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阻害剤

天然化合物

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カタログ番号	製品名	別名	ターゲット
T2377	Pilaralisib analogue	XL147 analogue,SAR245408	Apoptosis , DNA-PK , PI3K
	Pilaralisib analogue (XL147 analogue) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ.		Apoptosis , DNA-PK , PI3K
T3576	CPI-455 analogue	CPI-455 analogue	Others
	CPI-455 analogue (CPI-455 analogue) is an analogue of CPI-455 which is a KDM5 inhibitor.		Others
T12444	Phentolamine Analogue 1		Adrenergic Receptor
	Phentolamine Analogue 1 is an analogue of phentolamine. Phentolamine is a nonselective antagonist of α-adrenergic.		Adrenergic Receptor
T7944	VPS34 inhibitor 1 (Compound 19, PIK-III analogue)	PIK-III analogue	PI3K
	VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM)		PI3K
T1826	PI3K-IN-1	Voxtalisib Analogue,Voxtalisib (SAR245409, XL765) Analogue,XL765,SAR245409	DNA-PK , PI3K
	PI3K-IN-1 (Voxtalisib Analogue) is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits DNA-PK and mTOR.		DNA-PK , PI3K
T2647	IDO5L	INCB024360 analogue,INCB14943	IDO , Indoleamine 2,3-Dioxygenase (IDO)
	IDO5L (INCB024360 analogue) is an effective IDO1 inhibitor(IC50=10 nM).		IDO , Indoleamine 2,3-Dioxygenase (IDO)
T3076	GLPG0634 analog	GLPG0634 analogue	Tyrosine Kinases , JAK
	GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively.		Tyrosine Kinases , JAK
T6921	ONO-4059 analog	ONO-4059 analogue,ONO-WG-307,GS-4059 analog	Apoptosis , BTK
	ONO-4059 analog (ONO-WG-307)ue is an analogue of ONO-4059, which is a highly potent and selective oral BTK inhibitor with IC50 of 23.9 nM. Phase 1.		Apoptosis , BTK
T6705	TIC10 Isomer	ONC201 isomer,TIC10 Analogue	Others
	TIC10 Isomer (ONC201 isomer) is an isomer of TIC10, which inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improv...		Others
T68855	Hymenialdisine Analogue #1
	Hymenialdisine Analogue #1 is the indole derivative of Hymenialdisine, a potent inhibitor of a variety of kinases including MEK-1, GSK-3Β, and CKI. It also exhibits inhibition of the G2 cell cycle checkpoint at the micro...
T22633	CCT251545 analogue, Compound 51		Others
	CCT251545 analog is a potent and selective CDK8/19 inhibitor (IC50: 5.1 nM and 5.6 nM, respectively). Mediator complex-associated kinases CDK8 and CDK19 are involved in the regulation of multiple transcription pathways. ...		Others
T1806	IDO-IN-7	NLG919,Navoximod,NLG-919 analogue,GDC-0919	Indoleamine 2,3-Dioxygenase (IDO)
	IDO-IN-7 (NLG-919 analogue) is a potent IDO (indoleamine-(2, 3)-dioxygenase) pathway inhibitor.		Indoleamine 2,3-Dioxygenase (IDO)
T11393	GET73	Gamma hydroxybutyric acid analogue,GET 73	GluR
	GET73 (Gamma hydroxybutyric acid analogue) is an negative allosteric modulator of mGluR5. GET73 is a naturally occurring neurotransmitter. GET73 has anti-alcohol and anxiolytic properties.		GluR
T19616	D-phenylalanine analogue	(R)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid	Others
	(R)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid, a constrained phenylalanine (Phe) analogue, exhibits the capacity to adopt beta-bend and helical structures, facilitating a preferred side-chain orientation within th...		Others
T11935	Macitentan (n-butyl analogue)		Others
	Macitentan n-butyl analogue, a derivative of Macitentan, functions as an orally active dual antagonist targeting both endothelin ETA and ETB receptors. This compound shows promise for treating idiopathic pulmonary fibros...		Others
T74641	Rezivertinib analogue 1
	Rezivertinib analogue 1, a process impurity of osimertinib mesylate, serves as a research tool in the study of non-small cell lung cancer (NSCLC) [1].
T11549	Helioxanthin 8-1	Helioxanthin analogue 8-1	Others
	Helioxanthin 8-1, an analogue of helioxanthin, exhibits significant in vitro anti-HBV/HCV/HSV-1/HIV activity with EC50 of >5/10/1.4/15 μM.		Others
TNU0045	β-D-Ribofuranose analogue 1
	Nucleoside Derivatives - 5-Modified pyrimidine nucleosides; Thio-nucleosides; Amino nucleosides; Protected nucleosides w/NH2/OH open
T19858	Brodimoprim		DHFR , Antibacterial
	Brodimoprim is an inhibitor of dihydrofolate reductase(DHFR). Brodimoprim is also a long-acting broad-spectrum antibacterial agent characterized by a good pharmacokinetic profile.		DHFR , Antibacterial
T9162	CID1231538		GPR
	CID1231538 is a potent GPR35 antagonist.		GPR
T38240	2,6-Dichlorodiphenylamine		Antibacterial
	2,6-Dichlorodiphenylamine is an analogue of Diclofenac Sodium and has anti-Candida albicans activity. Diclofenac Sodium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1...		Antibacterial
T15391	Glufosinate ammonium		Others
	Glufosinate ammonium is a phosphinic acid analog of glutamic acid and an herbicide with neurotoxic activity. It is converted by plant cells into PT (L-phosphinothricin).		Others
TP2315	Glatiramer Acetate		Others
	Glatiramer acetate (GA) is a synthetic amino acid copolymer that is approved for treatment of relapsing remitting multiple sclerosis (RRMS) and clinically isolated syndrome (CIS).		Others
T7736	2-Chloroadenosine		Adenosine Receptor
	2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors( Ki:300, 80, and 1,900 nM, respectively)		Adenosine Receptor
T41248	Thiocolchicine		Microtubule Associated
	Thiocolchicine is an effective inhibitor of tubulin polymerization with an IC50 of 2.5 µM and a Ki of 0.7 µM. Thiocolchicine induces cell apoptosis. Thiocolchicine can be used as an ADC cytotoxin in ADC technology.		Microtubule Associated
T9744	MP07-66		Phosphatase
	MP07-66 is a novel FTY720-analog devoid of immunosuppressive effects leads to the reactivation of PP2A, which in turn triggers apoptosis of CLL cells.		Phosphatase
T69840	MX106
	MX106 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.
T0297	Clofarabine	Clofarex,Evoltra,Clolar	Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Autophagy
	Clofarabine (Clofarex)m, a second generation purine nucleoside analog with antineoplastic activity, inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase.
T15588	Iobenguane sulfate	MIBG sulfate	Others
	Iobenguane sulfate (MIBG sulfate) is a high-affinity substrate for cholera toxin that interferes with cellular mono(ADP-ribosylation). Radioiodinated Iobenguane sulfate is clinically used as a tumor-targeted radiopharmac...		Others
T1162	Acipimox	Olbemox,K-9321	Others
	Acipimox (K-9321) is a niacin derivative and nicotinic acid analog with activity as a hypolipidemic agent. Acipimox has special application for the treatment of hyperlipidemia in non-insulin-dependent diabetic patients.		Others
T1646	Famciclovir	BRL 42810	DNA/RNA Synthesis , HSV
	Famciclovir (BRL 42810) is a Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor. The mechanism of action of famciclovir is as a DNA Polymerase Inhibitor, and DNA Polymerase Inhibitor.		DNA/RNA Synthesis , HSV
T4993	Afloqualone	HQ-495	GABA Receptor
	Afloqualone (HQ-495) is a agonist of GABA Receptor . Target: GABA Receptor in vitro: Afloqualone is a quinazolinone family GABAergic drug. It has sedative and muscle-relaxant effects, resulting from its agonist activity ...		GABA Receptor
T1675	Adefovir dipivoxil	Hepsera,GS 0840,Preveon	Others , HBV , Reverse Transcriptase
	Adefovir dipivoxil (GS 0840) is a dipivoxil formulation of adefovir, a nucleoside reverse transcriptase inhibitor analog of adenosine with activity against hepatitis B virus (HBV), herpes virus, and human immunodeficienc...		Others , HBV , Reverse Transcriptase
T0863	Idoxuridine	IDU,SKF 14287,5-Iodo-2′-deoxyuridine,NSC 39661,5-IUdR,Dendrid	Antifection , HSV
	Idoxuridine (Dendrid) is an analog of DEOXYURIDINE that inhibits viral DNA synthesis. The drug is used as an antiviral agent.		Antifection , HSV
T2641	KRCA-0008	KRCA 0008,KRCA0008	ACK , ALK
	KRCA-0008 is an effective and specific ALK/Ack1 inhibitor (IC50: 12/4 nM); displays drug-like properties without hERG liability.		ACK , ALK
T23213	QX-222 chloride	QX 222,Lidocaine N-Methyl Hydrochloride	Sodium Channel
	QX-222 chloride (Lidocaine N-Methyl Hydrochloride) is a sodium channel blocker.		Sodium Channel
T1038	Fludarabine	NSC 118218,Fludarabinum,F-ara-A	Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , STAT
	Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an inhibitor of STAT1 activation. Fludarabine has antitumor activity and can be used for the treatment of leukemia and...
T5882	3-Bromopyruvic acid	Hexokinase II Inhibitor II, 3-BP,Bromopyruvic acid	Apoptosis , Hexokinase , Autophagy
	3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition. It is inhibitor of tumour cell energy metabolism and chemopotentiator of platinu...		Apoptosis , Hexokinase , Autophagy
T1404	Stavudine	d4T,Sanilvudine,BMY-27857,NSC 163661	Apoptosis , Nucleoside Antimetabolite/Analog , HIV Protease , NOD-like Receptor (NLR) , Reverse Transcriptase , Autophagy
	Stavudine (BMY-27857), a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV.
T14489	Azvudine	FNC,RO-0622	HCV Protease , HBV , HIV Protease , Reverse Transcriptase
	Azvudine (FNC) is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine inhibits NRTI-resistant viral strains. Azvudine exerts highly potent inhibition on HIV-1...		HCV Protease , HBV , HIV Protease , Reverse Transcriptase
T60103	N6-(p-Hydroxyphenethyl)-Adenosine)		Others
	N6-(p-Hydroxyphenethyl)-Adenosine) is an adenosine analogue.		Others
T10858	COH34 analog 1		Others
	COH34 analog 1 is a COH34 oxidation analogue that can be used to synthesize active compounds.		Others
T32826	LNA-Adenosine	LNA-A,LNA Adenosine,2'-O,4'-C-Methyleneadenosine	Nucleoside Antimetabolite/Analog
	LNA-Adenosine (LNA-A) is a nucleoside analogue that acts as a ligand for adenosine A3 receptors.		Nucleoside Antimetabolite/Analog
T67816	Alamifovir PM
	Alamifovir PM is an analogue of Alamifovir, an HBV-specific antiviral compound.
T13718	H-Arg(Pbf)-OMe hydrochloride		Others
	H-Arg(Pbf)-OMe hydrochloride is an arginine analogue.		Others
T6507	Gabapentin hydrochloride	Neurontin HCl,Gabapentin HCl	Calcium Channel , GABA Receptor
	Gabapentin hydrochloride (Neurontin HCl) is a GABA analogue, used to treat seizures and neuropathic pain.		Calcium Channel , GABA Receptor
T0445	Promethazine	Proazamine,Diphergan	CaMK , Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR , Histamine Receptor
	Promethazine (Proazamine) is an analogue of anti-glaucoma prostaglandin (PG) .
T14298	Rimiducid		Apoptosis , Others , Fatty Acid Synthase
	Rimiducid is a lipid-permeable tacrolimus analogue, homodimerizing an analogue of human protein fkbp12 and binding to wild-type fkbp12 with 1000-fold lower affinity. Rimiducid is a dimerizer agent that acts by cross-link...		Apoptosis , Others , Fatty Acid Synthase
T6367	Abacavir sulfate	Abacavir Hemisulfate,1592U89,ABC sulfate,Ziagen	Apoptosis , HIV Protease , Reverse Transcriptase
	Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activity		Apoptosis , HIV Protease , Reverse Transcriptase
TP2052L	CTOP acetate		Opioid Receptor
	CTOP acetate is a somatostatin analogue and a μ-opioid receptor antagonist.		Opioid Receptor

Compounds

Pilaralisib analogue

T2377

Synonym: XL147 analogue,SAR245408

Target: Apoptosis, DNA-PK, PI3K

CPI-455 analogue

T3576

Synonym: CPI-455 analogue

Target: Others

Phentolamine Analogue 1

T12444

Synonym:

Target: Adrenergic Receptor

VPS34 inhibitor 1 (Compound 19, PIK-III analogue)

T7944

Synonym: PIK-III analogue

Target: PI3K

PI3K-IN-1

T1826

Synonym: Voxtalisib Analogue,Voxtalisib (SAR245409, XL765) Analogue,XL765,SAR245409

Target: DNA-PK, PI3K

IDO5L

T2647

Synonym: INCB024360 analogue,INCB14943

Target: IDO, Indoleamine 2,3-Dioxygenase (IDO)

GLPG0634 analog

T3076

Synonym: GLPG0634 analogue

Target: Tyrosine Kinases, JAK

ONO-4059 analog

T6921

Synonym: ONO-4059 analogue,ONO-WG-307,GS-4059 analog

Target: Apoptosis, BTK

TIC10 Isomer

T6705

Synonym: ONC201 isomer,TIC10 Analogue

Target: Others

Hymenialdisine Analogue #1

T68855

Synonym:

Target:

CCT251545 analogue, Compound 51

Synonym: NLG919,Navoximod,NLG-919 analogue,GDC-0919

Target: Indoleamine 2,3-Dioxygenase (IDO)

GET73

T11393

Synonym: Gamma hydroxybutyric acid analogue,GET 73

Target: GluR

D-phenylalanine analogue

T19616

Synonym: (R)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid

Target: Others

Macitentan (n-butyl analogue)

T11935

Synonym:

Target: Others

Rezivertinib analogue 1

Synonym: Helioxanthin analogue 8-1

Target: Others

β-D-Ribofuranose analogue 1

Target: DHFR, Antibacterial

2,6-Dichlorodiphenylamine

T38240

Synonym:

Target: Antibacterial

Target: Adenosine Receptor

Thiocolchicine

T41248

Synonym:

Target: Microtubule Associated

Synonym: Clofarex,Evoltra,Clolar

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Autophagy

Iobenguane sulfate

T15588

Synonym: MIBG sulfate

Target: Others

Acipimox

T1162

Synonym: Olbemox,K-9321

Target: DNA/RNA Synthesis, HSV

Afloqualone

T4993

Synonym: HQ-495

Target: GABA Receptor

Adefovir dipivoxil

T1675

Synonym: Hepsera,GS 0840,Preveon

Target: Others, HBV, Reverse Transcriptase

Idoxuridine

T0863

Synonym: IDU,SKF 14287,5-Iodo-2′-deoxyuridine,NSC 39661,5-IUdR,Dendrid

Target: Antifection, HSV

KRCA-0008

T2641

Synonym: KRCA 0008,KRCA0008

Target: ACK, ALK

QX-222 chloride

T23213

Synonym: QX 222,Lidocaine N-Methyl Hydrochloride

Target: Sodium Channel

Fludarabine

T1038

Synonym: NSC 118218,Fludarabinum,F-ara-A

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, STAT

3-Bromopyruvic acid

T5882

Synonym: Hexokinase II Inhibitor II, 3-BP,Bromopyruvic acid

Target: Apoptosis, Hexokinase, Autophagy

Stavudine

T1404

Synonym: d4T,Sanilvudine,BMY-27857,NSC 163661

Target: Apoptosis, Nucleoside Antimetabolite/Analog, HIV Protease, NOD-like Receptor (NLR), Reverse Transcriptase, Autophagy

Azvudine

T14489

Synonym: FNC,RO-0622

Target: HCV Protease, HBV, HIV Protease, Reverse Transcriptase

N6-(p-Hydroxyphenethyl)-Adenosine)

Synonym: LNA-A,LNA Adenosine,2'-O,4'-C-Methyleneadenosine

Target: Nucleoside Antimetabolite/Analog

H-Arg(Pbf)-OMe hydrochloride

T13718

Synonym:

Target: Others

Gabapentin hydrochloride

T6507

Synonym: Neurontin HCl,Gabapentin HCl

Target: Calcium Channel, GABA Receptor

Promethazine

T0445

Synonym: Proazamine,Diphergan

Target: CaMK, Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, AChR, Histamine Receptor

Rimiducid

T14298

Synonym:

Target: Apoptosis, Others, Fatty Acid Synthase

Abacavir sulfate

T6367

Synonym: Abacavir Hemisulfate,1592U89,ABC sulfate,Ziagen

Target: Apoptosis, HIV Protease, Reverse Transcriptase

CTOP acetate

TP2052L

Synonym:

Target: Opioid Receptor

カタログ番号	製品名	別名	ターゲット
T81993	Kadsurin A analogue-1
	Kadsurin A Analogue-1 (Compound 8), a lignan, can be extracted from Piper argyrophylum [1].
T2O2707	D-(+)-Fucose		Others
	1. D-(+)-Fucose is a hexose deoxy sugar found on N-linked glycans that appears on the cell surface of mammalian and plant cells.		Others
T14865	Carboprost tromethamine		Prostaglandin Receptor
	Carboprost tromethamine, a synthetic 15-methyl analogue of prostaglandin F2α, effectively promotes uterine contractions and significantly reduces bleeding during and post-delivery.		Prostaglandin Receptor
T7992	4-Hydroxyflavanone		NO Synthase
	4-Hydroxyflavanone is a natural product, shows full vasorelaxing effects		NO Synthase
T3843	Pinosylvin	3,5-stilbenediol,5-Styrylresorcinol	Apoptosis , Others , Antibacterial , Autophagy
	Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.		Apoptosis , Others , Antibacterial , Autophagy
T13495	3-Amino-2-piperidinone	Cyclo-ornithine	Endogenous Metabolite
	3-Amino-2-piperidinone is a metabolite from all living organisms and can be used as a cyclic ornithine analogue.		Endogenous Metabolite
T13555	Ascr#2	Ascaroside C6	Others
	Ascr#2 (asc-C6-MK) is a glycoside analogue in Cryptococcus hidradii that promotes dauer formation.Ascr#2 mixtures with ascr#3 at low concentrations act as a male elicitor and can be used to detect population density.Ascr...		Others
T13557	Ascr#5	Ascaroside C3	Others
	Ascr#5 (asc-ωC3) is a highly conserved ascoside analogue in Cryptococcus hidradii that modulates a variety of responses in Cryptococcus hidradii.		Others
T6004	Tetrahydropapaverine hydrochloride	Tetrahydropapaverine HCl,Norlaudanosine HCl,Tetrahydroalkali hydrochloride	Hydroxylase
	Tetrahydropapaverine hydrochloride (Norlaudanosine HCl) , an analogue of salsolinol and tetrahydropapaveroline, has neurotoxicity on dopamine neurons.		Hydroxylase
T8084	Dimethyl 4-hydroxyisophthalate	Dimetghyl 4-Hydroxyisophthalate	Others
	Dimethyl 4-hydroxyisophthalate (Dimetghyl 4-Hydroxyisophthalate) is a methyl salicylate analogue, used as a building block in the chemical synthesis.		Others
TN6928	L-Azetidine-2-carboxylic acid	(2S)-azetidine-2-carboxylic acid	Endogenous Metabolite
	L-Azetidine-2-carboxylic acid ((2S)-azetidine-2-carboxylic acid) is a toxic proline analogue produced by members of the Liliaceae and Agavaciae families.		Endogenous Metabolite
T7849	Norspermine		Others
	Norspermine is a polyamine analogue ,used in the treatment of non-small cell lung carcinoma and breast cancer.		Others
T13750	L-Fucitol	1-Deoxy-D-galactitol	Others
	L-Fucitol (1-Deoxy-D-galactitol) is a galactitol analogue isolated from Myristica fragrans (Nutmeg), inhibits galactitol-positive strains of Escherichia coli K12.		Others
T32832	Lobelanidine	NSC-95097,8,10-Diphenyllobelidiol,NSC 95097,NSC95097	AChR
	Lobelanidine (8,10-Diphenyllobelidiol), which can be extracted from the above-ground parts of Lobelia chinensis Lour and Lobelia tupa, is an analogue of lobeline and shows a moderate affinity for nAChR.		AChR
TN2175	Salvianolic acid F		Caspase
	The role of our hybrid molecules, an analogue of Salvianolic acid F, in compelling the glioma cells towards apoptosis by specifically perturbing the concentration of glutathione along with caspase 6.		Caspase
T40569	Hygric acid	N-Methyl-L-proline	Others
	Hygric acid (N-Methyl-L-proline) (N-Methyl-L-proline) is a proline analogue found in the citrus juices and the bergamot juice.		Others
T4S1848	Tubeimoside II	Tubeimoside-B	Others
	Tubeimoside II (also known as Tubeimoside-B), a natural oleanane-type triterpenoid saponin analogue, exhibits anti-inflammatory, antitumor, and antitumor-promoting properties.		Others
T2218	8-Azaguanine	Azaguanine-8,SK 1150,NSC-749,SF-337	Nucleoside Antimetabolite/Analog , Others , Endogenous Metabolite
	8-Azaguanine (SK 1150) is a purine analogue with potential antineoplastic activity.
T1059	Retinyl palmitate	Retinol palmitate,Vitamin A palmitate,Retinyl (Vitamin A) Palmitate	Others , Endogenous Metabolite
	Retinyl palmitate (Vitamin A palmitate) is a naturally-occurring phenyl analogue of retinol, with potential antineoplastic and chemopreventive activities.		Others , Endogenous Metabolite
T3S1960	Kakuol		Antifungal
	1. Kakuol has antifungal activity, it can completely inhibit the mycelial growth of Botrytis cinerea Pers ex Fr and Cladosporium cucumerinum Ellis & Arthur at 5 microg ml(-1) and 3 microg ml(-1), respectively. 2. kakuol ...		Antifungal
T7056	Dronedarone	SR 33589	P450 , Potassium Channel , Calcium Channel , Sodium Channel , Adrenergic Receptor , AChR , Autophagy
	Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.
TL0009	Coniferin	Coniferoside,Abietin	Others , Antifungal
	Coniferin (Abietin) has ATP-dependent transport activity and has anti-oxidation effects. Coniferin has preferred substrates for the coniferin beta-glucosidase, the chromogenic coniferin analogue show the exclusive presen...		Others , Antifungal
T11060	DMAPT	Dimethylamino Parthenolide	NF-κB
	DMAPT (Dimethylamino Parthenolide) is a water-soluble analogue of Parthenolide (PTL). It is an orally active NF-κB inhibitor with an LD50 of 1.7 μM on primary acute myeloid leukemia cells.		NF-κB
T4513	Vanillyl butyl ether	4-(Butoxymethyl)-2-methoxyphenol,Butyl vanillyl ether	Others
	Vanillyl butyl ether (Butyl vanillyl ether) (VBE)is a capsaicin analogue,induce sensory irritation in humans,Vanillyl butyl ether is an alkoxy-substituted benzyl derivative mainly used as a flavoring agent.		Others
T7004	Tubercidin	Sparsomycin A,7-Deazaadenosine	Influenza Virus , DNA/RNA Synthesis , Antibacterial , Antibiotic
	Tubercidin (Sparsomycin A), an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhib...
T1658	Selenomethionine	DL-Selenomethionine,Seleno-DL-methionine	Amino Acids and Derivatives , Endogenous Metabolite , Autophagy
	DL-Selenomethionine (Seleno-DL-methionine) is a selenium (Se) analogue of methionine in which sulfur is replaced with the trace element selenium. Selenomethionine (SeMet) can incorporate into proteins in place of methion...
T30969	Clitocine		Apoptosis , BCL
	Clitocine, an adenosine analogue derived from mushrooms, is a potent transcriptional readout agent, an inhibitor of nonsense mutations, and has anticancer activity, inducing the production of p53 protein in cells carryin...		Apoptosis , BCL
T2S2382	3'-Hydroxypterostilbene	3'-HPT	Apoptosis , Autophagy
	3'-Hydroxypterostilbene (3'-HPT), a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells with IC50s of 9.0, 40.2, and 70.9 μM for COLO 205, HCT-116, and HT-29 cells, respectively, b...		Apoptosis , Autophagy
T1437	D-Panthenol	D-Pantothenyl alcohol,Ilopan,Dexpanthenol,Pantothenol	Endogenous Metabolite
	D-Panthenol (D-Pantothenyl alcohol) is an alcoholic analogue of D-pantothenic acid and cholinergic agent. D-Panthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis...		Endogenous Metabolite
T40657	Epiquinidine
	Epiquinidine, an analogue of quinine, serves as an agonist for ggTas2r1, exhibiting activation at concentrations of 10 μM or higher.
T16673	Pseudouridimycin	PUM	Others
	Pseudouridimycin is a C-nucleoside analogue. Pseudouridimycin is an antibiotic and is a selective bacterial RNA polymerase (RNAP) inhibitor. It is effective against both Gram-negative and Gram-positive bacteria.		Others
T38479	3-Hydroxypyridine
	3-Hydroxypyridine, extracted from Bamboo grass, is a structural analogue of vitamin B6. It exhibits diverse pharmacological properties, including antioxidant activity.
T83235	8-C-Glucosyl-(R)-aloesol	(R)-Aloesinol
	8-C-Glucosyl-(R)-aloesol ((R)-Aloesinol) is a bioactive analogue of chromone [1].
TN2287	Turkesterone		Calcium Channel
	Turkesterone is a phytoecdysteroid possessing an 11alpha-hydroxyl group, also is an analogue of the insect steroid hormone 20-hydroxyecdysone. It has immunomodulating and antistress activity, can increase the adaptation ...		Calcium Channel
T79988	Cytochalasin R
	Cytochalasin R (compound 17), an analogue of cytochalasin, is derived from the endophytic fungus Phomopsis sp. xz-18 and exhibits potential antifungal activity [1].
T40483	8-Aminoadenosine	8-NH2-Ado
	8-Aminoadenosine (8-NH2-Ado) is an RNA-directed nucleoside analogue that effectively diminishes cellular ATP levels and impedes mRNA synthesis. Furthermore, it effectively obstructs Akt/mTOR signaling, inducing autophagy...
T75692	Hypoglaunine D
	Hypoglaunine D, an analogue of Triptonine B, serves as an anti-HIV compound by inhibiting HIV replication in H9 lymphocytes, demonstrating an efficacy with an EC50 value of 22 μg/ml [1].
T39071	Thailanstatin D
	Thailanstatin D, an analogue of Thailanstatin A, inhibits AR-V7 gene splicing by disrupting the interaction between U2AF65 and SAP155, hindering their binding to the polypyrimidine tract situated between the branch point...
T83331	4,5-Dihydroxy-2-((5-methyl-3,8-dimethylene-2-oxododecahydroazuleno[6,5-b]furan-5-yl)oxy)tetrahydro-2H-pyran-3-yl acetate
	4,5-Dihydroxy-2-((5-methyl-3,8-dimethylene-2-oxododecahydroazuleno[6,5-b]furan-5-yl)oxy)tetrahydro-2H-pyran-3-yl acetate is an α-arabinopyranosides analogue isolated from the aboveground parts of barley [1].
T83319	4-epi-Withaferin A
	4-epi-Withaferin A (compound 28), an analogue of Withaferin A, exhibits enhanced cytotoxicity and cytoprotective heat-shock-inducing activity (HSA). It shows promise for the investigation of protein aggregation-associate...
T82032	Isoglobotriaose	Gala-3Galb-4Glc
	Isoglobotriaose (Gala-3Galb-4Glc), a mammalian tissue glycosphingolipid, is a Globotriaose analogue. The ganglioside derivatives of Isoglobotriaose and Globotriaose differ in their small intestine distribution: isoglobot...
T83437	18-O-Demethylpederin
	18-O-Demethylpederin, a pederin analogue, is a natural polyketide first isolated from Paederus. This compound is a non-protein insect toxin and exhibits a range of biological activities, such as antibacterial, antiviral,...
T81201	Sartorypyrone B
	Sartorypyrone B, a 2β-acetoxyl analogue of chevalone C, is derived from the ethyl acetate extract of the culture of Neosartorya tsunodae (KUFC 9213), a fungus associated with marine sponges. This compound demonstrates po...

天然物製品

Kadsurin A analogue-1

Carboprost tromethamine

T14865

Synonym:

Target: Prostaglandin Receptor

Synonym: 3,5-stilbenediol,5-Styrylresorcinol

Target: Apoptosis, Others, Antibacterial, Autophagy

3-Amino-2-piperidinone

T13495

Synonym: Cyclo-ornithine

Target: Endogenous Metabolite

Ascr#2

T13555

Synonym: Ascaroside C6

Target: Others

Ascr#5

T13557

Synonym: Ascaroside C3

Target: Others

Tetrahydropapaverine hydrochloride

T6004

Synonym: Tetrahydropapaverine HCl,Norlaudanosine HCl,Tetrahydroalkali hydrochloride

Target: Hydroxylase

Dimethyl 4-hydroxyisophthalate

T8084

Synonym: Dimetghyl 4-Hydroxyisophthalate

Target: Others

L-Azetidine-2-carboxylic acid

TN6928

Synonym: (2S)-azetidine-2-carboxylic acid

Target: Endogenous Metabolite

Synonym: 1-Deoxy-D-galactitol

Target: Others

Lobelanidine

T32832

Synonym: NSC-95097,8,10-Diphenyllobelidiol,NSC 95097,NSC95097

Synonym: N-Methyl-L-proline

Target: Others

Tubeimoside II

T4S1848

Synonym: Tubeimoside-B

Target: Others

8-Azaguanine

T2218

Synonym: Azaguanine-8,SK 1150,NSC-749,SF-337

Target: Nucleoside Antimetabolite/Analog, Others, Endogenous Metabolite

Retinyl palmitate

T1059

Synonym: Retinol palmitate,Vitamin A palmitate,Retinyl (Vitamin A) Palmitate

Target: Others, Endogenous Metabolite

Target: P450, Potassium Channel, Calcium Channel, Sodium Channel, Adrenergic Receptor, AChR, Autophagy

coniferin

TL0009

Synonym: Coniferoside,Abietin

Target: Others, Antifungal

DMAPT

T11060

Synonym: Dimethylamino Parthenolide

Target: NF-κB

Vanillyl butyl ether

T4513

Synonym: 4-(Butoxymethyl)-2-methoxyphenol,Butyl vanillyl ether

Target: Others

Tubercidin

T7004

Synonym: Sparsomycin A,7-Deazaadenosine

Target: Influenza Virus, DNA/RNA Synthesis, Antibacterial, Antibiotic

Selenomethionine

T1658

Synonym: DL-Selenomethionine,Seleno-DL-methionine

Target: Amino Acids and Derivatives, Endogenous Metabolite, Autophagy

Clitocine

T30969

Synonym:

Target: Apoptosis, BCL

3'-Hydroxypterostilbene

T2S2382

Synonym: 3'-HPT

Target: Apoptosis, Autophagy

D-Panthenol

T1437

Synonym: D-Pantothenyl alcohol,Ilopan,Dexpanthenol,Pantothenol

Target: Endogenous Metabolite

8-C-Glucosyl-(R)-aloesol

T83235

Synonym: (R)-Aloesinol

Target: Calcium Channel

4,5-Dihydroxy-2-((5-methyl-3,8-dimethylene-2-oxododecahydroazuleno[6,5-b]furan-5-yl)oxy)tetrahydro-2H-pyran-3-yl acetate

Synonym: Gala-3Galb-4Glc

カタログ番号	製品名
L1720	Nucleotide Compound Library		334 compounds
	A unique collection of 334 nucleoside and nucleotide analogues, can be used for research and development of anti-viral, anti-tumor, anti-fungal, and anti-depressive drugs;

ライブラリー

Nucleotide Compound Library

L1720

Compounds: 334