Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor(KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ,respectively)
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 10,000 | |||
5 mg | 在庫あり | ¥ 16,500 | |||
10 mg | 在庫あり | ¥ 28,000 | |||
25 mg | 在庫あり | ¥ 57,000 | |||
50 mg | 在庫あり | ¥ 85,000 | |||
100 mg | 在庫あり | ¥ 126,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 16,000 |
説明 | Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor(KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ,respectively) |
ターゲット&IC50 | PDGFRα:4 nM , FLK1:4 nM , FGFR1:2 nM , KDR:20 nM |
In vivo | Tyrosine kinase-IN-1 shows a reasonable PK profile (AUC(0–∞)=1.9, t1/2=4.6 h). It has a favorable oral bioavailability (F=63%) in rats |
分子量 | 445.53 |
分子式 | C26H28FN5O |
CAS No. | 705946-27-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 62.5 mg/mL (160.47 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Tyrosine kinase-IN-1 705946-27-6 Angiogenesis Tyrosine Kinase/Adaptors PDGFR FGFR FLT VEGFR Tyrosine kinase IN 1 Inhibitor Platelet-derived growth factor receptor Vascular endothelial growth factor receptor Fibroblast growth factor receptor inhibit Tyrosine kinaseIN1 inhibitor