Powder: -20°C for 3 years | In solvent: -80°C for 1 year
RGB-286638 free base is a novel CDK inhibitor with IC50s of 1 nM/2 nM/3 nM/4 nM/5 nM for cyclin T1-CDK9/cyclin B1-CDK1/cyclin E-CDK2/cyclin D1-CDK4/cyclin E-CDK3/p35-CDK5 respectively; less potent against cyclin H-CDK7 and cyclin D3-CDK6.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 16,000 | |||
2 mg | 在庫あり | ¥ 22,000 | |||
5 mg | 在庫あり | ¥ 34,000 | |||
10 mg | 在庫あり | ¥ 57,000 | |||
25 mg | 在庫あり | ¥ 112,000 | |||
50 mg | 在庫あり | ¥ 159,000 | |||
100 mg | お問い合わせ | ¥ 221,000 |
説明 | RGB-286638 free base is a novel CDK inhibitor with IC50s of 1 nM/2 nM/3 nM/4 nM/5 nM for cyclin T1-CDK9/cyclin B1-CDK1/cyclin E-CDK2/cyclin D1-CDK4/cyclin E-CDK3/p35-CDK5 respectively; less potent against cyclin H-CDK7 and cyclin D3-CDK6. |
ターゲット&IC50 | Cyclin T1-CDK9:1 nM, Cyclin E-CDK3:5 nM, Cyclin D1-CDK4:4 nM, Cyclin E-CDK2:3 nM, Cyclin B1-CDK1:2 nM |
分子量 | 545.63 |
分子式 | C29H35N7O4 |
CAS No. | 784210-88-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Slightly soluble
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
RGB-286638 free base 784210-88-4 Angiogenesis Cell Cycle/Checkpoint Chromatin/Epigenetic JAK/STAT signaling MAPK PI3K/Akt/mTOR signaling Stem Cells MEK JAK GSK-3 CDK inhibit MAP2K RGB286638 free base RGB286638 Glycogen synthase kinase-3 MAPKK Glycogen synthase kinase 3 RGB-286638 RGB 286638 free base Mitogen-activated protein kinase kinase Janus kinase Cyclin dependent kinase Inhibitor RGB 286638 inhibitor