|
T4369 |
SCH-23390 hydrochloride
|
R-(+)-SCH23390 hydrochloride |
Potassium Channel
,
Dopamine Receptor
,
5-HT Receptor
|
|
SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM). |
|
T12865 |
SCH-23390 maleate
|
R-(+)-SCH-23390 maleate |
Potassium Channel
,
Dopamine Receptor
,
5-HT Receptor
|
|
|
|
T6988 |
SKF 38393 hydrochloride
|
(±)-SKF-38393 hydrochloride,SKF-38393A,SKF38393 HCl |
Dopamine Receptor
|
|
SKF 38393 hydrochloride (SKF38393 HCl) is a selective dopamine D1/D5 receptor agonist. |
|
T60835 |
SKF83959
|
|
Dopamine Receptor
|
|
SKF83959, a benzazepine analog, is a selective and potent partial agonist of the dopamine D1 receptor with Ki values of 1.18, 7.56, 920, and 399 nM for rat D1, D5, D2, and D3 receptors, respectively.SKF83959 is a potent ... |
|
T16999 |
Tavapadon
|
PF-6649751,CVL-751 |
Dopamine Receptor
|
|
Tavapadon (CVL-751) is an orally active and highly selective dopamine D1/D5 receptor partial agonist. |
|
T22921 |
LE 300
|
|
Dopamine Receptor
,
5-HT Receptor
|
|
dopamine D1 receptor antagonist |
|
T23066 |
NGD 94-1
|
|
Dopamine Receptor
|
|
NGD 94-1 is a selective D4 receptor antagonist with an affinity of 3 nM for the D4 receptor and greater than 2 pM for the D1, D2, D3, and D5 receptors.NGD 94-1 can be used in the study of cognitive disorders and other ps... |
|
T31602 |
Ecopipam
|
Sch-39166,UNII-0X748O646K,Sch 39166 |
Dopamine Receptor
|
|
Ecopipam (UNII-0X748O646K) is a potent, selective and orally active antagonist of dopamine D1/D5 receptor, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam shows more than 40-flod selectivity over D2, D4, 5-HT, and ... |
|
T28167 |
NGB 2904
|
NGB2904 HCl,NGB-2904,NGB2904 |
Others
,
Dopamine Receptor
,
5-HT Receptor
|
|
NGB 2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively). NGB2904 potently antag... |
|
T5397 |
A-381393
|
|
Dopamine Receptor
|
|
A-381393 is a selective and brain penetrate dopamine D4 receptor antagonist (Kis: 1.9/1.5/1.6 nM for human dopamine D4.2/D4.4/D4.7 receptor). |
|
T7834 |
ABT-724
|
|
Dopamine Receptor
|
|
ABT-724 is an agonist of dopamine D4 receptor(EC50: 12.4 nM) |
|
T19342 |
Glycerol phenylbutyrate-D5
|
HPN-100-D5 |
Sigma receptor
|
|
Glycerol phenylbutyrate-D5 is a deuterium-labeled Glycerol phenylbutyrate. Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand (pKi: 8.02). |
|
T16893 |
SKF-82958
|
Chloro-AP,(±)-SKF 82958 |
Others
|
|
SKF 82958 is a D1/D5 receptor full agonist. |
|
T16892 |
SKF-82958 hydrobromide
|
(±)-SKF 82958 hydrobromide,Chloro-APB hydrobromide |
Others
|
|
SKF-82958 hydrobromide is a D1/D5 receptor full agonist. |
|
T13463L |
Dihydrexidine
|
DAR-0100 |
Dopamine Receptor
|
|
Dihydrexidine is a full efficacy D1-like dopamine receptor (D1/D5) agonist (IC50: 10 nM for D1 receptor). It also shows potent antiparkinsonian activity. |
|
T10440 |
Azilsartan-d5
|
TAK-536 D5 |
Others
|
|
Azilsartan (TAK-536) D5 is the deuterium-labeled Azilsartan. Azilsartan is a specific antagonist of the angiotensin II type 1 receptor. |
|
T10558 |
Blonanserin D5
|
AD-5423 D5 |
Others
|
|
Blonanserin D5 is a deuterium-labeled Blonanserin. Blonanserin (AD-5423) is a dopamine D2/5-HT2 receptor antagonist with an atypical antipsychotic effect. |
|
T0074L |
Chlorprothixene hydrochloride
|
NSC 78193,Minithixen,Truxal hydrochloride,NSC 56379,NSC 169899,Minithixen hydrochloride |
Dopamine Receptor
,
5-HT Receptor
,
Antibacterial
,
AChR
,
Histamine Receptor
|
|
Chlorprothixene hydrochloride (Truxal hydrochloride) brings strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors. Chlorprothixene hydrochloride s a typical an... |
|
T6647 |
Rotigotine-
|
Neupro,N-0923,N-0437,SPM 962 |
Dopamine Receptor
,
5-HT Receptor
,
Adrenergic Receptor
|
|
Rotigotine (N-0923) is a non-ergot dopamine receptor agonist used in the therapy of Parkinson disease and restless leg syndrome. Administered as a once-daily transdermal patch, Rotigotine has not been associated with ser... |
|
T13076 |
Tamoxifen-d5
|
ICI 47699-d5,(Z)-Tamoxifen-d5,trans-Tamoxifen-d5 |
HSP
|
|
Tamoxifen-d5 is a deuterium labeled Tamoxifen. Tamoxifen is a selective modulator of estrogen receptor (SERM). Tamoxifen is a potent activator of Hsp90 and enhances the Hsp90 molecular chaperone ATPase activity. |
|
TMIH-0486 |
Ramelteon-d5
|
|
|
|
Ramelteon-d5 is a deuterated compound of Ramelteon. Ramelteon has a CAS number of 196597-26-9. Ramelteon is a Melatonin Receptor Agonist. The mechanism of action of ramelteon is as a Melatonin Receptor Agonist. |
|
T12973 |
Solifenacin D5 hydrochloride
|
|
Others
|
|
Solifenacin D5 hydrochloride is a deuterium labeled Solifenacin hydrochloride. Solifenacin hydrochloride is an antagonist of muscarinic receptor(pKis of 7.6, 6.9 and 8.0 for M1, M2 and M3 receptors, respectively). |
|
T67921 |
Retinoic acid-d5
|
all-trans-Retinoic acid-d5,Isotretinoin-d5,Vitamin A acid-d5,Accutane-d5,ATRA-d5 |
Retinoid Receptor
|
|
Retinoic acid-d5 (Vitamin A acid-d5) is the deuterium-labeled form of Retinoic acid. Retinoic acid is a natural RAR receptor agonist with an IC50 of 14 nM for RARα/β/γ and a Kd of 17 nM for PPARβ/δ. Retinoic acid, a meta... |
|
T73823 |
DETQ
|
|
|
|
DETQ, a selective, allosteric, and orally active potentiator of the dopamine D1 receptor (Dopamine Receptor), enhances cAMP production in HEK293 cells expressing the human D1 receptor, achieving an EC50 of 5.8 nM and a K... |
|
TMIH-0235 |
Finerenone-d5
|
|
|
|
Finerenone-d5 is a deuterated compound of Finerenone. Finerenone has a CAS number of 1050477-31-0. Finerenone is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist... |
|
T70035 |
Tasimelteon-d5
|
|
|
|
Tasimelteon-d5 is intended for use as an internal standard for the quantification of tasimelteon by GC- or LC-MS. Tasimelteon is a melatonin (MT) receptor agonist. It selectively binds MT1 and MT2 receptors over a panel ... |
|
T21446 |
Rotigotine Hydrochloride
|
Rotigotine (Hydrochloride),N 0923,N-0924,Rotigotine HCl,N-0923 |
Dopamine Receptor
,
5-HT Receptor
,
Adrenergic Receptor
|
|
Rotigotine Hydrochloride (N-0924), a dopamine receptor agonist prefering for D3 receptors over D1 and D2, has effective activity of anti-Parkinsonian. Racemic rotigotine hydrochloride is about 50 times as potent as quinp... |
|
T70313 |
Indoxyl Sulfate-d5 potassium salt
|
|
|
|
Indoxyl sulfate-d5 is intended for use as an internal standard for the quantification of indoxyl sulfate by GC- or LC-MS. Indoxyl sulfate is a uremic toxin and a metabolite of tryptophan. It is formed via sulfation of in... |
|
T23364 |
SKF 83959 hydrobromide
|
|
Others
|
|
SKF 83959 hydrobromide is a Dopamine D1-like receptor partial agonist. |
|
T23381 |
Spiperone hydrochloride
|
|
Others
|
|
5-HT2A serotonin and selective D2-like dopamine receptor antagonist |
|
T12676 |
(Rac)-Rotigotine hydrochloride
|
|
Dopamine Receptor
|
|
(Rac)-Rotigotine hydrochloride is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial the 5-HT1A receptor agonist. |
|
T22858 |
Iloperidone hydrochloride
|
|
Others
|
|
Iloperidone hydrochloride is a D(2)/5-HT(2) receptor antagonist. It is also an atypical antipsychotic for the treatment of schizophrenia symptoms. |
