Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endothelial cell proliferation.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 13,000 | |||
10 mg | 在庫あり | ¥ 22,500 | |||
25 mg | 在庫あり | ¥ 51,000 | |||
50 mg | 在庫あり | ¥ 91,500 | |||
100 mg | 在庫あり | ¥ 135,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 14,000 |
説明 | JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endothelial cell proliferation. |
ターゲット&IC50 | VEGFR2:7.8 μM |
分子量 | 323.35 |
分子式 | C18H17N3O3 |
CAS No. | 942655-44-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (185.56 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
JK-P3 942655-44-9 Angiogenesis Tyrosine Kinase/Adaptors VEGFR Inhibitor HUVEC Anti-angiogenesis FGFR JK P3 Fibroblast growth factor receptor JKP3 Anti-cancer inhibit Endothelial cells JK-P-3 Vascular endothelial growth factor receptor inhibitor