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Search Results for " Guanidine "

ターゲット

32

阻害剤

6

天然化合物

カタログ番号 製品名 別名 ターゲット
T50058 1-(cyclohexylmethyl)guanidine hydroiodide Others
1-(cyclohexylmethyl)guanidine hydroiodide is a guanidine derivative that has been used as a reagent in the synthesis of a variety of compounds, including peptides, peptoids, and other bioactive molecules, and as a cataly...
T50030 1-(2,4-difluorophenyl)guanidine hydrochloride Others
1-(2,4-difluorophenyl)guanidine hydrochloride is a compound that is a potent and selective inhibitor of the voltage-gated sodium channel Nav1.7, a key player in pain signaling. It is therefore able to reduce pain signali...
T50092 1,1'-(Heptane-1,7-diyl)diguanidine dihydrochloride 1-(7-carbamimidamidoheptyl)guanidine dihydrochloride Others
1,1'-(Heptane-1,7-diyl)diguanidine dihydrochloride is a potent and selective small molecule inhibitor of glycogen synthase kinase-3 (GSK-3). It is used in studies of stem cell differentiation, tumors and neurodegenerativ...
T50091 1,1'-(Octane-1,8-diyl)diguanidine dihydrochloride 1-(8-carbamimidamidooctyl)guanidine dihydrochloride Others
1,1'-(Octane-1,8-diyl)diguanidine dihydrochloride is a synthetic opioid peptide derived from the natural opioid peptide enkephalin. It is a potent agonist of the mu-opioid receptor (MOR) with a Ki of 0.14 nM, making it o...
T66809 Guanidine thiocyanate
Guanidine thiocyanate is a useful organic compound for research related to life sciences. The catalog number is T66809 and the CAS number is 593-84-0.
T24833 ZINC69391 ZINC-69391,ZINC 69391,N'-(4,6-dimethylpyrimidin-2-yl)-N-[2-(trifluoromethyl)phenyl]guanidine,CysHHC10 acetate(1408311-03-4 free base) Apoptosis , Rho
ZINC69391 (CysHHC10 acetate(1408311-03-4 free base)) is a selective inhibitor of Rac1 with antiproliferative and antimetastatic effects. ZINC69391 interferes with the interaction of Rac1 with Dock180, reduces Rac1-GTP le...
TNU1455 N,N’-bis-Cbz-N’’-(2-hydroxyethyl)-guanidine
N,N'-bis-Cbz-N''-(2-hydroxyethyl)-guanidine is a Fine Chemical.
T32017 M-Heptamethyleniminomethylbenzylguanidine sulfate Guanidine, (3-(hexahydro-1(2H)-azocinylmethyl)benzyl)-, sulfate
Guanidine, (3-(hexahydro-1(2H)-azocinylmethyl)benzyl)-, sulfate is a bioactive chemical.
T50109 Guanethidine
Guanethidine sulphate, synthesized in 1959, is thought to lowing blood pressure by interfering with the metabolism of chemical transmitter substances in post-ganglionic sympathetic nerve fibres.
T0510 Sulfaguanidine Sulfaguine,Guanicil Antibacterial , Antibiotic , Autophagy
Sulfaguanidine (Guanicil), a sulfonamide, is served as an anti-infective agent.
T21703 4-Chlorophenylguanidine hydrochloride Others
4-Chlorophenylguanidine hydrochloride is a potent inhibitor of urokinase selectivity.
T20253 N,N'-Diphenylguanidine NSC 3272,NSC3272,NSC-3272 Others
N,N'-Diphenylguanidine (NSC-3272) is an agent of biochemical.
T5969 Ditolylguanidine DTG,Di-o-tolylguanidine,1,3-Di-o-tolylguanidine Sigma receptor
Ditolylguanidine (Di-o-tolylguanidine) is an agonist of sigma receptor (σ1/σ2 receptor).
T0358 Aminoguanidine hydrochloride Imino semicarbazide,Pimagedine hydrochloride,CP-12009-18 tartrate,Hydrazinecarboximidamide,Guanyl hydrazine,Pimagedine NOS , NO Synthase
Aminoguanidine hydrochloride (Hydrazinecarboximidamide) is a diamine oxidase and NO synthase inhibitor, used in the treatment of diabetic nephropathy.
T78229 Aminoguanidine hemisulfate Reactive Oxygen Species
Aminoguanidine hemisulfate, an inhibitor of nitric oxide synthases (NOS) and reactive oxygen species (ROS), effectively suppresses ANE-induced ROS production in vitro and is utilized in cancer research [1].
T60530 Mercaptoethylguanidine (MEG) (dihydrobromide)
Mercaptoethylguanidine (MEG) dihydrobromide is a selective inducible nitric oxide synthase inhibitor and peroxynitrite scavenger with potential for inflammatory bowel diseases research.
T67064 1,1-Dimethylguanidine Sulfate(2:1)
1,1-Dimethylguanidine Sulfate(2:1) is a useful organic compound for research related to life sciences. The catalog number is T67064 and the CAS number is 598-65-2.
T20246 1,2,3-Triphenylguanidine NSC4051,NSC-4051,NSC 4051
1,2,3-Triphenylguanidine is an agent of biochemical.
T67763 PK095 ATPase
PK095 is a proprietary compound in the guanidine - based F1F0-ATPase inhibitor family.
T12478L Pinacidil S 1230,P 1134,S-1230,P-1134,P1134 Potassium Channel
Pinacidil (P 1134) is a guanidine that opens potassium channels and directly dilates peripheral blood vessels in small arteries, lowering blood pressure and peripheral resistance and producing fluid retention.
T62396 KB-5492 free base Sigma receptor
KB-5492 free base is an orally available, selective antiulcer agent that inhibits sigma receptors and inhibits [3H]1,3-di(2-tolyl)guanidine (DTG) binding to sigma receptors and can be used in studies of gastric lesions a...
T9462 2-Amino-6-cyclopropylamino-9H-purine Others
2-Amino-6-cyclopropylamino-9H-purine,the key intermediate of abacavir was synthesized from ethyl cyanoacetate by nitrosation,cyclization with guanidine hydrochloride in the presence of EtONa and reduction to give 2,4,5-t...
T1320 Disopyramide Triombrin,Hypaque sodium,amidotrizoate sodium Potassium Channel , Sodium Channel , AChR
Disopyramide (Triombrin) is a class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the h...
T4206 E6446 TLR
E6446 inhibits Toll-like receptor (TLR)7 and 9 signaling. E6446 works in a variety of human and mouse cell types and inhibits DNA-TLR9 interaction in vitro. When administered to mice, this compound suppress responses to ...
T111959 IFB-088 acetate
IFB-088 acetate, a benzyl guanidine derivative, is used to treat diseases and cancers associated with the PPP1R15A pathway and associated with protein misfolding stress, Examples include tau disease, synaptic riboprotein...
T33610 NC-174 CPDpmGA,CP Dpm GA,CP-Dpm-GA,CP-DpmGA,CPDpm-GA
NC-174 is a trisubstituted guanidine high potency synthetic sweetener.
T20697 Robenidine Chimcoccide,Khimcoccid
Robenidine, an anticoccidial guanidine, is used as an additive in rabbit fodder.
T23662 Aganodine Aganodin
Aganodine is a guanidine that activates presynaptic imidazoline receptors. Aganodine inhibits the presynaptic release of norepinephrine through its agonism at imidazoline receptors.
T37100 1,5,7-Triazabicyclo[4.4.0]dec-5-ene
1,5,7-Triazabicyclo[4.4.0]dec-5-ene is a bicyclic guanidine base that can be used as a catalyst for a variety of base-mediated organic transformations, including Michael additions, Wittig reactions, Henry reactions, and ...
T25739 Linogliride McN-3935,McN3935,McN 3935,Linogliridum,Linoglirida
Linogliride is a guanidine-based inhibitor of insulin secretion and a structural analog of pirogliride with hypoglycemic activity. It blocks ATP-sensitive potassium channels in the pancreatic beta cell membrane, thereby ...
T68714 Iobenguane I 131
Iobenguane I 131 is a guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. MIB...
T25739L Linogliride fumarate McN 3935,McN-3935,McN3935
Linogliride fumarate is the fumarate salt of Linogliride. Linogliride is a guanidine-based inhibitor of insulin secretion and a structural analog of pirogliride with hypoglycemic activity. It blocks ATP-sensitive potassi...

Compounds

1-(cyclohexylmethyl)guanidine hydroiodide
T50058
Synonym:
Target: Others
1-(2,4-difluorophenyl)guanidine hydrochloride
T50030
Synonym:
Target: Others
1,1'-(Heptane-1,7-diyl)diguanidine dihydrochloride
T50092
Synonym: 1-(7-carbamimidamidoheptyl)guanidine dihydrochloride
Target: Others
1,1'-(Octane-1,8-diyl)diguanidine dihydrochloride
T50091
Synonym: 1-(8-carbamimidamidooctyl)guanidine dihydrochloride
Target: Others
Guanidine thiocyanate
T66809
Synonym:
Target:
ZINC69391
T24833
Synonym: ZINC-69391,ZINC 69391,N'-(4,6-dimethylpyrimidin-2-yl)-N-[2-(trifluoromethyl)phenyl]guanidine,CysHHC10 acetate(1408311-03-4 free base)
Target: Apoptosis, Rho
N,N’-bis-Cbz-N’’-(2-hydroxyethyl)-guanidine
TNU1455
Synonym:
Target:
m-Heptamethyleniminomethylbenzylguanidine sulfate
T32017
Synonym: Guanidine, (3-(hexahydro-1(2H)-azocinylmethyl)benzyl)-, sulfate
Target:
Guanethidine
T50109
Synonym:
Target:
Sulfaguanidine
T0510
Synonym: Sulfaguine,Guanicil
Target: Antibacterial, Antibiotic, Autophagy
4-Chlorophenylguanidine hydrochloride
T21703
Synonym:
Target: Others
N,N'-Diphenylguanidine
T20253
Synonym: NSC 3272,NSC3272,NSC-3272
Target: Others
Ditolylguanidine
T5969
Synonym: DTG,Di-o-tolylguanidine,1,3-Di-o-tolylguanidine
Target: Sigma receptor
Aminoguanidine hydrochloride
T0358
Synonym: Imino semicarbazide,Pimagedine hydrochloride,CP-12009-18 tartrate,Hydrazinecarboximidamide,Guanyl hydrazine,Pimagedine
Target: NOS, NO Synthase
Aminoguanidine hemisulfate
T78229
Synonym:
Target: Reactive Oxygen Species
Mercaptoethylguanidine (MEG) (dihydrobromide)
T60530
Synonym:
Target:
1,1-Dimethylguanidine Sulfate(2:1)
T67064
Synonym:
Target:
1,2,3-Triphenylguanidine
T20246
Synonym: NSC4051,NSC-4051,NSC 4051
Target:
PK095
T67763
Synonym:
Target: ATPase
Pinacidil
T12478L
Synonym: S 1230,P 1134,S-1230,P-1134,P1134
Target: Potassium Channel
KB-5492 free base
T62396
Synonym:
Target: Sigma receptor
2-Amino-6-cyclopropylamino-9H-purine
T9462
Synonym:
Target: Others
Disopyramide
T1320
Synonym: Triombrin,Hypaque sodium,amidotrizoate sodium
Target: Potassium Channel, Sodium Channel, AChR
E6446
T4206
Synonym:
Target: TLR
IFB-088 acetate
T111959
Synonym:
Target:
NC-174
T33610
Synonym: CPDpmGA,CP Dpm GA,CP-Dpm-GA,CP-DpmGA,CPDpm-GA
Target:
Robenidine
T20697
Synonym: Chimcoccide,Khimcoccid
Target:
Aganodine
T23662
Synonym: Aganodin
Target:
1,5,7-Triazabicyclo[4.4.0]dec-5-ene
T37100
Synonym:
Target:
Linogliride
T25739
Synonym: McN-3935,McN3935,McN 3935,Linogliridum,Linoglirida
Target:
Iobenguane I 131
T68714
Synonym:
Target:
Linogliride fumarate
T25739L
Synonym: McN 3935,McN-3935,McN3935
Target:
カタログ番号 製品名 別名 ターゲット
T0415 Guanidine hydrochloride Guanidine HCl,Aminoformamidine HCl,Aminoformamidine Hydrochloride,Guanidinium chloride Others , Arginase , DNA/RNA Synthesis , Endogenous Metabolite , Autophagy
Guanidine hydrochloride (Aminoformamidine Hydrochloride) is a strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also u...
T4904 1-Methylguanidine hydrochloride Others , Endogenous Metabolite
Methylguanidine (MG) is a guanidine compound deriving from protein catabolism. It is also a product of putrefaction. Methylguanidine is a suspected uraemic toxin that accumulates in renal failure, however it also exhibit...
T20390 Cyanoguanidine NSC2031,Dicyandiamide,NSC 2031,NSC-2031
Cyanoguanidine is an agent of antimicrobial.
T4753 Imidazoleacetic acid hydrochloride I4AA,(4-Imidazolyl)acetic acid hydrochloride,4-Imidazoleacetic acid hydrochloride Endogenous Metabolite , Antibiotic
Imidazoleacetic acid hydrochloride (I4AA) is an imidazole derivative with potential antituberculosis properties. It also used in the preparation of acyl guanidine inhibitors of β-secretase.
T4238 Glycocyamine 2-Guanidinoacetic acid,Guanidoacetic acid Others , Endogenous Metabolite
Glycocyamine (2-Guanidinoacetic acid), a precursor of creatine, is a replacement of dietary arginine and could support overall energy homeostasis of the bird. Glycocyamine is an important marker for renal failure, kidney...
T35532 Galegine hydrochloride
Galegine hydrochloride, a guanidine derivative derived from G. officinalis, plays a role in inducing weight loss in mice and has contributed to the development of biguanides, including metformin and phenformin. This comp...