Powder: -20°C for 3 years | In solvent: -80°C for 1 year
UNC569 (UNC 569) is a selective inhibitor of URAT1, a transporter in the kidney that regulates uric acid excretion from the body. It is also a selective uric acid re-absorption inhibitor. UNC569 could normalize the amount of uric acid excreted by gout patients previously classified as under-excretors.
説明 | UNC569 (UNC 569) is a selective inhibitor of URAT1, a transporter in the kidney that regulates uric acid excretion from the body. It is also a selective uric acid re-absorption inhibitor. UNC569 could normalize the amount of uric acid excreted by gout patients previously classified as under-excretors. |
ターゲット&IC50 | Mer:2.9 nM(IC50), Mer:4.3 nM(Ki), Axl:37 nM(IC50) |
別名 | UNC 569 |
分子量 | 396.5 |
分子式 | C22H29FN6 |
CAS No. | 1350547-65-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL (75.66 mM), Sonication is recommended.
H2O: Insoluble
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
UNC569 1350547-65-7 Tyrosine Kinase/Adaptors TAM Receptor anti-oncogenic Inhibitor UNC-569 ATP-competitive ALL Tyro3 AKT ERK Mer inhibit pyrazolopyrimidine Axl UNC 569 inhibitor