Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BMY-14802 hydrochloride (BMS 181100 hydrochloride) is a selective antagonist of σ receptor (IC50 = 112 nM) with antipsychotic effects. BMY-14802 hydrochloride is an agonist of the α1-adrenergic receptor and 5-HT1A.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 7,000 | |||
5 mg | 在庫あり | ¥ 16,000 | |||
10 mg | 在庫あり | ¥ 26,000 | |||
25 mg | 在庫あり | ¥ 56,000 | |||
50 mg | 在庫あり | ¥ 95,000 | |||
100 mg | 在庫あり | ¥ 142,000 | |||
500 mg | 在庫あり | ¥ 305,500 |
説明 | BMY-14802 hydrochloride (BMS 181100 hydrochloride) is a selective antagonist of σ receptor (IC50 = 112 nM) with antipsychotic effects. BMY-14802 hydrochloride is an agonist of the α1-adrenergic receptor and 5-HT1A. |
ターゲット&IC50 | σ receptor:112 nM (IC50) |
In vitro | BMY-14802 hydrochloride shows effects on the firing of 5-HTergic and catecholaminergic neurons and affects behaviors in a 5-HT1A-sensitive manner[3]. |
In vivo | Intraperitoneal administration of BMY-14802 hydrochloride (5-20 mg/kg) shows anti-dyskinetic efficacy across a 4-fold dose range against L-DOPA-induced dyskinesias without affecting the efficacy of L-DOPA against lesion-induced akinesia. BMY-14802 hydrochloride reduces D1 and D2 receptor agonist-induced dyskinesias[2]. |
別名 | BMS 181100 hydrochloride, BMY-14802-1, BMY 14802 hydrochloride |
分子量 | 384.85 |
分子式 | C18H23ClF2N4O |
CAS No. | 105565-55-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 9.0 mg/mL (23.4 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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BMY-14802 hydrochloride 105565-55-7 GPCR/G Protein Neuroscience Sigma receptor 5-HT Receptor Adrenergic Receptor BMS 181100 Hydrochloride BMS-181100 Hydrochloride BMS181100 Hydrochloride BMS 181100 hydrochloride BMY-14802-1 BMY14802 Hydrochloride BMY 14802 hydrochloride BMY 14802 Hydrochloride BMY-14802 Hydrochloride Inhibitor inhibitor inhibit