|
T21902 |
ML351
|
|
Lipoxygenase
|
|
ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM). |
|
T4552 |
Fursultiamine
|
Diteftin,Judolor,Alinamin F |
Others
|
|
Fursultiamine (Alinamin F) is a disulfide derivative of thiamine, or an allithiamine. It has potential uses in the treatment of vitamin B1 deficiency. |
|
T7601L |
Carbetocin acetate
|
Carbetocin acetate(37025-55-1 free base) |
Oxytocin Receptor
|
|
Carbetocin acetate is an obstetric drug used to control postpartum hemorrhage and bleeding after giving birth. |
|
T15247 |
ESI-05
|
NSC 116966 |
cAMP
|
|
ESI-05 (NSC-116966) is a specific EPAC2 (exchange protein directly activated by cAMP 2) antagonist (IC50: 0.4 μM). ESI-05 inhibits cAMP-mediated activation of EPAC2, as well as EAPC2, mediated Rap1 activation. |
|
T11571 |
HLY78
|
4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine |
Wnt/beta-catenin
|
|
HLY78 (4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine) targets the DIX domain of Axin, is an activator of the Wnt/β-catenin signaling pathway and can enhance Axin-LRP6 binding to promote Wnt signaling. |
|
T22285 |
Carboprost
|
15(S)-15-Methyl Prostaglandin F2α,15-Methyl-PGF2α |
Prostaglandin Receptor
|
|
Carboprost (15(S)-15-Methyl Prostaglandin F2α) is a synthetic prostaglandin analogue of PGF2α which has the effect of oxytocic. Carboprost is commonly used to restore uterine tone. |
|
T7601 |
Carbetocin
|
|
Oxytocin Receptor
|
|
Carbetocin is an obstetric drug used to control postpartum hemorrhage and bleeding after giving birth. |
|
T70470 |
CM-352
|
|
MMP
|
|
CM-352 is a metalloproteinase inhibitor that reduces brain damage and improves functional recovery in rat models of cerebral hemorrhage. |
|
T8857 |
LJP-1586 HCl
|
LJP 1586,LJP-1586 hydrochloride,LJP-1586,LJP1586 |
Others
|
|
LJP-1586 HCl, a highly selective inhibitor of vascular adhesion protein-1 (VAP-1), exhibits antiinflammation effect by reducing adhesion molecule expression and immune cell infiltration after intracerebral hemorrhage (IC... |
|
T11662L |
INT-777
|
S-EMCA |
GPCR19
|
|
|
|
T50100 |
3-hydroxy-3-phenylpentanamide
|
|
Others
|
|
3-hydroxy-3-phenylpentanamide is a chiral compound belonging to the class of beta-hydroxyamides. In neurology, it has been shown to have neuroprotective effects against ischemic brain injury and cerebral hemorrhage. In p... |
|
T3560 |
Desmethylanethol trithione
|
ADT-OH |
VEGFR
,
Akt
|
|
Desmethylanethol trithione (ADT-OH) is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. In the in vitro glucose-oxygen deprivation (OGD) model, Desmethylanethol trithione markedly... |
|
T61677 |
PiCRAC-1
|
|
|
|
piCRAC-1 is a powerful inhibitor of the photoinducible Ca2+ release-activated Ca2+ (CRAC) channel. It effectively alleviates thrombocytopenia and hemorrhage [1]. |
|
T38058 |
Cimetidine sulfoxide
|
|
|
|
Cimetidine sulfoxide (Cimetidine sulphoxide) is a metabolite of Cimetidine, functioning as a histamine H2-receptor antagonist with potential applications in treating peptic ulcer disease and upper gastrointestinal hemorr... |
|
T11152 |
Edaravone-d5
|
MCI-186 D5 |
Others
|
|
Edaravone, a novel and potent free radical scavenger, effectively prevents MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. Its deuterium-labeled variant, Edaravone D5, retains the origin... |
|
TP1953 |
PG-931
|
PG 931 |
|
|
Potent and selective melanocortin 4 (MC4) receptor agonist (IC50 values are 0.58 and 55 nM for human MC4 and MC3 receptors respectively). Produces a rapid and dose dependent restoration of cardiovascular and respiratory ... |
|
T70186 |
Methazolamide-d6
|
|
|
|
Methazolamide-d6 is intended for use as an internal standard for the quantification of methazolamide by GC- or LC-MS. Methazolamide is a carbonic anhydrase inhibitor. It reduces intraocular pressure and cerebrospinal flu... |
|
T73989 |
Tirilazad
|
|
|
|
Tirilazad, a nonglucocorticoid 21-aminosteroid, serves to inhibit lipid peroxidation. It mitigates the effects of trauma-induced brain or spinal cord injury, as well as damage resulting from stroke, ischemia, and reperfu... |
|
T83851 |
Tat-QFNP12 TFA
|
|
|
|
Tat-QFNP12 is a peptide that combines a transcriptional transactivator (Tat) transmembrane domain with an inhibitor targeting the interaction between N-Myc downstream regulated gene 2 (NDRG2) and protein phosphatase Mg2+... |
