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T13491 |
Neuromuscular-targeting compound 1
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Others
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Neuromuscular-targeting compound 1 can be used to study muscular dystrophy and neuromuscular-related diseases. |
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T10059 |
Neuromuscular Disorder-Targeting Compound 1
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Others
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Neuromuscular Disorder-Targeting Compound 1 is a compound used in the research of neuromuscular disorders, for example, symptoms of chronic fatigue syndrome and fibromyalgia syndrome. |
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T0166 |
Pancuronium dibromide
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Pancuronium bromide,Pavulon |
AChR
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Pancuronium dibromide (Pavulon), a competitive AChR antagonist (IC50 = 5.5 nM), acts as a skeletal muscle relaxant. Pancuronium dibromide(Pancuronium bromide) blocking neuromuscular transmission is achieved by competing ... |
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T1234 |
5,5-Dimethyloxazolidine-2,4-dione
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Dimethadion,Dimethadione,Dimethyloxazolidinedione |
Calcium Channel
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5,5-Dimethyloxazolidine-2,4-dione (Dimethadione) is an anticonvulsant that is the active metabolite of TRIMETHADIONE. |
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T5326 |
Sugammadex sodium
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Org25969,Sugammadex (sodium) |
Others
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Sugammadex sodium (Org25969) , a synthetic derivative of γ-cyclodextrin, is a steroid-based neuromuscular blocker reversing agent. |
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T21793 |
CGP 35348
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GABA Receptor
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CGP 35348 is a selective antagonist of GABAB receptor (EC50 = 34 μM). CGP 35348 can be used in studies of neuromuscular coordination and spatial learning after neonatal brain damage in albino mice. |
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T2227 |
Hemicholinium 3
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Hemicholinium-3,Hemicholine |
Others
,
AChE
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Hemicholinium 3 is a potent and selective choline uptake blocker. |
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T6397 |
Atracurium besylate
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Tracrium,51W89,BW-33A |
AChR
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Atracurium besylate (51W89) is a non-depolarizing neuromuscular blocking agent with short duration of action. Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for eliminat... |
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T22371 |
Mivacurium dichloride
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Mivacurium chloride |
AChR
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Mivacurium dichloride (Mivacurium chloride) is a non-depolarising, rapid neuromuscular blocker of short duration, used therefore as anesthetic, to provide skeletal muscle relaxation in minor surgical operations, in emerg... |
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T4497 |
Amifampridine
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3,4-Pyridinediamine,Pyridine-3,4-Diamine,3,4-Diaminopyridine |
Others
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Amifampridine (3,4-Diaminopyridine) is predominantly in the treatment of a number of rare muscle diseases. Amifampridine works by blocking potassium channel efflux in nerve terminals so that action potential duration is ... |
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T0818 |
Decamethonium bromide
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Decacuran,Syncurine |
AChR
,
AChE
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Decamethonium bromide (Syncurine) is a neuromuscular blocker and nicotinic AChR partial agonist. |
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T12481 |
Pipecuronium bromide
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RGH-1106 |
AChR
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Pipecuronium bromide (RGH-1106) is a selective and potent nAChR antagonist that also acts as a non-depolarising steroidal neuromuscular blocker, causing muscle relaxation, often in conjunction with antibiotics. |
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TP1868 |
Proctolin
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Others
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Proctolin is a bioactive neuropeptide that modulates interneuronal and neuromuscular synaptic transmission in a wide variety of arthropods. |
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T6684 |
Succinylcholine Chloride Dihydrate
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choline chloride succinate,Succinyldicholine dichloride,Suxamethonium Chloride Dihydrate |
AChR
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Succinylcholine Chloride Dihydrate (Succinyldicholine dichloride) is a nicotinic AChR agonist and also acts as a depolarizing neuromuscular blocker. |
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T1259 |
Pyrantel pamoate
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Pyrantel embonate |
Others
,
Antibiotic
,
Parasite
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Pyrantel pamoate (Pyrantel embonate) is a depolarizing neuromuscular blocking agent. |
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T3966 |
Tirasemtiv
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CK-2017357 |
Others
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Tirasemtiv (CK-2017357)(CK 2017357) is a small-molecule fast-skeletal-troponin activator, with a potential treatment for muscle weakness and neuromuscular dysfunction. |
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T1594 |
Vecuronium bromide
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ORG NC 45 |
AChR
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Vecuronium bromide (ORG NC 45) is a synthetic, intermediate-acting mono-quaternary steroid and non-depolarizing neuromuscular blocking agent, with muscle relaxant activity. |
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T14094 |
Acetamiprid
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AChR
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Acetamiprid is a nicotinic acetylcholine receptor (nAChR) agonist. Acetamiprid is a neonicotinoid insecticide used worldwide. It is shown to be associated with neuromuscular and reproductive disorders. |
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T20344 |
Acetylcholine bromide
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Others
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Acetylcholine bromide is the bromide salt of acetylcholine. It is an neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, a... |
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T0954 |
Halothane
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Narcotane,Anestan |
Potassium Channel
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Chloride channel
,
GABA Receptor
,
NMDAR
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Halothane (Anestan) is a nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. NITROUS OXIDE is often given concomitantly.... |
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T0156 |
Rocuronium bromide
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ORG 9426,ORG 9426 (Bromide) |
AChR
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Rocuronium bromide (ORG 9426) is a muscle relaxant or aminosteroid non-depolarizing neuromuscular blocker. During surgery or mechanical ventilation, it is used to facilitate endotracheal intubation and to provide skeleta... |
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T77445 |
Apitegromab
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SRK-015 |
Opioid Receptor
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Apitegromab (SRK-015) is a new myostatin inhibitor, an antibody targeting myostatin precursor, which can be used to study neuromuscular diseases including spinal muscular atrophy. |
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TP1253 |
Argireline
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Acetyl hexapeptide-3 |
Others
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Argireline (Acetyl hexapeptide-3) is composed of chains of amino acids known as peptides. Argireline significantly inhibits Ca2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argirelin... |
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T0077 |
Dantrolene sodium
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Lapatinib ditosylate monohydrate,Dantrolene sodium salt |
Others
,
Calcium Channel
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Dantrolene sodium (Lapatinib ditosylate monohydrate) salt is a skeletal muscle relaxant and can interfere with excitation-contraction coupling in the muscle fiber. It is used for the treatment of spasticity and other neu... |
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T12748 |
Rocuronium
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Org-9426 |
Others
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Rocuronium is an blocker of aminosteroid non-depolarizing neuromuscular. |
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T26672 |
Astromicin Sulfate
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A-44747,A 44747,A44747 |
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Astromicin Sulfate is an antibiotic with aminoglycoside structure. Astromicin Sulfate may produce depression of neuromuscular function. |
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T24057 |
Fazadinium bromide
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Fazadinium bromide is a muscle relaxant. It acts as a nicotinic acetylcholine receptor antagonist through the neuromuscular blockade. |
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T31296 |
Decamethonium chloride
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Decamethylenebis(trimethylammonium chloride),Decamethonium dichloride |
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Decamethonium is a depolarizing muscle relaxant or neuromuscular blocking agent,[1] and is used in anesthesia to induce paralysis. |
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T33721 |
Norcoralydine
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S-(-)-Xylopinine,l-Xylopinine,NSC 23898,NSC-23898,NSC23898 |
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Norcoralydine is a neuromuscular blocking agent. |
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T23960 |
Dacuronium
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UNII-VD6L56ZVX1,17-Hydroxypancuronium,Androstane, piperidinium deriv |
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Dacuronium is a new steroidal drug of neuromuscular blocking properties. Dacuronium produced a competitive type of neuromuscular block with a potency of approximately one-tenth that of tubocurarine and one-fiftieth that ... |
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T13908 |
SZ1676
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Others
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SZ1676 is a derivative of SZ1677, which is an agent of neuromuscular blocking. |
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T69425 |
Metocurine chloride
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Metocurine is a muscle relaxant through neuromuscular blockade. It is excreted entirely through the kidneys and therefore should not be used in patients with kidney failure. |
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T30079 |
ANQ-9040
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ANQ-9040 is a nondepolarizing neuromuscular relaxant of the steroid class. |
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TP2218 |
α-Conotoxin EI
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Others
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Selective antagonist of neuromuscular nicotinic receptors α1β1γδ |
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T25636 |
Laudexium
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Laudexium ion,Laudexium cation |
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Laudexium is a neuromuscular blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs. It is used adjunctively in surgical anesthesia to facilitate endotracheal intubatio... |
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T21099 |
Decamethonium iodide
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Decamethonium iodatum,Decamethonium diiodide,Dekamethoniumjodid |
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Decamethonium is a neuromuscular blocking agent or depolarizing muscle relaxant, and is used in anesthesia to induce paralysis. |
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T32870 |
Lophotoxin
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Lophotoxin belongs to the cembrene class of diterpenoids; neuromuscular toxin isolated from several pacific gorgonians of the genus Lophogorgia. |
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T25683 |
Leucomyosuppressin
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p-Glu-asp-val-asp-his-val-phe-leu-arg-phe-NH2 |
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Leucomyosuppressin, isolated from head extracts of the cockroach Leucophaea maderae, inhibits evoked transmitter release at the mealworm neuromuscular junction. |
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T23961 |
Dacuronium bromide
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NB 68,ORG 6368,NB68,Dacuronii bromidum |
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Dacuronium bromide is an aminosteroid neuromuscular blocking agent Pancuronium. It acts as a competitive antagonist of the nicotinic acetylcholine receptor. |
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T0818L |
Decamethonium
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Decamethonium (Syncurine) is a depolarizing muscle relaxant or neuromuscular blocking agent, and is used in anesthesia to induce paralysis. |
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T0395L |
Pyrantel
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Strongid,Pyrantelum,Pyrequan,Pin-X,Pirantele |
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Pyrantel is a nicotinic receptor agonist and a depolarizing neuromuscular-blocking agent, that causes persistent nicotinic activation resulting in spastic paralysis of susceptible nematodes. |
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T32066 |
Hexafluronium Bromide
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Mylaxen,Hexafluorenium bromide,Milaxen,Hexafluorenium dibromide,Esafluronio bromuro |
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Hexafluronium bromide is a neuromuscular blocker and nicotinic acetylcholine receptor antagonist used in anesthesiology to prolong and enhance the skeletal muscle relaxation of succinylcholine during surgery. |
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T26230 |
Stilbamidine dihydrochloride
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NSC 35605,NCI 174 |
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Stilbamidine dihydrochloride is a blocker of neuromuscular transmission and axonal conduction used to study the distribution of the drug in the organs and tissues of rats following intravenous injection. |
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T25637 |
Laudexium methylsulfate
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Laudexium,Laudolissin methosulphate |
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Laudexium methylsulfate is a neuromuscular blocking drug or skeletal muscle relaxant. It is used adjunctively in surgical anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during ... |
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T68783 |
Stercuronium
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Stercuronium is an aminosteroid neuromuscular blocking agent which was never marketed. It acts as a competitive antagonist of the nicotinic acetylcholine receptor, and is also reported to be an acetylcholinesterase inhib... |
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T75283 |
Atracurium
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|
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Atracurium (BW-33A free acid) is a potent, competitive, non-depolarizing neuromuscular blocking agent and an AChR receptor antagonist. It induces bronchoconstriction and neuromuscular blockade, in addition to promoting a... |
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T16814 |
RX 67668
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Others
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RX 67668 is a muscle relaxant used to relieve skeletal muscle fatigue. RX 67668 is an effective cholinesterase inhibitor (IC50: 5 μM for both acetylcholinesterase and butyrylcholinesterase). RX 67668 can reverse the neur... |
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T37702 |
Pancuronium (bromide hydrate)
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|
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Pancuronium is an aminosteroid antagonist of muscle-type nicotinic acetylcholine receptors (nAChRs) with an IC50value of 14.8 nM using patch clamp electrophysiology in BOSC23 cells expressing mouse nAChRs.1It acts as a n... |
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TP2407 |
Small cardioactive peptide A
|
SCPA |
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Small cardioactive peptide A, as a neuropeptide that modulates neuromuscular synapsis in Aplysia, can also function as a neural cotransmitter in molluscs and exert a role in both the central and peripheral modulation of ... |
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T74690 |
Monarsen
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Monarsen (EN101), a synthetic 20-base antisense oligodeoxynucleotide targeting the human AChE gene, is utilized in researching autoimmune myasthenia gravis (MG). This neuromuscular disorder is characterized by autoantibo... |
