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検索結果

Search Results for " D-Serine "

15

阻害剤

5

天然化合物

19

リコンビナントタンパク質

1

同位体標識化合物

カタログ番号 製品名 別名 ターゲット
T66377 N-Cbz-D-serine Methyl Ester
N-Cbz-D-serine Methyl Ester is a useful organic compound for research related to life sciences. The catalog number is T66377 and the CAS number is 93204-36-5.
T13568L BCX 1470 hydrochloride BCX 1470 hydrochloride(217099-43-9 Free base),BCX1470 HCl Serine Protease , Complement System
BCX 1470 hydrochloride is a potent serine protease inhibitor with anti-inflammatory activity that inhibits the ester hydrolysis and haemolytic activity of factor D and C1s, and can be used to study oedema.
TP1920L1 Acein acetate RAAS
Acein acetate is a high-affinity angiotensin-converting enzyme (ACE) ligand (Kd = 2.79 nM). Concentrations up to 500 nM had no significant effect on ACE enzyme activity. Enhanced NMDA + D-serine-induced dopamine release ...
T37185 D-(-)-3-Phosphoglyceric acid disodium 3-Phospho-D-glyceric acid disodium Others
D-(-)-3-Phosphoglyceric acid disodium (3-Phospho-D-glyceric acid disodium) is an intermediate in several biological pathways, most notably glycolysis/gluconeogenesis and the biosynthesis of serine, glycine, and threonine...
T6904 Necrosulfonamide (E)-Necrosulfonamide MLK
(E)-Necrosulfonamide ((E)-Necrosulfonamide) is an inhibitor of necroptosis. Blocks mixed lineage kinase domain-like protein (MLKL), a critical substrate of receptor-interacting serine-threonine kinase 3 (RIP3) during nec...
T32853 Lombricine L-Lombricine Others
Lombricine, as a phosphodiester of 2-guanidinoethanol and D-serine in structure, is a phosphagen that is unique to earthworms.
T36396 D-Homoserine lactone Others
D-homoserine lactone is an enantiomer of L-homoserine lactone and an inhibitor of serine hydroxymethyltransferase (SHMT; Ki= 11 mM for the rabbit enzyme).1 1.Wang, E.A., Kallen, R., and Walsh, C.Mechanism-based inactivat...
T76170 D-Amino acid oxidase Others
D-Amino acid oxidase, an enzyme that metabolizes exogenous D-amino acids in animals for detoxification, also regulates the level of D-serine in the brain [1].
TP1920 Acein
Acein is a High affinity angiotensin-converting enzyme (ACE) ligand (Kd = 2.79 nM). Exhibits no significant effect on ACE enzymatic activity up to 500 nM concentration. Potentiates NMDA + D-serine-induced dopamine releas...
T78231 DAO-IN-1 Others
DAO-IN-1 is a potent D-amino acid oxidase (DAO) inhibitor, exhibiting an IC50 of 269 nM, which plays a key role in the metabolism of D-serine, a co-agonist of NMDA receptors [1].
T10939 D,L-Cystathionine dihydrochloride Others
D,L-Cystathionine dihydrochloride is an intermediate in the synthesis of cysteine, which acts from the isotype of cysteine-β-synthase (CBS) produced by leucine and serine. Derived from cysteine. DL-cysteine contains a cy...
T11269 FD-IN-1 Others
FD-IN-1 is a factor D (FD) inhibitor with an IC50 of 12 nM.FD-IN-1 also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5μM, respectively. Complement FD, a highly specific S1 serine protease, plays a...
T37056 D-erythro-MAPP Others
D-erythro-MAPP is a derivative of ceramide and an inhibitor of alkaline ceramidase (Ki = 2-13 μM; IC50 = 1-5 μM). It is selective for alkaline ceramidase over acid ceramidase (IC50 = >500 μM) as well as the serine/threon...
T84405 CRT0066101 hydrochloride Others
Protein kinase D (PKD), a serine/threonine protein kinase activated by diacylglycerol downstream of PKC signaling, has three human isoforms that modulate cell proliferation, survival, invasion, and protein transport. CRT...
T36643 PKI-166 hydrochloride Others
Potent EGFR-kinase inhibitor (IC50 = 0.7 nM). Displays >3000-fold selectivity against a panel of serine/threonine kinases. Reduces metastasis and angiogenesis in a mouse model of pancreatic cancer. Antihypertensive and o...
カタログ番号 製品名 別名 ターゲット
T8394 D-Serine (R)-Serine Endogenous Metabolite , NMDAR , iGluR
D-Serine ((R)-Serine) is an endogenous amino acid,is a potent co-agonist at the NMDA glutamate receptor.
T9143 D-Isoleucine (2R,3R)-2-Amino-3-methylpentanoic acid,(R)-Isoleucine Others
D-Isoleucine ((2R,3R)-2-Amino-3-methylpentanoic acid) is a selective activator of Asc-1 antiporter, which enhances long-term potentiation at the hippocampal CA1-CA3 via release of endogenous D-serine.
T8363 DL-Serine PKM
DL-Serine is a non-essential amino acid and a natural ligand and allosteric activator of pyruvate kinase M2.
T5085 Pyridoxal 5'-phosphate hydrate Codecarboxylase,Pyridoxal 5'-phosphate hydrate(1:x),PLP,Pyridoxal 5'-phosphate hydrate Others , Endogenous Metabolite
Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions, including mitochondrial cysteine desulfurase, cystathionine γ-synth...
T4825 D-(+)-Xylose D(+)-Xylose,(+)-Xylose,Wood sugar Endogenous Metabolite
D-(+)-Xylose (Wood sugar) is an aldopentose - a monosaccharide containing five carbon atoms and an aldehyde functional group. It has chemical formula C5H10O5 and is 40% as sweet as sucrose. Xylose is also found in mucopo...

天然物製品

D-Serine
T8394
Synonym: (R)-Serine
Target: Endogenous Metabolite, NMDAR, iGluR
D-Isoleucine
T9143
Synonym: (2R,3R)-2-Amino-3-methylpentanoic acid,(R)-Isoleucine
Target: Others
DL-Serine
T8363
Synonym:
Target: PKM
Pyridoxal 5'-phosphate hydrate
T5085
Synonym: Codecarboxylase,Pyridoxal 5'-phosphate hydrate(1:x),PLP,Pyridoxal 5'-phosphate hydrate
Target: Others, Endogenous Metabolite
D-(+)-Xylose
T4825
Synonym: D(+)-Xylose,(+)-Xylose,Wood sugar
Target: Endogenous Metabolite

Recombinant Proteins

Species：
Human (10)
Mouse (6)
Rat (1)
Rhesus (1)
Salmonella heidelberg (1)
Expression System：
E. coli (9)
HEK293 Cells (8)
Baculovirus Insect Cells (1)
P. pastoris (Yeast) (1)
Tag：
C-6xHis (5)
C-His (3)
N-6xHis (3)
N-His (3)
C-hFc (2)
N-6xHis-SUMO (2)
N-10xHis, C-Myc (1)
カタログ番号 製品名 Species Expression System
TMPH-03468 D-serine dehydratase Protein, Salmonella heidelberg, Recombinant (His & SUMO) Salmonella heidelberg E. coli
D-serine dehydratase Protein, Salmonella heidelberg, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 63.3 kDa and the accession number is B4TA53...
TMPH-02083 Serine racemase/SRR Protein, Human, Recombinant (His & SUMO) Human E. coli
Serine racemase/SRR Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-02528 SLC7A10 Protein, Mouse, Recombinant (His & SUMOstar) Mouse P. pastoris (Yeast)
Sodium-independent, high affinity transport of small neutral D- and L-amino acids and amino acid-related compounds. May play a role in the modulation of glutamatergic transmission through mobilization of D-serine at the ...
TMPY-02801 PHGDH Protein, Human, Recombinant (His) Human E. coli
PHGDH is a member of the D-isomer specific 2-hydroxyacid dehydrogenase family. This new family consists of D-isomer-stereospecific enzymes. The conserved residues in this family appear to be the residues involved in the ...
TMPJ-00459 Esterase D Protein, Human, Recombinant (His) Human E. coli
Human Esterase D is a cytoplasmic serine hydrolase that belongs to the esterase D family. Esterase D is involved in the detoxification of formaldehyde. Esterase D plays a part in a variety of substrates, including O-acet...
TMPH-02607 Complement factor B Protein, Mouse, Recombinant (His) Mouse E. coli
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convert...
TMPY-03391 ESD Protein, Human, Recombinant (His) Human E. coli
Esterase D, also known as ESD, is a serine hydrolase that belongs to the esterase D family. Esterase D is active toward numerous substrates including O-acetylated sialic acids, and it may be involved in the recycling of ...
TMPK-00151 Complement Factor D/CFD Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli sugge...
TMPH-02621 DAO Protein, Mouse, Recombinant (His) Mouse E. coli
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during agi...
TMPK-00671 Complement Factor D/CFD Protein, Rhesus macaque, Recombinant (His) Rhesus HEK293 Cells
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli sugge...
TMPK-00755 Complement Factor D/CFD Protein, Human, Recombinant (hFc) Human HEK293 Cells
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli sugge...
TMPJ-00832 Granzyme D/GZMD Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Granzyme D is a member of the granzyme family of the serine proteases which plays a role in the induction of apoptosis. T cells, lymphohematopoietic stromal cells, and granulated metrial gland cells express granzyme D, b...
TMPJ-00853 DAO Protein, Human, Recombinant (His) Human E. coli
D-Amino-Acid Oxidase (DAO) belongs to the DAMOX/DASOX family. DAO is a peroxisomal enzyme which founctions as a homodimer to oxidizes D-amino acids to the corresponding imino acids, producing ammonia and hydrogen peroxid...
TMPH-03276 DAO Protein, Rat, Recombinant (His & Myc) Rat E. coli
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during agi...
TMPJ-00149 Complement Factor D/CFD Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Complement factor D, also known as adipsin, is a member of the chymotrypsin family of serine proteases, which plays an essential role in host defense as the rate-limiting enzyme in the alternative pathway of complement a...
TMPY-03810 GALNT2 Protein, Human, Recombinant (His) Human HEK293 Cells
GALNT2, also known as GalNAc-T2, is a member of the GalNAc-transferases family. Members of this family transfer an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-link...
TMPJ-01320 BSSP-4 Protein, Human, Recombinant (His) Human HEK293 Cells
Brain-Specific Serine Protease 4 (BSSP-4) is a serine protease that preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. BSSP-4 is expressed abundantly in the epithelial c...
TMPJ-01223 GALNTL1 Protein, Human, Recombinant (His) Human HEK293 Cells
Putative polypeptide N-acetylgalactosaminyltransferase-like protein 1, also known as Polypeptide GalNAc transferase-like protein 1, Protein-UDP acetylgalactosaminyltransferase-like protein 1, UDP-GalNAc:polypeptide N-ace...
TMPY-04542 CDK2 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
CDK2 is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinas...
D-serine dehydratase Protein, Salmonella heidelberg, Recombinant (His & SUMO)
TMPH-03468
Species: Salmonella heidelberg
Expression System: E. coli
Serine racemase/SRR Protein, Human, Recombinant (His & SUMO)
TMPH-02083
Species: Human
Expression System: E. coli
SLC7A10 Protein, Mouse, Recombinant (His & SUMOstar)
TMPH-02528
Species: Mouse
Expression System: P. pastoris (Yeast)
PHGDH Protein, Human, Recombinant (His)
TMPY-02801
Species: Human
Expression System: E. coli
Esterase D Protein, Human, Recombinant (His)
TMPJ-00459
Species: Human
Expression System: E. coli
Complement factor B Protein, Mouse, Recombinant (His)
TMPH-02607
Species: Mouse
Expression System: E. coli
ESD Protein, Human, Recombinant (His)
TMPY-03391
Species: Human
Expression System: E. coli
Complement Factor D/CFD Protein, Mouse, Recombinant (hFc)
TMPK-00151
Species: Mouse
Expression System: HEK293 Cells
DAO Protein, Mouse, Recombinant (His)
TMPH-02621
Species: Mouse
Expression System: E. coli
Complement Factor D/CFD Protein, Rhesus macaque, Recombinant (His)
TMPK-00671
Species: Rhesus
Expression System: HEK293 Cells
Complement Factor D/CFD Protein, Human, Recombinant (hFc)
TMPK-00755
Species: Human
Expression System: HEK293 Cells
Granzyme D/GZMD Protein, Mouse, Recombinant (His)
TMPJ-00832
Species: Mouse
Expression System: HEK293 Cells
DAO Protein, Human, Recombinant (His)
TMPJ-00853
Species: Human
Expression System: E. coli
DAO Protein, Rat, Recombinant (His & Myc)
TMPH-03276
Species: Rat
Expression System: E. coli
Complement Factor D/CFD Protein, Mouse, Recombinant (His)
TMPJ-00149
Species: Mouse
Expression System: HEK293 Cells
GALNT2 Protein, Human, Recombinant (His)
TMPY-03810
Species: Human
Expression System: HEK293 Cells
BSSP-4 Protein, Human, Recombinant (His)
TMPJ-01320
Species: Human
Expression System: HEK293 Cells
GALNTL1 Protein, Human, Recombinant (His)
TMPJ-01223
Species: Human
Expression System: HEK293 Cells
CDK2 Protein, Human, Recombinant (His)
TMPY-04542
Species: Human
Expression System: Baculovirus Insect Cells

Isotope Products

カタログ番号 製品名 別名 ターゲット
T74145 Deutarserine
Deutarserine, a deuterium-modified analog of the endogenous compound D-serine (CTP 692), is utilized in schizophrenia research in adults [1].

Isotope Products

Deutarserine
T74145
Synonym:
Target:
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