Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction. It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake
説明 | MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction. It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake |
分子量 | 293.3 |
分子式 | C12H11N3O4S |
CAS No. | 312608-54-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 31.25 mg/mL (106.55 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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MID-1 312608-54-1 Others Tyrosine Kinase/Adaptors IGF-1R inhibit MID 1 Inhibitor MG53 ubiquitination MID1 Insulin Receptor insulin association glucose IRS-1 degradation inhibitor