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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T62822 | CT1-3 | ||
CT1-3 is a potent anti-cancer agent. CT1-3 regulates the JNK/Bcl-2/Bax/XIAP pathway, which induces mitochondria-mediated apoptosis. CT1-3 regulates the E-cadherin/Snail axis to inhibit epithelial mesenchymal transition (... | |||
T27093 | CT-1 | CT 1 | p53 |
CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis. | |||
T6435 | CCT129202 | Aurora Kinase | |
CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 0.042 μM, 0.198 μM and 0.227 μM, respectively. It is less potent to FGFR3, GSK3β, PDGFRβ, etc. | |||
T6303 | CCT128930 | Akt , PKA , S6 Kinase , Autophagy | |
CCT128930 is a potent, ATP-competitive and selective inhibitor of Akt2 with IC50 of 6 nM, 28-fold greater selectivity for Akt2 than the closely related PKA kinase. | |||
T6303L | CCT128930 hydrochloride | CCT128930 hydrochloride(885499-61-6 Free base) | Apoptosis , Akt , PKA , mTOR , Autophagy |
CCT128930 hydrochloride (CCT128930 hydrochloride) is a potent and selective inhibitor of AKT with IC50 of 6 nM. CCT128930 hydrochloride induces cell cycle arrest, DNA damage, and autophagy. CCT128930 hydrochloride has 28... | |||
T14903 | CCT129957 | Calcium Channel , Phospholipase | |
CCT129957 is a novel and potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of about 3 μM and a GC50 of 15 μM.CCT129957 exhibits anticancer activity and inhibits Ca2+ release in squamous cells. | |||
T4133 | CCT196969 | Raf , Src | |
CCT196969 is a novel orally available, pan-RAF inhibitor with anti-SRC activity. It also inhibits SRC, LCK, and the p38 MAPKs. | |||
T67727 | MCT1-IN-3 | Monocarboxylate transporter | |
MCT1-IN-3 is a monocarboxylate transporter 1 (MCT1) inhibitor. The solute carrier (SLC) monocarboxylate transporter 1 (MCT1; SLC16A1) represents a promising target for the treatment of cancer. MCT1-IN-3 (compound 24) sho... | |||
T79904 | PROTAC CDK9/CycT1 Degrader-2 | CDK | |
PROTAC CDK9/CycT1 Degrader-2 inhibits CDK9 with an IC50 of 45 nM [1]. | |||
T79187 | CT1113 | ||
CT1113, a potent inhibitor of both USP28 and USP25, effectively reduces MYC levels in vivo and demonstrates anti-tumor efficacy in a mouse pancreatic cancer CDX model [1]. | |||
T26221 | MCT1-IN-2 | SR13800,SR-13800,SR 13800 | |
SR13800 is a monocarboxylate transporter 1 (MCT1) inhibitor with cell-permeable. | |||
T70400 | CDK9/CycT1-IN-93 | ||
CDK9/CycT1-IN-93 is a highly specific, ATP-competitive inhibitor of CDK9/CycT1 with antiviral activity. |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-03917 | Cardiotrophin 1 Protein, Human, Recombinant | Human | HEK293 Cells |
Cardiotrophin 1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 21.2 kDa and the accession number is Q16619-1. | |||
TMPY-00398 | Cardiotrophin 1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Cardiotrophin 1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.5 kDa and the accession number is Q16619-1. | |||
TMPJ-00086 | CT-1 Protein, Human, Recombinant (His) | Human | E. coli |
Cardiotrophin-1, also known as CT-1 and CTF1, is a member of the IL-6 superfamily. It is a sreted cytokine that is expressed in heart, skeletal muscle, prostate and ovary, and to lower levels in lung, kidney, pancreas, t... | |||
TMPH-02151 | OXCT1 Protein, Human, Recombinant (His) | Human | E. coli |
Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of... | |||
TMPY-04316 | LECT1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
LECT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.1 kDa and the accession number is O75829-2. |