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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T12282 | Benzyl-α-GalNAc | O-glycosylation-IN-1 | Others |
Benzyl-α-GalNAc (O-glycosylation-IN-1) is a potent inhibitor of O-glycosylation and is used to reduce mucin on cell surfaces. | |||
T9720 | T3Inh-1 | Others | |
T3Inh-1 is an effective and selective inhibitor of ppGalNAc-T3 with an IC50 of 7 µM. T3Inh-1 prevents breast cancer cells. T3Inh-1 reduces FGF23 hormone levels in both tissue cells and mice, without causing any toxic sid... | |||
T3161L | BACE-IN-1 acetate | BACE-IN-1 acetate (350228-37-4,Free base) | BACE |
BACE-IN-1 acetate (BACE-IN-1 acetate (350228-37-4,Free base)) has been used as β-site amyloid precursor protein (APP) cleaving enzyme-1 (BACE1) inhibitor in BACE1 inhibitor assay. β-Site amyloid precursor protein (APP) c... | |||
TNU1108 | (R)-1,4-Anhydro-2-O-(2,4-dimethoxybenzoyl)-3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-4-sulfinyl-D-ribitol | ||
Carbohydrate Derivatives; Ready for glycosylation | |||
T38976 | MUC1, mucin core | MUC1, mucin core | |
MUC1, mucin core is a type I transmembrane glycoprotein that is characterized by its overexpression and abnormal glycosylation in carcinoma cells. It specifically binds to domain 1 of ICAM-1. | |||
T71844 | Methyl potassium malonate | ||
Methyl potassium malonate is a protein advanced glycosylation inhibitor. | |||
T36474 | TunR1 | ||
TunR1 is an antibiotic and derivative of tunicamycin .1It is active againstB. subtilis(MIC = 0.3 μg/ml) and increases the efficacy of the β-lactam antibiotics oxacillin , methicillin , and penicillin G againstB. subtilis... | |||
T83602 | (+)-Chloroquine | ||
(+)-Chloroquine, an aminoquinoline drug, inhibits the in vitro terminal glycosylation of angiotensin-converting enzyme 2 (ACE-2) [1]. | |||
T80089 | HCV-1 e2 Protein (554-569) (TFA) | ||
HCV-1 e2 Protein (554-569) TFA, an antigenic segment of the hepatitis C virus envelope 2 (e2) protein, encompasses a potential N-glycosylation site implicated in modulating immune recognition of e2 [1]. | |||
T36475 | TunR2 | ||
TunR2 is an antibiotic and derivative of tunicamycin .1It is active againstB. subtilis(MIC = 0.3 μg/ml) and increases the efficacy of the β-lactam antibiotics oxacillin , methicillin , and penicillin G againstB. subtilis... | |||
T36134 | 3,4,6-Tri-O-benzyl-β-D-Mannopyranose 1,2-(methyl orthoacetate) | ||
3,4,6-Tri-O-benzyl-β-D-mannopyranose 1,2-(methyl orthoacetate) is a synthetic intermediate used in glycosylation reactions. Typically, the methyl orthoester protecting group is first removed by mild acid hydrolysis, prod... | |||
T76514 | HCV-1 e2 Protein (554-569) | ||
HCV-1 e2 Protein (554-569), a primary antigenic region within the Hepatitis C Virus envelope 2 (e2) protein, features a putative N-glycosylation site believed to impact the immune recognition of e2 [1]. | |||
T72917 | D-threo-PDMP | ||
D-threo-PDMP is a potent inhibitor of glucoceramide synthase (GCS), effectively reducing cell surface glycosphingolipids by inhibiting glycosylation. It also decreases the axon plexus's total length and the number of axo... | |||
T12148L | N-Desmethyltamoxifen | Others | |
N-Desmethyltamoxifen, the principal metabolite of tamoxifen in humans, serves as an efficacious modulator of ceramide metabolism within human AML cells by inhibiting ceramide glycosylation, hydrolysis, and sphingosine ph... | |||
T73770 | Galactosylhydroxylysine hydrochloride | ||
Galactosylhydroxylysine hydrochloride, a bone collagen component generated through hydroxylysine's post-translational glycosylation, is liberated during bone resorption. Its levels increase in cases of metabolic bone los... | |||
TNU1050 | 3-Deoxy-1,2;5,6-di-O-isopropylidene-D-glucofuranose | ||
3-Deoxy-1,2;5,6-di-O-isopropylidene-D-glucofuranose is a polysaccharide oligosaccharide. It is used in glycosylation synthesis and can be custom synthesized for use as a carbohydrate in drugs. It has antiviral activity a... | |||
T74092 | Cyanine5 alkyne | ||
Cyanine5 alkyne (Alkyne-Cy5), a fluorescent dye, labels azide proteins for analyzing post-translational modifications, such as glycosylation. Additionally, it serves as a mitochondrial OXPHOS inhibitor, curtailing the pr... | |||
T79928 | Phosphomannose isomerase | ||
Phosphomannose isomerase, the initial enzyme in GDP-Man biosynthesis, catalytically facilitates the interconversion of fructose-6-phosphate (Fru6P) and mannose-6-phosphate (Man6P), playing a crucial role in cell wall syn... | |||
T64475 | FMOC-L-THR | ||
FMOC-L-THR (AZP-531) is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight. The O-glycosidic linkage and the O-acetyl protection in this building block is stable to both piperidine ... | |||
T35890 | Pentosidine | ||
Advanced glycation end products (AGEs) are compounds formed by non-enzymatic chemical reactions following the bonding of sugars to proteins or lipids during diabetes, uremia, aging, rheumatic arthritis, and other conditi... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TN2158 | Robinetin | 3,3',4',5',7-Pentahydroxyflavone | Anti-infection , HIV Protease , Antibacterial |
Robinetin (3,3',4',5',7-Pentahydroxyflavone) has antioxidant and antiradical activities, inhibits EYPC membrane lipid peroxidation and HbA glycosylation with high efficiency. | |||
T22468 | 1-Deoxymannojirimycin hydrochloride | Others , Influenza Virus , HIV Protease | |
α-mannosidase I inhibitor | |||
T13229 | Tunicamycin | Influenza Virus , Antibacterial , Antibiotic , Antifungal | |
Tunicamycin is a mixture of antibiotics that inhibit N-linked glycosylation by blocking GlcNAc phosphotransferase (GPT). Tunicamycin has antitumor activity, as well as anti-bacterial, anti-fungal, and anti-viral activity... | |||
T3S2156 | Chrysin 7-O-beta-gentiobioside | Chrysin 7-O-β-gentiobioside | Others |
Chrysin 7-O-beta-gentiobioside (Chrysin 7-O-β-gentiobioside), a glycosylation product of Chrysin, is from Spartium junceum. | |||
T4812 | D-Mannose | D-(+)-Mannose | Endogenous Metabolite |
D-Mannose (D-(+)-Mannose) is a carbohydrate. D-Mannose plays an important role in human metabolism, especially in the glycosylation of specific proteins. | |||
T3881 | Vaccarin | Integrin , Akt , PERK , AMPK | |
Vaccarin is a major flavonoid glycoside in Vaccariae semen, its biotransformation pathways involves methylation, hydroxylation, glycosylation and deglycosylation. | |||
TN2331 | Eleutheroside B1 | Influenza Virus | |
Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits l... | |||
TN2122 | Quercetin 3-gentiobioside | Quercetin-3-gentiobioside | Reductase |
Quercetin 3-gentiobioside (Quercetin-3-gentiobioside) is an inhibitor of AR and AGE formation and can be extracted from A. iwayomogi.Quercetin 3-gentiobioside inhibits the biological activity of aldose reductase (AR) and... | |||
T4843 | 2,2-Dihydroxyacetic acid | Formylformic acid,Glyoxylic acid monohydrate | Others , Endogenous Metabolite |
2,2-Dihydroxyacetic acid (Formylformic acid) is an intermediate in the glyoxalate cycle, which enables certain organisms to convert fatty acids to carbohydrates.2,2-Dihydroxyacetic acid has been found to be associated wi... | |||
T4809 | Pyrimidine | Metadiazine | Others , Endogenous Metabolite |
Pyrimidine (Metadiazine)s are heterocyclic, six-membered, nitrogen-containing carbon ring structures, with uracil, cytosine and thymine being the basal structures of ribose-containing nucleosides (uridine, cytidine, and ... | |||
T4825 | D-(+)-Xylose | D(+)-Xylose,(+)-Xylose,Wood sugar | Endogenous Metabolite |
D-(+)-Xylose (Wood sugar) is an aldopentose - a monosaccharide containing five carbon atoms and an aldehyde functional group. It has chemical formula C5H10O5 and is 40% as sweet as sucrose. Xylose is also found in mucopo... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-02927 | RAGE Protein, Human, Recombinant (His) | Human | HEK293 Cells |
RAGE Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.5 kDa and the accession number is A0A1U9X785. | |||
TMPY-02881 | RAGE Protein, Human, Recombinant | Human | HEK293 Cells |
RAGE Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35 kDa and the accession number is A0A1U9X785. | |||
TMPY-02342 | MIF Protein, Mouse, Recombinant | Mouse | E. coli |
MIF Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 12.5 kDa and the accession number is P34884. | |||
TMPY-02145 | MIF Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
MIF Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.8 kDa and the accession number is P34884. | |||
TMPY-01675 | RAGE Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
RAGE Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.3 kDa and the accession number is Q62151-1. | |||
TMPY-01716 | RAGE Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
RAGE Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.1 kDa and the accession number is A0A1U9X785. | |||
TMPY-02095 | MIF Protein, Human, Recombinant (His) | Human | HEK293 Cells |
MIF Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.8 kDa and the accession number is P14174. | |||
TMPY-00365 | GALNT7 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
GalNAc-transferase-7 (GALNT7) is essential for the regulation of cell proliferation and has been implicated in tumorigenesis. Colorectal cancer (CRC) arises in a multistep molecular network process, which is from either ... | |||
TMPH-03083 | CrtX Protein, Pantoea ananas, Recombinant (His & Myc) | Pantoea ananas | Baculovirus Insect Cells |
Catalyzes the glycosylation reaction which converts zeaxanthin to zeaxanthin bis(beta-D-glucoside). The reaction proceeds in two steps with the monoglucoside as an intermediate. CrtX Protein, Pantoea ananas, Recombinant ... | |||
TMPH-03512 | GT Protein, Solanum melongena, Recombinant (His & Myc) | Solanum melongena | Baculovirus Insect Cells |
In the presence of other necessary color factors, this glycosylation reaction allows the accumulation of anthocyanin pigments. GT Protein, Solanum melongena, Recombinant (His & Myc) is expressed in Baculovirus insect cel... | |||
TMPH-03084 | CrtX Protein, Pantoea ananas, Recombinant (E. coli, His & Myc) | Pantoea ananas | E. coli |
Catalyzes the glycosylation reaction which converts zeaxanthin to zeaxanthin bis(beta-D-glucoside). The reaction proceeds in two steps with the monoglucoside as an intermediate. CrtX Protein, Pantoea ananas, Recombinant ... | |||
TMPH-03442 | PMT5 Protein, S. cerevisiae, Recombinant (His) | Saccharomyces cerevisiae | E. coli |
Protein O-mannosyltransferase involved in O-glycosylation which is essential for cell wall rigidity. Forms a heterodimeric complex with PMT3 and more rarely with PMT2 to transfer mannose from Dol-P-mannose to Ser or Thr ... | |||
TMPJ-01092 | MGAT2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Mannoside Acetylglucosaminyltransferase 2 (MGAT2) is a single-pass type II membrane protein that contains the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal... | |||
TMPH-03441 | PMT3 Protein, S. cerevisiae, Recombinant (His) | Saccharomyces cerevisiae | E. coli |
Protein O-mannosyltransferase involved in O-glycosylation which is essential for cell wall rigidity. Forms a heterodimeric complex with PMT5 and more rarely with PMT1 to transfer mannose from Dol-P-mannose to Ser or Thr ... | |||
TMPJ-00160 | EMMPRIN/CD147 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen β-chain. EMMPRIN is a transmembrane ... | |||
TMPK-00286 | Siglec-9 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Siglec-9 is a sialic-acid-binding lectin expressed predominantly on myeloid cells. Aberrant glycosylation occurs in essentially all types of cancers and results in increased sialylation. Thus, when the mucin MUC1 is expr... | |||
TMPK-00287 | Siglec-9 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Siglec-9 is a sialic-acid-binding lectin expressed predominantly on myeloid cells. Aberrant glycosylation occurs in essentially all types of cancers and results in increased sialylation. Thus, when the mucin MUC1 is expr... | |||
TMPJ-01190 | SPESP1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Sperm Equatorial Segment Protein 1 (SPESP1) is a member of the SPESP1 family. SPESP1 is highly expressed in the testis, where it is localized to the acrosome of postmeiotic stages of spermiogenesis; it is expressed at lo... | |||
TMPJ-01364 | LMCD1 Protein, Human, Recombinant (His) | Human | E. coli |
LMCD1 is transcriptional cofactor which contains a cysteine-rich domain in the N-terminal region and 2 LIM domains in the C-terminal region. It also has several potential phosphorylation and N-myristoylation sites and a ... | |||
TMPJ-01223 | GALNTL1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Putative polypeptide N-acetylgalactosaminyltransferase-like protein 1, also known as Polypeptide GalNAc transferase-like protein 1, Protein-UDP acetylgalactosaminyltransferase-like protein 1, UDP-GalNAc:polypeptide N-ace... | |||
TMPJ-00200 | EpCAM/TROP1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Epithelial Cellular Adhesion Molecule (Ep-CAM), also known as EGP314, mEGP314, Protein 289A, Tumor-associated calcium signal transducer 1, CD326, belongs to the EPCAM family. Its’ monomer subunit structure interacts with... | |||
TMPY-03611 | PMM2 Protein, Human, Recombinant (His) | Human | E. coli |
Phosphomannomutase 2, also known as PMM2 and CDG1, belongs to the eukaryotic PMM family. Phosphomannomutase 2 catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate. Mannose 1-phosphate is a precursor ... | |||
TMPY-01865 | BLMH Protein, Mouse, Recombinant (His) | Mouse | E. coli |
The papain superfamily member bleomycin hydrolase (BLMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution. The only known activity of the enzyme is metabolic inactivation of the glycopeptide... | |||
TMPY-01948 | COQ7 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Ubiquinone biosynthesis protein COQ7 homolog, also known as Coenzyme Q biosynthesis protein 7 homolog, Timing protein clk-1 homolog and COQ7, is a mitochondrion inner membrane and peripheral membrane protein which bel... | |||
TMPY-06585 | C1s Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Complement is an integral component of the adaptive and innate immune systems and represents one of the major effector systems for the immune responses. The classical complement pathway is triggered by C1, a complex comp... | |||
TMPY-03962 | AFM Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Afamin is an 87 kDa glycoprotein with five predicted N-glycosylation sites. Afamin's glycan abundance contributes to conformational and chemical inhomogeneity presenting great challenges for molecular structure determina... | |||
TMPJ-00438 | SECTM1A Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
SECTM1A (secreted and transmembrane 1A), is 192 amino acid (aa) protein, appears to share structural and functional characteristics with other SECTM1 proteins. Human SECTM1 can be found either found as an approximately 2... | |||
TMPJ-00698 | BTNL2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Butyrophilin-like 2 (BTNL2) is a member of the BTN/MOG Ig-superfamily and functions as a negative regulator of immune cell activation. Mouse BTNL2 is type I transmembrane glycoprotein that contains an extracellular domai... | |||
TMPY-01189 | GFPT1 Protein, Human, Recombinant | Human | E. coli |
Glutamine:fructose-6-phosphate amidotransferase 1 (GFAT), also known as GFPT1, is a member of the N-terminal nucleophile aminotransferases and the first rate-limiting enzyme for the entry of glucose into the hexosami... | |||
TMPY-02480 | Chymotrypsin C Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Chymotrypsin C (abbreviated for CTRC), also known as caldecrin or elastase4, is a digestive enzyme of the peptidase S1 family. This enzyme is synthesized as an inactivate chymotrypsinogen. On cleavage by trypsin into two... | |||
TMPJ-00330 | GPC1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
The Glypicans are a small multigene family of GPI-linked proteoglycans that play a key role in growth factor signaling. Human Glypican 1 (GPC1) is synthesized as a 558 amino acid (aa) preproprecursor that contains a 23 a... | |||
TMPJ-00521 | CHL2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Mouse Chordin-Like 2, also known as CHL2, is a novel chordin family member with structural homology to CHL1 which is implicated in tumor angiogenesis. The mouse CHL2 gene encodes a 426 amino acids (aa) protein with a 25... | |||
TMPJ-00837 | LAMP1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Lysosomal associated membrane protein 1 (LAMP1) is an approximately 120 kDa transmembrane glycoprotein that is a major protein component of lysosomal membranes. Mature mouse LAMP1 consists of a 346 amino acid (aa) intral... | |||
TMPJ-00605 | GPVI Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Glycoprotein VI (GPVI) is a 63 kDa platelet/megakaryocyte-specific type I transmembrane glycoprotein of the immunoglobulin superfamily that is an important collagen receptor and initiator of platelet activation, aggregat... | |||
TMPJ-00055 | Podoplanin Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Podoplanin belongs to the podoplanin family, also known as Glycoprotein 38. Podoplanin is synthesized as a 172 amino acid (aa) precursor with a 22 aa signal sequence, a 119 aa extracellular domain (ECD), a 21 aa transmem... | |||
TMPY-01027 | Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Mast Cell Protease 1 (MMCP-1), also known as MCP-1, MCPT-1 and β-chymase, is a member of the Chymase family of chymotrypsin-like serine proteases. MCPT-1 is a 26 kDa β-chymase that is a component of mast cell granules. I... |
カタログ番号 | 製品名 | ||
---|---|---|---|
L9700 | Endoplasmic Reticulum Stress Compound Library | 193 compounds | |
A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS); |