Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a fatty acid amide hydrolase inhibitor with anti-tumor effect. It binds to the plasma membrane and alters lipid organization.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 31,000 | |||
5 mg | 在庫あり | ¥ 67,500 | |||
10 mg | 在庫あり | ¥ 107,500 | |||
25 mg | 在庫あり | ¥ 170,500 | |||
50 mg | 在庫あり | ¥ 229,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 66,000 |
説明 | (Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a fatty acid amide hydrolase inhibitor with anti-tumor effect. It binds to the plasma membrane and alters lipid organization. |
ターゲット&IC50 | Jurkat cells:40 μM |
In vitro | Minerval (25-50 μM; 72 hours) causes a marked and concentration-dependent increase in the proteolytic cleavage of PARP, a molecular marker of apoptosis. Minerval (25-75 μM; 72 hours) impairs Jurkat cell growth in a time- and concentration-dependent manner (IC50: 40 μM)[1]. |
In vivo | In nude mice infected with Jurkat cells, Minerval significantly inhibits tumour growth[1]. |
別名 | 2-Hydroxyoleic acid, 2-OHOA, Minerval |
分子量 | 298.46 |
分子式 | C18H34O3 |
CAS No. | 56472-29-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (167.52 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
(Rac)-Idroxioleic acid 56472-29-8 Apoptosis membrane 2-Hydroxyoleic acid inhibit plasma 2-OHOA Inhibitor Idroxioleic acid oleic acid Minerval (Rac)Idroxioleic acid (Rac) Idroxioleic acid inhibitor