Powder: -20°C for 3 years | In solvent: -80°C for 1 year
2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors( Ki:300, 80, and 1,900 nM, respectively)
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
10 mg | 在庫あり | ¥ 10,000 | |||
25 mg | 在庫あり | ¥ 15,000 | |||
50 mg | 在庫あり | ¥ 18,500 | |||
100 mg | 在庫あり | ¥ 30,500 | |||
500 mg | 在庫あり | ¥ 77,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 7,000 |
説明 | 2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors( Ki:300, 80, and 1,900 nM, respectively) |
ターゲット&IC50 | A2A:80nM(Ki) , A1:300nM(Ki) , A3:1,900 nM(Ki) |
In vivo | 2-Chloroadenosine(CADO) has been used to activate adenosine receptors in the thalamus, generating anticonvulsive activity in a rat model of generalized seizures.?It has also been used to induce bronchoconstrictor effects in a guinea pig model of asthma and to study cardiovascular responses in normotensive and hypertensive rats |
分子量 | 301.69 |
分子式 | C10H12ClN5O4 |
CAS No. | 146-77-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (149.16 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
2-Chloroadenosine 146-77-0 GPCR/G Protein Neuroscience Adenosine Receptor permeant Inhibitor influx,nitrobenzylthioinosine inhibit cell human 2 Chloroadenosine transported analogue loss 2Chloroadenosine ischaemic erythrocytes,uridine inhibitor