Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Clopidogrel hydrogen sulfate ((S)-(+)-Clopidogrel bisulfate) , a selective, high-affinity P2Y12 receptor antagonist, suppressess fibrinogen binding to platelets and platelet adhesion and aggregation.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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25 mg | 在庫あり | ¥ 7,000 | |||
50 mg | 在庫あり | ¥ 9,500 | |||
100 mg | 在庫あり | ¥ 11,500 | |||
200 mg | 在庫あり | ¥ 13,500 | |||
500 mg | 在庫あり | ¥ 18,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,500 |
説明 | Clopidogrel hydrogen sulfate ((S)-(+)-Clopidogrel bisulfate) , a selective, high-affinity P2Y12 receptor antagonist, suppressess fibrinogen binding to platelets and platelet adhesion and aggregation. |
ターゲット&IC50 | CYP2B6:18.2 nM (IC50), CYP2C19:524 nM (IC50) |
In vitro | In a rat model of ulcer margins, daily administration of Clopidogrel (2 mg and 10 mg/kg) significantly reduced the proliferation of gastric epithelial cells induced by ulcers, as well as the expression of the EGF receptor and phosphorylated extracellular signal-regulated kinase. In rats with congestive heart failure, Clopidogrel enhanced the phosphorylation of AKT and eNOS, thereby improving vascular endothelial function and the bioavailability of nitric oxide. |
In vivo | In RGM-1 cells, Clopidogrel (1 μM) inhibits the epidermal growth factor-induced activation of epidermal growth factor receptor, PERK expression, and cellular proliferation. |
別名 | (S)-(+)-Clopidogrel hydrogen sulfate, (S)-(+)-Clopidogrel bisulfate, SR-25990C, Clopidogrel |
分子量 | 419.9 |
分子式 | C16H16ClNO2S·H2SO4 |
CAS No. | 120202-66-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (130.98 mM)
You can also refer to dose conversion for different animals. 詳細
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Clopidogrel hydrogen sulfate 120202-66-6 GPCR/G Protein Metabolism Neuroscience P450 P2Y Receptor Inhibitor Antiplatelet Clopidogrel hydrogen Clopidogrel Bisulfate platelet CYP2C19 CYPs clot antithrombotic (S)-(+)-Clopidogrel hydrogen sulfate Clopidogrel hydrogen Sulfate inhibit aggregation Cytochrome P450 (S)-(+)-Clopidogrel bisulfate blood SR-25990C Clopidogrel CYP2B6 inhibitor