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Search Results for " leg "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T14176	Aleglitazar	RO0728804,R1439	PPAR
	Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively. Aleglitazar can be used for the research of type II diabetes.		PPAR
T76235	Peceleganan
	Peceleganan (PL-5), a synthetic hybrid peptide, combines cecropin A (1-10) and melittin B (3-18) sequences to form a (10+16)-peptide analogue with antimicrobial properties. This compound effectively inhibits wound infect...
T125013	(S)-(-)-Pulegone
	(S)-(-)-Pulegone is a useful organic compound for research related to life sciences and the catalog number is T125013.
T24849	TachypleginA-2	tA 2,tA-2,tA2
	TachypleginA-2 is a parasite motility and invasion inhibitor.
T65134	3-Indoleglyoxylic acid
	3-Indoleglyoxylic acid is a useful organic compound for research related to life sciences. The catalog number is T65134 and the CAS number is 1477-49-2.
T77016	Galegenimab
	Galegenimab (FHTR 2163; RG 6147; RO 7171009), an antibody fragment targeting High-temperature requirement A1 (HTRA1), is utilized in the research of age-related macular degeneration (AMD) [1].
T39905	Legumain inhibitor 1		Gamma-secretase
	Legumain inhibitor 1 is a highly potent and specific Legumain inhibitor with potential anticancer activity for cancer research.		Gamma-secretase
T76235L	Peceleganan acetate
	Peceleganan acetate (PL-5), a synthetic hybrid analogue combining segments of cecropin A (1-10) and melittin B (3-18) to form a (10+16)-peptide, demonstrates antimicrobial properties. It is specifically effective in inhi...
T33026	Lycophlegmarine
	Lycophlegmarine is a bioactive chemical.
T33027	Lycophlegmine
	Lycophlegmine is a bioactive chemical.
T32623	Legumin
	Legumin is a herbicide, which is a mixture of Embutone and Tropotox.
T25311	Desmethylselegiline
	Desmethylselegiline is an Enzyme Inhibitor.
T24848	TachypleginA	Tachyplegin A,Tachyplegin-A
	TachypleginA is a parasite motility and invasion inhibitor.
T125548	(-)Isopulegone
	(-)Isopulegone is a useful organic compound for research related to life sciences and the catalog number is T125548.
T19525L	PPA-904 FA	PPA-904 FA（30189-85-6 Free base）	Antibiotic
	PPA-904 FA is a cationic photosensitizer with broad-spectrum antimicrobial activity for use in photodynamic studies (PDT) studies of chronic leg ulcers and diabetic foot ulcers.		Antibiotic
T6647	Rotigotine-	Neupro,N-0923,N-0437,SPM 962	Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
	Rotigotine (N-0923) is a non-ergot dopamine receptor agonist used in the therapy of Parkinson disease and restless leg syndrome. Administered as a once-daily transdermal patch, Rotigotine has not been associated with ser...		Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
T6651L	Safinamide	EMD1195686,FCE26743,FCE 26743,EMD-1195686,EMD 1195686,FCE-26743	MAO
	Safinamide (FCE-26743) is a reversible and selective monoamine oxidase B (IC50 0.098μM) inhibitor, reducing the degradation of dopamine, and a glutamate release inhibitor (IC50 8μM). It also inhibits dopamine reuptake. S...		MAO
T38984	Z-Ala-Ala-Asn-AMC	Cbz-Ala-Ala-Asn-AMC,Z-Ala-Ala-Asn-AMC
	Z-Ala-Ala-Asn-AMC, also known as Cbz-Ala-Ala-Asn-AMC, serves as a substrate for legumain. The overexpression of legumain in 293 HEK-Leg cells results in efficient cleavage of Cbz-Ala-Ala-Asn-AMC.

Compounds

Aleglitazar

T14176

Synonym: RO0728804,R1439

Synonym: tA 2,tA-2,tA2

Target:

3-Indoleglyoxylic acid

Legumain inhibitor 1

T39905

Synonym:

Target: Gamma-secretase

Synonym: Tachyplegin A,Tachyplegin-A

Synonym: PPA-904 FA（30189-85-6 Free base）

Target: Antibiotic

Rotigotine-

T6647

Synonym: Neupro,N-0923,N-0437,SPM 962

Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor

Safinamide

T6651L

Synonym: EMD1195686,FCE26743,FCE 26743,EMD-1195686,EMD 1195686,FCE-26743

Target: MAO

Z-Ala-Ala-Asn-AMC

T38984

Synonym: Cbz-Ala-Ala-Asn-AMC,Z-Ala-Ala-Asn-AMC

Target:

カタログ番号	製品名	別名	ターゲット
T0070	Pentoxifylline	Oxpentifylline,PTX,BL-191	HIV Protease , PDE , Adenosine Receptor , Autophagy
	Pentoxifylline (PTX) modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodiesterase and affects blood rheology. It also inhibits platelet ...		HIV Protease , PDE , Adenosine Receptor , Autophagy
T3333	Cyclogalegenin	Cyclogalegigenin,Cyclogalagenin,Astramembrangenin,Cycloastragenol	Telomerase
	Cyclogalegenin (Astramembrangenin) is able to elongate telomeres, resulting in increased lifespan of the animals.		Telomerase
TCS0102	Pulegone	(+)-Pulegone	Calcium Channel , Endogenous Metabolite , TRP/TRPV Channel
	1. Pulegone ((+)-Pulegone) has cytotoxicity followed by regenerative cell proliferation is the MOA for Pulegone-induced urothelial tumors in female rats. 2. Pulegone induces a verapamil-sensitive psychostimulant effect t...		Calcium Channel , Endogenous Metabolite , TRP/TRPV Channel
Fr14207	(-)-Isopulegol		Others
	Isopulegol has antioxidant, and neuroactive properties. It also has gastroprotective effects induced by isopulegol appear to be mediated, at least in part, by endogenous prostaglandins, K+ATP channel opening and antioxid...		Others
TN4763	Phlegmanol C		Others
	Phlegmanol C is a natural product for research related to life sciences. The catalog number is TN4763 and the CAS number is 1260-05-5.		Others
T35532	Galegine hydrochloride
	Galegine hydrochloride, a guanidine derivative derived from G. officinalis, plays a role in inducing weight loss in mice and has contributed to the development of biguanides, including metformin and phenformin. This comp...
TN4322	Isopulegol		ATPase , Potassium Channel , GABA Receptor
	Isopulegol presents depressant- and anxiolytic-like effects, it also has anticonvulsant and bioprotective effects against PTZ-induced convulsions are possibly related to positive modulation of benzodiazepine-sensitive GA...		ATPase , Potassium Channel , GABA Receptor
TN6280	Aquilegiolide
	Aquilegiolide is a natural product for research related to life sciences. The catalog number is TN6280 and the CAS number is 94481-79-5.
T8275	(+)-Isopulegol		Parasite
	(+)-Isopulegol is a monoterpenoid from Mentha canadensis L.		Parasite

天然物製品

Pentoxifylline

T0070

Synonym: Oxpentifylline,PTX,BL-191

Target: HIV Protease, PDE, Adenosine Receptor, Autophagy

Cyclogalegenin

T3333

Synonym: Cyclogalegigenin,Cyclogalagenin,Astramembrangenin,Cycloastragenol

Target: Telomerase

Pulegone

TCS0102

Synonym: (+)-Pulegone

Target: Calcium Channel, Endogenous Metabolite, TRP/TRPV Channel

Galegine hydrochloride

Target: ATPase, Potassium Channel, GABA Receptor

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-00876	Legumain Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Legumain Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.8 kDa and the accession number is A2RTI3.
TMPH-02400	Pal Protein, Legionella pneumophila, Recombinant (His)	Legionella pneumophila	P. pastoris (Yeast)
	Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Very strongly associated with the peptidoglycan.
TMPH-03092	Leghemoglobin A Protein, Phaseolus vulgaris, Recombinant (His & Myc)	Phaseolus vulgaris	E. coli
	Provides oxygen to the bacteroids. This role is essential for symbiotic nitrogen fixation. Leghemoglobin A Protein, Phaseolus vulgaris, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and ...
TMPH-00434	Ovomucoid Protein, Coturnix delegorguei, Recombinant (His & Myc & SUMO)	Coturnix delegorguei	E. coli
	Ovomucoid Protein, Coturnix delegorguei, Recombinant (His & Myc & SUMO) is expressed in E. coli.
TMPH-03407	NIFH Protein, Rhizobium leguminosarum, Recombinant (GST & His & Myc)	Rhizobium leguminosarum	E. coli
	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein. NIFH Protein, Rhizobium leguminosarum, Recombinant (GST...
TMPH-03134	Leghemoglobin Lb120-8 Protein, Pisum sativum, Recombinant (His)	Pisum sativum	E. coli
	Provides oxygen to the bacteroids. This role is essential for symbiotic nitrogen fixation. Leghemoglobin Lb120-8 Protein, Pisum sativum, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The p...
TMPH-02402	Zinc metalloproteinase Protein, Legionella pneumophila, Recombinant (His)	Legionella pneumophila	E. coli
	Cleaves collagen, gelatin, casein, alpha-1-antitrypsin, and bovine insulin. May play a role in the pathogenesis of legionnaires disease.
TMPH-02399	Pal Protein, Legionella pneumophila, Recombinant (E. coli, His)	Legionella pneumophila	E. coli
	Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Very strongly associated with the peptidoglycan.
TMPH-02432	Legumain Protein, Cynomolgus, Recombinant (E. coli, His & Myc)	Cynomolgus	E. coli
	Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Requir...
TMPH-02398	ASA dehydrogenase Protein, Legionella pneumophila, Recombinant (His)	Legionella pneumophila	E. coli
	Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
TMPH-02401	RplL Protein, Legionella pneumophila, Recombinant (His & Myc)	Legionella pneumophila	E. coli
	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation. rplL Protein, Legionella pneumophila, Recombinant (His & Myc) is express...
TMPH-02431	Legumain Protein, Cynomolgus, Recombinant (His & Myc)	Cynomolgus	Baculovirus Insect Cells
	Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Requir...
TMPY-02873	Legumain Protein, Sus scrofa (Pig), Recombinant (His)	Sus scrofa (Pig)	HEK293 Cells
	Legumain Protein, Sus scrofa (Pig), Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.7 kDa and the accession number is A0A287AW67.
TMPH-00772	Leghemoglobin C2 Protein, Glycine max, Recombinant (His)	Glycine max	E. coli
	Provides oxygen to the bacteroids. This role is essential for symbiotic nitrogen fixation.
TMPY-06640	Legumain Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Legumain Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.12 kDa and the accession number is Q99538.
TMPH-02397	MIP Protein, Legionella longbeachae, Recombinant (His & Myc)	Legionella longbeachae	E. coli
	Essential virulence factor associated with macrophage infectivity. Exhibits PPIase activity.