Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Balicatib (AAE581) is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis.
説明 | Balicatib (AAE581) is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis. |
キナーゼ試験 | Cell-free kinase activity assays: Glutathione-S-transferase (GST)-tagged JAK kinase domains expressed in insect cells are purified before use in a peptide substrate phosphorylation assay. Assays are carried out in 384-well optiplates using an Alphascreen Protein Tyrosine Kinase P100 detection kit and a PerkinElmer Fusion Alpha instrument. |
別名 | AAE581 |
分子量 | 411.54 |
分子式 | C23H33N5O2 |
CAS No. | 354813-19-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (121.49 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Balicatib 354813-19-7 Proteases/Proteasome Cysteine Protease AAE581 AAE 581 osteoporosis inhibit AAE-581 Inhibitor bone formation dermal fibroblasts Cathepsin bone turnover inhibitor