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天然化合物

カタログ番号	製品名	別名	ターゲット
T68102	Mitoquidone		Others
	Mitoquidone, a novel pentacyclic pyrroloquinone, is a potential anticancer agent. Mitoquidone showed good activity in a range of experimental solid tumour models and did not exhibit significant cytotoxicity.		Others
T32566	Lantanolic acid
	Lantanolic acid is a pentacyclic triterpenoid from the leaves of Lantana montevidensis.
T37038	Betulinic Acid propargyl ester
	Betulinic acid propargyl ester is a pentacyclic lupane triterpene and alkyne derivative of betulinic acid .1,2It has been used in click chemistry reactions for the synthesis of cytotoxic anticancer betulinic acid derivat...
T38088	28-Deoxybetulin methyleneamine
	28-Deoxybetulin methyleneamine is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin .1It has been used in the synthesis of triterpene derivatives with antiviral activity. 1.Nitz,...
T37782	2,3-Indolobetulonic Acid
	2,3-Indolobetulonic acid is pentacyclic triterpenoid derivative of betulonic acid and an inhibitor of α-glucosidase (IC50= 1.8 μM).1 1.Khusnutdinova, E.F., Smirnova, I.E., Kazakova, O.B., et al.Synthesis and evaluation o...
T37781	2,3-Indolobetulin
	2,3-Indolobetulin is a pentacyclic triterpenoid and derivative of betulin .1It has been used in the synthesis of α-glucosidase inhibitors. 1.Khusnutdinova, E.F., Smirnova, I.E., Kazakova, O.B., et al.Synthesis and evalua...
T35678	2,3-Indolobetulinic glycine amide
	2,3-Indolobetulinic glycine amide is a pentacyclic triterpene and derivative of betulinic acid .1It has been used in the synthesis of betulinic acid derivatives with anticancer activity. 1.Kumar, V., Rani, N., Aggarwal, ...
T35693	N-(2-Azidoethyl)betulonamide
	N-(2-Azidoethyl)betulonamide is a pentacyclic triterpenoid, a derivative of betulonic acid , and an intermediate in the synthesis of betulonic acid derivatives within vitrocancer cell cytotoxicity.1 1.Suman, P., Patel, A...
T25000	Acetylaleuritolic acid	NSC 266221,NSC-266221,NSC266221
	Acetylaleuritolic acid is a pentacyclic triterpenoid, plant metabolite isolated from the leaves of Garcinia miniata. It has antitumor properties, showing tumor inhibitory activity in tests against P-388 lymphoblastic leu...
T37039	Betulinic Aldehyde oxime
	Betulinic aldehyde oxime is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin .1It is active againstE. aerogenes,E. coli,E. faecalis,P. aeruginosa,S. aureus, andC. albicans, as w...
T63061	Anti-inflammatory agent 13
	Anti-inflammatory agent 13 is a pentacyclic triterpene compound with a significant inhibitory effect on inflammation models. anti-inflammatory agent 13 has the potential to be used in studies of DAMP or PAMP-induced infl...
T63092	Anti-inflammatory agent 12
	Anti-inflammatory agent 12 is a pentacyclic triterpene compound that showed a significant bias in LPS-induced inflammatory responses (IC50: 2.22 μM). anti-inflammatory agent 12 has potential for use in inflammatory disea...
T69244	Betulonaldehyde
	Betulonaldehyde is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin that has been found in Betula. It is active against P. falciparum (IC50 = 3.36 µg/ml) and cytotoxic to NCI H1...

Compounds

Betulinic Acid propargyl ester

T37038

Synonym:

Target:

28-Deoxybetulin methyleneamine

T38088

Synonym:

Target:

2,3-Indolobetulonic Acid

2,3-Indolobetulinic glycine amide

T35678

Synonym:

Target:

N-(2-Azidoethyl)betulonamide

T35693

Synonym:

Target:

Acetylaleuritolic acid

T25000

Synonym: NSC 266221,NSC-266221,NSC266221

Target:

Betulinic Aldehyde oxime

T37039

Synonym:

Target:

Anti-inflammatory agent 13

T63061

Synonym:

Target:

Anti-inflammatory agent 12

カタログ番号	製品名	別名	ターゲット
T2S0501	Ilexgenin A		IL Receptor , TNF
	Ilexgenin A is a novel pentacyclic triterpenoid, is a compound extracted from leaves of Ilex hainanensis Merr		IL Receptor , TNF
TN2097	Pomolic acid		Apoptosis , Caspase , HIV Protease , AMPK
	Pomolic acid has anti-cancer, anti-inflammatory and apoptotic activities, it can induce apoptosis in SK-OV-3 cells, which is mediated by the mitochondrial-mediated intrinsic and death receptor-induced extrinsic pathways.		Apoptosis , Caspase , HIV Protease , AMPK
TN6722	Terminolic acid	2α,6β,23-trihydroxyl oleanolic acid	Antibacterial
	Terminolic acid (2α,6β,23-trihydroxyl oleanolic acid) is a pentacyclic triterpenoid glucoside isolated from Combretum racemosum, can inhibit the pro-inflammatory cytokines by binding to receptor active site of IL-1β and ...		Antibacterial
T21820	Resistomycin	Geliomycin,Heliomycin	Antibiotic
	Resistomycin (Geliomycin), a pentacyclic polyketide antibiotic, exhibits potent anticancer properties by triggering apoptosis.		Antibiotic
T0722	Ursolic acid	Malol,Urson,NSC 167406,NSC-4060,Prunol	Endogenous Metabolite , Autophagy
	Ursolic acid (Prunol)(Bungeolic acid), a natural pentacyclic triterpenoid carboxylic acid, shows anti-tumor effects.		Endogenous Metabolite , Autophagy
TN1866	Licoricesaponin G2
	Licoricesaponin G2 is a pentacyclic triterpenoid derived from Glycyrrhiza aspera, which can be used to differentiate crude liquorice from honey-processed liquorice.
T2813	Madecassoside	Asiaticoside A	Apoptosis , Antioxidant , Endogenous Metabolite
	Madecassoside (Asiaticoside A) is a pentacyclic triterpene extracted from Centella asitica (L.) with anti-inflammatory, anti-oxidative and anti-aging activities.		Apoptosis , Antioxidant , Endogenous Metabolite
TN1111	Arnidiol		Immunology/Inflammation related
	Arnidiol has anti-inflammatory activity, it possesses marked inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice.		Immunology/Inflammation related
T3323	Ursonic Acid	CCRIS 7123,NSC4060,Prunol,3-Ketoursolic acid,Malol,TOS-BB-0966	Apoptosis , HIV Protease , Endogenous Metabolite
	Ursonic Acid (TOS-BB-0966) belongs to the family of Ursane Triterpenes whose structure is based on the pentacyclic ursane skeleton. It has potential as HIV-1 Protease Inhibitor.		Apoptosis , HIV Protease , Endogenous Metabolite
T3368	Alpha-Hederin	Helixin,Tauroside E,α-Hederin,Hederoside C	Apoptosis , Others
	Alpha-Hederin (Tauroside E) is a water-soluble pentacyclic triterpenoid saponin found in the seeds of Nigella sativa, with hemolytic and apoptotic properties.		Apoptosis , Others
T3248	Alpha-Boswellic acid	α-Boswellic acid	Others
	alpha-Boswellic acid (α-Boswellic acid) is a pentacyclic triterpenoid natural product extracted from frankincense and has anticonvulsant and anticancer effects. In animals, it prevents and reduces Alzheimer's disease mar...		Others
T2830	Betulinic acid	ALS-357,Lupatic acid,Betulic acid	Apoptosis , Mitophagy , NF-κB , HIV Protease , Topoisomerase , Endogenous Metabolite , Aminopeptidase , Autophagy
	Betulinic acid (ALS-357) is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) which has antiretroviral, antimalarial, and anti-inflammatory propert...
T24884	Tingenone	Maytenin,Maitenin,Tingenin A,Tingenon
	Tingenone is a pentacyclic triterpene. It induces peripheral antinociception due to opioidergic activation.
T13964	Waltonitone		Others
			Others
T19880	Friedelinol	Friedelan-3alpha-ol,Friedelan-3-ol,NSC 407041,epi-Friedelinol,Epifriedelanol
	Friedelinol is a pentacyclic trierpene plant as the free acid or the aglycone for many saponins. Friedelinol can rearrange to the isomer, ursolic acid, or be oxidized to taraxasterol and amyrin.
T72867	Fusarisetin A
	Fusarisetin A, a pentacyclic fungal metabolite, is an acinar morphogenesis inhibitor .
T82747	Centellasaponin A
	Centellasaponin A (compound 10), a pentacyclic triterpene saponin, has been isolated from the methanolic extract of Centella asiatica [1].
T82042	Isoasiaticoside
	Isoasiaticoside, a pentacyclic triterpene saponin derived from Centella asiatica, exhibits potential neuroprotective effects in the 6-OHDA-induced PC12 cell model [1].
T82431	Eupenifeldin
	Eupenifeldin, a pentacyclic bistropolone isolated from Eupenicillium brefeldianum ATCC 74184, exhibits cytotoxic activity against the HCT-116 cell line and holds potential for leukemia research [1].