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Search Results for " piperazine "

ターゲット

111

阻害剤

2

天然化合物

1

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T12186 Navitoclax-piperazine ABT-263-piperazine BCL , Ligands for Target Protein for PROTAC
Navitoclax-piperazine (ABT-263-piperazine) is an inhibitor of B-cell lymphoma extra large (BCL-XL).
T28882 Sultosilic acid, piperazine salt A-585,Mimedran,piperazine-sultosylate,A585,A 585
Sultosilic acid piperazine salt is a drug with lowering lipid activity. It causes significant shortening of the euglobulin lysis time and a significant diminution of platelet adhesiveness, as well as statistically signif...
T21569 1-(1-Naphthyl) piperazine hydrochloride 1-naphthalen-1-ylpiperazine hydrochloride,1-(Naphthalen-1-yl)piperazine hydrochloride Others
1-(1-Naphthyl) piperazine hydrochloride (1-naphthalen-1-ylpiperazine hydrochloride) is a serotonergic ligand which could bind nonselectively with multiple serotonin (5-HT) receptors.
T8582 1-[(5-methylisoxazol-3-yl)methyl]piperazine Piperazine, 1-[(5-methyl-3-isoxazolyl)methyl]- (9CI) P2Y Receptor
1-[(5-methylisoxazol-3-yl)methyl]piperazine (Piperazine, 1-[(5-methyl-3-isoxazolyl)methyl]- (9CI)) is a P2Y12 inhibitor.
T7146 Piperazine adipate Parasite
Piperazine adipate is a potent broad spectrum anthelmintic.
T16540 Piperazine Erastin Ferroptosis
Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.
T16539 Piperazine citrate GABA Receptor
Piperazine citrate, an organic compound, consists of a six-membered ring, containing two nitrogen atoms at opposite positions in the ring. It used as an Anthelmintic.
T50018 1-(3-chloropyridin-2-yl)piperazine 2HCl Others
1-(3-chloropyridin-2-yl)piperazine dihydrochloride is a piperazine analog often used as a reagent in organic synthesis, as a ligand in coordination chemistry, and as a drug in pharmaceuticals. It is an inhibitor of DPP4,...
T5105 1-(2-Pyridyl)piperazine NSC13778 Adrenergic Receptor
1-(2-Pyridyl)piperazine (NSC-13778) is a selective α2-adrenoceptor antagonists. 1-(2-Pyridyl)piperazine shows sympatholytic activity. 1-(2-Pyridyl)piperazine is also a metabolite of Azaperone.
T0615 1-(3-Chlorophenyl)piperazine hydrochloride M-CPP hydrochloride Others
1-(3-Chlorophenyl)piperazine hydrochloride (M-CPP hydrochloride) is used for the synthesis of trazodone, Etoperidone, Nefazodone, etc.
T40034 GNF-8625 monopyridin-N-piperazine hydrochloride Trk receptor
GNF-8625 monopyridin-N-piperazine hydrochloride is a protomyosin receptor kinase (TRK) inhibitor.
T60231 N-[2-nitro-4-(trifluoromethyl)phenyl]piperazine Others
N-[2-nitro-4-(trifluoromethyl)phenyl]piperazine is a biologically active compound belonging to the piperazine group. It is an important synthetic intermediate used in the preparation of a wide range of drugs, agrochemica...
T50034 1-{1H-pyrrolo[2,3-d]pyrimidin-4-yl}piperazine 2HCl Others
1-{1H-pyrrolo[2,3-d]pyrimidin-4-yl}piperazine dihydrochloride (1-PPZ-DHC) is a compound used as a molecular structural unit. It is an analog of the natural product piperazine and has a wide range of biological activities...
T9876 1-(4-fluorophenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]Piperazine Others
Piperazine,1-(4-fluorophenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]- is a piperazine derivative with anti-SARS-CoV-2 activity.
T40111L BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride PD-1/PD-L1
BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride is a resorcinol di-Ph ether scaffold-based programmed cell death-1 (PD-1)/programmed cell death ligand 1 (PD-L1) inhibitor that inhibits the PD-1/PD-L1 interaction wi...
T39895 Thalidomide-Piperazine-PEG3-NH2 Thalidomide-Piperazine-PEG3-NH2
Thalidomide-Piperazine-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that combines the Thalidomide-based cereblon ligand with a linker commonly used in PROTAC technology, serving as an E3 ligase recruiter.
T39893 Thalidomide-Piperazine-PEG2-NH2 Thalidomide-Piperazine-PEG2-NH2
Thalidomide-Piperazine-PEG2-NH2 is a synthetic E3 ligase ligand-linker conjugate that combines the cereblon ligand derived from Thalidomide with a linker commonly utilized in PROTAC technology.
T50020 1-(1-phenyltetrazol-5-yl)piperazine HCl 1-(1-phenyl-1H-1,2,3,4-tetrazol-5-yl)piperazine hydrochloride Others
1-(1-phenyltetrazol-5-yl)piperazine;hydrochloride (1-(1-phenyl-1H-1,2,3,4-tetrazol-5-yl)piperazine hydrochloride) is a chemical derivative of piperazine that has been used as a starting material for the synthesis of othe...
T67739 BMY-14802 alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol Sigma receptor
BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.
T39711 Thalidomide-Piperazine-Piperidine
Thalidomide-Piperazine-Piperidine is a compound composed of a synthesized E3 ligase ligand-linker conjugate. It combines a cereblon ligand derived from Thalidomide with a linker commonly used in PROTAC technology.
T40645 PIPES 1,4-Piperazinediethanesulfonic acid,1,4-piperazine bis(ethanesulfonic acid),1,4-Piperazinebis(ethanesulfonic acid),PIPES Others
PIPES (1,4-Piperazinediethanesulfonic acid) serves as a crucial component of the buffering agent in biochemical applications, known as PIPES buffer.
T39697 Thalidomide-piperazine-Boc
Thalidomide-piperazine-Boc is an intermediate utilized for synthesizing BCL6 PROTAC, which targets B-cell lymphoma 6 protein.
T34069 Piperazine sebacate Nematorazine
Piperazine sebacate has anthelminthic activity. it be studie for therapy of trichocephalosis.
T70097 Acefylline piperazine
Acefylline piperazine is a stimulant drug of the xanthine chemical class. It acts as an adenosine receptor antagonist. Acephylline piperazine is a theophylline derivative with a direct bronchodilator action. It has the a...
T39696 Thalidomide-Piperazine 5-fluoride
Thalidomide-Piperazine 5-fluoride is a compound developed by synthesizing an E3 ligase ligand-linker conjugate. It incorporates a cereblon ligand derived from Thalidomide and utilizes a linker commonly employed in PROTAC...
T40231 Thalidomide-Piperazine-Piperidine hydrochloride
Thalidomide-Piperazine-Piperidine hydrochloride is a synthesized compound that serves as an E3 ligase ligand-linker conjugate. It combines the cereblon ligand derived from Thalidomide with a linker commonly used in PROTA...
T37373 4-hydroxy-3-Methoxyphenylglycol (piperazine salt)
4-hydroxy-3-Methoxyphenylglycol (piperazine salt) is a metabolite of norepinephrine derived in part by deamination of normetanephrine or by O-methylation of dihydroxyphenylglycol after cellular uptake of either intermedi...
T64340 ML267 4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide trifluoroacetate Others
ML267 (4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide trifluoroacetate) is a potent inhibitor of bacterial phosphopantetheinyl transferase that attenuates secondary meta...
T16277 NCT-502 N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide Dehydrogenase
NCT-502 (N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor, cytotoxic to PHGDH-dependent cancer cells. It decreases glucose-d...
T34935 Triclofenol piperazine CI 416,Triclofenol piperazina,CI-416,CI416,Triclofenol piperazate
Triclofenol piperazine helps with the treatment of patients imfected with parasite such as hookworms.
T40111 BMS-1166-N-piperidine-CO-N-piperazine
BMS-1166-N-piperidine-CO-N-piperazine is a chemical compound that contains a PD-1/PD-L1 immune checkpoint ligand and a PROTAC linker. It can be utilized in the synthesis of PROTAC PD-1/PD-L1 degrader-1, which effectivel...
T62461 Benzyl-piperazine-CO-benzothiazole-4-methylpiperidine Others
Benzyl-piperazine-CO-benzothiazole-4-methylpiperidine can be used to alter eukaryotic lifespan.
T77598 Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine (4-(4-methoxyphenyl)piperazin-1-yl)(2-(4-methylpiperidin-1-yl)benzo[d]thiazol-6-yl)methanone Others
Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine ((4-(4-methoxyphenyl)piperazin-1-yl)(2-(4-methylpiperidin-1-yl)benzo[d]thiazol-6-yl)methanone) is a raw material for biosynthesis and can be used to synthesiz...
T20999 1-(2,3-Dichlorphenyl)-piperazine DCPP Others
1-(2,3-Dichlorphenyl)-piperazine (DCPP) is a potent DHCR7 inhibitor. DHCR7 is the last enzyme in cholesterol biosynthesis.
T32187 Ipexidine mesylate Guanidino propyl piperazine,UNII-CI8CT0864P
Ipexidine mesylate is a bio-active chemical.
T67903 11β-HSD1 inibitor 17 Dehydrogenase
11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).
T65396 Piperazine 2HCl
Piperazine (2HCl) is gamma-aminobutyric acid (GABA) agonists and its major effects appear to be on the central nervous system. Piperazine was the anthelmintic with the greatest number of reports of toxicoses and suspecte...
T66552 N-Boc-piperazine
N-Boc-piperazine is a useful organic compound for research related to life sciences. The catalog number is T66552 and the CAS number is 57260-71-6.
T61592 Thalidomide-piperazine hydrochloride
Thalidomide-piperazine hydrochloride is a chemical compound with potential applications in the research of leprosy and multiple myeloma. It serves as a valuable tool in developmental biology, facilitating significant dis...
T66810 1-(Cyclopropylcarbonyl)piperazine
1-(Cyclopropylcarbonyl)piperazine is a useful organic compound for research related to life sciences. The catalog number is T66810 and the CAS number is 59878-57-8.
T66506 Boc-piperazine-benzoic acid
Boc-piperazine-benzoic acid is a useful organic compound for research related to life sciences. The catalog number is T66506 and the CAS number is 162046-66-4.
T83932 Phenyl-glutarimide 4'-piperazine
Phenyl-glutarimide 4'-piperazine, a piperazine-functionalized cereblon ligand, facilitates the development of PG-PROTACs with enhanced hydrolytic stability and potency compared to those produced with IMiD (immunomodulato...
T67044 1-(4-Methoxybenzyl)piperazine
1-(4-Methoxybenzyl)piperazine is a useful organic compound for research related to life sciences. The catalog number is T67044 and the CAS number is 21867-69-6.
T65657 N-(2-Hydroxyethyl)piperazine
N-(2-Hydroxyethyl)piperazine is a useful organic compound for research related to life sciences. The catalog number is T65657 and the CAS number is 103-76-4.
T65059 1-(2,4-Difluorophenyl)piperazine
1-(2,4-Difluorophenyl)piperazine is a useful organic compound for research related to life sciences. The catalog number is T65059 and the CAS number is 115761-79-0.
T66693 1-(2-Methoxyethyl)piperazine
1-(2-Methoxyethyl)piperazine is a useful organic compound for research related to life sciences. The catalog number is T66693 and the CAS number is 13484-40-7.
T64843 1,4-Bis(4-nitrophenethyl)piperazine
1,4-Bis(4-nitrophenethyl)piperazine is a useful organic compound for research related to life sciences and the catalog number is T64843.
T65071 1-(4-Bromophenyl)piperazine (hydrochloride)
1-(4-Bromophenyl)piperazine (hydrochloride) is a useful organic compound for research related to life sciences. The catalog number is T65071 and the CAS number is 68104-62-1.
T65963 1-(2-Chlorophenyl)piperazine hydrochloride
1-(2-Chlorophenyl)piperazine hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65963 and the CAS number is 41202-32-8.
T64560 1,4-Bis(4-nitrophenyl)piperazine
1,4-Bis(4-nitrophenyl)piperazine is a useful organic compound for research related to life sciences. The catalog number is T64560 and the CAS number is 16264-05-4.

Compounds

Navitoclax-piperazine
T12186
Synonym: ABT-263-piperazine
Target: BCL, Ligands for Target Protein for PROTAC
Sultosilic acid, piperazine salt
T28882
Synonym: A-585,Mimedran,piperazine-sultosylate,A585,A 585
Target:
1-(1-Naphthyl) piperazine hydrochloride
T21569
Synonym: 1-naphthalen-1-ylpiperazine hydrochloride,1-(Naphthalen-1-yl)piperazine hydrochloride
Target: Others
1-[(5-methylisoxazol-3-yl)methyl]piperazine
T8582
Synonym: Piperazine, 1-[(5-methyl-3-isoxazolyl)methyl]- (9CI)
Target: P2Y Receptor
Piperazine adipate
T7146
Synonym:
Target: Parasite
Piperazine Erastin
T16540
Synonym:
Target: Ferroptosis
Piperazine citrate
T16539
Synonym:
Target: GABA Receptor
1-(3-chloropyridin-2-yl)piperazine 2HCl
T50018
Synonym:
Target: Others
1-(2-Pyridyl)piperazine
T5105
Synonym: NSC13778
Target: Adrenergic Receptor
1-(3-Chlorophenyl)piperazine hydrochloride
T0615
Synonym: M-CPP hydrochloride
Target: Others
GNF-8625 monopyridin-N-piperazine hydrochloride
T40034
Synonym:
Target: Trk receptor
N-[2-nitro-4-(trifluoromethyl)phenyl]piperazine
T60231
Synonym:
Target: Others
1-{1H-pyrrolo[2,3-d]pyrimidin-4-yl}piperazine 2HCl
T50034
Synonym:
Target: Others
1-(4-fluorophenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]Piperazine
T9876
Synonym:
Target: Others
BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride
T40111L
Synonym:
Target: PD-1/PD-L1
Thalidomide-Piperazine-PEG3-NH2
T39895
Synonym: Thalidomide-Piperazine-PEG3-NH2
Target:
Thalidomide-Piperazine-PEG2-NH2
T39893
Synonym: Thalidomide-Piperazine-PEG2-NH2
Target:
1-(1-phenyltetrazol-5-yl)piperazine HCl
T50020
Synonym: 1-(1-phenyl-1H-1,2,3,4-tetrazol-5-yl)piperazine hydrochloride
Target: Others
BMY-14802
T67739
Synonym: alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol
Target: Sigma receptor
Thalidomide-Piperazine-Piperidine
T39711
Synonym:
Target:
PIPES
T40645
Synonym: 1,4-Piperazinediethanesulfonic acid,1,4-piperazine bis(ethanesulfonic acid),1,4-Piperazinebis(ethanesulfonic acid),PIPES
Target: Others
Thalidomide-piperazine-Boc
T39697
Synonym:
Target:
Piperazine sebacate
T34069
Synonym: Nematorazine
Target:
Acefylline piperazine
T70097
Synonym:
Target:
Thalidomide-Piperazine 5-fluoride
T39696
Synonym:
Target:
Thalidomide-Piperazine-Piperidine hydrochloride
T40231
Synonym:
Target:
4-hydroxy-3-Methoxyphenylglycol (piperazine salt)
T37373
Synonym:
Target:
ML267
T64340
Synonym: 4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide trifluoroacetate
Target: Others
NCT-502
T16277
Synonym: N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide
Target: Dehydrogenase
Triclofenol piperazine
T34935
Synonym: CI 416,Triclofenol piperazina,CI-416,CI416,Triclofenol piperazate
Target:
BMS-1166-N-piperidine-CO-N-piperazine
T40111
Synonym:
Target:
Benzyl-piperazine-CO-benzothiazole-4-methylpiperidine
T62461
Synonym:
Target: Others
Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine
T77598
Synonym: (4-(4-methoxyphenyl)piperazin-1-yl)(2-(4-methylpiperidin-1-yl)benzo[d]thiazol-6-yl)methanone
Target: Others
1-(2,3-Dichlorphenyl)-piperazine
T20999
Synonym: DCPP
Target: Others
Ipexidine mesylate
T32187
Synonym: Guanidino propyl piperazine,UNII-CI8CT0864P
Target:
11β-HSD1 inibitor 17
T67903
Synonym:
Target: Dehydrogenase
Piperazine 2HCl
T65396
Synonym:
Target:
N-Boc-piperazine
T66552
Synonym:
Target:
Thalidomide-piperazine hydrochloride
T61592
Synonym:
Target:
1-(Cyclopropylcarbonyl)piperazine
T66810
Synonym:
Target:
Boc-piperazine-benzoic acid
T66506
Synonym:
Target:
Phenyl-glutarimide 4'-piperazine
T83932
Synonym:
Target:
1-(4-Methoxybenzyl)piperazine
T67044
Synonym:
Target:
N-(2-Hydroxyethyl)piperazine
T65657
Synonym:
Target:
1-(2,4-Difluorophenyl)piperazine
T65059
Synonym:
Target:
1-(2-Methoxyethyl)piperazine
T66693
Synonym:
Target:
1,4-Bis(4-nitrophenethyl)piperazine
T64843
Synonym:
Target:
1-(4-Bromophenyl)piperazine (hydrochloride)
T65071
Synonym:
Target:
1-(2-Chlorophenyl)piperazine hydrochloride
T65963
Synonym:
Target:
1,4-Bis(4-nitrophenyl)piperazine
T64560
Synonym:
Target:
1 2 3
カタログ番号 製品名 別名 ターゲット
T0345 Estropipate Piperazine estrone sulfate,Pipestrone,Estrone sulfate piperazine salt Estrogen Receptor/ERR , Estrogen/progestogen Receptor
Estropipate (Piperazine estrone sulfate) is a natural estrogenic substance composed of estrone sulfate and piperazine.
TN3107 5-Deoxystrigol Others
5-Deoxystrigol is a highly active Striga germination stimulant. It has a protective effect on D-galactosamine (D-GalN) induced mice acute liver injury and has a protective effect on CCl4 induced mice acute liver injury.

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPH-03181 LaaA Protein, Pseudomonas azotoformans, Recombinant (His & Myc & SUMO) Pseudomonas azotoformans E. coli
Hydrolyzes L-prolinamide, L-proline-p-nitroanilide, L-alaninamide, L-methioninamide, piperidine-2-carboxamide and piperazine-2-carboxamide. Has a much lower activity towards piperazine-2-tert-butylcarboxamide. Does not h...