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Search Results for " HuR "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T20206	Oxymethurea	CSI Paste,Carbamol,Caurite,Dimethylolurea	Others
	Oxymethurea (CSI Paste) is a modified urea and can be used as in agricultural fields as a slow-release fertilizer.		Others
T32094	Holothurin B
	Holothurin B, as a part of a group of toxins, is originally isolated from the sea cucumber Actinopyga agassizi.
T32093	Holothurin A
	Holothurin A is a triterpene glycoside.
T124549	Ashurbin

T34863	Thurfyl Salicylate	Tetrahydrofurfuryl salicylate
	Thurfyl Salicylate (tetrahydrofurfuryl Salicylate) is a redness preparation used for the treatment of musculoskeletal, joint, periarticular, and soft tissue pain.
T32095	Holothurinogenin	Nobilisidenol A
	Holothurinogenin, as a lanosterol derivative, has toxic to nerve tissue.
T36493	CMLD-2		Apoptosis , HuR
	CMLD-2 is an inhibitor of HuR-ARE interaction (Ki: 350 nM) that competitively binds HuR protein and disrupts its interaction with adenine element-rich (ARE) mRNA targets.CMLD-2 induces apoptosis and exhibits antitumor ef...		Apoptosis , HuR
T73286	SRI-42127		HuR
	SRI-42127 is a novel small molecule inhibitor of the RNA regulatory factor HuR, which inhibits tumor growth, attenuates glial activation in a lipopolysaccharide-induced neuroinflammation model, and reduces neuropathic pa...		HuR
T28228	Okicenone
	Okicenone is an antibiotic, interferring with HuR RNA binding, HuR trafficking, T-cell activation and cytokine expression.
T72920	Azaphilone-9	AZA-9
	Azaphilone-9 (AZA-9) functions as an inhibitor of the HuR-ARE RNA interaction, with an inhibition constant (IC50) of 1.2 μM, by targeting the RNA-binding protein Hu antigen R (HuR). As HuR-RNA interactions play a critica...
T62398	KH-3
	KH-3 is a potent inhibitor (IC50: 0.35 μM) of the RNA-binding protein Hu antigen R (HuR) and exhibits anti-proliferative effects. KH-3 interferes with HuR-FOXQ1 Mrna interactions, inhibits breast cancer cell invasion, an...
T71116	MPT0B098
	MPT0B098 is a potent microtubule inhibitor through binding to the colchicine-binding site of tubulin. MPT0B098 is active against the growth of various human cancer cells, including chemoresistant cells with IC50 values r...
T35993	Epitalon (acetate)
	Epitalon is a synthetic tetrapeptide with anti-aging properties.1,2,3,4 Dietary administration of epitalon (0.00001% w/w) reduces levels of lipid peroxidation products in aged D. melanogaster tissue homogenates.1 Epitalo...

Compounds

Oxymethurea

T20206

Synonym: CSI Paste,Carbamol,Caurite,Dimethylolurea

Synonym: Tetrahydrofurfuryl salicylate

Target:

Holothurinogenin

T32095

Synonym: Nobilisidenol A

Target: Apoptosis, HuR

カタログ番号	製品名	別名	ターゲット
T3010	Xanthurenic Acid	8-Hydroxykynurenic acid,4,8-Dihydroxyquinaldic acid,xanthurenate	Apoptosis , Endogenous Metabolite , GluR
	Xanthurenic Acid (8-Hydroxykynurenic acid), a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine, activates mGlu2/3 Metabotropic glutamate receptors (mGlu2 and mGlu3).		Apoptosis , Endogenous Metabolite , GluR
TN1509	Clematomandshurica saponin C	Clematiunicinoside E	Others
	Clematiunicinoside E is a natural product from Clematis uncinata.		Others
TN6587	Clemomandshuricoside B
	Clemomandshuricoside B is a natural product for research related to life sciences. The catalog number is TN6587 and the CAS number is 905294-48-6.
TN1510	Clematomandshurica saponin B		COX
	Clematomandshurica saponin B shows significant inhibitory activity on cyclooxygenase-2 (IC50 = 2.58 microM).		COX
TN1574	Dhurrin		Others
	Dhurrin is a natural product		Others
TN6277	Phyllanthurinolactone
	Phyllanthurinolactone is a natural product for research related to life sciences. The catalog number is TN6277 and the CAS number is 168180-12-9.
T13636	Dahurinol		Others
	Dasalinol is a natural compound isolated from the cedar (Cimicifuga acerina).		Others
TN3653	Cimidahurinine		BCL , ROS
	Cimidahurinine can attenuate Doxorubicin (DOX)-induced cardiotoxicity in a dose-dependent manner with EC50 values of 45.79 uM; it protects against cardiotoxicity by decreasing reactive oxygen species (ROS) accumulation a...		BCL , ROS

天然物製品

Xanthurenic Acid

T3010

Synonym: 8-Hydroxykynurenic acid,4,8-Dihydroxyquinaldic acid,xanthurenate

Target: Apoptosis, Endogenous Metabolite, GluR

Clematomandshurica saponin C

TN1509

Synonym: Clematiunicinoside E

Target: Others

Clemomandshuricoside B

TN6587

Synonym:

Target:

Clematomandshurica saponin B

Phyllanthurinolactone

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-00183	Cry1Ac Protein, Bacillus thuringiensis subsp., Recombinant (GST)	Bacillus thuringiensis subsp. kurstaki	E. coli
	Promotes colloidosmotic lysis by binding to the midgut epithelial cells of many lepidopteran larvae. Cry1Ac Protein, Bacillus thuringiensis subsp., Recombinant (GST) is expressed in E. coli expression system with N-GST t...
TMPH-00177	Cry1Bb Protein, Bacillus thuringiensis, Recombinant (His & Myc)	Bacillus thuringiensis	E. coli
	Promotes colloidosmotic lysis by binding to the midgut epithelial cells of many lepidopteran larvae. Cry1Bb Protein, Bacillus thuringiensis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis...
TMPH-00182	Cry2Aa Protein, Bacillus thuringiensis subsp., Recombinant (His & Myc)	Bacillus thuringiensis subsp. kurstaki	E. coli
	Promotes colloidosmotic lysis by binding to the midgut epithelial cells of both dipteran (Aedes aegypti) and lepidopteran (Manduca sexta) larvae. Cry2Aa Protein, Bacillus thuringiensis subsp., Recombinant (His & Myc) is ...
TMPH-00179	Cry1Ab Protein, Bacillus thuringiensis subsp., Recombinant (His)	Bacillus thuringiensis subsp. kurstaki	P. pastoris (Yeast)
	Promotes colloidosmotic lysis by binding to the midgut epithelial cells of many lepidopteran larvae. Cry1Ab Protein, Bacillus thuringiensis subsp., Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted ...
TMPH-00180	Cry1Ab Protein, Bacillus thuringiensis subsp., Recombinant (His & SUMO)	Bacillus thuringiensis subsp. kurstaki	E. coli
	Promotes colloidosmotic lysis by binding to the midgut epithelial cells of many lepidopteran larvae. Cry1Ab Protein, Bacillus thuringiensis subsp., Recombinant (His & SUMO) is expressed in E. coli expression system with ...
TMPH-00178	AiiA Protein, Bacillus thuringiensis subsp., Recombinant (His & Myc)	Bacillus thuringiensis subsp. kurstaki	E. coli
	Catalyzes hydrolysis of N-hexanoyl-(S)-homoserine lactone, but not the R-enantiomer. Hydrolyzes short- and long-chain N-acyl homoserine lactones with or without 3-oxo substitution at C3, has maximum activity on C10-AHL. ...
TMPY-04517	Influenza A H3N2 (A/Christchurch/4/1985) Hemagglutinin/HA1 Protein (His)	H3N2	HEK293 Cells
	Influenza A H3N2 (A/Christchurch/4/1985) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.8 kDa and the accession number is O40888.
TMPH-00186	Cry3Aa Protein, Bacillus thuringiensis subsp., Recombinant (His)	Bacillus thuringiensis subsp. tenebrionis	E. coli
	Promotes colloidosmotic lysis by binding to the midgut epithelial cells of Coleoptera. Cry3Aa Protein, Bacillus thuringiensis subsp., Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The pred...
TMPH-00184	Cry1Fb Protein, Bacillus thuringiensis subsp., Recombinant (His)	Bacillus thuringiensis subsp. morrisoni	E. coli
	Promotes colloidosmotic lysis by binding to the midgut epithelial cells of insects. Cry1Fb Protein, Bacillus thuringiensis subsp., Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predict...
TMPH-00181	Cry1Ia Protein, Bacillus thuringiensis subsp., Recombinant (His & KSI)	Bacillus thuringiensis subsp. Kurstaki	E. coli
	Promotes colloidosmotic lysis by binding to the midgut epithelial cells of certain coleopteran and lepidopteran species. Active on Plutella xylostella and Bombyx mori. Cry1Ia Protein, Bacillus thuringiensis subsp., Recom...
TMPH-00185	Cry2Ab Protein, Bacillus thuringiensis subsp., Recombinant (His)	Bacillus thuringiensis subsp. kurstaki	E. coli
	Promotes colloidosmotic lysis by binding to the midgut epithelial cells of lepidopteran (Manduca sexta) larvae. Cry2Ab Protein, Bacillus thuringiensis subsp., Recombinant (His) is expressed in E. coli expression system w...