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T10328 |
Anti-parasitic agent 3
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Others
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Anti-parasitic agent 3 is an anti-parasitic agent active against drug-resistant parasites. |
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T0395 |
Pyrantel tartrate
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Banminth |
Antibiotic
,
Parasite
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Pyrantel tartrate (Banminth) is broad spectrum anthelmintic for livestock. |
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T1259 |
Pyrantel pamoate
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Pyrantel embonate |
Others
,
Antibiotic
,
Parasite
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Pyrantel pamoate (Pyrantel embonate) is a depolarizing neuromuscular blocking agent. |
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T1172 |
Diclazuril
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R-64433 |
Antibiotic
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Parasite
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Diclazuril (R-64433) is a coccidiostat. |
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T1546 |
Nitazoxanide
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NSC 697855 |
Others
,
Influenza Virus
,
Parasite
,
Autophagy
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Nitazoxanide (NSC-697855) is a synthetic benzamide with antiprotozoal activity. Nitazoxanide exerts its antiprotozoal activity by interfering with the pyruvate ferredoxin/flavodoxin oxidoreductase dependent electron tran... |
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T0850 |
Primaquine diphosphate
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Primaquine phosphate,Primaquine bisphosphate |
Antibiotic
,
Parasite
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Primaquine diphosphate is the phosphate salt form of primaquine, a synthetic, 8-aminoquinoline derivative with antimalarial properties. Although its mechanism of action is unclear, primaquine bind to and alter the proper... |
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T8999 |
Soporidine
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Others
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Soporidine is a strigolactone (SL) antagonist and inhibitor of germination in their biological assays. It binds AtHTL and specifically interferes with SL signaling. |
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T61538 |
Antiparasitic agent-10
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Antiparasitic agent-10 (Compound 94) is a potent anti-parasitic agent specifically designed to target and combat parasitic infections. It demonstrates notable anti-schistosomal activity, particularly against adults of Sc... |
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T83024 |
Antiparasitic agent-20
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Parasite
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Antiparasitic Agent-20 (Compound 1p) exhibits broad-spectrum activity as a parasitic inhibitor, demonstrating efficacy against T. brucei and T. cruzi with EC50 values of 0.09 µM and 14.1 µM, respectively [1]. |
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T61683 |
Antiparasitic agent-9
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|
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Antiparasitic agent-9 (compound 47) is a highly active and orally administered antiparasitic agent, exhibiting potent antiparasitic efficacy against the human parasite [1]. |
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T83025 |
Antiparasitic agent-19
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Antiparasitic Agent-19 (Compound 40) is a broad-spectrum antiparasitic with minimal toxicity to Trypanosoma brucei, Leishmania infantum, and Trypanosoma cruzi [1]. |
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T79415 |
Antiparasitic agent-18
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Parasite
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Antiparasitic agent-18 (compound 3a) exhibits potent and selective antiprotozoal activity, demonstrating effective inhibition of T. brucei (EC 50 =0.4 µM), T. cruzi (EC 50 =0.21 µM), and L. donovani (EC 50 =0.26 µM) [1]. |
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T61160 |
Antiparasitic agent-2
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Antiparasitic agent-2 (compound 8a) exhibits potent antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi), with IC50s of 7.28 μM and 2.30 μM, respectively. Additionally, it dem... |
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T74773 |
Antiparasitic agent-14
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Antiparasitic Agent-14 is a potent antiparasitic compound with demonstrated cytotoxicity and antiparasitic activity, effectively inhibiting the growth of trypomastigote and amastigote forms [1]. |
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T78966 |
Antiparasitic agent-17
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Parasite
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Antiparasitic Agent-17 (compound 5u), an orally active antiparasitic, demonstrates inhibition against both Chloroquine-sensitive (Pf3D7) and Chloroquine-resistant (PfK1) strains, with IC50 values of 0.96 μM and 1.67 μM, ... |
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T60519 |
Antiparasitic agent-4
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|
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Antiparasitic agent-4 (compound 4q) exhibits high antiparasitic activity with IC50 of 8.51 μM for Leishmania infantum (L. infantum) and IC50 of 2.20 μM for Trypanosoma cruzi ( T. cruzi ). Antiparasitic agent-4 is also cy... |
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T61221 |
Antiparasitic agent-8
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|
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Antiparasitic agent-8 (Compound 9) exhibits potent antiparasitic activity against Hymenolepis nana, while demonstrating low levels of cytotoxicity [1]. |
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T61641 |
Antiparasitic agent-5
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|
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Antiparasitic agent-5 (compound 8h) exhibits potent selectivity as an antiparasitic agent against Leishmania infantum (L. infantum), with an IC50 value of 2.50 μM. Additionally, this compound displays cytotoxic effects o... |
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T61245 |
Antiparasitic agent-7
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Antiparasitic agent-7 (compound 5d) displays specific antiparasitic activity against Leishmania infantum (L. infantum), exhibiting an IC50 value of 2.85 μM. Additionally, Antiparasitic agent-7 demonstrates cytotoxicity a... |
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T61001 |
Antiparasitic agent-6
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|
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Antiparasitic agent-6 (compound 5b) shows selectively antiparasitic activity against Leishmania infantum (L. infantum) (IC 50 = 3.89 μM). Antiparasitic agent-6 also exhibits certain cytotoxicity against HepG2 with a CC50... |
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T16705 |
Quinfamide
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WIN-40014 |
Others
,
Parasite
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Quinfamide is a compound with the potential to treat tropical parasitic infections such as Amoebiasis and Helminthiasis. |
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T11013L2 |
Levorotation nimorazole phosphate ester TFA
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Others
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Levorotation nimorazole phosphate ester TFA is an anti-anaerobic and anti-parasitic agent. |
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T11013L1 |
Dextrorotation nimorazole phosphate ester TFA
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Others
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Dextrorotation nimorazole phosphate ester TFA is an anti-anaerobic and anti-parasitic agent. |
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T0838 |
Triclabendazole
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CGA89317 |
Microtubule Associated
,
Parasite
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Triclabendazole (CGA89317) has been used in trials studying Parasitic Disease. |
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T0356 |
Nitromide
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3, 5-Dinitrobenzamide,3,5-Dinitrobenzamide |
Parasite
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Nitromide (3,5-Dinitrobenzamide) is an anti-parasitic drug. |
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T12022 |
Metronidazole Benzoate
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Benzoyl metronidazole |
Antibacterial
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Metronidazole Benzoate (Benzoyl metronidazole) is a derivative of Metronidazole and benzoic acid, which has antibacterial, anti-parasitic and anti-trichomonas functions and is often used to treat infections caused by ana... |
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T37514 |
Hydroxy Dimetridazole
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Drug Metabolite
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Dimetridazole is a nitroimidazole-based compound with antibacterial and anticoccidial activity. It was once widely used in the treatment of parasitic infections in poultry, cattle, swine and farmed fish until suspected t... |
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T2214 |
Flumethrin
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Others
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Flumethrin is a pyrethroid insecticide. It is used externally in veterinary medicine against parasitic insects and ticks on cattle, sheep, goats, horses, and dogs, and the treatment of parasitic mites in honeybee colonie... |
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T71419 |
Diclazuril K
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|
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Diclazuril K is a coccidiostat and GAPDH inhibitor used to prevent parasitic contamination of livestock and poultry feed. |
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T71418 |
Diclazuril Na
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Diclazuril Na is a coccidiostat and GAPDH inhibitor used to prevent parasitic contamination of livestock and poultry feed. |
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T39425 |
Umifoxolaner
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Umifoxolaner is an anti-parasitic agent (veterinary). |
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T33637 |
Neostibosan
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Stibanilic acid,693B,Astaril,Ethylstibamine,p-Aminobenzenestibonic acid,Bayer 693 |
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Neostibosan is an arsenic-containing parasitic agent. Due to the activity of arsenic on visceral L/Ashmaniasis, one of the pentvalent antimony, which is less toxic, is synthesized and has potential activity on tumor cell... |
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T70938 |
SN00799639
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|
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SN00799639, also known as SN639, is a potent inhibitor of the motility and development of parasitic larvae of Haemonchus contortus, a blood-feeding parasitic nematode of major economic importance in ruminants. SN639 dis... |
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T11013 |
Dextrorotation nimorazole phosphate ester
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Others
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Dextrorotation nimorazole phosphate ester is an anti-anaerobic and anti-parasitic agent. D-morpholine ornidazole organic phosphate is a newly developed, highly efficient, well-tolerated fourth-generation nitroimidazole d... |
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T69469 |
Panepoxydone
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Panepoxydone, an inhibitor of NF-κB activation, disrupts NF-κB-mediated signal transduction through the inhibition of IκB phosphorylation. Displaying antitumor, anti-inflammatory, antimalarial, and anti-parasitic activit... |
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T71917 |
FFK29
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|
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FFK29 is a synthetic class II HDACi (Histone deacetylase inhibitors) which have have recently emerged as novel therapeutic options for treating various protozoan and parasitic diseases. While these HDACi demonstrated a n... |
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T80625 |
Fosthiazate
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|
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Fosthiazate is a broad-spectrum nematicide that combats a range of plant parasitic nematodes such as Meloidogyne spp., Globodera spp., and Pratylenchus spp., by inhibiting acetylcholinesterase synthesis [1]. |
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T72519 |
Niclosamide sodium
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BAY2353 sodium |
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Niclosamide sodium (BAY2353), an orally active antihelminthic agent employed in parasitic infection research, serves as a potent STAT3 inhibitor, demonstrating an IC50 of 0.25 μM in HeLa cells. Additionally, this compoun... |
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T35745 |
Marcfortine A
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|
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Marcfortine A is an indole alkaloid originally isolated from P. roqueforti. It has nematocidal activity against the parasitic nematode H. contortus (LD99 = 0.06 μg/ml) and inhibits motility of adult worms (EC50 = 2 μM).,... |
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T75536 |
Koshidacin B
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Koshidacin B, a cyclic tetrapeptide, exhibits potent antiplasmodial activity, evidenced by its ability to inhibit Plasmodium falciparum strains FCR3 and K1 with IC50 values of 0.89 μM and 0.83 μM, respectively. It has be... |
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T37757 |
Tyvelose
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Tyvelose is an unusual 3,6-dideoxyhexose terminal sugar and the immunodominant component of glycoprotein antigens in the parasitic helminth T. spiralis, which is responsible for trichinosis in humans. It is produced in h... |
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T35419 |
τ-Fluvalinate
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τ-Fluvalinate is a pyrethroid acaricide.1It induces tail currents in Western honeybee (A. mellifera) voltage-gated sodium channels (AmNav1) expressed inXenopusoocytes (EC50= 60 nM). It also induces tail currents in honey... |
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T83887 |
SLU-10482
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|
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SLU-10482, an antiparasitic agent, effectively reduces C. parvum parasitic load in HCT-8 cells with an EC50 value of 0.07 µM. It exhibits lower affinity for human ether-a-go-go (hERG; Kd = 43 µM) compared to its counterp... |
