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Platelet aggregation

408

阻害剤

119

天然化合物

リコンビナントタンパク質

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カタログ番号	製品名	別名	ターゲット
T39781	Aβ/tau aggregation-IN-1
	Aβ/tau aggregation-IN-1 is a potent inhibitor of Aβ 1-42 β-sheet formation and tau aggregation. It exhibits K D values of 160 μM and 337 μM with Aβ 1-42 and tau, respectively. Additionally, Aβ/tau aggregation-IN-1 can pe...
T62899	Tau-aggregation and neuroinflammation-IN-1		Microtubule Associated , NO Synthase
	Tau-aggregation and neuroinflammation-IN-1 is a potent inhibitor of tau protein aggregates, showing significant inhibitory activity against AcPHF6 and full-length tau protein aggregates. Tau-aggregation and neuroinflamma...		Microtubule Associated , NO Synthase
T63481	Tau-aggregation-IN-1
	Tau-aggregation-IN-1 is a dopamine D2 and D3 receptor agonist and an inhibitor of tau441 protein aggregation (IC50: 21 μM).
T79038	Tau protein aggregation-IN-1
	Tau Protein Aggregation-IN-1 (Compound 0c) serves as an inhibitor of Tau protein aggregation, applicable in research related to protein folding disorders including Alzheimer's disease, dementia, Parkinson's disease, Hunt...
T78173	Aβ/tau aggregation-IN-3
	Aβ/tau aggregation-IN-3 is a potent inhibitor of amyloid protein aggregation, exhibiting an IC50 value of 0.85 µM in an Aβ-Thioflavin T (Aβ-ThT) functional aggregation assay. This compound demonstrates anti-amyloid activ...
T74811	Tau/Aβ40 aggregation-IN-1
	Tau/Aβ40 aggregation-IN-1 (Compound 20) functions as an inhibitor for tau and Aβ 40 aggregation, exhibiting IC50 values of 1.8 μM and 1.3 μM, respectively [1].
T64238	Aβ1–42 aggregation inhibitor 1
	Aβ1-42 aggregation inhibitor 1 effectively inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), demonstrating IC50 values of 2.64 μM and 1.29 μM, respectively. At a concentration of 25 μM, it also redu...
T14965	Ciliobrevin D		ATPase , Hedgehog/Smoothened
	Ciliobrevin D is a AAA+ ATPase motor cytoplasmic dynein inhibitor. Ciliobrevin D inhibits Hedgehog (Hh) signaling and primary cilia formation and it also inhibits dynein-dependent microtubule gliding and ATPase activity ...		ATPase , Hedgehog/Smoothened
T5036	Cangrelor tetrasodium		GPR , P2Y Receptor
	Cangrelor tetrasodium is a reversible and selective antagonist of platelet P2Y12, with prompt and potent antiplatelet effects.		GPR , P2Y Receptor
T3536	AZD1283		P2Y Receptor
	AZD1283 is an effective P2Y12 receptor antagonist (EC50: 3.0 ug/kg/min, binding IC50: 11 nM). AZD1283 dose-dependently induced increases in blood flow and inhibition of ADP-induced platelet aggregation with antithromboti...		P2Y Receptor
T5460	Mofezolac		COX
	Mofezolac (formerly known as Disopain or N-22) is a highly selective COX-1 (cyclooxygenase-1) inhibitor with COXs selectivity index > 6000		COX
T2065	Bioymifi	DR5 Activator	Apoptosis , TNF
	Bioymifi (DR5 Activator) is a novel and potent small-molecule activator of the TRAIL receptor DR5 in human cancer cells.		Apoptosis , TNF
T6594	MNS		Syk , Src , p97
	MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.		Syk , Src , p97
T2629	UNC2881		TAM Receptor
	UNC2881 is a specific Mer tyrosine kinase inhibitor (IC50: 4.3 nM). It is about 83- and 58-fold higher selectivity than Axl and Tyro3, respectively.		TAM Receptor
T15031	CYM50260		Others , LPL Receptor
	CYM50260 is a potent and exquisitely selective agonist of sphingosine-1-phosphate 4 receptor (S1P4-R, EC50= nM) with no activity against S1P1-R, S1P2-R, S1P3-R and S1P5-R.		Others , LPL Receptor
T6236	Ozagrel	OKY-046,Domenan	Thrombin , Prostaglandin Receptor
	Ozagrel (Domenan) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral isch...		Thrombin , Prostaglandin Receptor
T15047	Dacisteine	N,S-Diacetyl-L-cysteine	Others
	Dacisteine (N,S-Diacetyl-L-cysteine) is an inhibitor of New Delhi metallo-beta-lactamase-1 (NDM-1, IC50 = 1000 μM).		Others
T8719	SC99		Apoptosis , JAK , STAT
	SC99 is a selective inhibitor of JAK2-STAT3 activation. SC99 downregulates the expression of STAT3-modulated genes.SC99 inhibits platelet activation, aggregation and displays potent anti-myeloma, anti-thrombotic activiti...		Apoptosis , JAK , STAT
T1893	Parmodulin 2	ML 161	Protease-activated Receptor
	Parmodulin 2 (ML 161) is the inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50: 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). It also inhibits thromb...		Protease-activated Receptor
T4190	Ticlopidine	PCR 5332,Ticlid	ATPase , Adiponectin receptor
	Ticlopidine (PCR 5332) is an antiplatelet drug in the thienopyridine family which is an adenosine diphosphate (ADP) receptor inhibitor.		ATPase , Adiponectin receptor
T13554	Arimoclomol maleate	BRX-220	HSP
	Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer.		HSP
T0230	Prasugrel	LY640315,CS-747,PCR 4099	P2Y Receptor
	Prasugrel (CS-747) is a piperazine derivative and PLATELET AGGREGATION INHIBITOR that is used to prevent THROMBOSIS in patients with ACUTE CORONARY SYNDROME; UNSTABLE ANGINA and MYOCARDIAL INFARCTION, as well as in those...		P2Y Receptor
T6625	Ozagrel hydrochloride	Ozagrel HCl,OKY-046 HCl	Thrombin , Prostaglandin Receptor
	Ozagrel hydrochloride (OKY-046 HCl) is a selective thromboxane A(2) synthetase inhibitor used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.		Thrombin , Prostaglandin Receptor
T16164	MY-5445	N-(3-chlorophenyl)-4-phenylphthalazin-1-amine	PDE
	MY-5445 (N-(3-chlorophenyl)-4-phenylphthalazin-1-amine) is a specific inhibitor of phosphodiesterase type 5 (PDE5). MY-5445 selectively inhibits cGMP PDE (Ki:1.3 μM).		PDE
T13553	Arimoclomol	BRX-220 free base	HSP
	Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (ALS).		HSP
T2569	Chlorotrianisene	tris(p-methoxyphenyl)chloroethylene,CTA,tri-p-anisylchloroethylene,TACE	Estrogen Receptor/ERR , Estrogen/progestogen Receptor , COX
	Chlorotrianisene (tri-p-anisylchloroethylene) is an orally bioavailable, highly lipophilic, synthetic triphenylethylene (TPE) derivative and selective estrogen receptor modulator (SERM), with predominantly estrogenic but...		Estrogen Receptor/ERR , Estrogen/progestogen Receptor , COX
T22118	NQTrp		Microtubule Associated
	NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.		Microtubule Associated
T0182L	Clopidogrel hydrogen sulfate	(S)-(+)-Clopidogrel hydrogen sulfate,(S)-(+)-Clopidogrel bisulfate,SR-25990C,Clopidogrel	P450 , P2Y Receptor
	Clopidogrel hydrogen sulfate ((S)-(+)-Clopidogrel bisulfate) , a selective, high-affinity P2Y12 receptor antagonist, suppressess fibrinogen binding to platelets and platelet adhesion and aggregation.		P450 , P2Y Receptor
T6952	Prasugrel Hydrochloride	LY 640315,PCR 4099 (hydrochloride),Effient Hydrochloride,LY 640315 Hydrochloride,Prasugrel HCl	P2Y Receptor
	Prasugrel Hydrochloride (LY 640315 Hydrochloride) is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome.		P2Y Receptor
T7003	Leucomethylene blue mesylate	TRx0237 mesylate,TRx0237 (LMTX) mesylate,Methylene blue leuco base mesylate salt,Leucomethylene Blue Dimesylate	Beta Amyloid , Microtubule Associated
	Leucomethylene blue mesylate (TRx0237 mesylate) is a second-generation tau protein aggregation inhibitor for the treatment of Alzheimer's disease (AD) and frontotemporal dementia.		Beta Amyloid , Microtubule Associated
T15757	Limaprost	17α,20-dimethyl-δ2-PGE1,OP1206,ONO1206	PGE Synthase
	Limaprost (17α,20-dimethyl-δ2-PGE1) is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency.It is a potent and orally active vasodilator. Limaprost increases blood...		PGE Synthase
T3757	NQ301		Thrombin , Platelet aggregation
	NQ301, an antithrombotic agent, inhibits collagen-challenged rabbit platelet aggregation (IC50: 10 mg/mL).		Thrombin , Platelet aggregation
T1618	Dipyridamole	Persantin,Dypyridamole,Dipyridamol,NSC-515776,Dipyudamine	PDE
	Dipyridamole (Persantin) is a Platelet Aggregation Inhibitor. The physiologic effect of dipyridamole is by means of Decreased Platelet Aggregation.		PDE
T35161	Xemilofiban	SC-54684A,SC54684A,SC 54684A	Others
	Xemilofiban (SC 54684A) interrupts platelet aggregation, promotes thrombosis, and is used in the study of unstable angina.		Others
T19892	BSBM7		Beta Amyloid
	BSBM7 is an inhibitor of Aβ aggregation and neuronal toxicity.		Beta Amyloid
T6182	Tirofiban	L700462,Aggrastat,MK383	Integrin
	Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.		Integrin
T12857	SC-52012		Others
	SC-52012 is a novel and potent fibrinogen receptor antagonist, an RGD mimetic, which inhibits platelet aggregation.		Others
T13210	Trombodipine	PCA-4230	Antibiotic
	Trombodipine (PCA-4230) is a platelet aggregation inhibitor with antithrombotic activity and protection against Listeria monocytogenes.		Antibiotic
T13368	YLF-466D	C24	AMPK
	YLF-466D (C24) is a newly developed AMPK activator, which inhibits platelet aggregation.		AMPK
T8575	ENFENAMIC ACID		Platelet aggregation
	Enfenamic acid is a platelet aggregation inhibitor and with antirheumatic.		Platelet aggregation
T22932L	LPYFD-NH2 acetate	LPYFD-NH2 acetate (700361-48-4 free base)	Beta Amyloid
	LPYFD-NH2 acetate shows some inhibitory effect on the aggregation of Abeta(1-42).		Beta Amyloid
T63208L	Aβ-IN-1 TFA	Aβ-IN-1 TFA（2766509-32-2 Free base）
	Aβ-IN-1 TFA inhibits and reverses different types of protein aggregation.
T4077	PE859		Beta Amyloid , Gamma-secretase , Microtubule Associated
	PE859 is a potent inhibitor of both tau and Aβ aggregation.		Beta Amyloid , Gamma-secretase , Microtubule Associated
T35262	YM 534	YM-534,YM534	Others
	YM 534 has antitumor activity and platelet aggregation activity, inhibits photoaffinity labeling of deglycosylated P-glycoprotein, and can be used to study leukemia.		Others
T31213	Dazmegrel	UK-38,485,UK 38485,UK 38,485,UK38,485,UK-38485	PPAR
	Dazmegrel (UK 38,485) is a potent and specific thromboxane A2 (TXA2) synthase inhibitor for the prevention of increased whole platelet aggregation in normal pregnancy.		PPAR
T0362	Ticlopidine hydrochloride	Ticlodone,Ticlopidine HCl,Ticlodix	Adenosine Receptor
	Ticlopidine hydrochloride (Ticlodix) is an effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.		Adenosine Receptor
T3608	Carbasalate calcium	Rheomin,Omegin,Alcacyl,Iromin,Solupsan,Carbasalate Calcium	Platelet aggregation
	Carbasalate calcium (Rheomin) is an analgesic, antipyretic, and anti-inflammatory drug, as well as a platelet aggregation inhibitor.		Platelet aggregation
T9887	Ethyl 1-[(4-cyanobenzyl)oxy]-2-(3-cyanophenyl)-4-methyl-1H-imidazole-5-carboxylate		Platelet aggregation
	ethyl 1-[(4-cyanobenzyl)oxy]-2-(3-cyanophenyl)-4-methyl-1H-imidazole-5-carboxylate is a platelet aggregation inhibitor.		Platelet aggregation
TQ0026	MDR-1339	DWK-1339	Beta Amyloid , Gamma-secretase
			Beta Amyloid , Gamma-secretase
T24542	NP-313	NP 313,NSC 4264,NSC-4264,NSC4264
	NP-313 (NSC-4264) is a potent antithrombotic agent that inhibits platelet aggregation and activation by inhibiting thromboxane A 2 synthesis and selectively inhibiting SOCC-mediated Ca2+ efflux.

Compounds

Aβ/tau aggregation-IN-1

T39781

Synonym:

Target:

Tau-aggregation and neuroinflammation-IN-1

T62899

Synonym:

Target: Microtubule Associated, NO Synthase

Tau-aggregation-IN-1

T63481

Synonym:

Target:

Tau protein aggregation-IN-1

T79038

Synonym:

Target:

Aβ/tau aggregation-IN-3

T78173

Synonym:

Target:

tau/Aβ40 aggregation-IN-1

T74811

Synonym:

Target:

Aβ1–42 aggregation inhibitor 1

Target: ATPase, Hedgehog/Smoothened

cangrelor tetrasodium

T5036

Synonym:

Target: GPR, P2Y Receptor

Synonym: DR5 Activator

Target: Apoptosis, TNF

MNS

T6594

Synonym:

Target: Syk, Src, p97

Target: Others, LPL Receptor

Ozagrel

T6236

Synonym: OKY-046,Domenan

Target: Thrombin, Prostaglandin Receptor

Dacisteine

T15047

Synonym: N,S-Diacetyl-L-cysteine

Target: Apoptosis, JAK, STAT

Parmodulin 2

T1893

Synonym: ML 161

Target: Protease-activated Receptor

Ticlopidine

T4190

Synonym: PCR 5332,Ticlid

Target: ATPase, Adiponectin receptor

Synonym: LY640315,CS-747,PCR 4099

Target: P2Y Receptor

Ozagrel hydrochloride

T6625

Synonym: Ozagrel HCl,OKY-046 HCl

Target: Thrombin, Prostaglandin Receptor

MY-5445

T16164

Synonym: N-(3-chlorophenyl)-4-phenylphthalazin-1-amine

Target: PDE

Arimoclomol

T13553

Synonym: BRX-220 free base

Target: HSP

Chlorotrianisene

T2569

Synonym: tris(p-methoxyphenyl)chloroethylene,CTA,tri-p-anisylchloroethylene,TACE

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, COX

NQTrp

T22118

Synonym:

Target: Microtubule Associated

Clopidogrel hydrogen sulfate

T0182L

Synonym: (S)-(+)-Clopidogrel hydrogen sulfate,(S)-(+)-Clopidogrel bisulfate,SR-25990C,Clopidogrel

Target: P450, P2Y Receptor

Prasugrel Hydrochloride

T6952

Synonym: LY 640315,PCR 4099 (hydrochloride),Effient Hydrochloride,LY 640315 Hydrochloride,Prasugrel HCl

Target: P2Y Receptor

Leucomethylene blue mesylate

T7003

Synonym: TRx0237 mesylate,TRx0237 (LMTX) mesylate,Methylene blue leuco base mesylate salt,Leucomethylene Blue Dimesylate

Target: Beta Amyloid, Microtubule Associated

Limaprost

T15757

Synonym: 17α,20-dimethyl-δ2-PGE1,OP1206,ONO1206

Target: Thrombin, Platelet aggregation

Dipyridamole

T1618

Synonym: Persantin,Dypyridamole,Dipyridamol,NSC-515776,Dipyudamine

Target: PDE

Xemilofiban

T35161

Synonym: SC-54684A,SC54684A,SC 54684A

Synonym: L700462,Aggrastat,MK383

Target: Platelet aggregation

LPYFD-NH2 acetate

T22932L

Synonym: LPYFD-NH2 acetate (700361-48-4 free base)

Target: Beta Amyloid

Aβ-IN-1 TFA

T63208L

Synonym: Aβ-IN-1 TFA（2766509-32-2 Free base）

Target: Beta Amyloid, Gamma-secretase, Microtubule Associated

YM 534

T35262

Synonym: YM-534,YM534

Target: Others

Dazmegrel

T31213

Synonym: UK-38,485,UK 38485,UK 38,485,UK38,485,UK-38485

Target: PPAR

Ticlopidine hydrochloride

T0362

Synonym: Ticlodone,Ticlopidine HCl,Ticlodix

Target: Adenosine Receptor

Carbasalate calcium

T3608

Synonym: Rheomin,Omegin,Alcacyl,Iromin,Solupsan,Carbasalate Calcium

Target: Platelet aggregation

ethyl 1-[(4-cyanobenzyl)oxy]-2-(3-cyanophenyl)-4-methyl-1H-imidazole-5-carboxylate

T9887

Synonym:

Target: Platelet aggregation

MDR-1339

TQ0026

Synonym: DWK-1339

Target: Beta Amyloid, Gamma-secretase

NP-313

T24542

Synonym: NP 313,NSC 4264,NSC-4264,NSC4264

Target:

カタログ番号	製品名	別名	ターゲット
TN6919	Methyl tridecanoate		Beta Amyloid , AChE
	Methyl tridecanoate is a natural product.		Beta Amyloid , AChE
T6S0139	Neobavaisoflavone		Apoptosis , DNA/RNA Synthesis
	1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si...		Apoptosis , DNA/RNA Synthesis
T3781	Jujuboside B		Others
	Jujuboside B has potent inhibitory effects on collagen-, thrombin-, AA-, and ADP-induced aggregation, and also exhibits superior protection on the thromboembolic model.		Others
T3S1591	Notoginsenoside Fc		Others , Autophagy
	1. Notoginsenoside Fc has perfect anti-platelet aggregatory effect.		Others , Autophagy
T0853	Adenosine	D-Adenosine,Adenine riboside	Apoptosis , Nucleoside Antimetabolite/Analog , Endogenous Metabolite , Autophagy
	Adenosine (D-Adenosine) is a ribonucleoside comprised of adenine bound to ribose, with vasodilatory, antiarrhythmic and analgesic activities.
TN2244	Sulfuretin		NF-κB , Autophagy
	Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 thr...		NF-κB , Autophagy
T2S2109	Skimmianine	beta-Fagarine,Skimmianin,Chloroxylonine,Skimmiamine	Others
	1. Skimmianine (Chloroxylonine) is a spasmolytic agent. 2. Skimmianine (Chloroxylonine) shows pharmacol. props. similar to 2-(Methylamino)-1-phenyl-1-propanol BCJ45-G.		Others
T5548	Verbenone	2-Pinen-4-one,(-)-Verbenone	Others
	(-)-Verbenone ((-)-Verbenone) is an important component of the essential oil from rosemary. It is also an insect pheromone with a spicy odor and camphoraceous fragrance.		Others
T2230	Paeoniflorin	Peoniflorin	HSP , COX
	Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.		HSP , COX
T1626	Prostaglandin E1	PGE1,Alprostadil	Endogenous Metabolite , Prostaglandin Receptor
	Prostaglandin E1 (Alprostadil) is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Prostaglandin E1 is a potent vasodilator agent that increases peripheral blood flow, in...		Endogenous Metabolite , Prostaglandin Receptor
T1153	Trimethoprim	NIH 204,BW 56-72,NSC-106568	DHFR , DNA/RNA Synthesis , Antifolate , Antibacterial , Antibiotic
	Trimethoprim (NSC-106568) is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor, and Cytochrome P450 2C8 Inhibitor, and Organic Cation Tra...
T3839	Cycloolivil	Isoolivil	Free radical scavengers , Others , Platelet aggregation
	Cycloolivil (Isoolivil) is a natural polyphenolic compound with a significant radical scavenging activity present in olive trees. Cycloolivil has antioxidant activity, it may prevent thrombotic complications associated t...		Free radical scavengers , Others , Platelet aggregation
TN4222	Homoeriodictyol 7-O-β-D-glucoside	Homoeriodictyol 7-O-glucoside	Others , Platelet aggregation
	Homoeriodictyol 7-O-β-D-glucoside (Homoeriodictyol 7-O-glucoside) is a natural product from Viscum coloratum(Kom.)Nakai. Homoeriodictyol 7-O-β-D-glucoside is an antagonist of platelet-activating factor (PAF).		Others , Platelet aggregation
TN6924	Anhydrosafflor yellow B	(2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohexa-1,4-dien-1,AHSYB	Others
	Anhydrosafflor yellow B ((2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,...		Others
T3817	Darutigenol		Others
	Darutigenol has obvious antithrombotic effect, its mechanism may be related to inhibition of platelet aggregation and adhesion.		Others
TN2343	Pseudojervine	Jervin-3-glucoside,O-beta-D-Glucopyranosyljervine	Platelet aggregation
	Pseudojervine (O-beta-D-Glucopyranosyljervine) is derived from Veratrum nigrum L. Pseudojervine exhibits feeble inhibition activity against platelet aggregation.		Platelet aggregation
TQ0036	Anemarrhenasaponin I		Others
	Anemarrhenasaponin I shows the remarkable inhibiting effect on platelet aggregation.		Others
T12164	N6-(4-Hydroxybenzyl)adenosine	Para-topolin riboside	P2Y Receptor
	N6-(4-Hydroxybenzyl)adenosine (Para-topolin riboside) is a platelet aggregation inhibitor.		P2Y Receptor
TN1626	Eugenin		Others
	Eugenin is a chromone isolated from Peucedanum japonicum.Eugenin potent antiplatelet aggregation activity		Others
TN1057	Veratrosine	Veratramine 3-glycoside,Veratramine-beta-D-glucoside	Platelet aggregation
	Veratrosine (Veratramine-beta-D-glucoside) is an alkaloid isolated from the herbs of Veratrum nigrum. Veratrosine exhibits feeble inhibition activity against platelet aggregation.		Platelet aggregation
TN2086	Piperlotine A		Antibacterial
	Piperlotine A is an alkaloid that can be extracted from Piperonyssinus rolfsii and has antiplatelet aggregation activity.Piperlotine A showed inhibition of Mycobacterium tuberculosis in an in vitro assay with a MIC value...		Antibacterial
TN1643	Ferulamide	4-Hydroxy-3-methoxycinnamide	PAFR , AChR
	Ferulamide (4-Hydroxy-3-methoxycinnamide), a Ferulic acid derivative, shows potent inhibitory activity against arachidonic acid-induced platelet aggregation.		PAFR , AChR
T11012	Dextran	Dextran 40	Platelet aggregation
	Dextran has an inhibitory effect on platelet aggregation and coagulation factors, and is used as an agent for increasing plasma volume.		Platelet aggregation
T3734	3',4'-Dihydroxyacetophenone	Qingxintong,4-Acetylpyrocatechol	Tyrosinase , Platelet aggregation
	3',4'-Dihydroxyacetophenone (Qingxintong) is an active constituent of Chinese medicine. It is platelet aggregation Inhibitor and also has anti-arrhythmia activity.		Tyrosinase , Platelet aggregation
T28551	Ro 09-0680	Ro-09-0680,Ro 09 0680
	Ro 09-0680, a compound derived from Salvia miltiorrhiza, is a potent inhibitor of collagen-induced platelet aggregation in rabbits with potential anti-inflammatory activity for the study of cardiovascular disease.
TN2027	Oxysanguinarine	8-Oxosanguinarine,Hydroxysanguinarine	Parasite
	Oxysanguinarine (Hydroxysanguinarine) possesses antiplatelet aggregation activity, it has potential inhibitory properties against the dengue virus.		Parasite
T2898	Andrographolide	Andrographis	SARS-CoV , Influenza Virus , NF-κB , Autophagy
	Andrographolide (Andrographis)(Andrographis), an irreversible antagonist of NF-κB, has anti-inflammatory and anti-platelet aggregation activities and potential antineoplastic.		SARS-CoV , Influenza Virus , NF-κB , Autophagy
TN6710	Methyl acetylsalicylate	ACETYLSALICYLIC ACID METHYL ESTER	Others
	Methyl acetylsalicylate (ACETYLSALICYLIC ACID METHYL ESTER) is a natural product isolated from Pisum sativum. Inhibition of collagen-induced human platelet rich plasma aggregation		Others
T3429	Protopine	Macleyine,Hypercorine,Corydinine,Biflorine,Fumarine	Reactive Oxygen Species , Platelet aggregation , Histamine Receptor
	Protopine (Fumarine) is a benzylisoquinoline alkaloid. It has been found to inhibit histamine H1 receptors and platelet aggregation, and acts as an analgesic.
TN2315	Xanthopurpurin		Platelet aggregation , Antifection
	Xanthopurpurin shows antiviral activity. Xanthopurpurin can effectively inhibit rotavirus multiplication by promoting virus-induced apoptosis in MA-104 cells. Xanthopurpurin shows mainly strong inhibition of collagen-ind...		Platelet aggregation , Antifection
TN1254	3'-Methoxydaidzein		Sodium Channel
	3'-Methoxydaidzein is a dual isoflavone and Sodium Channel inhibitor. 3'-Methoxydaidzein inhibited NaV1.7, NaV1.8 and NaV1.3 with IC50 of 181 nM, 397 nM and 505 nM, respectively. 3'-Methoxydaidzein was specific for colla...		Sodium Channel
T3408	Syringin	Lilacin,Syringoside,eleutheroside-b,Methoxyconiferine	NOS , Autophagy
	Syringin (eleutheroside-b) is a compound with antitumor, antiproliferative, immunomodulatory and platelet aggregation inhibiting effects.		NOS , Autophagy
T5810	TABERSONINE HYDROCHLORIDE		Beta Amyloid
	TABERSONINE HYDROCHLORIDE is a natural product extracted from the bean of Voacanga africana, is a potent inhibitor against Aβ(1 42) aggregation and toxicity.		Beta Amyloid
T1723	Adenosine 5'-diphosphate	Adenosine diphosphate,adenosine pyrophosphate,ADP	Endogenous Metabolite
	Adenosine 5'-diphosphate (ADP) induces human platelet aggregation and non-competitively blocks the stimulated human platelet adenylate cyclase.		Endogenous Metabolite
T4S1658	Benzoyloxypaeoniflorin	Benzoyloxypeoniflorin	NF-κB , Tyrosinase
	Benzoyloxypaeoniflorin (Benzoyloxypeoniflorin) is a natural product,contributes to improving blood circulation through their inhibitory effects on both platelet aggregation and blood coagulation.		NF-κB , Tyrosinase
T5725	Salvianolic acid B	lithospermic acid B,Dan Shen Suan B	Sirtuin , Autophagy
	Salvianolic acid B is a water-soluble antioxidant from Salvia extract. Salvianolic acid B plays significant role of antioxidant effect; antiplatelet aggregation, anticoagulant, and antithrombotic effect.		Sirtuin , Autophagy
T2745	18α-Glycyrrhetinic acid	Enoxolone,Glycyrrhetinic acid	Apoptosis , NF-κB , Proteasome
	18α-Glycyrrhetinic acid (Enoxolone) is an inhibitor of NF-kB and an activator of the proteasome, and functions as a longevity-promoting and anti-aggregation factor in multicellular organisms. It induces apoptosis.		Apoptosis , NF-κB , Proteasome
T2S1749	Protogracillin		Others
	Protogracillin may have inhibitions on platelet aggregation (PAG) and thrombosis.		Others
T2727	Salvianolic acid B		Others
	Salvianolic acid B (Dan Shen Suan B) is a water-soluble antioxidant from Salvia extract. It plays significant role of antioxidant effect; antiplatelet aggregation, anticoagulant, and antithrombotic effect		Others
T0131	Cepharanthine	NSC-623442	Apoptosis , TNF , HIV Protease , Autophagy
	Cepharanthine (NSC-623442), a biscoclaurine alkaloid, suppresses tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and inhibits cytokine production.		Apoptosis , TNF , HIV Protease , Autophagy
TN1564	Delphinidin 3-glucoside chloride	Delphinidin-3-O-glucoside chloride	Apoptosis , EGFR
	Delphinidin 3-glucoside chloride (Delphinidin-3-O-glucoside chloride) is a dietary phenolic substance found in Hibiscus sabdariffa extracts. Delphinidin 3-glucoside chloride has antioxidant activity, induces pro-apoptoti...		Apoptosis , EGFR
TN1341	8-Deoxygartanin		Beta Amyloid , NF-κB , Parasite
	8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor, it exhibits significant inhibition of self-induced α2-amyloid (Aα2) aggregation, it has multifunctional activities against Alzheimer's disease (AD) a...		Beta Amyloid , NF-κB , Parasite
TL0001	Dencichine	L-Dencichin,ODAP,Dencichin	Others , HIF/HIF Prolyl-Hydroxylase
	Dencichine (ODAP) is a neurotoxic agent. Dencichine is a haemostatic agent, the hemostatic effect relates to modulation of the coagulation system, platelet aggregation and fibrinolytic system. It has renoprotective effec...		Others , HIF/HIF Prolyl-Hydroxylase
T0070	Pentoxifylline	Oxpentifylline,PTX,BL-191	HIV Protease , PDE , Adenosine Receptor , Autophagy
	Pentoxifylline (PTX) modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodiesterase and affects blood rheology. It also inhibits platelet ...		HIV Protease , PDE , Adenosine Receptor , Autophagy
T3S0645	N-trans-Feruloyltyramine	Feruloyltyramine,N-Feruloyltyramine,Moupinamide	Others , COX
	1. N-trans-Feruloyltyramine (Feruloyltyramine)(NTF) has hepatoprotective effect. 2. NTF has antioxidative activity against Aβ(1-42)-induced neuronal death. 3. NTF is likely to inhibit COX enzymes, thereby suppressing P-s...		Others , COX
T7030	Anemarsaponin B		p38 MAPK , NF-κB , MEK , COX , NO Synthase
	Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity, possibly via the p38 MAP kinase pathway. Anemarsaponin B c...		p38 MAPK , NF-κB , MEK , COX , NO Synthase
TN1170	1-Cinnamoylpyrrolidine		Platelet aggregation
	1-Cinnamoylpyrrolidine, a natural product prepared from Piper caninum, can be used as a DNA strand breaking agent, inducing the relaxation of the plasmid pBR322 DNA superhelix in the presence of Cu2+. 1-Cinnamoylpyrrolid...		Platelet aggregation
TN6975	Cirsiumaldehyde	5,5’-oxydimethylenebis(2-furfural)	Platelet aggregation
	Cirsiumaldehyde is a compound isolated from the mature fruits of Lobelia chinensis, Cornus officinalis, and the fruits of Hippophae rhamnoides.Cirsiumaldehyde in the presence of collagen inhibited U46619-induced (1~5 uM)...		Platelet aggregation
T3427	Polydatin	Piceid,Polydotin Peceid	Apoptosis , Mitophagy , NF-κB , Autophagy
	Polydatin (Piceid), the glycoside of Resveratrol, is originally isolated from the Chinese herb Polygonum cuspidatum. The compound can inhibit platelet aggregation and elevate the ratios of LDL-C/HDL-C and TC/HDL-C. In th...		Apoptosis , Mitophagy , NF-κB , Autophagy
TN1622	Ermanin		NOS , Influenza Virus , COX , HIV Protease , Antibacterial , Antibiotic
	Ermanin is a flavonoid isolated from Tanacetum microphyllum.Ermanin inhibits platelet aggregation and has anti-tuberculosis and anti-viral/bacterial properties.Ermanin has anti-inflammatory activity by inhibiting the exp...
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天然物製品

Methyl tridecanoate

TN6919

Synonym:

Target: Beta Amyloid, AChE

Neobavaisoflavone

T6S0139

Synonym:

Target: Apoptosis, DNA/RNA Synthesis

Target: Others, Autophagy

Adenosine

T0853

Synonym: D-Adenosine,Adenine riboside

Target: Apoptosis, Nucleoside Antimetabolite/Analog, Endogenous Metabolite, Autophagy

Sulfuretin

TN2244

Synonym:

Target: NF-κB, Autophagy

Skimmianine

T2S2109

Synonym: beta-Fagarine,Skimmianin,Chloroxylonine,Skimmiamine

Target: Others

Verbenone

T5548

Synonym: 2-Pinen-4-one,(-)-Verbenone

Synonym: PGE1,Alprostadil

Target: Endogenous Metabolite, Prostaglandin Receptor

Trimethoprim

T1153

Synonym: NIH 204,BW 56-72,NSC-106568

Target: DHFR, DNA/RNA Synthesis, Antifolate, Antibacterial, Antibiotic

Cycloolivil

T3839

Synonym: Isoolivil

Target: Free radical scavengers, Others, Platelet aggregation

Homoeriodictyol 7-O-β-D-glucoside

TN4222

Synonym: Homoeriodictyol 7-O-glucoside

Target: Others, Platelet aggregation

Anhydrosafflor yellow B

TN6924

Synonym: (2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohexa-1,4-dien-1,AHSYB

Synonym: Jervin-3-glucoside,O-beta-D-Glucopyranosyljervine

Target: Platelet aggregation

N6-(4-Hydroxybenzyl)adenosine

T12164

Synonym: Para-topolin riboside

Synonym: Veratramine 3-glycoside,Veratramine-beta-D-glucoside

Target: Platelet aggregation

Piperlotine A

TN2086

Synonym:

Target: Antibacterial

Ferulamide

TN1643

Synonym: 4-Hydroxy-3-methoxycinnamide

Target: Platelet aggregation

3',4'-Dihydroxyacetophenone

T3734

Synonym: Qingxintong,4-Acetylpyrocatechol

Target: Tyrosinase, Platelet aggregation

Ro 09-0680

T28551

Synonym: Ro-09-0680,Ro 09 0680

Target:

Oxysanguinarine

TN2027

Synonym: 8-Oxosanguinarine,Hydroxysanguinarine

Target: Parasite

Andrographolide

T2898

Synonym: Andrographis

Target: SARS-CoV, Influenza Virus, NF-κB, Autophagy

Methyl acetylsalicylate

TN6710

Synonym: ACETYLSALICYLIC ACID METHYL ESTER

Target: Others

Protopine

T3429

Synonym: Macleyine,Hypercorine,Corydinine,Biflorine,Fumarine

Target: Reactive Oxygen Species, Platelet aggregation, Histamine Receptor

Xanthopurpurin

TN2315

Synonym:

Target: Platelet aggregation, Antifection

3'-Methoxydaidzein

TN1254

Synonym:

Target: Sodium Channel

Syringin

T3408

Synonym: Lilacin,Syringoside,eleutheroside-b,Methoxyconiferine

Target: NOS, Autophagy

TABERSONINE HYDROCHLORIDE

T5810

Synonym:

Target: Beta Amyloid

Adenosine 5'-diphosphate

T1723

Synonym: Adenosine diphosphate,adenosine pyrophosphate,ADP

Target: Endogenous Metabolite

Benzoyloxypaeoniflorin

T4S1658

Synonym: Benzoyloxypeoniflorin

Target: NF-κB, Tyrosinase

Salvianolic acid B

T5725

Synonym: lithospermic acid B,Dan Shen Suan B

Target: Sirtuin, Autophagy

18α-Glycyrrhetinic acid

T2745

Synonym: Enoxolone,Glycyrrhetinic acid

Target: Apoptosis, NF-κB, Proteasome

Target: Apoptosis, TNF, HIV Protease, Autophagy

Delphinidin 3-glucoside chloride

TN1564

Synonym: Delphinidin-3-O-glucoside chloride

Target: Apoptosis, EGFR

8-Deoxygartanin

TN1341

Synonym:

Target: Beta Amyloid, NF-κB, Parasite

dencichine

TL0001

Synonym: L-Dencichin,ODAP,Dencichin

Target: Others, HIF/HIF Prolyl-Hydroxylase

Pentoxifylline

T0070

Synonym: Oxpentifylline,PTX,BL-191

Target: HIV Protease, PDE, Adenosine Receptor, Autophagy

N-trans-Feruloyltyramine

T3S0645

Synonym: Feruloyltyramine,N-Feruloyltyramine,Moupinamide

Target: p38 MAPK, NF-κB, MEK, COX, NO Synthase

1-Cinnamoylpyrrolidine

TN1170

Synonym:

Target: Platelet aggregation

Cirsiumaldehyde

TN6975

Synonym: 5,5’-oxydimethylenebis(2-furfural)

Target: Platelet aggregation

Polydatin

T3427

Synonym: Piceid,Polydotin Peceid

Target: Apoptosis, Mitophagy, NF-κB, Autophagy

Ermanin

TN1622

Synonym:

Target: NOS, Influenza Virus, COX, HIV Protease, Antibacterial, Antibiotic

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-00624	PEAR1 Protein, Rat, Recombinant (His)	Rat	Baculovirus Insect Cells
	Platelet endothelial aggregation receptor-1 (PEAR1), an epidermal growth factor repeat-containing transmembrane receptor, is known to participate in platelet contact-induced activation. Platelet endothelial aggregation r...
TMPH-00213	Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc)	Bothrops atrox	E. coli
	Inhibits fibrinogen interaction with platelets. Acts by binding to the glycoprotein IIb-IIIa receptor (ITGA2B/ITGB3) on the platelet surface and inhibits aggregation induced by ADP, thrombin, platelet-activating factor a...
TMPY-00545	Dermcidin Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Hepatocellular carcinoma (HCC) is a major contributor to cancer-related deaths due to its often late stage diagnosis, and dermcidin (DCD) may have the potential to be used as a serum biomarker for HCC for more timely dia...
TMPY-04830	GAS6 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin ...
TMPY-02521	HIST3H2A Protein, Human, Recombinant	Human	E. coli
	Histones are a complex family of highly conserved basic proteins responsible for packaging chromosomal DNA into nucleosomes. There are subtype diversities: H1, H2A, H2B, and H3 or H4. It has become more and more evident ...
TMPH-00320	Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His)	Calloselasma rhodostoma	P. pastoris (Yeast)
	Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen ...
TMPH-00322	Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His)	Calloselasma rhodostoma	P. pastoris (Yeast)
	Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen ...
TMPH-00323	Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His & Myc)	Calloselasma rhodostoma	E. coli
	Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen ...
TMPH-00321	Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His & SUMO)	Calloselasma rhodostoma	E. coli
	Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen ...
TMPH-01603	Lanosterol synthase/LSS Protein, Human, Recombinant (His)	Human	E. coli
	Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens prote...
TMPH-03283	CD39 Protein, Rat, Recombinant (His)	Rat	Baculovirus Insect Cells
	In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP....
TMPH-02851	PDIA2 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded protei...
TMPJ-01124	PDIA6 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Protein Disulfide-Isomerase A6 (PDIA6) is a 48.5kDa protein that belongs to the protein disulfide isomerase family (PDI). PDIA6 is an enzyme in the endoplasmic reticulum in eukaryotes which catalyzes the formation and br...
TMPH-03284	CD39 Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
	In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP....
TMPH-00216	SVMP Protein, Bothrops jararaca, Recombinant (His & KSI)	Bothrops jararaca	E. coli
	Metalloproteinase that binds to von Willebrand factor (VWF) and induces its interaction with GPIb (GP1BA), resulting in platelet aggregation. SVMP Protein, Bothrops jararaca, Recombinant (His & KSI) is expressed in E. co...
TMPH-00083	Dehydrin ERD14 Protein, Arabidopsis thaliana, Recombinant (His & Myc)	Arabidopsis thaliana	E. coli
	Intrinsically disordered protein acting as a chaperone. Prevents heat-induced aggregation and/or inactivation of various substrates. Binds to acidic phospholipid vesicles without affecting membrane fluidity. Dehydrin ERD...
TMPH-01822	P2Y1 Protein, Human, Recombinant (His)	Human	E. coli
	Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately p...
TMPH-00215	SVTLE Protein, Bothrops jararaca, Recombinant (His & Myc)	Bothrops jararaca	E. coli
	Thrombin-like snake venom serine protease that clots fibrinogen by releasing fibrinopeptide A from the alpha chain of fibrinogen (FGA), induces platelet aggregation through its interaction with GPIb (GP1BA/GP1BB), and ac...
TMPH-03121	CXCL4 Protein, Pig, Recombinant (His & Myc)	Sus scrofa (Pig)	E. coli
	Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophil...
TMPJ-00734	KNG1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Kininogen-1 is a secreted protein which contains three cystatin domains. There are two alternatively spliced forms, designated as the high molecular weight (HMW) and low MW (LMW) forms. Kininogen-1 plays a critical role ...
TMPH-02571	CD9 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion. Present at the cell surface of oocytes and plays...
TMPH-03600	Glucosyltransferase-SI Protein, S. mutans serotype c, Recombinant (His & Myc)	Streptococcus mutans	E. coli
	Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and fo...
TMPK-01552	HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell prolifer...
TMPK-01532	HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell prolifer...
TMPK-01508	HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell prolifer...
TMPK-01531	HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell prolifer...
TMPK-01442	HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled	Human	HEK293 Cells
	p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell prolifer...
TMPK-01509	HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell prolifer...
TMPK-01538	HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell prolifer...
TMPK-01437	HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled	Human	HEK293 Cells
	p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell prolifer...
TMPJ-00754	CRYAA Protein, Human, Recombinant (His)	Human	E. coli
	Alpha-Crystallin A Chain (CRYAA) belongs to the small heat shock protein (HSP20) family and can be induced by heat shock. The expression of CRYAA is preferentially restricted to the lens cell. CRYAA may contribute to the...
TMPJ-00766	ANXA1 Protein, Human, Recombinant	Human	E. coli
	Annexin A1 is the first characterized member of the annexin family of proteins and is able to bind to cellular membranes in a calcium-dependent manner, promoting membrane fusion and endocytosis. Annexin A1 has anti-infla...
TMPH-00331	ALS3 Protein, Candida albicans, Recombinant (B2M & His & Myc)	Candida albicans	E. coli
	Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the biofilm formation and pathogenesis of C.albicans infections. Necessary for C.albicans...
TMPH-02997	Dps Protein, Mycobacterium smegmatis, Recombinant (His & SUMO)	Mycobacterium smegmatis	E. coli
	Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical produ...
TMPH-00217	SVMP Protein, Bothrops leucurus, Recombinant (His & Myc)	Bothrops leucurus	E. coli
	Non-hemorrhagic metalloproteinase that hydrolyzes the alpha chains of fibrinogen, as well as fibrin, fibronectin and casein. Beta and gamma chains are also hydrolyzed, but more slowly. Thrombolytic activity is also obser...
TMPJ-00915	HSP40 Protein, Human, Recombinant (His)	Human	E. coli
	DnaJ Homolog Subfamily B Member 1 (DNAJB1) is a member of the heat shock protein family. Heat shock proteins (HSPs) are a highly conserved family of stress response proteins. HSPs function primarily as molecular chaperon...
TMPY-04336	Orange fluorescent protein Protein, Discosoma sp, Recombinant (His)	Discosoma sp	E. coli
	OFPSparkTM is a red (orange) fluorescent protein (excitation/emission maxima are 549 and 566 nm, respectively) derived from DsRed. Possessing high photostability and pH stability, OFPSparkTM is more than twice brighter t...
TMPJ-00523	SAA2 Protein, Human, Recombinant (His)	Human	E. coli
	Serum amyloid A-2 protein (SAA2) belongs to the SAA family. It expressed by the liver and secreted in plasma. SAA2 functions as major acute phase reactant and could works as apolipoprotein of the HDL complex. Increased l...
TMPY-02499	Cofilin 2 Protein, Human, Recombinant (His)	Human	E. coli
	Cofilin 2 (muscle), also known as CFL2, is a member of cofilin family of the actin-binding protein superfamily. Cofilin2 shows significant homology to the other two members: cofilin 1 and DSTN, through its entire sequenc...
TMPJ-01411	HSPB11 Protein, Human, Recombinant (His)	Human	E. coli
	Heat Shock Protein β-11 (HSPB11) is a stress-responsive protein that is required to deal with proteotoxic stresses. HSPB11 is composed of an IFT complex B composed of IFT88, IFT57, TRAF3IP1, IFT52, IFT27, HSPB11 and IFT2...
TMPJ-00045	Podoplanin Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Podoplanin is a type-1 transmembrane protein that belongs to Podoplanin family. PDPN expressed in various specialized cell types throughout the body. It highly expressed in placenta, lung, skeletal muscle and brain, weak...
TMPH-00672	Metalloprotease stcE Protein, E. coli O157:H7, Recombinant (His)	E. coli	E. coli
	Virulence factor that contributes to intimate adherence of enterohemorrhagic E.coli (EHEC) O157:H7 to host cells. Is able to cleave the secreted human mucin 7 (MUC7) and the glycoprotein 340 (DMBT1/GP340). Also cleaves h...
TMPJ-00534	HFcgR4 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Fcgr4, also known as CD16-2, is one of the receptors for Fc region of IgG which involve in immune responses. Fcgr4 mainly functions in cellular response to lipopolysaccharide, NK T cell proliferation, regulation of senso...
TMPY-02977	PDE1C Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	PDE1C belongs to the cyclic nucleotide phosphodiesterase family, PDE1 subfamily. Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3' cyclic phosphate bonds ...
TMPJ-01143	MERTK/Mer Protein, Human, Recombinant (aa 1-323, His)	Human	HEK293 Cells
	Tyrosine-protein kinase Mer (MERTK) is a single-pass type I membrane protein which belongs to the MER/AXL/TYRO3 receptor kinase family. MERTK include two fibronectin type-III domains, two Ig-like C2-type domains, and one...
TMPY-02081	PDE2A Protein, Human, Recombinant (aa 215-900, His)	Human	Baculovirus Insect Cells
	cGMP-dependent 3',5'-cyclic phosphodiesterase, also known as cyclic GMP-stimulated phosphodiesterase and PDE2A, is a peripheral membrane protein that belongs to the cyclic nucleotide phosphodiesterase family and PDE2 sub...
TMPY-00741	CXCL4 Protein, Human, Recombinant	Human	E. coli
	Platelet factor 4 (PF4), also known as chemokine (C-X-C motif) ligand 4 (CXCL4), is a small cytokine belonging to the CXC chemokine family. CXCL4/PF4 is released from the alpha-granules of activated platelets and binds w...
TMPJ-00605	GPVI Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Glycoprotein VI (GPVI) is a 63 kDa platelet/megakaryocyte-specific type I transmembrane glycoprotein of the immunoglobulin superfamily that is an important collagen receptor and initiator of platelet activation, aggregat...
TMPY-04414	MUSK Protein, Human, Recombinant (aa 433-783, His & GST)	Human	Baculovirus Insect Cells
	Muscle, skeletal receptor tyrosine-protein kinase, also known as Muscle-specific tyrosine-protein kinase receptor, Muscle-specific kinase receptor, and MUSK, is a single-pass type I membrane protein that belongs to the p...
TMPH-01664	OMA1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Activated in response to various mitochondrial stress, leading to the proteolytic cleavage of target proteins, such as OPA...
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PEAR1 Protein, Rat, Recombinant (His)

TMPY-00624

Species: Rat

Expression System: Baculovirus Insect Cells

Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc)

TMPH-00213

Species: Bothrops atrox

Expression System: E. coli

Dermcidin Protein, Human, Recombinant (hFc)

TMPY-00545

Species: Human

Expression System: HEK293 Cells

GAS6 Protein, Mouse, Recombinant (His)

TMPY-04830

Species: Mouse

Expression System: HEK293 Cells

HIST3H2A Protein, Human, Recombinant

TMPY-02521

Species: Human

Expression System: E. coli

Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His)

TMPH-00320

Species: Calloselasma rhodostoma

Expression System: P. pastoris (Yeast)

Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His)

TMPH-00322

Species: Calloselasma rhodostoma

Expression System: P. pastoris (Yeast)

Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His & Myc)

TMPH-00323

Species: Calloselasma rhodostoma

Expression System: E. coli

Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His & SUMO)

TMPH-00321

Species: Calloselasma rhodostoma

Expression System: E. coli

Lanosterol synthase/LSS Protein, Human, Recombinant (His)

TMPH-01603

Species: Human

Expression System: E. coli

CD39 Protein, Rat, Recombinant (His)

TMPH-03283

Species: Rat

Expression System: Baculovirus Insect Cells

PDIA2 Protein, Mouse, Recombinant (His & SUMO)

TMPH-02851

Species: Mouse

Expression System: E. coli

PDIA6 Protein, Human, Recombinant (His)

TMPJ-01124

Species: Human

Expression System: HEK293 Cells

CD39 Protein, Rat, Recombinant (E. coli, His)

TMPH-03284

Species: Rat

Expression System: E. coli

SVMP Protein, Bothrops jararaca, Recombinant (His & KSI)

TMPH-00216

Species: Bothrops jararaca

Expression System: E. coli

Dehydrin ERD14 Protein, Arabidopsis thaliana, Recombinant (His & Myc)

TMPH-00083

Species: Arabidopsis thaliana

Expression System: E. coli

P2Y1 Protein, Human, Recombinant (His)

TMPH-01822

Species: Human

Expression System: E. coli

SVTLE Protein, Bothrops jararaca, Recombinant (His & Myc)

TMPH-00215

Species: Bothrops jararaca

Expression System: E. coli

CXCL4 Protein, Pig, Recombinant (His & Myc)

TMPH-03121

Species: Sus scrofa (Pig)

Expression System: E. coli

KNG1 Protein, Human, Recombinant (His)

TMPJ-00734

Species: Human

Expression System: HEK293 Cells

CD9 Protein, Mouse, Recombinant (His)

TMPH-02571

Species: Mouse

Expression System: E. coli

Glucosyltransferase-SI Protein, S. mutans serotype c, Recombinant (His & Myc)

TMPH-03600

Species: Streptococcus mutans

Expression System: E. coli

HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi), Biotinylated

TMPK-01552

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi)

TMPK-01532

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein, Human, MHC (His & Avi)

TMPK-01508

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein, Human, MHC (His & Avi)

TMPK-01531

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

TMPK-01442

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Monomer Protein, Human, MHC (His & Avi)

TMPK-01509

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Monomer Protein, Human, MHC (His & Avi), Biotinylated

TMPK-01538

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

TMPK-01437

Species: Human

Expression System: HEK293 Cells

CRYAA Protein, Human, Recombinant (His)

TMPJ-00754

Species: Human

Expression System: E. coli

ANXA1 Protein, Human, Recombinant

TMPJ-00766

Species: Human

Expression System: E. coli

ALS3 Protein, Candida albicans, Recombinant (B2M & His & Myc)

TMPH-00331

Species: Candida albicans

Expression System: E. coli

Dps Protein, Mycobacterium smegmatis, Recombinant (His & SUMO)

TMPH-02997

Species: Mycobacterium smegmatis

Expression System: E. coli

SVMP Protein, Bothrops leucurus, Recombinant (His & Myc)

TMPH-00217

Species: Bothrops leucurus

Expression System: E. coli

HSP40 Protein, Human, Recombinant (His)

TMPJ-00915

Species: Human

Expression System: E. coli

Orange fluorescent protein Protein, Discosoma sp, Recombinant (His)

TMPY-04336

Species: Discosoma sp

Expression System: E. coli

SAA2 Protein, Human, Recombinant (His)

TMPJ-00523

Species: Human

Expression System: E. coli

Cofilin 2 Protein, Human, Recombinant (His)

TMPY-02499

Species: Human

Expression System: E. coli

HSPB11 Protein, Human, Recombinant (His)

TMPJ-01411

Species: Human

Expression System: E. coli

Podoplanin Protein, Human, Recombinant (hFc)

TMPJ-00045

Species: Human

Expression System: HEK293 Cells

Metalloprotease stcE Protein, E. coli O157:H7, Recombinant (His)

TMPH-00672

Species: E. coli

Expression System: E. coli

hFcgR4 Protein, Mouse, Recombinant (His)

TMPJ-00534

Species: Mouse

Expression System: HEK293 Cells

PDE1C Protein, Human, Recombinant (His & GST)

TMPY-02977

Species: Human

Expression System: Baculovirus Insect Cells

MERTK/Mer Protein, Human, Recombinant (aa 1-323, His)

TMPJ-01143

Species: Human

Expression System: HEK293 Cells

PDE2A Protein, Human, Recombinant (aa 215-900, His)

TMPY-02081

Species: Human

Expression System: Baculovirus Insect Cells

CXCL4 Protein, Human, Recombinant

TMPY-00741

Species: Human

Expression System: E. coli

GPVI Protein, Mouse, Recombinant (His)

TMPJ-00605

Species: Mouse

Expression System: HEK293 Cells

MUSK Protein, Human, Recombinant (aa 433-783, His & GST)

TMPY-04414

Species: Human

Expression System: Baculovirus Insect Cells

OMA1 Protein, Human, Recombinant (His & SUMO)

TMPH-01664

Species: Human

Expression System: E. coli

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カタログ番号	製品名
L5400	Anti-Cardiovascular Disease Compound Library	1408 compounds
	A unique collection of 1408 cardiovascular diseases related compounds for high throughput screening (HTS) and high content screening (HCS);
L8710	Cuproptosis Compound Library	400 compounds
	TargetMol’s Cuproptosis Compound Library is a collection of 400 compounds related to copper-dependent death that can be used to study its mechanism and related diseases.

ライブラリー

Anti-Cardiovascular Disease Compound Library

L5400

Compounds: 1408

Cuproptosis Compound Library

L8710

Compounds: 400