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T15418 |
GS-6201
|
CVT-6883 |
Adenosine Receptor
|
|
GS-6201 (CVT-6883) is a selective antagonist of adenosine A2B receptor. GS-6201 shows high affinity and selectivity for the human adenosine A2B receptors with a Ki of 22 nM. |
|
T13995 |
1-Methyl-7-nitroisatoic anhydride
|
1M7 |
Others
|
|
1-Methyl-7-nitroisatoic anhydride (1M7) is a reagent. It detects local nucleotide flexibility, for probing 2'-hydroxyl reactivity. |
|
T33389 |
Minalrestat
|
ARI509,WAY-121509,WAY121509,WAYARI-509,ARI-509,WAY-ARI-509 |
Reductase
|
|
Minalrestat(ARI-509) is an orally active and potent aldose reductase inhibitor for the study of impaired microvascular reactivity in diabetic patients. |
|
T15543 |
IA-Alkyne
|
N-Hex-5-ynyl-2-iodo-acetamide,Iodoacetamide-alkyne |
TRP/TRPV Channel
|
|
IA-Alkyne (Iodoacetamide-alkyne) is a TRP channel (TRPC) agonist. IA-Alkyne can be used to develop an isotopically tagged probe for quantitative cysteine-reactivity profiling. It also has the potential for the study of r... |
|
T9438 |
2,3,4-Trifluoro-5-Nitro-Benzoic Acid
|
|
Others
|
|
2,3,4-Trifluoro-5-Nitro-Benzoic Acid is a useful intermediate in organic synthesis. It has been used to study the effect of fluorine substitution on the reactivity of organic molecules. It has also been used to study the... |
|
T8952 |
Bis(p-methoxyphenyl)iodonium bromide
|
Di(p-anisyl)iodonium Bromide |
Others
|
|
bis(p-methoxyphenyl)iodonium bromide (Di(p-anisyl)iodonium Bromide) is a bromide salt consisting of two p-methoxyphenyl iodonium molecules linked together by a bromide ion. It has been used as a reagent in the synthesis ... |
|
T6029 |
ONX-0914
|
ONX0914,PR-957,ONX 0914 |
Proteasome
,
HIV Protease
,
Antibacterial
|
|
ONX-0914 (PR-957) is an effective and specific immunoproteasome inhibitor, which has minimal cross-reactivity for the constitutive proteasome. |
|
T8670 |
Fmoc-L-2-cyanophenylalanine
|
|
Others
|
|
fmoc-L-2-cyanophenylalanine is a derivative of the amino acid phenylalanine. Due to its excellent reactivity and stability, it is widely used in peptide synthesis, as well as in the synthesis of a variety of other biolog... |
|
TD0102 |
1,3-Diphenylisobenzofuran
|
DPBF |
Others
|
|
1,3-Diphenylisobenzofuran (DPBF) is a fluorescent probe. It possesses a highly specific reactivity towards singlet oxygen forming an endoperoxide which decomposes to give 1,2-dibenzoylbenzene. 1,3-Diphenylisobenzofuran c... |
|
T20751 |
Carumonam
|
|
|
|
Carumonam, an antibiotic, could enhance the reactivity of Escherichia coli with mono- and polyclonal antisera to rough Escherichia coli J5. |
|
T31538 |
Divinyl ketone
|
Vinyl ketone |
|
|
Divinyl ketone is a kind of high reactivity, easy polymerization of multifunctional cyclization reagent. |
|
T40616 |
8-Azido-ATP
|
8-Azidoadenosine 5'-triphosphate,8-N3-ATP,8-Azido-ATP |
|
|
8-Azido-ATP is a nucleotide analog that demonstrates photo-reactivity properties. It offers utility in the precise labeling and identification of proteins, particularly those involved in DNA-dependent RNA polymerase acti... |
|
T35354 |
BSTFA-TMCS
|
|
Others
|
|
The combination of BSTFA and TMCS is the preferred reagent for trimethylsilylation of alcohols, alkaloids, amines, biogenic amines, carboxylic acids, phenols, and steroids. TMCS increases the reactivity of BSTFA. BSTFA-T... |
|
T61794 |
LASSBio-1632
|
|
|
|
LASSBio-1632 is a novel anti-asthmatic lead candidate that selectively inhibits PDE4A and PDE4D isoenzymes, leading to the suppression of airway hyper-reactivity (AHR) and TNF-α production in lung tissue. With high exper... |
|
T82908 |
BDC2.5 mimotope 1040-31 TFA
|
|
|
|
BDC2.5 mimotope 1040-31 TFA, a specific agonistic peptide for the diabetogenic T cell clone BDC2.5, exhibits strong reactivity with BDC2.5 T-cell receptor (TCR) transgenic (Tg)+ T cells [1] [2]. |
|
T77281 |
DSPE-Thiol
|
|
|
|
DSPE-Thiol, a thiol-capped phospholipid, demonstrates selective reactivity with maleimide and is employed in the synthesis of phospholipid dimers [1]. |
|
T76581 |
HHV-2 Envelope Glycoprotein G (552-574)
|
|
|
|
HHV-2 Envelope Glycoprotein G (552-574), an immunodominant region within glycoprotein G (gG-2), demonstrates reactivity with all herpes simplex (HSV-2) sera [1]. |
|
T81061 |
Sulfo-Cy5-TCO
|
|
|
|
Sulfo-Cy5-TCO, a water-soluble click chemistry reagent with a TCO group, exhibits high reactivity towards tetrazines and methyltetrazines, facilitating rapid bioconjugation [1]. |
|
T39234 |
BODIPY-TS
|
Thiol-green 2,BODIPY-TS |
|
|
BODIPY-TS (also known as Thiol-green 2) is a highly efficient thiol-specific turn-on probe with a fast response. It incorporates a thiosulfonate scaffold as its thiol recognition unit. BODIPY-TS displays excellent select... |
|
T35967 |
N-methyl-2-HOBA (hydrochloride)
|
|
|
|
N-methyl-2-HOBA is a methylated form of the isoketal scavenger 2-HOBA .1It has low reactivity with isoketals and has no effect on hypertension induced by angiotensin II . N-methyl-2-HOBA has been used as a negative contr... |
|
T81098 |
Stapokibart
|
CM310 |
|
|
Stapokibart (CM310), a humanized monoclonal antibody, selectively binds to IL-4Rα, inhibiting the cytokines IL-4 and IL-13 from interacting with their shared co-receptor subunit, IL-4Rα. This compound demonstrates cross-... |
|
T82660 |
Cy3 methyltetrazine
|
TZ-Cy3 |
|
|
Cy3 Methyltetrazine (TZ-Cy3), a click chemistry reagent featuring methyltetrazine moieties, exhibits high reactivity with cyclooctene. Additionally, as a tetrazine-modified fluorescent probe, it facilitates the analysis ... |
|
T81062 |
Sulfo-Cy5-Methyltetrazine
|
|
|
|
Sulfo-Cy5-Methyltetrazine, a click chemistry reagent with a methyltetrazine group, serves as a fluorophore linker for trans-cyclooctene-based labeling, demonstrating excellent stability at physiological pH and high react... |
|
T63403 |
WT IDH1 Inhibitor 2
|
|
|
|
WT IDH1 Inhibitor 2 is a wild-type isocitrate dehydrogenase 1 (WT IDH1) inhibitor (IC50: 120 nM) and is a mutant R132H IDH1 inhibitor, an isoform of GSK321 with wild-type cross-reactivity. |
|
T81066 |
Sulfo-Cy3-Methyltetrazine
|
|
|
|
Sulfo-Cy3-Methyltetrazine (figure 7 compound 5), a click chemistry reagent, consists of methyltetrazine linked to a water-soluble dye. This compound exhibits good stability at physiological pH and can be efficiently coup... |
|
T80120 |
FITC-εAhx-HHV-2 Envelope Glycoprotein G (561-578)
|
|
HSV
|
|
FITC-εAhx-HHV-2 Envelope Glycoprotein G (561-578) is a fluorescein isothiocyanate (FITC)-labeled segment of the HHV-2 Envelope Glycoprotein G encompassing amino acids 561 to 578. This region is an immunodominant part of ... |
|
T74510 |
TFMU-ADPr
|
|
|
|
TFMU-ADPr serves as a versatile substrate for assessing poly(ADP-ribose) glycohydrolase (PARG) activity, enabling direct measurement of total PAR hydrolase activity through the liberation of a fluorophore. Exhibiting exc... |
|
T80496 |
Kurtoxin
|
|
Calcium Channel
|
|
Kurtoxin is a selective Cav3 (T-type) voltage-gated Ca2+ channel gating inhibitor, exhibiting a dissociation constant (Kd) of 15 nM for the Cav3.1 (α1G T-type) Ca2+ channel. The compound demonstrates high-affinity intera... |
|
T81314 |
Rademikibart
|
CBP-201 |
|
|
Rademikibart (CBP-201) is a human monoclonal antibody selective for IL-4Rα, exhibiting strong affinity with a KD of 20.7 pM for human IL-4Rα epitopes, without cross-reactivity to IL-4Rα from other species. It effectively... |
|
T74511 |
TFMU-ADPr triethylamine
|
|
|
|
TFMU-ADPr triethylamine, a versatile substrate for evaluating poly(ADP-ribose) glycohydrolase (PARG) activity, enables direct measurement of total PAR hydrolase activity through the liberation of a fluorophore. With outs... |
|
T76379 |
Myelopeptide-2
|
|
|
|
Myelopeptide-2, a peptide isolated from the supernatant of porcine bone marrow cell cultures, can restore the mitogenic reactivity of human T lymphocytes inhibited by HL-60 leukemia cells or measles virus conditions. It ... |
|
T35490 |
2-Amino-5-bromo-6-chloropyrazine
|
|
|
|
2-Amino-5-bromo-6-chloropyrazine is a heterocyclic building block.1,2It has been used in the synthesis of Akt inhibitors.
1.Kettle, J.G., Brown, S., Crafter, C., et al.Diverse heterocyclic scaffolds as allosteric inhibit... |
|
T81772 |
MOG (92–106), mouse, rat
|
|
|
|
MOG (92–106), mouse, rat, is a biologically active peptide corresponding to the fragment of amino acids 92 to 106 in myelin oligodendrocyte glycoprotein (MOG) from mice and rats. It is noteworthy that mice subjected to M... |
|
T37697L |
D-GsMTx4 TFA
|
|
TRP/TRPV Channel
,
Piezo Channel
|
|
D-GsMTx4 TFA, a selective spider venom peptide, is a TRPC1/6 and Piezo2 inhibitor that inhibits cation-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families, blocks cation-selective s... |
|
T36504 |
STY-BODIPY
|
STY-BODIPY,Styrene-BODIPY |
|
|
STY-BODIPY is a styrene-conjugated fluorogenic probe for radical-trapping antioxidant (RTA) activity.1 Co-autoxidation of the STY-BODIPY signal carrier and a hydrocarbon co-substrate can be quantified by monitoring the l... |
