|
T11997 |
MELK-IN-1
|
Nintedanib Impurity L,MELK inhibitor 17 |
MELK
|
|
MELK-IN-1 (MELK inhibitor 17) is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK),(IC50:3nm;Ki:0.39 nM). |
|
T11996 |
MELK-8a hydrochloride
|
|
MELK
|
|
|
|
T1759 |
OTSSP167
|
MELK inhibitor,OTS167 |
MELK
|
|
OTSSP167 (OTS167) is an orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity. |
|
T35342 |
MELK-8a Dihydrochloride
|
|
MELK
|
|
MELK-8a Dihydrochloride is a useful organic compound for research related to life sciences and the catalog number is T35342. |
|
T62417 |
MELK-8a
|
|
|
|
MELK-8a (NVS-MELK8a) is a potent and selective inhibitor of maternal embryonic leucine elongation kinase (MELK) (IC50: 2 nM). 0.42 μM). Among them, MELK plays an important role in regulating mitosis in cancer cells. |
|
T11725 |
JNJ-47117096 hydrochloride
|
MELK-T1 hydrochloride |
Others
|
|
|
|
T21559 |
OTSSP167 hydrochloride
|
|
MELK
|
|
OTSSP167 hydrochloride is a highly potent inhibitor of MELK(IC50 : 0.41 nM). |
|
T4327 |
Prexasertib dihydrochloride
|
LY2606368 (dihydrochloride),Prexasertib HCl,LY2606368 |
Apoptosis
,
Chk
,
S6 Kinase
|
|
Prexasertib dihydrochloride (LY2606368) is an ATP-competitive CHK1 inhibitor (Ki: 0.9 nmol/L). in the cell-free assay, its IC50 values are 8 nM and 9 nM for CHK2 and RSK, respectively. |
|
T4310 |
Prexasertib
|
LY2606368 |
Apoptosis
,
Chk
|
|
Prexasertib (LY2606368) is an inhibitor of checkpoint kinase 1 (chk1) with potential antineoplastic activity. |
|
T24152 |
HTH-01-091
|
HTH-01091,HTH01-091,HTH 01-091,HTH 01091 |
Serine/threonin kinase
,
Pim
,
MELK
,
DYRK
,
CDK
,
RIP kinase
|
|
HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM).HTH-01-091 inhibits PIM1/2/3, RIPK2, DYRK3, smMLCK and CLK2. HTH-01-091 can be used to study breast cancer. |
|
T71197 |
JW-7-25-1
|
|
|
|
JW-7-25-1 is a potent multi-target inhibitor, acting on MELK, PIK3CA, mTOR, GSK3A and CDK7. |
|
T79582 |
Antitumor agent-116
|
|
MELK
|
|
Antitumor Agent-116 (Compound 6C) is an anti-tumor agent that exhibits anti-proliferative properties and induces apoptosis. It demonstrates binding affinity for the MELK receptor [1]. |
|
T73867 |
HTH-01-091 TFA
|
|
|
|
HTH-01-091 TFA, a potent and selective inhibitor of maternal embryonic leucine zipper kinase (MELK), exhibits an IC50 of 10.5 nM. Besides its primary target, it also inhibits PIM1/2/3, RIPK2, DYRK3, smMLCK, and CLK2, pos... |
|
T82385 |
FMF-06-098-1
|
|
PROTACs
|
|
FMF-06-098-1 is a multitargeted depressant capable of promoting the degradation of a wide array of kinases, including AAK1, ABL2, AURKA, AURKB, BUB1B, CDC7, CDK1, CDK12, CDK13, CDK2, CDK4, CDK6, CDK7, CDK9, CHEK1, CSNK1D... |
|
T12237 |
NMS-P715
|
|
Casein Kinase
,
Kinesin
,
MELK
,
MAPK
|
|
NMS-P715 is a selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM). |
|
T16142 |
MRT199665
|
|
Others
|
|
MRT199665 is an effective and ATP-competitive, selective MARK/SIK/AMPK inhibitor (IC50s of 2/2/3/2 nM, 10/10 nM, and 110/12/43 nM for MARK1/MARK2/MARK3/MARK14, AMPKα1/AMPKα2, and SIK1/SIK2/SIK3, respectively). MRT199665 ... |
