Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Metyrapone (NSC-25265) is an inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
説明 | Metyrapone (NSC-25265) is an inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME. |
ターゲット&IC50 | 11β-HSD1:30 μM(Ki) |
別名 | NSC-25265, Su-4885 |
分子量 | 226.27 |
分子式 | C14H14N2O |
CAS No. | 54-36-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 203.3 mM
You can also refer to dose conversion for different animals. 詳細
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Metyrapone 54-36-4 Autophagy Metabolism Others P450 Dehydrogenase CYPs Cushing's syndrome emotion behavior Sprague-Dawley rats depression Inhibitor Su 4885 Su4885 11β-hydroxylase Cytochrome P450 inhibit NSC-25265 water maze Su-4885 NSC 25265 NSC25265 aldosterone Endogenous Metabolite inhibitor