| T2S2382 |
3'-Hydroxypterostilbene
|
3'-HPT |
Apoptosis
,
Autophagy
|
|
3'-Hydroxypterostilbene (3'-HPT), a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells with IC50s of 9.0, 40.2, and 70.9 μM for COLO 205, HCT-116, and HT-29 cells, respectively, b... |
| T4S2063 |
Tetrahydrocoptisine
|
STYLOPINE |
ERK
,
p38 MAPK
,
NF-κB
|
|
1. Tetrahydrocoptisine (STYLOPINE) has effective effects in suppressing inflammation. 2. Tetrahydrocoptisine possesses a protective effect on LPS-induced ALI through inhibiting of NF-κB signaling pathways, which may invo... |
| T2836 |
Isorhamnetin
|
3-methylquercetin,3'-Methylquercetin,Isorhamnetol,3'-Methoxyquercetin |
MEK
,
PI3K
,
Endogenous Metabolite
|
|
Isorhamnetin (3-methylquercetin) is the methylated metabolite of quercetin. Quercetin is an important dietary flavonoid with in vitro antioxidant activity. Isorhamnetin prevents endothelial cell injuries from oxidized LD... |
| T23774 |
Bauerenol
|
NSC 147745,Baurenol |
|
|
Bauerenol is a triterpenoid from Indian Suregada angustifolia. It also induces reactive oxygen species-mediated P38MAPK activation and apoptosis in human hepatocellular carcinoma cells. |
| TN1211 |
2-Hydroxy-3-methylanthraquinone
|
|
ERK
,
p38 MAPK
,
Caspase
|
|
2-Hydroxy-3-methylanthraquinone enhances apoptosis of U937 cells,in part,through activation of p-p38MAPK and downregulation of p-ERK1/2; triggers caspase-3 activation mediated apoptotic induction. |
