|
T3967 |
Exendin-4
|
Exenatide,Exenatide Acetate |
Glucagon Receptor
|
|
Exendin-4 (Exenatide) is a glucagon-like peptide-1 receptor (GLP-1) agonist (IC50: 3.22 nM). Exenatide is a 39 amino acid peptide. Compared to GLP-1, exenatide has a longer half-life of 2.4 hours. |
|
T6533 |
Hexestrol
|
Bibenzyl,Hexanoestrol,meso-Hexestrol,Hexestrofen |
Estrogen Receptor/ERR
,
Estrogen/progestogen Receptor
|
|
Hexestrol (Hexanoestrol) binds to ERα and ERβ with EC50 of 0.07 nM and 0.175 nM, respectively. |
|
T5024 |
Cefotiam Hexetil Hydrochloride
|
|
Antibacterial
,
Antibiotic
|
|
Cefotiam Hexetil Hydrochloride is a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. |
|
T2400 |
Candesartan Cilexetil
|
TCV-116 |
Apoptosis
,
RAAS
|
|
Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist (IC50: 0.26 nM). After hydrolysis of candesartan cilexetil to candesartan during gastrointestinal absorption, candesartan selectively competes with... |
|
T8355 |
Exenatide
|
Exendin-4,Extendin-4 |
Glucagon Receptor
|
|
Exenatide (Extendin-4) is a glucagon-like protein-1 (GLP-1) receptor agonist. |
|
T6226 |
Pemetrexed disodium hemipenta hydrate
|
Pemetrexed Disodium Hydrate,LY-231514 Disodium Hydrate,Pemetrexed sodium hydrate |
Apoptosis
,
DHFR
,
DNA/RNA Synthesis
,
Antifolate
,
Autophagy
|
|
Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT. The Ki of Pemetrexed Disodium Hydrate for TS, DHFR and GARFT is 1.3 nM, 7.2 nM and 6... |
|
T6632 |
Raltitrexed
|
ZD1694,D1694,ICI-D1694,Tomudex |
Nucleoside Antimetabolite/Analog
,
DNA/RNA Synthesis
|
|
Raltitrexed (D1694)(IC50 of 9 nM), a thymidylate synthase inhibitor, is used for the inhibition of L1210 cell growth. |
|
T0328 |
Hexetidine
|
NSC-17764 |
Antibacterial
,
Antifungal
|
|
Hexetidine (NSC-17764) is a bactericidal and fungicidal antiseptic. It is used as a 0.1% mouthwash for local infections and oral hygiene. |
|
T0189 |
Pemetrexed
|
Pemetrexed acid,LY231514,LY-231514 Disodium Hydrate |
DHFR
,
DNA/RNA Synthesis
,
Antifolate
,
Autophagy
|
|
Pemetrexed (LY-231514 Disodium Hydrate), a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate synthase (TS). |
|
T8748 |
Exendin-4 acetate
|
|
Glucagon Receptor
|
|
Exendin-4 acetate is a 39 amino acid peptide.Exendin-4 acetate is a long-acting GLP-1 receptor agonist(IC50 = 3.22 nM). |
|
T2627 |
Nolatrexed dihydrochloride
|
Thymitaq,AG 337 |
DNA/RNA Synthesis
|
|
Nolatrexed dihydrochloride (Thymitaq) is the dihydrochloride salt of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity. Nolatrexed occupies the folate binding site of thymidyla... |
|
T0189L |
Pemetrexed disodium
|
LY-231514,LY231514 disodium,Pemetrexed |
Apoptosis
,
DHFR
,
DNA/RNA Synthesis
,
Antifolate
,
Autophagy
|
|
Pemetrexed disodium (LY-231514) is a parenterally administered folate antagonist and antineoplastic agent, used in the treatment of non-small cell lung cancer and malignant mesothelioma. Pemetrexed disodium therapy has b... |
|
T15198 |
Edasalonexent
|
CAT-1004 |
NF-κB
|
|
Edasalonexent (CAT-1004) is an orally available NF-κB inhibitor for the improvement of Duchenne muscular dystrophy. |
|
T0016 |
Mexenone
|
Mesenone,Uvistat,Benzophenone-10 |
Others
|
|
Mexenone (Uvistat) is a benzophenone-derived sun protection. |
|
T21591 |
1H-1-ethyl Candesartan Cilexetil
|
|
Others
|
|
1H-1-ethyl Candesartan Cilexetil is a process-related impurity in the bulk synthesis of candesartan cilexetil, which is a potent, long-acting and selective angiotensin II type 1 receptor (AT1) antagonist. |
|
TP1389 |
Exendin-3/4 (64-86)
|
|
Others
|
|
Exendin-3/4 (64-86) is a polypeptide. |
|
T4228 |
Nolatrexed
|
|
DNA/RNA Synthesis
|
|
Nolatrexed is a thymidylate synthase inhibitor with potential anticancer activity. |
|
T27154 |
Dexelvucitabine
|
D-D-4FC,DPC-817,RVT,beta-D-D-4FC,DFC |
Reverse Transcriptase
|
|
Dexelvucitabine (RVT), a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection. |
|
T25316 |
Dexecadotril
|
Retorphan |
|
|
Dexecadotril is a powerful and selective neprilysin inhibitor. It behaves as a prodrug of the enantiomer of thiorphan. |
|
T31735 |
Exeporfinium chloride
|
XF 73,XF73,XF-73 |
|
|
Exeporfinium chloride(XF-73) is an antimicrobial agent that can weaken bacterial cell walls. |
|
T76291 |
Des His1, Glu8 Exendin-4
|
|
|
|
Des His1, Glu8 Exendin-4 is a potent antagonist of the glucagon-like peptide-1 receptor (GLP-1-R), enhancing glucose homeostasis through the dual regulation of insulin secretion and glucose production. This compound is e... |
|
TP1366 |
Exendin-3/4 (59-86)
|
|
|
|
Exendin-3/4 (59-86) is a Exendin-4 peptide derivative. |
|
T39384 |
Exendin (5-39)
|
|
|
|
Exendin (5-39) is a powerful antagonist of the glucagon-like peptide 1 (GLP-1) receptor with the ability to ameliorate memory impairment in rats treated with β-amyloid protein. |
|
T76587 |
(Asp28)-Exenatide
|
|
|
|
(Asp28)-Exenatide is a degradation product of exenatide . (Asp28)-Exenatide can be used as a GLP-1R agonist [1] . |
|
T71931 |
Clencyclohexerol
|
|
|
|
Clencyclohexerol is an analog of clenbuterol. β-Adrenoceptor agonists, including clenbuterol, modulate protein synthesis and degradation and have therapeutic potential in muscle wasting disorders. β-adrenoceptor agonists... |
|
T36002 |
4-hydroxy Hexenal
|
4-HHE,4-hydroxy Hexenal |
|
|
4-hydroxy Hexenal is a lipid peroxidation product derived from oxidized ω-3 fatty acids such as DHA. [1][2] |
|
T69825 |
Dexetimide HCl
|
|
|
|
Dexetimide HCl is a muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Benzetimide is the (-)-enantimorph of dexetimide. |
|
T15104 |
Dexetimide
|
(+)-Benzetimide,Dexbenzetimide,(S)-(+)-Dexetimide |
Others
|
|
Dexetimide ((+)-Benzetimide) is a high-affinity antagonist of the muscarinic receptor. It is a persistent anticholinergic agent and can be used to treat neuroleptic-induced parkinsonism. |
|
T74111 |
N-Methyl pemetrexed
|
|
|
|
N-Methyl pemetrexed, an impurity found in Pemetrexed, serves as an antifolate cytotoxic agent utilized in cancer research [1]. |
|
T12674 |
(Rac)-Plevitrexed
|
(Rac)-ZD 9331,(Rac)-BGC9331 |
Others
|
|
(Rac)-Plevitrexed is a racemate of Plevitrexed. Plevitrexed is an orally active and potent inhibitor of thymidylate synthase (TS). |
|
T70583 |
Pemetrexed Diethyl Ester
|
|
|
|
Pemetrexed Diethyl Ester is a protected intermediate in the synthesis of Pemetrexed, a multi-targeted anti-folate that inhibits thymidylate synthase as well as other folate dependent enzymes. |
|
T69044 |
Hexestrol dipropionate
|
|
|
|
Hexestrol dipropionate is a synthetic ER agonist, microtubule polymerization inhibitor, and potential carcinogen. It induces mitotic arrest, aneuploidy, and DNA adduct formation. |
|
T66032 |
Pemetrexed disodium heptahydrate
|
|
|
|
Pemetrexed disodium is a guanine-derived antineoplastic agent that functions as a nucleic acid synthesis inhibitor through its binding to, and inhibition of, thymidylate synthase. |
|
T16737 |
Revexepride
|
|
Others
|
|
Revexepride is a highly selective agonist of the 5-HT4 receptor and a potential inducer of CYP3A4 enzyme. Revexepride is used for the treatment of gastroesophageal reflux disease. |
|
T25929 |
Pemetrexed tromethamine
|
Pemetrexed ditromethamine dihydrate |
|
|
Pemetrexed tromethamine is a chemotherapy drug used for pleural mesothelioma and non-small cell lung cancer. |
|
T81624 |
Obexelimab
|
XmAb5871 |
|
|
Obexelimab (XmAb5871) is a humanized Fc-engineered anti-CD19 antibody with enhanced affinity for FcγRIIb, utilized in the study of autoimmune diseases [1]. |
|
T77163 |
Pexelizumab
|
|
|
|
Pexelizumab (h5G1.1-SC), a humanized scFv monoclonal antibody, targets the C5 complement component, thereby inhibiting apoptosis and leukocyte infiltration. It is utilized in researching cerebral ischemia-reperfusion (IR... |
|
TP1394 |
{Val1}-Exendin-3/4
|
|
|
|
{Val1}- exendin-3/4 is the first n-terminal 1-28 residue of exendin-4 peptide. |
|
TP1461 |
SDV-Exendin-3/4
|
|
|
|
SDV-Exendin-3/4 is a 32-amino acid peptide. |
|
TP1768 |
Exendin-3
|
|
|
|
Exendin-3 is a biologically active peptides isolated from venoms of the Gila monster lizards, Heloderma horridurn . Exendin-3 is a pancreatic secretagogue, which is a member of the glucagon family. It is found in the ve... |
|
T76648 |
Acetyl-Exenatide
|
|
|
|
Acetyl-Exenatide, an acetylated derivative of Exenatide, mirrors insulin's functionality and is utilized in type 2 diabetes research. It promotes Th17 differentiation, inhibits Tregs differentiation, and downregulates PI... |
|
TP1392 |
Exendin derivative 1
|
|
|
|
Exendin derivative 1 is a 39 amino acid peptide. |
|
T35169 |
Xenyhexenic acid
|
SCR157,CV 57733,CV-57733,CV57733,CV 57533 |
|
|
Xenyhexenic acid is a biochemical. |
|
T34936 |
Tridihexethyl chloride
|
Propethonum,Pathilon,Tridihexethyl |
|
|
Tridihexethyl is an anticholinergic, antimuscarinic, and antispasmolytic drug, which can be used to treat acquired nystagmus or peptic ulcer disease. |
|
T31136 |
Cyclohexene, decafluoro-
|
Decafluorocyclohexene,Perfluorocyclohexene |
|
|
Cyclohexene, decafluoro- is also known as Perfluorocyclohexene. Perfluorocycloalkene (PFCA) is a general class of fluorocarbon compounds comprising many commercially available perfluorocyclo-olefins including hexafluoroc... |
|
T12635L |
Plevitrexed
|
BGC9331,ZD 9331 |
Others
|
|
Plevitrexed is taken up via the α-folate receptor as well as the reduced folate carrier. Plevitrexed is an orally active and effective thymidylate synthase (TS) inhibitor (Ki: 0.44 nM). Plevitrexed is used for gastric ca... |
|
T12635 |
(R)-Plevitrexed
|
(R)-ZD 9331,(R)-BGC9331 |
Others
|
|
(R)-Plevitrexed is a less active enantiomer of Plevitrexed. Plevitrexed is an orally active and potent inhibitor of thymidylate synthase (TS). |
|
T124181 |
3-hydroxy-4-E-Hexenoic acid
|
|
|
|
3-hydroxy-4-E-Hexenoic acid is a useful organic compound for research related to life sciences. The catalog number is T124181 and the CAS number is 81357-32-6. |
|
T76290 |
Exendin-4 (3-39)
|
|
|
|
Exendin-4 (3-39) is a truncated peptide variant of Exendin-4, missing the initial two amino acids, and serves as a potent agonist for the Glucagon-like peptide-1 receptor (GLP-1r). This compound, along with Exendin-4, is... |
|
T29315 |
2,2'-Dimethyl hexestrol
|
|
|
|
2,2'-Dimethyl hexestrol is a bioactive chemical. |
