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Search Results for " synapses "

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8

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2

天然化合物

22

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T23513 VU10010 VU 10010 AChR
VU10010 (VU 10010) is allosteric potentiator of M4 acetylcholine receptors.
T0333 Aniracetam Ro 13-5057 Dopamine Receptor , 5-HT Receptor , GluR , AChR , iGluR
Aniracetam (Ro 13-5057)(Ro 13-5057), a nootropic and neuroprotective drug, selectively modulates the AMPA receptor and nAChR.
T0939 Phenytoin Diphenylhydantoin,5,5-Diphenylhydantoin Virus Protease , Sodium Channel
Phenytoin (5,5-Diphenylhydantoin) is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin potentially acts by promoting sodium efflux from neurons located in the motor cor...
T20522 Acetylcholine perchlorate AI351678,AI3-51678,AI3 51678
Acetylcholine perchlorate is the perchlorate salt of acetylcholine. Acetylcholine, an endogenous neurotransmitter at cholinergic synapses, could amplify the action potential of the sarcolemma following by inducing muscle...
T76130 Acetylcholinesterase
Acetylcholinesterase (ACHE; EC 3.1.1.7) is a cholinergic enzyme mainly found in neuromuscular junctions and cholinergic type chemical synapses, and is often used in biochemical research. Acetylcholinesterase catalyzes th...
T28653 S-8510 free base SB 737552,SB-737552,S8510,SB737552,S-8510,S 8510
S-8510 is a GABA-A receptor inverse agonist. S-8510 selectively potentiated pentylenetetrazol-induced convulsion without affecting minimal electroconvulsive shock- or strychnine-induced convulsion in ddY mice. S-8510 ame...
T76221 Leptin (116-130)
Leptin (116-130), a bioactive fragment of leptin, enhances synaptic plasticity in the hippocampus by promoting AMPA receptor trafficking to synapses. It preserves hippocampal synapse integrity and prevents neuronal cell ...
T36679 Rp-cAMPS sodium salt
Rp-cAMPS sodium salt, a cAMP analog, is a potent, competitive cAMP-induced activation of cAMP-dependent PKA I and II (Kis of 12.5 μM and 4.5 μM, respectively) antagonist. Rp-cAMPS sodium salt is resistant to hydrolysis b...
カタログ番号 製品名 別名 ターゲット
T26366 Dehydroepiandrosterone sulfate PB 005,PB005,Prasterone sulfate,DHEA sulfate,DHEAS,PB-005 Others
Dehydroepiandrosterone sulfate (PB-005) influences the migration of neurons, arborization of dendrites, and formation of new synapses.
T14011 2-Arachidonoylglycerol Cannabinoid Receptor , Endogenous Metabolite

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPJ-00135 BDNF Protein, Human/Murine/Rat, Recombinant Human,Mouse,Rat E. coli
Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. I...
TMPY-02245 SNAP-25 Protein, Human, Recombinant (His) Human E. coli
Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains...
TMPY-05510 BDNF Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
BDNF is a member of thenerve growth factorfamily. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. B...
TMPH-02555 C1QL1 Protein, Mouse, Recombinant (His) Mouse P. pastoris (Yeast)
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses.
TMPH-02600 C1QL3 Protein, Mouse, Recombinant (His & Myc) Mouse Baculovirus Insect Cells
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. Plays a role in glucose homeostasis. Via AMPK signaling pathway, stimulates glucose uptake in a...
TMPH-02807 NPTXR Protein, Mouse, Recombinant (His & Myc) Mouse Baculovirus Insect Cells
May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
TMPH-02808 NPTX1 Protein, Mouse, Recombinant (His) Mouse E. coli
May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
TMPY-01842 Neuroligin-3/NLGN3 Protein, Human, Recombinant (His) Human HEK293 Cells
Neuroligin 3 (NLGN3) is a member of the type-B carboxylesterase/lipase family. Neuroligins (NLGNs) are a family of presumptive postsynaptic cell adhesion molecules. Neuroligins (NLs) constitute a family of cell-surface p...
TMPY-03750 CRIPT Protein, Human, Recombinant (His) Human E. coli
CRIPT, also known as cysteine-rich PDZ-binding protein, belongs to the CRIPT family. It interacts with TUBB1. CRIPT also interacts strongly with the PDZ3 domain of members of the DLG4 family. It is involved in the cytosk...
TMPH-01085 CHAT Protein, Human, Recombinant (His) Human E. coli
Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses. CHAT Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predic...
TMPK-00612 CSPG5 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
CALEB also known as chondroitin sulfate proteoglycan (CSPG)5 or neuroglycan C, is a neural chondroitin sulfate-containing and epidermal growth factor (EGF)-domain-containing transmembrane protein that is implicated in sy...
TMPJ-01130 NPTX1 Protein, Human, Recombinant (His) Human HEK293 Cells
Neuronal Pentraxin (NPTX1, NP1) is a secreted glycoprotein within the Pentraxin family. NPTX1 is co‑expressed and forms heteromultimers with the related secreted protein, NPTX2/NARP, NPTXR (Neuronal Pentraxin Receptor) a...
TMPH-03280 Dystrophin Protein, Rat, Recombinant (His) Rat P. pastoris (Yeast)
Anchors the extracellular matrix to the cytoskeleton via F-actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variet...
TMPJ-00998 MECP2 Protein, Human, Recombinant (His) Human HEK293 Cells
The MeCP2 helps regulate gene activity (expression) by modifying chromatin, the complex of DNA and protein that packages DNA into chromosomes. The MeCP2 protein is present in cells throughout the body, although it is par...
TMPH-00423 Tetanus toxin Protein, Clostridium tetani, Recombinant (B2M & His) Clostridium tetani E. coli
Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynapt...
TMPY-01742 Acetylcholinesterase Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Acetylcholinesterase, also known as ACHE, is an enzyme that degrades (through its hydrolytic activity) the neurotransmitter acetylcholine, producing choline and an acetate group. Acetylcholinesterase plays a crucial role...
TMPY-02708 NRG4 Protein, Human, Recombinant Human E. coli
NRG4 (neuregulin 4) is a member of the neuregulin protein family. The neuregulins consist of four structurally-related proteins that are part of the EGF family of proteins. It has been shown that these proteins have dive...
TMPY-01165 FZD1/Frizzled 1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Frizzled-1, also known as FZD1, belongs to theG-protein coupled receptor Fz/Smo family. FZD1 contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-term...
TMPY-04070 Citrate Synthase Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Chondroitin sulphate (CS) glycosaminoglycan chains on cell and extracellular matrix proteoglycans (PGs) can no longer be regarded as merely hydrodynamic space fillers. Overwhelming evidence over recent years indicates th...
TMPY-01172 CDH12 Protein, Human, Recombinant (His) Human HEK293 Cells
Classic Cadherins represent a family of calcium-dependent homophilic cell-cell adhesion molecules. They confer strong adhesiveness to animal cells when they are anchored to the actin cytoskeleton via their cytoplasmic bi...
TMPY-02025 CPLX2 Protein, Human, Recombinant (His) Human E. coli
Complexin-2 (CPLX2), a member of the complexin/synaphin family, is a soluble pre-synaptic protein believed to regulate neurotransmitter release from pre-synaptic terminals. Complexins are soluble proteins that regulate t...
TMPH-03753 MYLK Protein, Human, Recombinant (His) Human E. coli
Calcium/calmodulin-dependent myosin light chain kinase implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activity. Phos...
BDNF Protein, Human/Murine/Rat, Recombinant
TMPJ-00135
Species: Human,Mouse,Rat
Expression System: E. coli
SNAP-25 Protein, Human, Recombinant (His)
TMPY-02245
Species: Human
Expression System: E. coli
BDNF Protein, Mouse, Recombinant (His)
TMPY-05510
Species: Mouse
Expression System: HEK293 Cells
C1QL1 Protein, Mouse, Recombinant (His)
TMPH-02555
Species: Mouse
Expression System: P. pastoris (Yeast)
C1QL3 Protein, Mouse, Recombinant (His & Myc)
TMPH-02600
Species: Mouse
Expression System: Baculovirus Insect Cells
NPTXR Protein, Mouse, Recombinant (His & Myc)
TMPH-02807
Species: Mouse
Expression System: Baculovirus Insect Cells
NPTX1 Protein, Mouse, Recombinant (His)
TMPH-02808
Species: Mouse
Expression System: E. coli
Neuroligin-3/NLGN3 Protein, Human, Recombinant (His)
TMPY-01842
Species: Human
Expression System: HEK293 Cells
CRIPT Protein, Human, Recombinant (His)
TMPY-03750
Species: Human
Expression System: E. coli
CHAT Protein, Human, Recombinant (His)
TMPH-01085
Species: Human
Expression System: E. coli
CSPG5 Protein, Mouse, Recombinant (His)
TMPK-00612
Species: Mouse
Expression System: HEK293 Cells
NPTX1 Protein, Human, Recombinant (His)
TMPJ-01130
Species: Human
Expression System: HEK293 Cells
Dystrophin Protein, Rat, Recombinant (His)
TMPH-03280
Species: Rat
Expression System: P. pastoris (Yeast)
MECP2 Protein, Human, Recombinant (His)
TMPJ-00998
Species: Human
Expression System: HEK293 Cells
Tetanus toxin Protein, Clostridium tetani, Recombinant (B2M & His)
TMPH-00423
Species: Clostridium tetani
Expression System: E. coli
Acetylcholinesterase Protein, Mouse, Recombinant (His)
TMPY-01742
Species: Mouse
Expression System: HEK293 Cells
NRG4 Protein, Human, Recombinant
TMPY-02708
Species: Human
Expression System: E. coli
FZD1/Frizzled 1 Protein, Mouse, Recombinant (His)
TMPY-01165
Species: Mouse
Expression System: HEK293 Cells
Citrate Synthase Protein, Human, Recombinant (His)
TMPY-04070
Species: Human
Expression System: Baculovirus Insect Cells
CDH12 Protein, Human, Recombinant (His)
TMPY-01172
Species: Human
Expression System: HEK293 Cells
CPLX2 Protein, Human, Recombinant (His)
TMPY-02025
Species: Human
Expression System: E. coli
MYLK Protein, Human, Recombinant (His)
TMPH-03753
Species: Human
Expression System: E. coli