Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GSK-LSD1 dihydrochloride (GSK-LSD1 2HCl) is a specificity irreversible LSD1 inhibitor (IC50: 16 nM). The selectivity of GSK-LSD1 for LSD1 is >1000 fold over other closely related FAD utilizing enzymes (i.e. MAO-A, LSD2, MAO-B).
説明 | GSK-LSD1 dihydrochloride (GSK-LSD1 2HCl) is a specificity irreversible LSD1 inhibitor (IC50: 16 nM). The selectivity of GSK-LSD1 for LSD1 is >1000 fold over other closely related FAD utilizing enzymes (i.e. MAO-A, LSD2, MAO-B). |
ターゲット&IC50 | LSD1:16 nM |
In vitro | GSK-LSD1 induces gene expression changes in cancer cell lines with average EC50 of < 5 nM and inhibits cancer cell line growth with average EC50 of < 5 nM. [1] |
別名 | GSK-LSD1 (hydrochloride), GSK-LSD1 2HCl |
分子量 | 289.24 |
分子式 | C14H22Cl2N2 |
CAS No. | 2102933-95-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4.23 mg/mL (14.63 mM), Sonication is recommended.
H2O: 10 mg/mL (34.57 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
GSK-LSD1 dihydrochloride 2102933-95-7 Chromatin/Epigenetic Histone Demethylase GSK LSD1 dihydrochloride GSK-LSD1 Dihydrochloride Monoamine Oxidase GSK-LSD-1 dihydrochloride Inhibitor GSK-LSD1 (hydrochloride) GSK-LSD1 2HCl inhibit MAO GSKLSD1 dihydrochloride GSK-LSD1 inhibitor