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155

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T83680	Azurin (50-77) (P. aeruginosa) TFA	Azurin p28,p28
	Azurin (50-77) is a peptide fragment derived from the copper-containing bacterial protein azurin, present in P. aeruginosa. It exhibits properties that regulate the cell cycle, inhibit cancer proliferation, and manage an...
T4017	Relebactam	MK-7655	Antibacterial
	Relebactam (MK-7655) is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases.		Antibacterial
T0396	Pipemidic acid	Acido pipemidico	Antibacterial , Antibiotic
	Pipemidic acid (Acido pipemidico), a new antibacterial agent, inhibits the activity of Pseudomonas aeruginosa.		Antibacterial , Antibiotic
T19794	Temafloxacin	Omniflox	Antibiotic
	Temafloxacin (Omniflox) is an antibiotic and antimycobacterial agent. It used to treat lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections.		Antibiotic
T0827	Cefsulodin sodium	Cefsulodine sodium,Sulcephalosporin	Antibacterial , Antibiotic
	Cefsulodin sodium (Sulcephalosporin) hydrate is a β lactam antibiotic.		Antibacterial , Antibiotic
T4201	Avibactam sodium	AVE-1330A,NXL-104	Antibacterial , Antibiotic
	Avibactam sodium (NXL-104) is a reversible β-lactamase inhibitor (IC50: 8/80/38 nM, for TEM-1/P99/KPC-2 β-lactamases).		Antibacterial , Antibiotic
T6179	Moxalactam sodium salt	Latamoxef sodium,6059 S,Moxalactam Disodium,LY-127935,Antibiotic 6059S,Shiomarin,FestamoxinLy	Antibacterial , Antibiotic
	Moxalactam sodium salt (LY-127935) is an antibiotic compound more effective against Escherichia coli and Pseudomonas aeruginosathan cephalosporins.		Antibacterial , Antibiotic
T1293	Gatifloxacin	BMS 206584-01,PD 135432,CG5501,BMS-206584,AM-1155	Topoisomerase , Antibacterial , Antibiotic
	Gatifloxacin (CG5501) is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial enzymes DNA gyrase and topoisomerase IV.		Topoisomerase , Antibacterial , Antibiotic
T20711	Hemipyocyanine	528-71-2	Amylase
	Hemipyocyanine (528-71-2) is the virulence factor of Gram-negative, aerobic rod bacterium Pseudomonas aeruginosa. Hemipyocyanine is an α-Amylase inhibitor.		Amylase
T38173	Propargylcholine	Propargylcholine (bromide)	Antibacterial
	Propargylcholine (Propargylcholine (bromide)) is an alkyne-modified choline analog and inhibits choline catabolism at the level of Dgc enzyme-catalyzed dimethylglycine demethylation in Pseudomonas aeruginosa.		Antibacterial
T67912	PA3552-IN-1
	PA3552-IN-1 is an antibiotic adjuvant that can reduce the expression of PA3552 and restore the sensitivity of MDR Pseudomonas aeruginosa DK2 strain to Polymyxin B.
T8533	ML318		Others , Antibiotic
	ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site). ML318 inhibits P. aeruginosa (PAO1) with IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of...		Others , Antibiotic
T9119	SU0268		Others
	SU0268 is a potent and specific 8-Oxoguanine DNA glycosylase 1 (OGG1) inhibitor. SU0268 regulates inflammatory responses during Pseudomonas aeruginosa infection.		Others
T7495	Hexa-D-arginine		Others
	Hexa-D-arginine is an inhibitor of furin,blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo.		Others
T65309	S-Methyl methanesulfonothioate		Antibacterial
	S-Methyl methanesulfonothioate is a biological raw material with cytotoxicity and potential antimicrobial activity for the study of Pseudomonas aeruginosa infections.		Antibacterial
T38137	3,5-Dimethylbenzaldehyde		Endogenous Metabolite , Antifungal
	3,5-Dimethylbenzaldehyde has broad-spectrum antimicrobial activity, inhibiting Bacillus subtilis, Pseudomonas albicans, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus pneumoniae.		Endogenous Metabolite , Antifungal
TP1663L	CysHHC10 acetate	CysHHC10 acetate(1408311-03-4 free base)	Antibacterial
	CysHHC10 acetate shows antibacterial activities against both Gram-positive and Gram-negative bacteria with MIC of 10.1, 20.2, 2.5, and 1.3 mM for E. coli, P. aeruginosa, S. aureus, and S. epidermidis, respectively.		Antibacterial
TP1050L	Murepavadin acetate(944252-63-5 free base)		Antibacterial , Antibiotic
	Murepavadin acetate is a potent and specific antibiotic for the treatment of bacterial infections cused by Pseudomonas aeruginosa. Murepavadin acetate targets the lipopolysaccharide transport portin D.		Antibacterial , Antibiotic
T77686	1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone		Antifungal
	1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone has broad-spectrum antifungal activity with inhibitory effects on Candida albicans, Aspergillus niger, Pseudomonas aeruginosa and Staphylococcus aureus.		Antifungal
T4998L	Cefpodoxime (free acid)		Others
	Cefpodoxime (free acid) is an oral, third-generation cephalosporin antibiotic. It is active against most Gram-positive and Gram-negative organisms, except Pseudomonas aeruginosa, Enterococcus, and Bacteroides fragilis.		Others
T22269	Benzyldodecyldimethylammonium Chloride Dihydrate		Antibacterial
	Benzyldodecyldimethylammonium chloride dihydrate can be used as an insecticide reagent. It can target drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, multidrug-resistant Pseudomonas aerugino...		Antibacterial
T23858	WCK-5153	WCK 5153,WCK5153	Antibacterial
	WCK-5153 is an enhancer of β-Lactamase and an inhibitor of PBP2 with antimicrobial activities against Pseudomonas aeruginosa. WCK-5153 can be used in studies about the treatment of serious infections caused by highly dru...		Antibacterial
T78226	Methyl 2-amino-5-bromobenzoate	Methyl 5-Bromoanthranilate	HCV Protease , Antifungal
	Methyl 2-amino-5-bromobenzoate (Methyl 5-Bromoanthranilate) is a hepatitis C virus NS5b RNA polymerase inhibitor with antimicrobial activity that inhibits Pseudomonas aeruginosa infections and is involved in the producti...		HCV Protease , Antifungal
T7858	Ceftezole sodium	Celoslin,Falomesin,Alomen	Anti-infection , Antibacterial , Antibiotic , Glucosidase
	Ceftezole sodium (Falomesin) is a broad-spectrum cephalosporin antibiotic active gram-negative and gram-positive bacteria except for Proteus vulgaris, Pseudomonas aeruginosa, and Serratia marcescens. It has the inhibitio...		Anti-infection , Antibacterial , Antibiotic , Glucosidase
T60247	Diethylamine NONOate diethylammonium salt	NOC-18 Diethylamine,DEA NONOate diethylamine	Antibiotic
	Diethylamine NONOate diethylammonium salt (DEA NONOate diethylamine) is a nitric oxide donor with antibacterial activity, a dispersant for preformed biofilms of Pseudomonas aeruginosa and inhibits the growth of E. coli. ...		Antibiotic
T124492	Imipenem	N-Formimidoyl thienamycin,MK0787	Antifungal
	Imipenem (MK0787) is a thienomycin derivative that belongs to the class of antibiotics with antibacterial activity and partial inhibition against gram-positive and gram-negative bacteria. Imipenem can be used to study ca...		Antifungal
T41275	PF-04753299		Others
	PF-04753299 is a potent and selective inhibitor of UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase (LpxC), demonstrating bactericidal effects against gonococcal isolates. It exhibits inhibitory activity aga...		Others
T13789	N-dodecanoyl-L-Homoserine lactone	C12-HSL	Others
	N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule, a microbial communication mechanism modulated by acyl homoserine lactone (AHL) molecules impacts biofilm formation in bioreactors.		Others
T35449	α-(difluoromethyl)-DL-Arginine	DFMA,RMI 71897,α-(difluoromethyl)-DL-Arginine	Others
	α-(difluoromethyl)-DL-Arginine (RMI 71897) is an enzyma-activated, irreversible inhibitor of arginine decarboxylase for E. coli (Ki = 800 μM), Pseudomonas aeruginosa, and Klebsiella pneumoniae. At 0.01 mM, it has been sh...		Others
T13395L	Zidebactam	WCK-5107	Antibacterial
	Zidebactam (WCK-5107) is an effective β-lactamase inhibitor. Zidebactam also is a penicillin-binding protein2 inhibitor (IC50: 0.26 μg/mL).		Antibacterial
T14043	4-(tert-Butyl)-benzhydroxamic Acid		Others
	4-(tert-Butyl)-benzhydroxamic Acid is a PqsR antagonist with IC50s of 12.5 μM and 23.6 μM for E. coli and P. aeruginosa, respectively, and it reduces the production of the virulence factor pyocyanin in P. aeruginosa with...		Others
T14492	BAL-30072		Others
	BAL30072 shows MIC90 values of 4 μg/mL for MDR Acinetobacter spp. and 8 μg/mL for MDR P. aeruginosa, respectively[1][2]. BAL-30072, a siderophore sulfactam, is a monocyclic beta-lactam antibiotic, with activity against m...		Others
T25810	Micropeptin 478A	Micropeptin 478 A,Micropeptin 478-A
	Micropeptin 478A is a plasmin inhibitor from the Cyanobacterium Microcystis aeruginosa.
T33857	PA Autoinducer	3O-C12 autoinducer,PA-Autoinducer
	PA Autoinducer is a Pseudomonas aeruginosa autoinducer.
T25811	Micropeptin 478B
	Micropeptin 478B is a plasmin inhibitor from the Cyanobacterium Microcystis aeruginosa.
T25280	Cyanopeptolin 954	Cyanopeptolin-954,Cyanopeptolin954
	Cyanopeptolin 954 is a chlorine-containing Microcystis aeruginosa NIVA Cya 43 chymotrypsin Inhibitor.
T25136	Aztreonam lysine	Corus 1020,Corus1020,Corus-1020,Aztreonam lysinate
	Aztreonam lysine is an inhaled anti-pseudomonal treatment for people who have pulmonary Pseudomonas aeruginosa infection with cystic fibrosis (CF).
T62773	OX11
	OX11 is a selective inhibitor of S. pneumoniae, P. aeruginosa and E. coli bacteria.
T13788	N-Butanoyl-DL-homoserine lactone	(Rac)-C4-HSL	Others
	N-Butanoyl-DL-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa.		Others
T39983	SPR206 acetate
	SPR206 acetate is a polymyxin analog that exhibits antibiotic activity against Gram-negative pathogens, including multidrug-resistant (MDR) variants. By interacting with the outer membrane of the bacterium, SPR206 acetat...
T39296	DS86760016
	DS86760016 is a highly effective inhibitor of leucyl-tRNA synthetase (LeuRS), demonstrating potent activity against multidrug-resistant (MDR) Gram-negative bacteria including Escherichia coli, Klebsiella pneumoniae, and ...
T80285	KAMP-19
	KAMP-19 is a keratin-derived antimicrobial peptide with activity against P. aeruginosa. [1]
T15142	Vebufloxacin	OPC7241,Flumenique,DM8966	Antibacterial
	Vebufloxacin (OPC-7251) shows potent antibacterial activity against gram-positive and -negative bacteria, including Staphylococcus aureus and Pseudomonas aeruginosa. It has potent activity characteristically against Prop...		Antibacterial
T77184	Rivabazumab
	Rivabazumab is a recombinant antibody against Pseudomonas aeruginosa pcrV [1] .
T78537	Cefetamet pivoxyl	Ro 15-8075 free base	Antibiotic
	Cefetamet pivoxyl, a cephalosporin antibiotic, effectively inhibits 355 enteropathogens, including Gram-negative bacteria (ausgenommen Pseudomonas aeruginosa) and Legionella pneumophila [1].		Antibiotic
T61368	FPI-1602
	FPI-1602 is a β-lactamase inhibitor with strong antimicrobial activity against Pseudomonas aeruginosa, Escherichia coli, and Enterobacter species [1].
T77029	Gremubamab
	Gremubamab (MEDI3902), a humanized IgG1 kappa anti-PcrV/Psl monoclonal antibody, specifically targets and binds to the Pseudomonas aeruginosa PcrV protein and Psl exopolysaccharide. It shows promise for the study of Pseu...
T37912	Furanone C-30
	Synthetic furanone bacterial quorum sensing inhibitor. Inhibits virulence factor expression in Pseudomonas aeruginosa and increases bacterial susceptibility to antibiotics in vitro. Also inhibits bacterial quorum sensing...
T79004	ATP synthase inhibitor 2 TFA
	ATP Synthase Inhibitor 2 (Compound 22) TFA is a potent inhibitor of Pseudomonas aeruginosa ATP synthase with an IC50 value of 10 μg/mL. It effectively halts ATP synthesis in Pseudomonas aeruginosa at a concentration of 1...
T64422	Murepavadin
	Murepavadin is a highly potent, specific, macrocycle Pseudomonas antibiotic for the treatment of bacterial infections caused by Pseudomonas aeruginosa..

Compounds

Azurin (50-77) (P. aeruginosa) TFA

T83680

Synonym: Azurin p28,p28

Target: Antibacterial

Pipemidic acid

T0396

Synonym: Acido pipemidico

Target: Antibacterial, Antibiotic

Synonym: Cefsulodine sodium,Sulcephalosporin

Target: Antibacterial, Antibiotic

Avibactam sodium

T4201

Synonym: AVE-1330A,NXL-104

Target: Antibacterial, Antibiotic

Moxalactam sodium salt

T6179

Synonym: Latamoxef sodium,6059 S,Moxalactam Disodium,LY-127935,Antibiotic 6059S,Shiomarin,FestamoxinLy

Target: Antibacterial, Antibiotic

Gatifloxacin

T1293

Synonym: BMS 206584-01,PD 135432,CG5501,BMS-206584,AM-1155

Target: Topoisomerase, Antibacterial, Antibiotic

Synonym: Propargylcholine (bromide)

Target: Antibacterial

Target: Others, Antibiotic

S-Methyl methanesulfonothioate

T65309

Synonym:

Target: Antibacterial

3,5-Dimethylbenzaldehyde

T38137

Synonym:

Target: Endogenous Metabolite, Antifungal

CysHHC10 acetate

TP1663L

Synonym: CysHHC10 acetate(1408311-03-4 free base)

Target: Antibacterial

Murepavadin acetate(944252-63-5 free base)

TP1050L

Synonym:

Target: Antibacterial, Antibiotic

1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone

T77686

Synonym:

Target: Antifungal

Cefpodoxime (free acid)

T4998L

Synonym:

Target: Others

Benzyldodecyldimethylammonium Chloride Dihydrate

T22269

Synonym:

Target: Antibacterial

WCK-5153

T23858

Synonym: WCK 5153,WCK5153

Target: Antibacterial

Methyl 2-amino-5-bromobenzoate

T78226

Synonym: Methyl 5-Bromoanthranilate

Target: HCV Protease, Antifungal

Ceftezole sodium

T7858

Synonym: Celoslin,Falomesin,Alomen

Target: Anti-infection, Antibacterial, Antibiotic, Glucosidase

Diethylamine NONOate diethylammonium salt

T60247

Synonym: NOC-18 Diethylamine,DEA NONOate diethylamine

Target: Antibiotic

Imipenem

T124492

Synonym: N-Formimidoyl thienamycin,MK0787

N-dodecanoyl-L-Homoserine lactone

T13789

Synonym: C12-HSL

Target: Others

α-(difluoromethyl)-DL-Arginine

T35449

Synonym: DFMA,RMI 71897,α-(difluoromethyl)-DL-Arginine

Target: Antibacterial

4-(tert-Butyl)-benzhydroxamic Acid

Synonym: Micropeptin 478 A,Micropeptin 478-A

Target:

PA Autoinducer

T33857

Synonym: 3O-C12 autoinducer,PA-Autoinducer

Synonym: Cyanopeptolin-954,Cyanopeptolin954

Target:

Aztreonam lysine

T25136

Synonym: Corus 1020,Corus1020,Corus-1020,Aztreonam lysinate

N-Butanoyl-DL-homoserine lactone

T13788

Synonym: (Rac)-C4-HSL

Synonym: OPC7241,Flumenique,DM8966

Target: Antibacterial

Synonym: Ro 15-8075 free base

ATP synthase inhibitor 2 TFA

カタログ番号	製品名	別名	ターゲット
T2904	Sclareolide	Norambreinolide	Others , Antibacterial
	Sclareolide (Norambreinolide) is a sesquiterpene lactone natural product derived from various plant sources including Salvia yosgadensis, Salvia sclarea, and cigar tobacco. It is a close analog of Sclareol, a plant antif...		Others , Antibacterial
T5779	MOSLOFLAVONE		IL Receptor , Virus Protease , TNF , Antibacterial
	MOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and 7.8 μM, respectively.		IL Receptor , Virus Protease , TNF , Antibacterial
TN1544	D-Menthol	Menthol,(+)-MENTHOL	Calcium Channel , 5-HT Receptor , AChR
	D-Menthol ((+)-MENTHOL) is a common compound in pharmaceutical and commercial products and a popular additive to cigarettes, it attenuates α±7 mediated Ca 2+ transients in the cell body and neurite, suggests that menthol...		Calcium Channel , 5-HT Receptor , AChR
TN1877	Lonicerin		Apoptosis , Antibacterial
	Lonicerin has antioxidant, anti-arthritic and antifungal activities, it can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection.		Apoptosis , Antibacterial
T5780	HYPOCRELLIN B		Apoptosis , Parasite , Antifungal
	HYPOCRELLIN B are photosensitive pigments isolated from Hypocrella bambusae Sacc. Hypocrellin B causes DNA strand breakage, induces apoptosis in ovarian cancer cells, and inhibits proliferation of Staphylococcus by incre...		Apoptosis , Parasite , Antifungal
T1505	Imipenem monohydrate	N-Formimidoyl thienamycin monohydrate,Imipenem	Antibacterial , Antibiotic
	Imipenem monohydrate (Imipenem) is a broad-spectrum, semi-synthetic beta-lactam carbapenem derived from thienamycin, produced by Streptomyces cattleya.		Antibacterial , Antibiotic
T8384	Gatifloxacin hydrochloride	AM-1155 (hydrochloride),BMS-206584 (hydrochloride),PD135432 (hydrochloride)	Topoisomerase , Antibacterial , Antibiotic
	Gatifloxacin hydrochloride (AM-1155 hydrochloride) is an antibiotic of the fourth-generation fluoroquinolone family, which can inhibit the bacterial enzyme DNA rotase and topoisomerase IV.		Topoisomerase , Antibacterial , Antibiotic
TQ0251	(Z)-2-decenoic acid	(Z)-dec-2-enoic acid,cis-2-Decenoic acid,cis-dec-2-enoic acid	Others
	(Z)-2-decenoic acid (cis-dec-2-enoic acid) is an unsaturated short-chain fatty acid secreted by Pseudomonas aeruginosa. It can induce a dispersion response in biofilms formed by gram-negative and gram-positive bacteria. ...		Others
T8185	(+)-Viroallosecurinine	Viroallosecurinine	Antibacterial
	(+)-Viroallosecurinine (Viroallosecurinine) is a natural alkaloid with antibacterial activity. It exhibits a MIC of 0.48 μg/mL for Ps. Aeruginosa and Staph. aureus.		Antibacterial
T38373	2-heptyl-3-hydroxy-4(1H)-Quinolone	2-heptyl-3-hydroxy-4(1H)-Quinolone,PQS,Pseudomonas Quinolone Signal	Others
	2-heptyl-3-hydroxy-4(1H)-Quinolone (Pseudomonas Quinolone Signal) is a quorum-sensing signalling molecule produced by Pseudomonas aeruginosa in response to increased cell density. It increases the expression of the lasB ...		Others
T4816	6-Hydroxynicotinic acid	6-Hydroxypyridine-3-carboxylic acid,2-Hydroxy-5-pyridinecarboxylic acid	Others , Endogenous Metabolite
	6-Hydroxynicotinic acid (6-Hydroxypyridine-3-carboxylic acid) is exploited in the use of NMR spectroscopy or gas chromatography--mass spectrometry for the diagnosis of Pseudomonas aeruginosa in urinary tract infection. A...		Others , Endogenous Metabolite
T8433	HQNO		Mitochondrial Metabolism
	HQNO is a natural product isolated from P. aeruginosa,and is a potent inhibitor of electron transport chain(Kd of 64 nM for complex III). It also is a potent mitochondrial NDH-2 inhibitorin many species.		Mitochondrial Metabolism
T5707	3-O-Methylgalangin	3-Methylgalangin,GALANGIN-3-METHYLETHER	Antibacterial
	3-O-Methylgalangin (GALANGIN-3-METHYLETHER) has antibacterial activity, it has inhibitory effects on Pseudomonas aeruginosa. GALANGIN-3-METHYLETHER has hypolipidemic activity, the action is due to the inhibition of pancr...		Antibacterial
TN2111	Prunin	Naringenin 7-0-glucoside	Phosphatase , Anti-infection , Virus Protease
	Prunin (Naringenin 7-0-glucoside) possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-resistant HepG2 cells; it also can...		Phosphatase , Anti-infection , Virus Protease
T8066	Sulbenicillin disodium	Sulbenicillin Sodium	Antibacterial , Antibiotic
	Sulbenicillin disodium (Sulbenicillin Sodium) is a penicillin antibiotic,is a Penicillin antibiotic with antibacterial activity		Antibacterial , Antibiotic
T37341	N-Acetyltyramine		Antibacterial
	N-acetyltyramine is a metabolite of the biogenic amine tyramine . It enhances cytotoxicity of doxorubicin in resistant P388 murine leukemia cells with an IC50 value of 0.13 μg/ml compared with an IC50 value of 0.48 μg/ml...		Antibacterial
TN3861	Dihydropinosylvin		Anti-infection
	Dihydropinosylvinin is an phytoalexin, it shows antifungal activity against Cladosporium cladosporioides, Botryodiplodia theobromae, Aspergillus niger and Penicillium schlerotgenum, it also exhibits strong antibacterial ...		Anti-infection
TN1203	2,3,8-Tri-O-methylellagic acid		Antifection
	2,3,8-tri-O-Methyl ellagic acid has antimicrobial activity agaist Vibro cholera, Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, Bacillus cereus, Escherichia coli.		Antifection
TN4851	Pterodondiol		Antifection
	Pterodondiol has moderate activity against bacteria including Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis, Mycobacteium phlei and Bacillus circulans.		Antifection
T72250	4aα,7α,7aα-Nepetalactone
	4aα,7α,7aα-Nepetalactone exhibits antibacterial properties, effectively inhibiting the growth of Escherichia coli (E. coli), Pseudomonas aeruginosa, Staphylococcus aureus, Salmonella typhi, and Enterococcus faecalis.
T11219	Equisetin		Others
	Equisetin, an N-methylserine-derived acyl tetramic acid isolated from the terrestrial fungus Fusarium equiseti NRRL 5537, functions as a Quorum-sensing inhibitor (QSI) that specifically attenuates QS-regulated virulence ...		Others
TN4579	Monomethylsulochrin		Antifection
	Monomethylsulochrin shows antimicrobial activity against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus. It shows moderately inhibitory effects on the human bacterial pathogen Helic...		Antifection
TN4852	Pterodontic acid		Antifection
	Pterodontic acid and pterodondiol showed moderate activity against bacteria including Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis.		Antifection
TN2032	Pachypodol		Antifection
	Pachypodol has antibacterial and antifungal activities against Bacillus subtilis, Staphylococcus aureus, Staphylococcus faecalis, Echerichia coli, Pseudomonas aeruginosa, Candida albicans, Candida krusei and Candida gala...		Antifection
TN5229	Vibralactone B		Antifection
	Vibralactone B shows antibacterial activity, it can inhibit significantly the growth of E. coli and Pseudomonas aeruginosa, with MBC values of 50 and 100 ug/mL, respectively.		Antifection
TN3978	Epitaraxerol		Antifection
	Epitaraxerol shows moderate antifungal activity against C. albicans and low antimicrobial activity against T. mentagrophytes, A. niger, S. aureus, E. coli, P. aeruginosa, and B. subtilis.		Antifection
T83245	7-Desmethylmicrocystin-LR
	7-Desmethylmicrocystin-LR, a toxic heptapeptide, can be isolated from an axenic strain of Microcystis aeruginosa (K-139) [1].
TN5930	Ocotillone
	Ocotillone has potent antibacterial activity against Gram-negative bacteria, P. aeruginosa and S. typhimurium, that are without hemolytic activity, whereas it has weak antimicrobial activity against Gram-positive bacteri...
T83903	Polymyxin B2 sulfate
	Polymyxin B2, a significant component of polymyxin B, is an antibiotic cationic lipopeptide initially derived from B. polymyxa. This compound effectively inhibits P. aeruginosa, A. baumannii, K. pneumoniae, and E. cloaca...
T83902	Polymyxin E1 sulfate	Colistin A sulfate
	Polymyxin E1, a peptide antibiotic and key component of the cationic lipopeptide antibiotic colistin, was initially extracted from B. polymyxa. It demonstrates effectiveness against P. aeruginosa and E. coli, with minimu...
T83918	Clazamycin A hydrochloride	NSC 332188
	Clazamycin A, a microbial metabolite and antibiotic derived from Streptomyces, exhibits efficacy against several bacteria, namely S. aureus, B. anthracis, B. subtilis, E. coli, and P. aeruginosa, with minimum inhibitory ...
T38016	Hirsutide
	Hirsutide is a cyclotetrapeptide fungal metabolite produced by the entomopathogenic fungus Hirsutella. It has antibacterial activity against C. pyogenes, S. aureus, P. aeruginosa, and K. pneumonia (MICs = 25, 13, 6, and ...
TN2124	Quercetin 3-O-(6''-O-galloyl)-β-D-glucoside	Quercetin 3-O-(6''-galloyl)-beta-D-glucopyranoside	Others
	Quercetin 3-O-(6''-O-galloyl)-β-D-glucoside (Quercetin 3-O-(6''-galloyl)-beta-D-glucopyranoside) is a natural product possessing strong inhibitory activity against the growth of Microcystis aeruginosa.		Others
T75635	Microcystin-LY
	Microcystin-LY, a cyclic heptapeptide toxin produced by the cyanobacterium Microcystis aeruginosa [2], functions as a potent activator of the Nrf2 pathway, thereby inducing an oxidative stress response. Its activation ef...
TN5014	Shoreic acid		Antifection , HSV
	Shoreic acid exhibits antibacterial activity against E. coli, P. aeruginosa, S. aureus, and B. subtilis with activity indices (AI) of 0.2, 0.3, 0.5 and 0.4, respectively, it also shows antifungal activity against C. albi...		Antifection , HSV
T36403	Methyl 3,4,5-trimethoxy-2-(2-(nicotinamido)benzamido)benzoate
	Preterramide C is a fungal metabolite that has been found inA. terreus.1It is active againstS. aureus(MIC = 52.4 μM) but notE. aerogenes,P. aeruginosa, orC. albicans(MICs = >100 μM for all).2Preterramide C inhibits the g...
T75439	Angustifoline hydrochloride
	Angustifoline hydrochloride, an alkaloid derived from Lupinus angustifolius L. extract, demonstrates antimicrobial efficacy, potentially exhibiting bacteriostatic effects against S. aureus, B. subtilis, E. coli, P. aerug...
T72235	Antibacterial synergist 2
	Antibacterial synergist 2, functioning as a biofilm inhibitor, demonstrates inhibitory effects against pathogens such as S. enterica, S. aureus, P. aeruginosa, and C. albicans. This compound is applicable in research con...
T38086	Neohydroxyaspergillic Acid
	Neohydroxyaspergillic acid is a fungal metabolite produced by A. sclerotiorum that has antibiotic and antifungal activities. It inhibits the growth of P. aeruginosa, M. smegmatis, S. aureus, E. coli, K. pneumoniae, B. my...
TN4264	Isoapetalic acid		HIV Protease , Antifection
	Isoapetalic acid and apetalic acid exhibit cytotoxic activities towards both cancer cell lines(human breast cancer (MCF-7) and human lung carcinoma (A-549) cell lines) and both Gram-positive bacteria(two Gram-positive ba...		HIV Protease , Antifection
T36329	Terpendole I
	Terpendole I is a fungal metabolite that has been found in A. yamanashiensis.1 It is a weak inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 145 μM) and is active against the bacteria B. cereus and ...
TN1991	Norchelerythrine		Antifection
	Norchelerythrine shows significant inhibitory activity against Staphylococcus aureus ATCC 6538 with MIC values ranging from 12.5 to 50 ug/mL. It exhibits strong antifeeding activity in a concentration-dependant manner wi...		Antifection

天然物製品

Sclareolide

T2904

Synonym: Norambreinolide

Target: Others, Antibacterial

MOSLOFLAVONE

T5779

Synonym:

Target: IL Receptor, Virus Protease, TNF, Antibacterial

D-Menthol

TN1544

Synonym: Menthol,(+)-MENTHOL

Target: Calcium Channel, 5-HT Receptor, AChR

Lonicerin

TN1877

Synonym:

Target: Apoptosis, Antibacterial

HYPOCRELLIN B

T5780

Synonym:

Target: Apoptosis, Parasite, Antifungal

Imipenem monohydrate

T1505

Synonym: N-Formimidoyl thienamycin monohydrate,Imipenem

Target: Antibacterial, Antibiotic

Gatifloxacin hydrochloride

T8384

Synonym: AM-1155 (hydrochloride),BMS-206584 (hydrochloride),PD135432 (hydrochloride)

Target: Topoisomerase, Antibacterial, Antibiotic

(Z)-2-decenoic acid

TQ0251

Synonym: (Z)-dec-2-enoic acid,cis-2-Decenoic acid,cis-dec-2-enoic acid

Target: Others

(+)-Viroallosecurinine

T8185

Synonym: Viroallosecurinine

Target: Antibacterial

2-heptyl-3-hydroxy-4(1H)-Quinolone

T38373

Synonym: 2-heptyl-3-hydroxy-4(1H)-Quinolone,PQS,Pseudomonas Quinolone Signal

Target: Others

6-Hydroxynicotinic acid

T4816

Synonym: 6-Hydroxypyridine-3-carboxylic acid,2-Hydroxy-5-pyridinecarboxylic acid

Target: Others, Endogenous Metabolite

HQNO

T8433

Synonym:

Target: Mitochondrial Metabolism

3-O-Methylgalangin

T5707

Synonym: 3-Methylgalangin,GALANGIN-3-METHYLETHER

Target: Antibacterial

Prunin

TN2111

Synonym: Naringenin 7-0-glucoside

Target: Phosphatase, Anti-infection, Virus Protease

Sulbenicillin disodium

T8066

Synonym: Sulbenicillin Sodium

Target: Antibacterial, Antibiotic

N-Acetyltyramine

T37341

Synonym:

Target: Antibacterial

Dihydropinosylvin

TN3861

Synonym:

Target: Anti-infection

2,3,8-Tri-O-methylellagic acid

4aα,7α,7aα-Nepetalactone

7-Desmethylmicrocystin-LR

Synonym: Colistin A sulfate

Target:

Clazamycin A hydrochloride

Quercetin 3-O-(6''-O-galloyl)-β-D-glucoside

TN2124

Synonym: Quercetin 3-O-(6''-galloyl)-beta-D-glucopyranoside

Target: Antifection, HSV

Methyl 3,4,5-trimethoxy-2-(2-(nicotinamido)benzamido)benzoate

T36403

Synonym:

Target:

Angustifoline hydrochloride

T75439

Synonym:

Target:

Antibacterial synergist 2

T72235

Synonym:

Target:

Neohydroxyaspergillic Acid

Target: HIV Protease, Antifection

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-03173	OprF Protein, Pseudomonas aeruginosa, Recombinant (His)	Pseudomonas aeruginosa	E. coli
	Has porin activity, forming small water-filled channels. Also has a structural role in determining cell shape and ability to grow in low-osmolarity medium. OprF Protein, Pseudomonas aeruginosa, Recombinant (His) is expre...
TMPH-03177	RhlR Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO)	Pseudomonas aeruginosa	E. coli
	Necessary for transcriptional activation of the rhlAB genes encoding the rhamnosyltransferase. It also functions as a transcriptional activator of elastase structural gene (lasB). Binds to autoinducer molecules BHL (N-bu...
TMPH-03170	PvdA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)	Pseudomonas aeruginosa	E. coli
	PvdA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 65.5 kDa and the accession number is Q51548.
TMPH-03180	LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)	Pseudomonas aeruginosa	E. coli
	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & SUM...
TMPH-03166	Elastase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)	Pseudomonas aeruginosa	E. coli
	Cleaves host elastin, collagen, IgG, and several complement components as well as endogenous pro-aminopeptidase. Autocatalyses processing of its pro-peptide. Processes the pro-peptide of pro-chitin-binding protein (cbpD)...
TMPH-03172	OprI Protein, Pseudomonas aeruginosa, Recombinant (His)	Pseudomonas aeruginosa	E. coli
	OprI Protein, Pseudomonas aeruginosa, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 12.9 kDa and the accession number is P11221.
TMPH-03167	ToxR Protein, Pseudomonas aeruginosa, Recombinant (His)	Pseudomonas aeruginosa	E. coli
	Positive regulation of toxA gene transcription. toxR Protein, Pseudomonas aeruginosa, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 32.9 kDa and the acces...
TMPH-03174	LecA Protein, Pseudomonas aeruginosa, Recombinant (His)	Pseudomonas aeruginosa	E. coli
	D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carb...
TMPH-03169	PLC-H Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO)	Pseudomonas aeruginosa	E. coli
	Hydrolyzes sphingomyelin in addition to phosphatidylcholine. PLC-H Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted...
TMPH-03165	Beta-lactamase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)	Pseudomonas aeruginosa	E. coli
	Beta-lactamase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 56.7 kDa and the accession number is P24735.
TMPH-03175	Porin P Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)	Pseudomonas aeruginosa	E. coli
	Anion specific, the binding site has higher affinity for phosphate than chloride ions. Porin O has a higher affinity for polyphosphates (tripolyphosphate and pyrophosphate) while porin P has a higher affinity for orthoph...
TMPH-03168	Exotoxin A Protein, Pseudomonas aeruginosa, Recombinant (His & KSI)	Pseudomonas aeruginosa	E. coli
	An NAD-dependent ADP-ribosyltransferase (ADPRT). Catalyzes the transfer of the ADP ribosyl moiety of oxidized NAD (NAD(+)) onto eukaryotic elongation factor 2 (eEF-2) thus arresting protein synthesis. Has an LD(50) of 65...
TMPH-03176	LasA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)	Pseudomonas aeruginosa	E. coli
	LasA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 36.0 kDa and the accession number is P14789.
TMPH-03178	TusA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)	Pseudomonas aeruginosa	E. coli
	Sulfur carrier protein which probably makes part of a sulfur-relay system. TusA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted mol...
TMPH-03171	Lysyl endopeptidase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)	Pseudomonas aeruginosa	E. coli
	Lysine-specific endoprotease. Involved in corneal virulence. Lysyl endopeptidase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted mo...
TMPH-03179	LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO)	Pseudomonas aeruginosa	E. coli
	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & Myc...
TMPH-03164	Beta-lactamase OXA-10 Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)	Pseudomonas aeruginosa	E. coli
	Hydrolyzes both carbenicillin and oxacillin. Beta-lactamase OXA-10 Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight...
TMPY-03174	CFHR1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CFHR1 is a secreted protein belonging to the complement factor H protein family.The human complement factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1(FHL-1) a...