Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR.
説明 | Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR. |
ターゲット&IC50 | EGFR (T790M):0.37 nM (IC50), EGFR (del19/T790M):0.21 nM (IC50), EGFR (L858R/T790M):0.29 nM (IC50) |
別名 | HS-10296 |
分子量 | 525.64 |
分子式 | C30H35N7O2 |
CAS No. | 1899921-05-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (190.24 mM)
Ethanol: 6 mg/mL (11.41 mM)
H2O: Insoluble
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Almonertinib 1899921-05-1 Angiogenesis JAK/STAT signaling Tyrosine Kinase/Adaptors EGFR inhibit non-small L861Q del19 HER1 mutations L858R lung HS10296 Inhibitor cancer Epidermal growth factor receptor cell HS 10296 HS-10296 ErbB-1 G719X antineoplastic oral NSCLC inhibitor