrase family. Carbonic anhydrases are a large family...
TMPY-01327	Carbonic Anhydrase 4 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Carbonic Anhydrase 4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is Q64444.
TMPY-06944	Carbonic Anhydrase 12 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Carbonic Anhydrase 12 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 33.45 kDa and the accession number is NP_001209.1...