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Search Results for " recurrent "

ターゲット

21

阻害剤

3

天然化合物

15

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T26889 Borofalan(10B) L-4-Boronophenylalanine Others
Borofalan(10B) (L-4-Boronophenylalanine) echibits antineoplastic effects. Borofalan can be used in studies on recurrent or locally advanced head and neck cancer.
T7697 BIX-01294 Histone Methyltransferase , Autophagy
BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).
T1163 Betamethasone valerate Betnovate,Betaderm,Betamethasone 17-valerate,Luxiq Glucocorticoid Receptor
Betamethasone valerate (Luxiq) is a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions.
T1959 BIX-01294 trihydrochloride BIX 01294 Histone Methyltransferase , Autophagy
BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase.In a cell-free assay, the IC50=2.7 μM for G9a histone methyltransferase.
T77416 Opicinumab BIIB033 Others
Opicinumab (BIIB033) is a novel monoclonal antibody against LINGO-1 that may be used to prevent and delay acute optic neuritis and recurrent multiple sclerosis.
T2073 GSK2636771 GSK 2636771,GSK-2636771 PI3K
GSK2636771, an effective, specific, orally bioavailable, PI3Kβ inhibitor, has been used in cancer, lymphoma, solid neoplasm, recurrent solid neoplasm, and advanced malignant neoplasm.
T35390 Magrolimab Hu5F9-G4,Magrolimab (anti-CD47) Others
Magrolimab (Hu5F9-G4) is a humanized anti-CD47 IgG4 monoclonal antibody that exhibits its antitumor activity by blocking CD47 and binds primarily to the N-terminal pyroglutamate of CD47, and can be used in combination wi...
T11449L Golotimod Gamma-D-glutamyl-L-tryptophan,SCV 07 Antibiotic
Golotimod (SCV 07) is an antimicrobial dipeptide with immunomodulatory activity that significantly improves the efficacy of anti-tuberculosis therapy, induces thymic and splenic cell proliferation, modulates macrophage f...
T28778 Silperisone HCl RGH5002,SILA336,RGH-5002,Silperisone hydrochloride,SILA-336
Silperisone HCl (RGH-5002) blocks sodium and calcium channels in cells, decreases excitability and contractility of muscle cells, reduces peripheral tone, and acts as a muscle relaxant and peripheral vasodilator. Silperi...
T16152 Betamethasone 17-benzoate Kinesin
Betamethasone 17-benzoate is a representative steroid. It also can be used in the treatment of recurrent aphothous ulcers (RAU).
T17930 EC1167 Others
EC1169 is a targeted tubulysin conjugate that utilizes EC1167 as its linker. This compound shows promise in the treatment of recurrent metastatic, castration-resistant prostate cancer (MCRPC)[1].
T16071 MGB-BP-3 DNA/RNA Synthesis , Antibiotic
MGB-BP-3 is a synthetic antibiotic with bactericidal activity that inhibits bacterial DNA replication and can be used to study recurrent C. difficile infections.
T76789 Imalumab
Imalumab (BAX69), a recombinant human IgG1 monoclonal antibody, specifically targets macrophage inhibitory factor (MIF). It is utilized in the research of ovarian carcinoma, recurrent malignant ascites, and cancer [1].
T76918 Barecetamab
Barecetamab (ISU-104), a fully human anti-ErbB3 monoclonal antibody, is utilized in researching recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) [1].
T76970 Tagitanlimab
Tagitanlimab (HBM-9167), a humanized anti-PD-L1 antibody (IgG1κ type), selectively inhibits the PD-L1 and PD-1 interaction. It shows promise for investigation in recurrent or metastatic nasopharyngeal carcinoma (NPC) [1]...
T77108 Olinvacimab
Olinvacimab (TTAC-0001), a fully human anti-VEGFR2 monoclonal antibody, demonstrates antiangiogenic activity by inhibiting VEGF binding to KDR, with a dissociation constant (K d) of 0.23 nM. It is utilized in research fo...
T77815 EC1167 hydrochloride
EC1167 hydrochloride serves as the linker for EC1169, a prostate-specific membrane antigen-targeting tubulysin conjugate. EC1169 hydrochloride demonstrates potential in treating recurrent metastatic, castration-resistant...
T76997 Socazolimab
Socazolimab (ZKAB001), an anti-PD-L1 monoclonal antibody, demonstrates enduring safety and efficacy in treating recurrent or metastatic cervical cancer. Additionally, it shows promise for treating small cell lung cancer,...
T76920 Bectumomab
Bectumomab (IMMU-LL 2), a humanized IgG2a monoclonal antibody (mAb) against human CD22 (antigen), serves as an anti-lymphoma agent. It is utilized in imaging procedures when combined with technetium 99 (Tc99m LL2 Fab), a...
T11449L2 Golotimod (TFA) (229305-39-9 free base) SCV 07 (TFA),Gamma-D-glutamyl-L-tryptophan (TFA),Golotimod (TFA) STAT
Golotimod TFA (SCV 07 TFA) is an immunomodulatory peptide with antibacterial properties that significantly increases the effectiveness of anti-tuberculosis studies, stimulates thymus and splenocyte proliferation and impr...
T11449 Golotimod hydrochloride (229305-39-9 free base) Golotimod hydrochloride,Gamma-D-glutamyl-L-tryptophan hydrochloride,SCV 07 hydrochloride STAT
Golotimod hydrochloride (SCV 07 hydrochloride) is an immunomodulating peptide with antimicrobial properties. It enhances antituberculosis therapy effectiveness, promotes thymic and splenic cell proliferation, and boosts ...
カタログ番号 製品名 別名 ターゲット
T5231 2-Methylsuccinic acid Pyrotartaric Acid,Methylbutanedioic acid Others , Endogenous Metabolite
2-Methylsuccinic acid (Pyrotartaric Acid) is a normal metabolite found in human fluids. Increased urinary levels of 2-Methylsuccinic acid (Pyrotartaric Acid) (together with ethylmalonic acid) are the main biochemical mea...
T0884 1-Docosanol Behenic alcohol,Behenyl alcohol,n-Docosanol,Docosanol Antifection , HSV
1-Docosanol (Behenic alcohol) is a saturated 22-carbon aliphatic alcohol with antiviral activity. 1-Docosanol has a distinct mechanism of action and inhibits fusion between the plasma membrane and the herpes simplex viru...
T4716 Pyrrole-2-carboxylic acid 2-Pyrrolecarboxylic acid,Minaline Endogenous Metabolite
Pyrrole-2-carboxylic acid (Minaline) was first identified as a degradation product of sialic acids, then as a derivative of the oxidation of the D-hydroxyproline isomers by mammalian D-amino acid oxidase. The latter rela...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-04779 BTN3A2 Protein, Human, Recombinant (His) Human HEK293 Cells
The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A2 is overexpressed in gastric tu...
TMPY-04483 IRAK4 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4...
TMPY-01061 FGF-10 Protein, Human, Recombinant Human E. coli
Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes...
TMPY-04311 RAB11B Protein, Human, Recombinant (His) Human HEK293 Cells
The two recurrent dominant mutations in RAB11B leading to a neurodevelopmental syndrome, likely caused by altered GDP/GTP binding that inactivate the protein and induce GEF binding and protein mislocalization.
TMPY-00025 Mammaglobin B/SCGB2A1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
SCGB2A1 represented a novel, prognostic factor for CRC, and that expression of SCGB2A1 correlated with chemoresistance, radioresistance and cancer cell stemness. SCGB2A1 is a top differentially expressed gene in all majo...
TMPJ-00517 WIF-1 Protein, Human, Recombinant (His) Human HEK293 Cells
Wnt Inhibitory Factor 1 (WIF1) is a secreted protein, which binds WNT proteins and inhibits their activities. WNT proteins are extracellular signaling molecules involved in the control of embryonic development. WIF1 cont...
TMPJ-00588 CEACAM7 Protein, Human, Recombinant (His) Human HEK293 Cells
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 (CEACAM7) is a member of the immunoglobulin superfamily A and CEA family. CEACAM7 localizes to the cell membrane and contains one Ig-like C2-type domain and one I...
TMPY-06802 HSV 2 (strain 333) Glycoprotein D/gD Protein (His) HSV2 HEK293 Cells
Herpes simplex viruses (human herpesviruses types 1 and 2) commonly cause recurrent infection affecting the skin, mouth, lips, eyes, and genitals. Herpes simplex virus type 2 (HSV-2) infection is responsible for signific...
TMPJ-00361 Endoglin Protein, Human, Recombinant (Trx & His) Human E. coli
Endoglin is a single-pass type I membrane protein which restricted to endothelial cells in all tissues except bone marrow. Endoglin as major glycoprotein of vascular endothelium, it has been found on endothelial cells, a...
TMPY-04476 MVK Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
Mevalonate kinase belongs to the GHMP kinase family, Mevalonate kinase subfamily. It can be found in a wide variety of organisms from bacteria to mammals. Mevalonate kinase may be a regulatory site in the cholesterol bio...
TMPY-05028 NOTCH2NL Protein, Human, Recombinant (mFc) Human HEK293 Cells
NOTCH2NLA (Notch 2 N-Terminal Like A) is a Protein Coding gene. NOTCH2NL, human-specific paralogs of the NOTCH2 receptor, stood out for their ability to promote cortical progenitor maintenance. It belongs to the NOTCH fa...
TMPY-02849 WIF1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
WIF1, also known as WIF-1 and wnt inhibitory factor 1, is a secreted protein that binds WNT proteins and inhibits their activities. It contains a WNT inhibitory factor (WIF) domain and 5 epidermal growth factor (EGF)-lik...
TMPY-01854 DPP10 Protein, Human, Recombinant (His) Human HEK293 Cells
Inactive dipeptidyl peptidase 1, also known as Dipeptidyl peptidase IV-related protein 3, Dipeptidyl peptidase X, Dipeptidyl peptidase-like protein 2, DPRP-3, DPL2 and DPP1, is a single-pass type II membrane protein w...
TMPJ-00329 CD19 Protein, Rhesus macaque, Recombinant (hFc) Rhesus HEK293 Cells
CD19 is a single-pass type I membrane protein containing 2 Ig-like C2-type (immunoglobulin-like) domains. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recog...
TMPY-01605 STIM1 Protein, Human, Recombinant (His) Human HEK293 Cells
Stromal interaction molecule 1, also known as STIM1 and GOK, is a cell membrane, a single-pass type I membrane protein and a endoplasmic reticulum membrane protein. STIM1 / GOK is ubiquitously expressed in various human ...
BTN3A2 Protein, Human, Recombinant (His)
TMPY-04779
Species: Human
Expression System: HEK293 Cells
IRAK4 Protein, Human, Recombinant (His)
TMPY-04483
Species: Human
Expression System: Baculovirus Insect Cells
FGF-10 Protein, Human, Recombinant
TMPY-01061
Species: Human
Expression System: E. coli
RAB11B Protein, Human, Recombinant (His)
TMPY-04311
Species: Human
Expression System: HEK293 Cells
Mammaglobin B/SCGB2A1 Protein, Human, Recombinant (hFc)
TMPY-00025
Species: Human
Expression System: HEK293 Cells
WIF-1 Protein, Human, Recombinant (His)
TMPJ-00517
Species: Human
Expression System: HEK293 Cells
CEACAM7 Protein, Human, Recombinant (His)
TMPJ-00588
Species: Human
Expression System: HEK293 Cells
HSV 2 (strain 333) Glycoprotein D/gD Protein (His)
TMPY-06802
Species: HSV2
Expression System: HEK293 Cells
Endoglin Protein, Human, Recombinant (Trx & His)
TMPJ-00361
Species: Human
Expression System: E. coli
MVK Protein, Human, Recombinant (His & GST)
TMPY-04476
Species: Human
Expression System: Baculovirus Insect Cells
NOTCH2NL Protein, Human, Recombinant (mFc)
TMPY-05028
Species: Human
Expression System: HEK293 Cells
WIF1 Protein, Mouse, Recombinant (His)
TMPY-02849
Species: Mouse
Expression System: HEK293 Cells
DPP10 Protein, Human, Recombinant (His)
TMPY-01854
Species: Human
Expression System: HEK293 Cells
CD19 Protein, Rhesus macaque, Recombinant (hFc)
TMPJ-00329
Species: Rhesus
Expression System: HEK293 Cells
STIM1 Protein, Human, Recombinant (His)
TMPY-01605
Species: Human
Expression System: HEK293 Cells