Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Difamilast is a selective inhibitor of phosphodiesterase-4 (PDE4) with particularly efficient inhibition of subtype B (IC50=11.2 nM).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 30,500 | |||
5 mg | 在庫あり | ¥ 75,500 | |||
10 mg | 在庫あり | ¥ 121,500 | |||
25 mg | 在庫あり | ¥ 197,500 | |||
50 mg | 在庫あり | ¥ 273,500 | |||
100 mg | 在庫あり | ¥ 363,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 83,500 |
説明 | Difamilast is a selective inhibitor of phosphodiesterase-4 (PDE4) with particularly efficient inhibition of subtype B (IC50=11.2 nM). |
ターゲット&IC50 | PDE4B:11.2 nM |
In vitro | Difamilast exerts inhibitory effects on PDE2[1]. |
In vivo | In relevant animal models of AD, Difamilast improves skin condition [3]. |
分子量 | 446.44 |
分子式 | C23H24F2N2O5 |
CAS No. | 937782-05-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (223.99 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Difamilast 937782-05-3 Metabolism PDE PDE4 OPA 15406 Inhibitor atopic phosphodiesterase-4 OPA15406 Phosphodiesterase (PDE) OPA-15406 dermatitis subtype inhibit inhibitor