Powder: -20°C for 3 years | In solvent: -80°C for 1 year
T-863(DGAT-1 inhibitor) is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells. IC50 value: Target: DGAT1 T863 (DGAT-3) causes weight loss, reduction in serum and liver triglycerides, and improved insulin sensitivity in obese mice.
説明 | T-863(DGAT-1 inhibitor) is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells. IC50 value: Target: DGAT1 T863 (DGAT-3) causes weight loss, reduction in serum and liver triglycerides, and improved insulin sensitivity in obese mice. |
別名 | DGAT-3, DGAT-1 inhibitor |
分子量 | 394.47 |
分子式 | C22H26N4O3 |
CAS No. | 701232-20-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (114.08 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
T863 701232-20-4 Metabolism Acyltransferase Transferase Diglyceride acyltransferase inhibit acyl-CoA:cholesterol acyltransferase T 863 Inhibitor DGAT-3 DGAT-1 inhibitor T-863 mono- acylglycerol acyltransferase DGAT3 DGAT 3 Diacylglycerol acyltransferase inhibitor