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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T40312 | Plasma kallikrein-IN-1 | ||
Plasma kallikrein-IN-1 is a PKK inhibitor with an IC 50 value of 0.5 nM. | |||
T61403 | Plasma kallikrein-IN-3 | ||
Plasma kallikrein-IN-3, a potent inhibitor ( IC 50 : 0.15 μM) of plasma kallikrein, finds application in research related to hereditary angioedema, diabetic macular edema, and diabetic retinopathy [1]. | |||
T72337 | Plasma kallikrein-IN-2 | ||
Plasma kallikrein-IN-2, a potent inhibitor of plasma kallikrein (PKal) with an inhibitory concentration (IC) 50 value of 0.1 nM, is utilized in research targeting hereditary angioedema, diabetic macular edema, and diabet... | |||
T16369 | O-Desmethyl gefitinib | EGFR | |
O-Desmethyl gefitinib inhibits EGFR (IC50: 36 nM in subcellular assays). In human plasma, O-Desmethyl gefitinib is an active metabolite of Gefitinib. The formation of O-desmethyl gefitinib is dependent on the CYP2D6 acti... | |||
T9215 | ELOVL6-IN-2 | Others | |
ELOVL6-IN-2 is a orally active and selective ELOVL6 inhibitor. | |||
T26019 | R59949 | R-59949,R 59949 | Others , PKC |
R59949 is used as a Diacylglycerol kinase (DGK) inhibitor. | |||
T14984 | CLP257 | Potassium Channel | |
CLP257 is a selective K+-Cl− cotransporter KCC2 activator (EC50: 616 nM) and it is inactive against NKCC1, GABAA receptors, KCC1, KCC3 or KCC4. CLP257 alleviates hypersensitivity in rats with neuropathic painc and it al... | |||
T11793 | KY-05009 | Wnt/beta-catenin | |
KY-05009 is a chemical compound that effectively suppresses TGF-β1-induced epithelial-to-mesenchymal transition (EMT) in human lung adenocarcinoma cells, reduces TNIK protein expression and the transcriptional activity o... | |||
T34532 | Sari 59-801 | Sari-59-801 | Others |
Sari 59-801 is a novel, orally effective hypoglycemic compound. | |||
T1736 | Apixaban | BMS-562247-01 | Factor Xa |
Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the conversion of prothrombin to thrombin and pr... | |||
T8235 | L-732138 | Neurokinin receptor | |
L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM) | |||
TP1158 | Copper tripeptide | GHK-Cu | Others , Endogenous Metabolite |
Copper tripeptide (GHK-Cu) is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine. The tripeptide has strong affinity for copper(II) and was first isolated from human plasma. It can be found... | |||
T12146 | N-Desmethyl-Apalutamide | N-Desmethyl Apalutamide | P450 , Androgen Receptor |
N-Desmethyl-Apalutamide is a less potent antagonist of the androgen receptor, is an active Apalutamide metabolite. | |||
T2499 | Torcetrapib | CP-529414 | CETP |
Torcetrapib (CP-529414) is a cholesteryl ester transfer protein (CETP) inhibitor that reduces the heterotypic transfer of cholesteryl ester from HDL to LDL and/or VLDL. Torcetrapib failed in phase III trials due to exces... | |||
T10353 | APX-115 free base | Ewha-18278 free base | NADPH-oxidase , NADPH |
APX-115 free base (Ewha-18278 free base) (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX-115 effectively prevents kid... | |||
T12372 | PAT-505 | EGFR | |
PAT-505 is an orally available, selective and potent inhibitor of autologous epidermal growth factor (IC50 2 nM in Hep3B cells, 9.7 nM in human blood, 62 nM in mouse plasma). | |||
TP2124L | Somatostatin 1-28 acetate | Somatostatin 1-28 acetate(74315-46-1 Free base) | Somatostatin |
Somatostatin 1-28 acetate circulates in human plasma. Approximately 46% of the total somatostatin-like immunoreactivity in plasma is due to Somatostatin 1-28 acetate. | |||
T6999 | Teneligliptin hydrobromide | Teneligliptin hydrobromide anhydrous,MP-513 (hydrobromide) | Others , Proteasome , DPP-4 |
Teneligliptin hydrobromide (MP-513 (hydrobromide)) is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor; competitively inhibited human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50 ... | |||
T22714 | Decynium 22 | Others | |
Decynium 22 is a plasma membrane monoamine transporter (PMAT) inhibitor | |||
T19861 | Niceritrol | Perycit,Cardiolipol,Bufor | Others |
Niceritrol (Cardiolipol) is a niacin ester that reduces cholesterol and triglycerides in total plasma and in the VLD and LD lipoprotein fractions. | |||
T6048 | Dalcetrapib | JTT-705,RO4607381 | CETP |
Dalcetrapib (RO4607381), a rhCETP inhibitor (IC50=0.2 μM), increases the plasma HDL cholesterol. | |||
TP1062L | Katacalcin acetate(85916-47-8 free base) | PDN 21 acetate | Others |
Katacalcin acetate(85916-47-8 free base) (PDN 21 acetate) is a potent plasma calcium-lowering peptide. | |||
T39350 | Sebetralstat | KVD900 | Others |
Sebetralstat (KVD900) is an inhibitor of plasma kallikrein and can be used in studies about metabolic diseases. | |||
T20802 | Flumethasone pivalate | Locacorten,NSC-107680,Lorinden,NSC 107680,NSC107680,Locorten | Others |
Flumethasone pivalate (Locorten) has antipruritic, anti-inflammatory, and vasoconstrictive properties and can be used in studies about adrenocortical suppression, cutaneous atrophy, plasma transcortin binding, and telang... | |||
T11885 | LSP-249 | Others | |
LSP-249 is a plasma kallikrein inhibitor under the study for angioedema, with an EC50 less than 100 nM in cell. | |||
T5039 | Aminohippurate sodium | Sodium 4-aminohippurate Hydrate,Sodium p-aminohippurate,p-Aminohippuric acid sodium salt | Others |
Aminohippurate sodium (Sodium p-aminohippurate) is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. | |||
T28232 | Oleoylestrone | Estrone 3-oleate,MP 101,MP-101,MP101 | Antioxidant |
Oleoylestrone (MP-101) is present in plasma and adipose tissue, has potential antioxidant effects, induces loss of body fat in rats, and can be used for weight loss. | |||
T2655 | CEP-37440 | CEP37440 | FAK , ALK |
CEP-37440 is an effective and specific Dual FAK/ALK inhibitor with IC50s of 120 nM(ALK cellular in 75% human plasma) and 2.3 nM (FAK). | |||
T3956 | Sodium ionophore III | ETH2120 | Sodium Channel |
Sodium ionophore III (ETH2120) is a Na+ ionophore suitable for the test of sodium activity in plasma, serum, and blood. | |||
T34705 | SR4554 | SR 4554 | |
SR4554 is a fluorine-containing 2-nitroimidazole, designed as a hypoxia marker detectable with 19F magnetic resonance spectroscopy (MRS). SR-4554 has plasma pharmacokinetic and toxicity profiles suitable for use as a hyp... | |||
T1148 | Menbutone | Naftobil,Genabilic acid,Genabilin | Others |
Menbutone (Genabilin) is a derivative of oxobutyric acid, and is a choleretic. Menbutone shows a rapid onset of action, reaching its maximum plasma level within 1 hour and lasting for roughly 10 hours. | |||
T10415 | Autotaxin-IN-3 | PDE | |
Autotaxin-IN-3 is an inhibitor of Autotaxin (IC50 = 2.4 nM) which is responsible for the increase in lysophosphatidic acid in ascites and plasma. | |||
T29842 | Alclofenac | W 7320,MY 101,BRN 2116510,W-7320,W7320 | Others |
Alclofenac (W-7320) has a significant effect on the acute phase protein response and the degree of L-tryptophan binding to plasma protein and can be used in the treatment of patients with chronic rheumatism. | |||
T14358 | Avoralstat | BCX4161 | Others |
Avoralstat (BCX4161) is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema. | |||
T31101 | CRT0273750 | CRT 0273750,CRT-0273750 | PDE |
CRT0273750 regulates plasma LPA levels and is suitable for in vivo studies. CRT0273750 is an autotaxin (ATX) inhibitor with IC50 of 0.014 μM. | |||
T12015 | Methyl homoveratrate | Others | |
Methyl homoveratrate, a McN5691 (RWJ-26240) metabolite detected in vivo in plasma, urine, and fecal extracts, functions as a voltage-sensitive calcium channel blocker. | |||
TP1116L | Kinetensin acetate(103131-69-7 free base) | Kinetensin (human) acetate | Neurotensin Receptor |
Kinetensin acetate(103131-69-7 free base) is isolated from pepsin-treated human plasma. Kinetensin acetate(103131-69-7 free base) is a neurotensin-like peptide. | |||
T9106 | E1231 | Sirtuin | |
E1231 is an activator of SIRT1 . E1231 protects from experimental atherosclerosis and lowers plasma cholesterol and triglycerides by enhancing ABCA1 expression. | |||
T36926L | Neuropeptide SF (human) aceate | Others | |
Neuropeptide SF (human) aceate is a neuropeptide that augmented paraventricular CRH release and increased ACTH and corticosterone levels in the plasma. | |||
T38759 | ONO-8430506 | PDE | |
ONO-8430506 is an orally available, potent autotaxin (ATX)/ENPP2 inhibitor (IC90: 100 nM) that inhibits ATX activity in mouse plasma. | |||
T17232 | Vidupiprant | AMG 853 | Prostaglandin Receptor |
Vidupiprant (AMG 853) is an effective dual antagonist of CRTH2 and prostanoid D receptor with IC50s of 8 nM and 35 nM in human plasma. Vidupiprant can be used in studies about the treatment of asthma. | |||
T26955 | Cavosonstat | N91115,N 91115,N-91115 | GSNOR , CFTR |
Cavosonstat (N91115) is an orally active S-nitrosoglutathione reductase (GSNOR) inhibitor that promotes cystic fibrosis transmembrane conductance regulator (CFTR) maturation and plasma membrane stabilization.Cavosonstat ... | |||
T1423 | 3-Methylsalicylic acid | Hydroxytoluic acid,o-Cresotic acid | COX |
3-Methylsalicylic acid (o-Cresotic acid) is a long-acting salicylate derivative with antilipidemic properties. Hydroxytoluic acid has been shown to lower plasma free fatty acid and cholesterol levels. | |||
T38400 | Triclabendazole sulfoxide | TCBZ-SO | BCRP , Parasite |
Triclabendazole sulfoxide (TCBZ-SO) is a main plasma metabolite of Triclabendazole. Triclabendazole sulfoxide inhibits membrane transporter ABCG2/BCRP and exhibits anti-parasite effects. | |||
T23764 | AZ3976 | AZ 3976,AZ-3976 | PAI-1 |
AZ3976 is an inhibitor of PAI-1 with an IC50 of 16 μM in a plasma clot lysis assay. AZ3976 displays profibrinolytic activities. | |||
T12470 | Picloxydine | Antibacterial | |
Picloxydine is a heterocyclic biguanide with antiplaque and antibacterial activity. | |||
T9565 | OSBPL7-IN-1 | Others | |
OSBPL7-IN-1 is an orally active inhibitor of oxysterol binding protein like 7 (OSBPL7). OSBPL7-IN-1 promotes an increase of ABCA1 at the plasma membrane without affecting mRNA expression[1]. | |||
T40437L | Caloxin 2A1 acetate | Proton pump | |
Caloxin 2A1 acetate is an inhibitor of extracellular plasma membrane Ca2+-ATPase (PMCA) peptide. Caloxin 2A1 acetate inhibits Ca2+-dependent formation of the 140-kDa acid-stable acylphosphate. | |||
T1554 | Iohexol | Mitophagy , Autophagy | |
Iohexol is a contrast agent. The osmolality of iohexol ranges from 322 mOsm/kg-approximately 1.1 times that of blood plasma-to 844 mOsm/kg, almost three times that of blood. | |||
T8556 | Z-Gly-Gly-Arg-AMC TFA (66216-78-2 free base) | Z-Gly-Gly-Arg-AMC TFA | Others |
Z-Gly-Gly-Arg-AMC TFA (66216-78-2 free base) is a thrombin-specific fluorogenic substrate for testing thrombin generation in PRP and platelet-poor plasma (PPP). |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T16075 | (Rac)-Idroxioleic acid | 2-Hydroxyoleic acid,2-OHOA,Minerval | Apoptosis |
(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a fatty acid amide hydrolase inhibitor with anti-tumor effect. It binds to the plasma membrane and alters lipid organization. | |||
T60104 | Mycophenolic acid-β-D-glucuronide solution | Others | |
Mycophenolic acid glucuronide is the glucuronide metabolite of mycophenolic acid in human plasma. | |||
T5556 | 5a-Pregnane-3,20-dione | Endogenous Metabolite | |
5a-Pregnane-3,20-dione is a biologically active 5-alpha-reduced metabolite of plasma progesterone | |||
T5269 | N-Acetylornithine | Acetyl-ornithine,N-Acetyl-L-ornithine | Others , Endogenous Metabolite |
N-Acetylornithine (N-Acetyl-L-ornithine) is a minor component of deproteinized blood plasma of human blood. Human blood plasma contains a variable amount of acetylornithine, averaging 1.1 +/- 0.4 μmol/L. Urine contains a... | |||
T5219 | L-Alloisoleucine | L-allo-Isoleucine,(3R)-LS-Isoleucine,L(+)-Alloisoleucine | Others , Endogenous Metabolite |
L-Alloisoleucine (L-allo-Isoleucine) is a branched chain amino acid and is a stereoisomer of L-isoleucine. It is a common constituent of human plasma (albeit at low levels). L-alloisoleucine is produced as a byproduct of... | |||
T3367 | Macranthoidin B | Macranthoiside I | Others |
Macranthoidin B (Macranthoiside I), a saponin extracted from Flos Lonicerae is a main bioactive saponin in rat plasma (p.o.). | |||
T14840 | Butyrylcarnitine | Endogenous Metabolite | |
Butyrylcarnitine is a plasma metabolite that is an indicator of abnormal metabolism due to disease and is used in the diagnosis of heart failure and pancreatic cysts. | |||
T5303 | Isethionic acid sodium salt | Sodium isethionate | Others , Endogenous Metabolite |
Isethionic acid sodium salt (Sodium isethionate) is an organosulfur compound containing a short chain alkane sulfonate linked to a hydroxyl group. Mammals are able to endogenously synthesize Isethionic acid sodium salt v... | |||
T5573 | Coenzyme Q9 | Ubiquinone Q9,Ubiquinone 9,CoQ9 | Apoptosis , Endogenous Metabolite |
Coenzyme Q9 (Ubiquinone 9) (CoQ9) is a normal constituent of human plasma. CoQ9 in human plasma may originate as a product of incomplete CoQ10 biosynthesis or from the diet. | |||
T11012 | Dextran | Dextran 40 | Platelet aggregation |
Dextran has an inhibitory effect on platelet aggregation and coagulation factors, and is used as an agent for increasing plasma volume. | |||
T1556 | Ornidazole | Tiberal,Ornidazolum,NSC 95075,Ro 7-0207 | Antibacterial , Antibiotic , Parasite |
Ornidazole (Tiberal) is a nitroimidazole antiprotozoal agent used in ameba and trichomonas infections. It is partially plasma-bound and also has radiation-sensitizing action. | |||
TCS1772 | Dehydroabietic acid | Dehydroabietate | Antifection |
1. Dehydroabietic acid (Dehydroabietate) (DAA) is an EBV-EA activation inhibitor. 2. DAA is a useful food-derived compound for treating obesity-related diseases, by decreasing plasma glucose, insulin levels, plasma trigl... | |||
T19398 | L-Octanoylcarnitine | Endogenous Metabolite | |
L-Octanoylcarnitine is the active octanoylcarnitine present in plasma and is a potential biomarker for breast cancer. | |||
T5074 | Cholesteryl palmitate | Others , Endogenous Metabolite | |
Cholesteryl palmitic acid is a cholesteryl ester. A cholesteryl ester is an ester of cholesterol. Fatty acid esters of cholesterol constitute about two-thirds of the cholesterol in the plasma. Cholesterol is a sterol (a ... | |||
T4863 | DL-Homocysteine | 2-Amino-4-mercaptobutyric acid | Endogenous Metabolite |
DL-Homocysteine (2-Amino-4-mercaptobutyric acid) is a potential marker for tumor cell growth. increased plasma homocysteine is a risk factor for coronary heart disease and carcinogenesis. | |||
T4810 | Pyrocatechuic acid | 3-Hydroxysalicylic acid,O-Pyrocatechuic acid,Catecholcarboxylic acid,NSC 27435,2,3-Dihydroxybenzoic acid | Others , Endogenous Metabolite |
Pyrocatechuic acid (Catecholcarboxylic acid), a normal human benzoic acid metabolite found in plasma, has increased levels after aspirin ingestion. | |||
T5261 | (E)-Oct-2-enoic acid | trans-2-Octenoic acid,2-Octenoate,2-Octenoic acid | Others , Endogenous Metabolite |
(E)-Oct-2-enoic acid (2-Octenoate) is a normal organic acid produced by hepatic microsomal oxidation of aliphatic aldehydes and is a metabolite naturally found in the urine and plasma. | |||
TN3820 | Demethoxydeacetoxypseudolaric acid B | Others | |
Demethoxydeacetoxypseudolaric acid B's the metabolic reaction of TDA in vivo is mainly occurred in blood and contributes to be the hydrolysis of plasma esterase to ester bond, as well as the glucosylation reaction. | |||
TN6710 | Methyl acetylsalicylate | ACETYLSALICYLIC ACID METHYL ESTER | Others |
Methyl acetylsalicylate (ACETYLSALICYLIC ACID METHYL ESTER) is a natural product isolated from Pisum sativum. Inhibition of collagen-induced human platelet rich plasma aggregation | |||
TN6752 | Dimethyl sulfone | Endogenous Metabolite | |
Dimethyl sulfone exists in all living organisms, ranging from bacteria to humans. It derives from dietary sources, from intestinal bacterial metabolism and from human endogenous methanethiol metabolism. Dimethyl sulfone ... | |||
T1436 | 4-Aminohippuric Acid | p-Aminohippuric acid | Amino Acids and Derivatives , Endogenous Metabolite |
4-Aminohippuric Acid is the glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. | |||
T5590 | 2-(4-Methoxyphenyl)acetic acid | 4-Methoxyphenylacetic acid | Others , Endogenous Metabolite |
2-(4-Methoxyphenyl)acetic acid (4-Methoxyphenylacetic acid) is a plasma metabolite, found in normal human urine, cerebrospinal fluid, and brain tissue. | |||
T0570 | 3,5-Dihydroxybenzoic acid | Others , Endogenous Metabolite | |
3,5-Dihydroxybenzoic Acid is a metabolite of alkylresorcinol in human urine and plasma. It is also used as a biomarker of whole grain wheat and rye. | |||
T5295 | 1-Hydroxyoctadecane | 1-Octadecanol,Stearyl alcohol,Octadecanol | Others , Endogenous Metabolite |
1-Hydroxyoctadecane (OctadecanolOctadecanol) is a fatty alcohol present in human and is normally incorporated into plasmalogen lipids. Sjogren-Larsson syndrome is defined by the triad of ichthyosis, mental retardation, a... | |||
TN1305 | Ethoxysanguinarine | 6-Ethoxydihydrosanguinarine | Apoptosis , AChR |
Ethoxysanguinarine (6-Ethoxydihydrosanguinarine) shows human blood acetylcholinesterase (HuAChE) and human plasma butyrylcholinesterase (HuBuChE) inhibitory activity, with IC50 values of 0.83 +/- 0.04 microM and 4.20 +/-... | |||
T4940 | 3-Methylhistamine dihydrochloride | Others , Endogenous Metabolite | |
N tau-methylhistamine is one of the histamine metabolites. N tau-methylhistamine in plasma and urine is a good parameter for histamine release, and the determination of this histamine metabolite is generally less hampere... | |||
T5968 | DL-Homocysteine thiolactone hydrochloride | DL-Homocysteinethiolactone hydrochloride | Endogenous Metabolite |
DL-Homocysteine thiolactone hydrochloride (DL-Homocysteinethiolactone hydrochloride) is a cysteine derivative that binds to and induces conformational changes in various plasma proteins, slowing coagulation and inducing ... | |||
TN2023 | 8-Oxoepiberberine | Oxyepiberberine | Others |
8-Oxoepiberberine (Oxyepiberberine) is an alkaloid metabolite in the plasma after oral administration of Zuojin formula. Zuojin formula is a traditional chinese medicine used to treat gastrointestinal disease. | |||
T5239 | Cholesteryl sulfate sodium | Cholesterol 3-Sulfate Sodium Salt,Sodium Cholesteryl Sulfate | Endogenous Metabolite , PKC |
Cholesteryl sulfate sodium (Sodium Cholesteryl Sulfate) is a sterol sulfate in human plasma. Cholesteryl sulfate sodium is a component of cell membrane and has a regulatory function. Cholesteryl sulfate sodium also activ... | |||
T4819 | Pipecolic acid | (±)-Piperidine-2-carboxylic acid,2-Piperidinecarboxylic acid,Pipecolinic acid,Homoproline | Others , Endogenous Metabolite , Antibacterial |
Pipecolic acid (2-Piperidinecarboxylic acid), a metabolite of lysine found in human physiological fluids such as urine, plasma and CSF, is an important regulator of immunity in plants and humans alike. | |||
T0131 | Cepharanthine | NSC-623442 | Apoptosis , TNF , HIV Protease , Autophagy |
Cepharanthine (NSC-623442), a biscoclaurine alkaloid, suppresses tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and inhibits cytokine production. | |||
T13516 | 5-Methyltetrahydrofolic acid | 5-Methyl THF | Endogenous Metabolite |
5-Methyltetrahydrofolic acid (5-Methyl THF) is a biologically active form of folic acid and a methylated derivate of tetrahydrofolate. It is the predominant natural dietary folate and the principal form of folate in plas... | |||
T5076 | L-Allothreonine | L-allo-Threonine | Others , Endogenous Metabolite |
L-Allothreonine (L-allo-Threonine) is an essential amino acid in humans. L-Allothreonine is abundant in human plasma, particularly in newborns. Severe deficiency of threonine causes neurological dysfunction and lameness ... | |||
T4814 | (R)-5-Oxopyrrolidine-2-carboxylic acid | D-Pyroglutamic acid,(R)-(+)-2-Pyrrolidone-5-carboxylic acid | Others , Endogenous Metabolite |
(R)-5-Oxopyrrolidine-2-carboxylic acid (D-Pyroglutamic acid) is a cyclic derivative of glutamic acid, physiologically present in mammalian tissues. It has been shown that PCA releases GABA from the cerebral cortex and di... | |||
T2P2919 | (2S,3R,4S)-4-Hydroxyisoleucine | (4S)-4-Hydroxy-L-isoleucine,Hydroxyisoleucine | PI3K |
(2S,3R,4S)-4-Hydroxyisoleucine (Hydroxyisoleucine) from fenugreek (Trigonella foenum-graecum) seeds is a potential insulinotropic (anti-diabetic) and anti-obesity amino acid. HIL stimulates glucose-dependent insulin secr... | |||
TWO2727 | Propane-1,2,3-triyl tripalmitate | Palmitic Triglyceride,Tripalmitin,Tripalmitoylglycerol,Glycerol Tripalmitate | Others , Endogenous Metabolite |
Propane-1,2,3-triyl tripalmitate (Glycerol Tripalmitate) is a triacylglycerol found in dietary fats. Tripalmitin increases body weight and plasma LDL levels and reduces hepatic LDL receptor mRNA levels in hamsters fed a ... | |||
T5214 | Cholesteryl linoleate | CE(18:2(9Z,12Z)),Cholesterol Linoleate,Linoleic Acid cholesteryl ester | Others , Endogenous Metabolite |
Cholesteryl linoleate (Linoleic Acid cholesteryl ester) is a cholesterol ester found in LDL. Cholesteryl linoleate is transferred to the plasma membrane of macrophages and CHO cells expressing 15-lipoxygenase (15-LO) via... | |||
T14001 | 11-Beta-hydroxyandrostenedione | NSC-17102,4-Androsten-11β-ol-3,17-dione | Endogenous Metabolite |
11-Beta-hydroxyandrostenedione (NSC-17102) is a steroid mainly found in the adrenal origin (11β-hydroxylase is present in adrenal tissue, but absent in ovarian tissue), which is a 11β-hydroxysteroid dehydrogenase isozyme... | |||
T10619 | Bromelain | Apoptosis , Others | |
Bromelain is an anti-inflammatory drug derived from pineapple stem. It acts through down-regulation of plasma kininogen, degradation of advanced glycation end-product receptors, inhibition of Prostaglandin E2 expression,... | |||
T5004 | Hyaluronic acid sodium | Sodium Hyaluronate | Others |
Hyaluronic acid sodium (Sodium Hyaluronate) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is unique among glycosaminoglycans in that it is nonsu... | |||
T0884 | 1-Docosanol | Behenic alcohol,Behenyl alcohol,n-Docosanol,Docosanol | Antifection , HSV |
1-Docosanol (Behenic alcohol) is a saturated 22-carbon aliphatic alcohol with antiviral activity. 1-Docosanol has a distinct mechanism of action and inhibits fusion between the plasma membrane and the herpes simplex viru... | |||
T5280 | 3-Chloro-L-Tyrosine | 3-Chlorotyrosine,Chlorotyrosine | Others , Endogenous Metabolite |
3-Chloro-L-Tyrosine (Chlorotyrosine), a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low-density lipoprotein isolated from human atherosclerotic intima. In particular, myeloperoxidase h... | |||
T5302 | (R)-pyrrolidine-2-carboxylic acid | D-Proline | Others , Endogenous Metabolite |
(R)-pyrrolidine-2-carboxylic acid (D-Proline) is an isomer of the naturally occurring amino acid, L-Proline. D-amino acids have been found in relatively high abundance in human plasma and saliva. These amino acids may be... | |||
T7031 | Aristolochic acid B | Aristolochic Acid II | DNA |
Aristolochic acid B (Aristolochic Acid II) is one of the major components of the carcinogenic plant extract aristolochic acid, is known to be mutagenic and to form DNA adducts in vitro and in vivo, Aristolochic acid B sh... | |||
T36831 | 9-Oxononanoic Acid | 9-ONA | Phospholipase , CPT |
9-Oxononanoic Acid is an oxidized fatty acid, formed by the autoxidation of linoleic acid, which enhances phospholipase A2 (PLA2) activity and increases the production of thromboxane B2 in isolated human plasma.9-Oxonona... | |||
TN1853 | Lariciresinol | VEGFR , Antifection | |
Lariciresinol is an enterolignan precursor, it possesses fungicidal activities by disrupting the fungal plasma membrane and therapeutic potential as a novel antifungal agent for the treatment of fungal infectious disease... | |||
T4S21320 | ISOGINKGETIN | 4',4'''-Dimethylamentoflavone | MMP , Others |
1. ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of adiponecti... | |||
T4877 | L-Homocystine | Endogenous Metabolite | |
Homocystine is the double-bonded form of homocysteine, but it occurs only transiently before being converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Increasing evidence supports a role for an ele... | |||
T36585 | Isodeoxycholic Acid | isoDCA | Chloride channel , Antibacterial |
Isodeoxycholic Acid is a bile acid that is formed via epimerization of deoxycholic acid by intestinal bacteria. It has a greater critical micelle concentration than DCA, indicating reduced detergent activity, and is less... | |||
T8053 | N-Acetyl-L-arginine | Ac-Arg-OH | Endogenous Metabolite |
N-Acetyl-L-arginine (Ac-Arg-OH) belongs to the class of organic compounds known as n-acyl-l-alpha-amino acids. These are n-acylated alpha amino acids which have the L-configuration of the alpha-carbon atom. N-a-Acetyl-L-... | |||
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カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-00907 | RBP4 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
RBP4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23 kDa and the accession number is P02753. | |||
TMPY-01567 | RBP4 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
RBP4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.8 kDa and the accession number is Q00724. | |||
TMPY-04490 | Carboxypeptidase B2 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
Carboxypeptidase B2 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the accession number is Q9EQV9. | |||
TMPY-01611 | RBP4 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
RBP4 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.8 kDa and the accession number is B2RZC1. | |||
TMPY-02834 | RBP4 Protein, Canine, Recombinant (hFc) | Canine | HEK293 Cells |
RBP4 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48 kDa and the accession number is F1PQI4. | |||
TMPY-02861 | RBP4 Protein, Canine, Recombinant (His) | Canine | HEK293 Cells |
RBP4 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.4 kDa and the accession number is F1PQI4. | |||
TMPY-03591 | RBP4 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
RBP4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.6 kDa. | |||
TMPY-01631 | Carboxypeptidase B2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Carboxypeptidase B2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.4 kDa and the accession number is Q96IY4-1. | |||
TMPY-02505 | Carboxypeptidase B2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Carboxypeptidase B2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the accession number is Q9JHH6. | |||
TMPH-02495 | APMAP Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Exhibits strong arylesterase activity with beta-naphthyl acetate and phenyl acetate. May play a role in adipocyte differentiation. APMAP Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system w... | |||
TMPK-00857 | KLKB1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Plasma kallikrein, also known as Fletcher factor or kallikrein B1 (KLKB1), is a serine endopeptidase, like its homologs tissue kallikrein and kallikrein-related peptidases (KLKs). Its physiological role is to catalyze th... | |||
TMPK-00525 | KLKB1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Plasma kallikrein, also known as Fletcher factor or kallikrein B1 (KLKB1), is a serine endopeptidase, like its homologs tissue kallikrein and kallikrein-related peptidases (KLKs). Its physiological role is to catalyze th... | |||
TMPK-00766 | KLKB1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Plasma kallikrein, also known as Fletcher factor or kallikrein B1 (KLKB1), is a serine endopeptidase, like its homologs tissue kallikrein and kallikrein-related peptidases (KLKs). Its physiological role is to catalyze th... | |||
TMPJ-01393 | PGCP Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Carboxypeptidase Q (Cpq) is a member of the peptidase M28 family. PGCP is involved in a number of fundamental biological processes such as the hydrolysis of circulating peptides, catalyzing the hydrolysis of dipeptides w... | |||
TMPJ-00649 | CPB2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Carboxypeptidase B2 (CPB2) is a secreted enzyme that belongs to the peptidase M14 family. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen by the liver and circulates in the pl... | |||
TMPJ-00084 | RBP4 Protein, Human, Recombinant | Human | E. coli |
Retinol Binding Protein 4 (RBP4) is a member of the Lipocalin family and in the blood. RBP4 is the specific vector for retinol. RBP4 is expressed and secreted by adipose tissue, and is associated with insulin resistance.... | |||
TMPJ-00502 | Serpin G1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. Serpin G1 is a serine protease inhibitor protein... | |||
TMPJ-01064 | Serpin G1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
SERPIN G1 is a member of the serpin family, The C-terminal serpin domain is similar to other serpins, and this part of C1-INH provides the inhibitory activity. SERPIN G1 is involved in the inhibition of the complement sy... | |||
TMPJ-01116 | HABP2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Hyaluronan-binding protein 2(HABP2) is an extracellular serine protease which binds hyaluronic acid. It secreted as an inactive single-chain precursor and is then activated to a heterodimeric form, which consists of a 50... | |||
TMPJ-00490 | Serpin A5 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent i... | |||
TMPH-03024 | MG281 Protein, Mycoplasma genitalium, Recombinant (His) | Mycoplasma genitalium | E. coli |
N/A. MG281 Protein, Mycoplasma genitalium, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 50.6 kDa and the accession number is P47523. | |||
TMPH-03026 | CARDS Protein, Mycoplasma pneumoniae, Recombinant (His & Myc) | Mycoplasma pneumoniae | E. coli |
Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of... | |||
TMPH-03634 | GRA3 Protein, Toxoplasma gondii, Recombinant (His) | Toxoplasma gondii | E. coli |
Direct host-parasite interaction occurs at the cytoplasmic faces of the parasitophorous vacuole membrane (PVM) and the host endoplasmic reticulum (ER) membrane via GRA3 and host CAMLG association. Direct insertion of GRA... | |||
TMPH-03636 | HSP70 Protein, Toxoplasma gondii, Recombinant (His) | Toxoplasma gondii | E. coli |
N/A. HSP70 Protein, Toxoplasma gondii, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 78.9 kDa and the accession number is A0A125YXI9. | |||
TMPH-03632 | GRA1 Protein, Toxoplasma gondii, Recombinant (His) | Toxoplasma gondii | E. coli |
N/A. GRA1 Protein, Toxoplasma gondii, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.9 kDa and the accession number is P13403. | |||
TMPH-03031 | P30 adhesin Protein, Mycoplasma pneumoniae, Recombinant (GST & His) | Mycoplasma pneumoniae | E. coli |
Adhesin necessary for successful cytadherence and virulence. P30 adhesin Protein, Mycoplasma pneumoniae, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular wei... | |||
TMPH-03633 | GRA2 Protein, Toxoplasma gondii, Recombinant (His & Myc) | Toxoplasma gondii | E. coli |
Major granular component involved in excreted-secreted antigen (ESA) immunity. Possibly acts in conjunction with GRA1. GRA2 Protein, Toxoplasma gondii, Recombinant (His & Myc) is expressed in E. coli expression system wi... | |||
TMPH-03025 | VlpE Protein, Mycoplasma hyorhinis, Recombinant (His & Myc) | Mycoplasma hyorhinis | E. coli |
Responsible for the antigenic diversity for host adaptation. Expression in E.coli of a construct containing vlpD, vlpE, and vlpF yields antigenically distinguishable products corresponding to each gene. | |||
TMPH-03033 | P200 Protein, Mycoplasma pneumoniae, Recombinant (His & Myc) | Mycoplasma pneumoniae | E. coli |
Protein cytoskeleton-associated which plays a role in gliding motility and perhaps also in mucociliary clearance. | |||
TMPH-03637 | Profilin Protein, Toxoplasma gondii, Recombinant (E. coli, His) | Toxoplasma gondii | E. coli |
N/A. Profilin Protein, Toxoplasma gondii, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.4 kDa and the accession number is Q58NA1. | |||
TMPH-03028 | HMW3 Protein, Mycoplasma pneumoniae, Recombinant (His & Myc) | Mycoplasma pneumoniae | E. coli |
Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less mycoplasma. This cytoskeleton-like network of accessory proteins containing HMW proteins 1 to 5 allows the proper anchoring of cyta... | |||
TMPH-03027 | HMW1 Protein, Mycoplasma pneumoniae, Recombinant (His & Myc) | Mycoplasma pneumoniae | E. coli |
Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less Mycoplasma. This cytoskeleton-like network of accessory proteins containing HMW proteins 1 to 5 allows the proper anchoring of cyta... | |||
TMPH-03631 | CDPK1 Protein, Toxoplasma gondii, Recombinant (His) | Toxoplasma gondii | E. coli |
N/A. CDPK1 Protein, Toxoplasma gondii, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 63.3 kDa and the accession number is Q9BJF5. | |||
TMPH-03638 | Profilin Protein, Toxoplasma gondii, Recombinant (His) | Toxoplasma gondii | P. pastoris (Yeast) |
N/A. Profilin Protein, Toxoplasma gondii, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 19.4 kDa and the accession number is Q58NA1. | |||
TMPH-03029 | MetAP Protein, Mycoplasma pneumoniae, Recombinant (His & SUMO) | Mycoplasma pneumoniae | E. coli |
Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requ... | |||
TMPH-00017 | AcpS Protein, Acholeplasma laidlawii, Recombinant (His & Myc) | Acholeplasma laidlawii | E. coli |
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. acpS Protein, Acholeplasma laidlawii, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc... | |||
TMPH-03034 | MG218.1 homolog Protein, Mycoplasma pneumoniae, Recombinant (His & Myc) | Mycoplasma pneumoniae | E. coli |
MG218.1 homolog Protein, Mycoplasma pneumoniae, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-03032 | Leucyl aminopeptidase Protein, Mycoplasma pneumoniae, Recombinant (His & SUMO) | Mycoplasma pneumoniae | E. coli |
Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. Leucyl aminopeptidase Protein, Mycoplasma pneumon... | |||
TMPH-03030 | Mgp3 Protein, Mycoplasma pneumoniae, Recombinant (His & Myc) | Mycoplasma pneumoniae | E. coli |
N/A. Mgp3 Protein, Mycoplasma pneumoniae, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 32.5 kDa and the accession number is Q50341. | |||
TMPH-03635 | GRA6 Protein, Toxoplasma gondii, Recombinant (GST) | TOV-Toxoplasma gondii | E. coli |
Major granular component involved in excreted-secreted antigen (ESA) immunity. May have a structural role in the membranous network of the parasitophorous vacuole (PV). GRA6 Protein, Toxoplasma gondii, Recombinant (GST) ... | |||
TMPH-00053 | 50S ribosomal protein L22, Anaplasma phagocytophilum, Recombinant (His & Myc) | Anaplasma phagocytophilum | E. coli |
50S ribosomal protein L22, Anaplasma phagocytophilum, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.2 kDa and the accession number is ... | |||
TMPY-02185 | Coagulation factor XIII B/F13B Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Coagulation factor XIII B chain, also known as Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain and F13B, is a secreted protein which contains 1 Sushi ... | |||
TMPY-00570 | Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyro... | |||
TMPK-00347 | Serum Albumin Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Human serum albumin (HSA), the most prominent protein in plasma, binds different classes of ligands at multiple sites. HSA provides a depot for many compounds, affects pharmacokinetics of many drugs, holds some ligands i... | |||
TMPY-02245 | SNAP-25 Protein, Human, Recombinant (His) | Human | E. coli |
Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains... | |||
TMPY-02292 | IGSF11 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Immunoglobulin superfamily member 11(IGSF11) is expressed on the plasma membrane in the testis and brain. These IGSF proteins undergo final modifications during capacitation and/or the acrosome reaction. IGSF proteins sh... | |||
TMPY-01104 | Coagulation factor XI/F11 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the p... | |||
TMPY-02258 | Kallikrein 3/KLK3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
KLK3 (Kallikrein Related Peptidase 3) is a Protein Coding gene. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease that i... | |||
TMPY-02204 | LBP Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Lipopolysaccharide binding protein ( LBP ) is a glycoprotein that is synthesized principally by hepatocytes. LBP is a trace plasma protein that binds to the lipid A moiety of bacterial lipopolysaccharides ( LPSs ). LBP b... | |||
TMPY-02779 | Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His) | Human | Baculovirus Insect Cells |
Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoant... | |||
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